Pretreatment attrition and childhood social phobia: Parental concerns about medication
Abstract
Pretreatment attrition, the systematic self-exclusion of potential participants during the recruitment phase of a study, poses a significant threat to the external validity of randomized clinical trials. Very little is known about the factors that contribute to pretreatment attrition, especially among families seeking treatment for a child. The current study assessed pretreatment attrition in a randomized clinical trial of behavior therapy, fluoxetine, and placebo for child and adolescent social phobia. Reluctance toward medication treatment accounted for 44.7% of study refusals and was disproportionately common among ethnic minority families. Parents were particularly worried about the potential for side effects or physical/psychological dependency upon the medication. Results are discussed in terms of the implications for external validity in future psychopharmacological clinical trials.
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Ethnic minorities often have a cultural aversion to medication, particularly for mental health problems and especially in children.
“Ethnic minorities often have a cultural aversion to medication, particularly for mental health problems, and especially in children [39, 40]”
From A Sequential Multiple Assignment Randomized Trial (SMART) study of medication and CBT sequencing in the treatment of pediatric anxiety disorders (2021) · cites this paper as [39]
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Cognitive behavioural therapy for anxiety disorders in children and adolescents
James, A. C., James, G., Cowdrey, F. A., Soler, A., & Choke, A. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004690.pub4 · Cited by 876 · see citing works
Cognitive behavioural therapy for anxiety disorders in children and adolescents
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SET-C Versus Fluoxetine in the Treatment of Childhood Social Phobia
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Self-citationA review of studies concerning treatment adherence of patients with anxiety disorders
Fontenelle, L., & Santana (2011) · Patient Preference and Adherence · doi:10.2147/ppa.s23439 · Cited by 82 · see citing works
Treatment preference and recruitment to pediatric RCTs: A systematic review
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Self-citationInnovations in practice: group mindfulness for adolescent anxiety – results of an open trial.
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Peterson, B. S., West, A. E., Weisz, J. R., Mack, W. J., Kipke, M. D., Findling, R. L., Mittman, B. S., Bansal, R., Piantadosi, S., Takata, G., et al. (2021) · BMC Psychiatry · doi:10.1186/s12888-021-03314-y · Cited by 13 · see citing works
- Authors
- Young, B. J., Beidel, D. C., Turner, S. M., Ammerman, R. T., McGraw, K., & Coaston, S. C.
- Venue
- Journal of Anxiety Disorders
- Publisher
- Elsevier BV
- Published
- 2006
- Volume
- 20
- Issue
- 8
- Pages
- 1133-1147
- ISSN
- 0887-6185
- Cited by
- 11
- References
- 5
- Language
- en
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