Cited by 290Immune cells in cancerCardiac Fibrosis and RemodelingPhagocytosis and Immune Regulation

The DOI matches its Crossref record; 123 of the 124 references it cites were found in a registry or an index.

Alternatively activated macrophages in infection and autoimmunity

Open access

Fairweather, DeLisa, Cihakova, Daniela·2009·Journal of Autoimmunity

DOI 10.1016/j.jaut.2009.09.012PMC PMC2783278

Open this paper in CoChat — free account

Abstract

Macrophages are innate immune cells that play an important role in activation of the immune response and wound healing. Pathogens that require T helper-type 2 (Th2) responses for effective clearance, such as parasitic worms, are strong inducers of alternatively activated or M2 macrophages. However, infections such as bacteria and viruses that require Th1-type responses may induce M2 as a strategy to evade the immune system. M2 are particularly efficient at scavenging self tissues following injury through receptors like the mannose receptor and scavenger receptor-A. Thus, M2 may increase autoimmune disease by presenting self tissue to T cells. M2 may also exacerbate immune complex (IC)-mediated pathology and fibrosis, a hallmark of autoimmune disease in women, due to the release of profibrotic factors such as interleukin-1beta, transforming growth factor-beta, fibronectin and matrix metalloproteinases. We have found that M2 comprise anywhere from 30% to 70% of the infiltrate during acute viral or experimental autoimmune myocarditis, and shifts in M2 populations correlate with increased IC deposition, fibrosis and chronic autoimmune pathology. Thus, women may be at an increased risk of M2-mediated autoimmunity due to estrogen's ability to increase Th2 responses.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1016/j.jaut.2009.09.012

Cites

123 of 123 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Macrophage activation and polarization
Martinez, F. O. (2008) · Frontiers in Bioscience · doi:10.2741/2692 · Cited by 3,160
Alternative Activation of Macrophages: An Immunologic Functional Perspective
Martinez, F. O., Helming, L., & Gordon, S. (2009) · Annual Review of Immunology · doi:10.1146/annurev.immunol.021908.132532 · Cited by 2,745
The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions
Nahrendorf, M., Swirski, F. K., Aikawa, E., Stangenberg, L., Wurdinger, T., Figueiredo, J.-L., Libby, P., Weissleder, R., & Pittet, M. J. (2007) · The Journal of Experimental Medicine · doi:10.1084/jem.20070885 · Cited by 2,300
Interleukin 4 potently enhances murine macrophage mannose receptor activity: A marker of alternative immunologic macrophage activation
Stein, M., Keshav, S., Harris, N., & Gordon, S. (1992) · The Journal of experimental medicine · doi:10.1084/jem.176.1.287 · Cited by 1,960
The complex role of estrogens in inflammation
Straub, R. H. (2007) · Endocrine Reviews · doi:10.1210/er.2007-0001 · Cited by 1,950
Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment
Yu, H., Kortylewski, M., & Pardoll, D. M. (2006) · Nature reviews. Immunology · doi:10.1038/nri1995 · Cited by 1,841
Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer
Ostrand‐Rosenberg, S., & Sinha, P. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0802740 · Cited by 1,777
Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease
Monney, L., Sabatos, C. A., Gaglia, J. L., Ryu, A., Waldner, H., Chernova, T., Manning, S., Greenfield, E. A., Coyle, A. J., Sobel, R. A., et al. (2002) · Nature · doi:10.1038/415536a · Cited by 1,677
Epidemiology and estimated population burden of selected autoimmune diseases in the United States
Jacobson, D. L., Gange, S. J., Rose, N. R., & Graham, N. M. H. (1997) · Clinical Immunology and Immunopathology · doi:10.1006/clin.1997.4412 · Cited by 1,667
Altered macrophage differentiation and immune dysfunction in tumor development
Sica, A., & Bronte, V. (2007) · Journal of Clinical Investigation · doi:10.1172/jci31422 · Cited by 1,258

Flagged first, then by citations

Show all 124 references

1 of the 124 references couldn’t be matched to a known paper.

