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Cited by 154Asthma and respiratory diseasesOccupational exposure and asthmaChronic Obstructive Pulmonary Disease (COPD) Research

The DOI matches its Crossref record; 50 of the 50 references it cites were found in a registry or an index.

The Prevalence of Severe Asthma and Low Asthma Control Among Danish Adults

von Bülow, Anna, Kriegbaum, Margit, Backer, Vibeke, Porsbjerg, Celeste·2014·The Journal of Allergy and Clinical Immunology In Practice
DOI 10.1016/j.jaip.2014.05.005
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Abstract

Background The prevalence of severe asthma is unknown. However, international expert statements estimate that severe asthma represents 5% to 10 % of the entire asthma population.Objective Based on register data from a nationwide population, we wanted to investigate the prevalence of severe asthma, the extent of asthma control, and contact with specialist care.Methods A descriptive cross-sectional register study was performed. By using a nationwide prescription database, we identified current patients with asthma (age, 18-44 years) in 2010. Severity was classified as severe versus mild-moderate asthma according to the level of antiasthma treatment. We investigated prescription drug use, hospitalizations, emergency department visits, and outpatient clinic visits according to severity.Results Among a nationwide population, we identified 61,583 current patients with asthma. Based on the level of antiasthma treatment, 8.1% of identified patients was classified as having severe asthma. Low asthma control (dispensed prescriptions of prednisolone, emergency department visits, hospitalization, or excessive short-acting β₂-agonist use) was more frequent in subjects with severe asthma (36.4% vs 25.2%, P < .0001); 63.8% with severe asthma and low asthma control were not managed by specialist care. Patients with severe asthma with specialist contact more frequently had impaired asthma control compared with subjects not treated by a specialist (44.4% vs 33.1%, P < .0001).Conclusion Based on the level of treatment, 8.1% of a nationwide population of current patients with asthma was classified as having severe asthma. Low asthma control was more frequent among subjects with severe asthma, and only a minority had access to specialist care. There is room for optimizing asthma management, particularly among patients with severe disease.

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  1. Chung, 1999, ERS Task Force: difficult/therapy-resistant asthma, Eur Respir J, 13, 1198

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Metadata

Authors
von Bülow, A., Kriegbaum, M., Backer, V., & Porsbjerg, C.
Affiliations
  • University of Copenhagen (DK)
  • Bispebjerg Hospital (DK)
ORCID
Venue
The Journal of Allergy and Clinical Immunology In Practice
Publisher
Elsevier BV
Published
2014-11
Volume
2
Issue
6
Pages
759-767.e2
ISSN
2213-2198 (ISSN-L)
DOI
10.1016/j.jaip.2014.05.005
OpenAlex
W2019613010
Cited by
154
References
50
Citations by year
2026: 3 · 2025: 11 · 2024: 7 · 2023: 14 · 2022: 21 · 2021: 14 · 2020: 23 · 2019: 20 · 2018: 18 · 2017: 14 · 2016: 5 · 2015: 4
FWCI
5.10
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • The Journal of Allergy and Clinical Immunology In Practice (publishedVersion)
  • PubMed (publishedVersion)
  • Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
Topics
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Occupational exposure and asthma
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
Keywords
severe asthma, asthma prevalence, asthma control, specialist care, hospitalization, emergency department visits, adults, Denmark
MeSH terms
Adolescent, Adult, Age Factors, Ambulatory Care, Asthma, Cross-Sectional Studies, Denmark, Emergency Service, Hospital, Female, Health Resources, Hospitalization, Humans, Lung, Male, Drug Prescriptions, Referral and Consultation, Registries, Severity of Illness Index, Prevalence, Treatment Outcome, Drug Utilization Review, Anti-Asthmatic Agents, Health Care Surveys, Young Adult

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