Sorted by citations

Items 201–290 of 290

Attenuated expression of interferon-β and interferon-λ1 by human alternatively activated macrophages
Fiky, A. E., Perreault, R., McGinnis, G. J., & Rabin, R. L. (2013) · Human Immunology · doi:10.1016/j.humimm.2013.08.267 · Cited by 11
Renoprotective effect of epoetin beta pegol by the prevention of M2 macrophage recruitment in Thy-1 rats
Aizawa, K., Tashiro, Y., Hirata, M., Takeda, S., Kawasaki, R., & Endo, K. (2014) · Journal of Nephrology · doi:10.1007/s40620-014-0099-3 · Cited by 11
Regulation of the immune response during infectious myocarditis
Gutierrez, F. R. S., Sesti‐Costa, R., Silva, G. K., Trujillo‐Güiza, M. L., Guedes, P. M. D. M., & Silva, J. S. (2014) · Expert Review of Cardiovascular Therapy · doi:10.1586/14779072.2014.879824 · Cited by 11
Increased neopterin level and chitotriosidase activity in pregnant women with threatened preterm labor
Keskin, U., Ulubay, M., Kurt, Y. G., Fidan, U., Koçyiğit, Y. K., Honca, T., Aydın, F. N., & Ergün, A. (2014) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767058.2014.943174 · Cited by 11
Selenium and Inflammation
Kaushal, N., Gandhi, U. H., Nelson, S. M., Narayan, V., & Prabhu, K. S. (2011) · Springer eBooks · doi:10.1007/978-1-4614-1025-6_35 · Cited by 11
Genetic backgrounds and redox conditions influence morphological characteristics and cell differentiation of osteoclasts in mice
Narahara, S., Matsushima, H., Sakai, E., Fukuma, Y., Nishishita, K., Okamoto, K., & Tsukuba, T. (2012) · Cell and Tissue Research · doi:10.1007/s00441-012-1325-8 · Cited by 10
The Effects of Macrophage Polarity on Influenza Virus Replication and Innate Immune Responses
Dutry, I. (2015) · Journal of Clinical & Cellular Immunology · doi:10.4172/2155-9899.1000297 · Cited by 10
Upregulation of FOXP1 is a new independent unfavorable prognosticator and a specific predictor of lymphatic dissemination in cutaneous melanoma patients
Donizy, P., Pagacz, K., Marczuk, J., Fendler, W. M., Maciejczyk, A., Hałoń, A., & Matkowski, R. (2018) · OncoTargets and Therapy · doi:10.2147/ott.s151286 · Cited by 10
TNFRp55 modulates IL-6 and nitric oxide responses following Yersinia lipopolysaccharide stimulation in peritoneal macrophages
Eliçabe, R. J., Arias, J. L., Rabinovich, G. A., & Genaro, M. S. D. (2011) · Immunobiology · doi:10.1016/j.imbio.2011.05.009 · Cited by 10
Tim4 regulates NALP3 inflammasome expression and activity during monocyte/macrophage dysfunction in septic shock patients
Liu, Z., Tan, K., Bu, L., Bo, L., Ni, W., Fei, M., Chen, F., Deng, X., & Li, J. (2019) · Burns · doi:10.1016/j.burns.2019.08.016 · Cited by 9
Oral administration of taheebo (Tabebuia avellanedae Lorentz ex Griseb.) water extract prevents DSS-induced colitis in mice by up-regulating type II T helper immune responses
Park, H.-J., Lee, S. W., Kwon, D.-J., Heo, S.-I., Park, S.-H., Kim, S. Y., & Hong, S. (2017) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-017-1952-4 · Cited by 9
Possible Critical Role of Latent Chronic Toxoplasma gondii Infection in Triggering, Development and Persistence of Autoimmune Diseases
PRANDOTA, J., & 5 Bartla; Str., 5.-6. W. (2018) · International Journal of Neurology Research · doi:10.17554/j.issn.2313-5611.2018.04.79 · Cited by 9
Using Electrospun Scaffolds to Promote Macrophage Phenotypic Modulation and Support Wound Healing
Hixon, K. R., Dunn, A. J., Flores, R., Minden‐Birkenmaier, B. A., Kalaf, E. A. G., Shornick, L. P., & Sell, S. A. (2017) · Electrospinning · doi:10.1515/esp-2017-0001 · Cited by 9
1,2-Dihydroxyxanthone: Effect on A375-C5 Melanoma Cell Growth Associated with Interference with THP-1 Human Macrophage Activity
Silva, V., Cerqueira, F., Nazareth, N., Medeiros, R., Sarmento, A., Sousa, E., & Pinto, M. M. M. (2019) · Pharmaceuticals · doi:10.3390/ph12020085 · Cited by 8
Using RNA-interference to Investigate the Innate Immune Response in Mouse Macrophages
Arras, L. D., Guthrie, B. S., & Alper, S. (2014) · Journal of Visualized Experiments · doi:10.3791/51306 · Cited by 8
Tug of war: innate immunity and herpes simplex keratitis
Nguyen, P., Jacobs, B., Mohanram, A., Hammons, C., & Xing, J. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1658579 · Cited by 7
Immune-mediated bile duct injury: The case of primary biliary cirrhosis
Selmi, C. F. (2010) · World Journal of Gastrointestinal Pathophysiology · doi:10.4291/wjgp.v1.i4.118 · Cited by 7
Exploiting the preferential phagocytic uptake of nanoparticle-antigen conjugates for the effective treatment of autoimmunity
Sadanandan, P., Payne, N. L., Sun, G., Ashokan, A., Gowd, S. G., Lal, A., Kumar, M. K. S., Pulakkat, S., Nair, S. V., Menon, K. N., et al. (2021) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2021.102481 · Cited by 7
CELLULAR IMMUNOTHERAPY: A MODERN APPROACH TO TREATMENT OF ONCOLOGICAL DISEASES
Lezhnin, Y. N., Khristichenko, A. Y., Ratnikova, N. M., Kravchenko, Y. E., & Chumakov, S. P. (2018) · Medical Immunology (Russia) · doi:10.15789/1563-0625-2018-3-313-340 · Cited by 7
Immunotherapy in Cancer Treatment
Smith, A., Oertle, J. C., III, & Prato, D. (2014) · Open Journal of Medical Microbiology · doi:10.4236/ojmm.2014.43020 · Cited by 6
Paracoccidioidomycosis: characterization of subpopulations of macrophages and cytokines in human mucosal lesions
Pagliari, C., Kanashiro‐Galo, L., Jesus, A. C. C., Saldanha, M. G., & Sotto, M. N. (2018) · Medical Mycology · doi:10.1093/mmy/myy120 · Cited by 6
Mechanisms of Mesenchymal Stem Cells for Autoimmune Disease Treatment
Haque, N., Ramasamy, T. S., & Kasim, N. H. A. (2019) · Stem cells in clinical applications · doi:10.1007/978-3-030-23421-8_2 · Cited by 6
Tumor-associated macrophage is correlated with survival and SOCS protein expression in canine mammary carcinoma
Vieira-Filho, C. H. D. C., Barrouin‐Melo, S. M., Damasceno, K. A., Araújo, M. S. S., Borges, N. F., Silva, F. L., Cassali, G. D., & Estrela‐Lima, A. (2018) · Pesquisa Veterinária Brasileira · doi:10.1590/1678-5150-pvb-5638 · Cited by 5
Role of the Adaptive Immune System in Idiosyncratic Drug-Induced Liver Injury
Uetrecht, J. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-387817-5.00011-x · Cited by 6
Oral Paracoccidioidomycosis Granulomas are Predominantly Populated by CD163+ Multinucleated Giant Cells
Pedreira, R. D. P. G., de Carli, M. L., Beijo, L. A., Nonogaki, S., Pereira, A. A. C., Ribeiro, N. V., Sperandio, F. F., & Hanemann, J. A. C. (2016) · Mycopathologia · doi:10.1007/s11046-016-0016-5 · Cited by 5
Comparison and Analysis on the Existing Single-Herbal Strategies against Viral Myocarditis
Cao, Y., Liu, Y., Zhang, T., Pan, J., Lei, W., & Zhang, B. (2021) · Genetics Research · doi:10.1155/2021/9952620 · Cited by 5
Biomolecular basis of the role of chronic psychological stress hormone ‘‘glucocorticoid’’ in alteration of cellular immunity during cancer
Ahsan, M. R., Mahmud-Al-Rafat, A., Sobhani, M.-E., & Molla, M. A. W. (2013) · memo - Magazine of European Medical Oncology · doi:10.1007/s12254-013-0075-y · Cited by 5
Erianin alleviates autoimmune myocarditis by suppressing the M1 polarization of macrophages via the NF-κB/NLRP3 signaling pathway
Liu, W., Mao, Y., Li, H., Hu, J., Gan, T., Wang, Y., Wang, Z., & Wang, Z. (2025) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2025.177292 · Cited by 5
Reviving ancient therapeutics in modern medicine: an immunological and biological narrative review of wet cupping in the management of Hashimoto’s thyroiditis
Landau, M. B., Abdelmaksoud, A., Hussein, M. H., Jishu, J. A., Fawzy, M. S., Toraih, E. A., & Kandil, E. H. (2024) · Gland Surgery · doi:10.21037/gs-24-173 · Cited by 6
Persistence of HIV-Associated Neurocognitive Disorders in the Era of Antiretroviral Therapy
Jennifer, M. L., Brigid, K., Patrick, J., & Akay, C. (2013) · InTech eBooks · doi:10.5772/52683 · Cited by 4
Macrophage Function in Allergic and Autoimmune Responses
Nazimek, K., Ptak, W., Marcinkiewicz, J., & Bryniarski, K. (2013) · Journal of Physical Therapy and Health Promotion · doi:10.18005/pthp0101005 · Cited by 4
SJSZ glycoprotein (38 kDa) modulates macrophage type 1/2-related factors at hepatocarcinogenic stage in N-nitrosodiethylamine-treated Balb/c
Lee, J. Y., & Lim, K. (2012) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-012-1441-5 · Cited by 4
IFN-γ versus IL-17: A Battle During Cardiac Autoimmunity Evolution
Kurtenbach, E., & Martinez, C. G. (2017) · InTech eBooks · doi:10.5772/66986 · Cited by 3
The Potential Role of Helicobacter pylori-Related Mast Cell Activation in the Progression from Gastroesophageal Reflux to Barrett’s Esophagus and Esophageal Adenocarcinoma
Kazakos, E. I., Petinaki, E. A., Liatsos, C. N., Papanikolaou, I. S., Anastasiadou, K., & Kountouras, J. (2025) · Microorganisms · doi:10.3390/microorganisms13081883 · Cited by 3
A case for the graft-versus-host disease as a model for B cell-mediated autoimmunity
Segalen, I., Fali, T., Pers, J., Meur, Y. L., Youinou, P., & Loisel, S. (2010) · Autoimmunity Reviews · doi:10.1016/j.autrev.2010.10.005 · Cited by 3
Does Dysregulation of Redox State Underpin the Decline of Innate Immunity with Aging?
Griffiths, H. R., Rooney, M. C. O., & Perrie, Y. (2020) · Antioxidants and Redox Signaling · doi:10.1089/ars.2020.8021 · Cited by 3
Immunostimulating activity of Uncaria tomentosa in RAW 264.7 macrophages
Brito, A. S. D., Souza, J. G. D., Filho, A. V. D. M., de Oliveira, P. G., de Oliveira, M. A. P., Barbosa, M. S., de Sousa, J. M. G., Pinto, R. M., da Conceição, E. C., & Braga, C. A. D. S. B. (2023) · Brazilian Journal of Biology · doi:10.1590/1519-6984.271339 · Cited by 3
Delayed presence of alternatively activated macrophages during a Francisella tularensis infection
D’Elia, R. V., Laws, T. R., Núñez, A., Taylor, C., & Clark, G. C. (2014) · Microbial Pathogenesis · doi:10.1016/j.micpath.2014.10.002 · Cited by 3
Effects of mesenchymal stromal cells on monocyte differentiation to M1 phenotype and M1/M2 macrophage switching
Shevela, Е. Y., Sakhno, L. V., Tikhonova, M. A., Васильевич, Б. Е., Ostanin, A. A., & Chernykh, E. R. (2018) · Bulletin of Siberian Medicine · doi:10.20538/1682-0363-2018-1-167-176 · Cited by 3
Pleiotropic Targets: The Problem Of Shared Signaling Circuitry In Rheumatoid Arthritis Disease Progression And Protection
Scheinman, R. I. (2012) · Future Medicinal Chemistry · doi:10.4155/fmc.12.27 · Cited by 2
Epstein-Barr virus (EBV) and systemic lupus erythematosus (SLE) association in serological studies
Czyż, W., Chuncia-Ileczko, M., Wójcikiewicz, M., Arczewski, F., Dziedzic, K., Kulbacka, J., Wojszczyk, M., Zys, D., Pasek, P., & Ryniecka, J. (2025) · Quality in Sport · doi:10.12775/qs.2025.37.57143 · Cited by 2
Atherosclerosis and Inflammatory Heart Disease
Fairweather, D. (2012) · Molecular and integrative toxicology · doi:10.1007/978-1-61779-812-2_11 · Cited by 2
Self-citation
Phagocytosis inMesocestoides vogae-induced peritoneal monocytes/macrophages via opsonin-dependent or independent pathways
Hrčková, G., Vendelova, E., & Velebný, S. (2016) · Helminthologia · doi:10.1515/helmin-2015-0062 · Cited by 2
A1.13 Increased presence of CD206+ macrophage subset in peripheral blood of systemic sclerosis patients
Soldano, S., Contini, P., Brizzolara, R., Montagna, P., Sulli, A., Paolino, S., & Cutolo, M. (2015) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2015-207259.13 · Cited by 2
MRI Investigation of New Approach to Improve the Recovery of Myocardial Ischemia Reperfusion Injury by Treatment with Intralipid®
Wu, Y. L., Liu, L., Yeh, F.-C. F., Rosario, B. L., & Ho, C. (2016) · World Journal of Cardiovascular Diseases · doi:10.4236/wjcd.2016.610041 · Cited by 2
Arzneimittelrechtliche Rahmenbedingungen der extrakorporalen Photopherese
Pannenbecker, A. (2016) · Transfusionsmedizin · doi:10.1055/s-0042-117621 · Cited by 2
Soluble CD206 in metastatic renal cell carcinoma: Relation to clinical–biochemical parameters and patient outcome
Lauridsen, K. M., Møller, H. J., Kristensen, M. W., Fristrup, N., Donskov, F. N., Hokland, M., & Andersen, M. N. (2024) · International Journal of Cancer · doi:10.1002/ijc.35194 · Cited by 2
Optimising chemotherapy for advanced high-grade serous ovarian cancer via delay-differential equations
Koprinski, C., Hawi, G., & Kim, P. (2026) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2026.112396 · Cited by 1
A1.15 Rheumatoid arthritis patients possess a reduced number of IL-10 producing CD27+ regulatory B cells
Bankó, Z., Pozsgay, J., Nagy, G., Gáti, T., Rojkovich, B., & Sármay, G. (2015) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2015-207259.15 · Cited by 1
What is hot in autoimmunity.
Selmi, C. F. (2009) · PubMed · Cited by 1
Gender and Global Health Inequality
Dhatt, R., & Pley, C. (2021) · Springer eBooks · doi:10.1007/978-3-030-05325-3_52-1 · Cited by 2
Role of macrophages in tumor development
Karim, M. R., Hossain, D., Uddin, A. M., & Rume, F. I. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-822368-0.00007-4 · Cited by 2
Local Nasal Inflammation: T Cells and B Cells
Schryver, E. D., Calus, L., Derycke, L., Bachert, C., & Gevaert, P. (2013) · Springer eBooks · doi:10.1007/978-3-642-37250-6_4 · Cited by 1
FACULDADE DE MEDICINA DE RIBEIRÃO PRETO - FMRP PROGRAMA DE PÓS-GRADUAÇÃO EM IMUNOLOGIA BÁSICA E APLICADA
Piñeros, A. R. (2013) · Cited by 1
A General Theory of Autoimmune Disease Causation: Integrating Innate and Adaptive Immunity, Altered Antigen Processing, Sex and Genetic Predispositions, and Microbiome EffectsPreprint
Root-Bernstein, R. S. (2019) · Preprints.org · doi:10.20944/preprints201906.0028.v1
The effect of p(NIPAm-co-AAc) particle chemistry on internalization by activated and non-activated macrophages
Wang, D. (2014) · doi:10.31274/etd-180810-2617
Effect of azithromycin on macrophage phenotype during pulmonary infections and cystic fibrosis
Cory, T. J. (2011) · UKnowledge (University of Kentucky)
HUMORAL AND CELLULAR IMMUNITY FACTORS IN MYOCARDIAL INFARCTION
Seledtsov, V. I., Litvinova, L. S., Seledtsova, I. A., Кириенкова, Е. В., & Shupletsova, V. V. (2014) · Medical Immunology (Russia) · doi:10.15789/1563-0625-2010-6-477-484
Análise da atividade de CD100 na modulação da ativação de macrófagos e sua infectividade por Leishmania (Leishmania) amazonensis.
Galuppo, M. K. (2012) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.42.2012.tde-21092012-085336
Innate Immunity in the CNS – A Focus on the Myeloid Cell
Moore, C. S., Durafourt, B. A., & Antel, J. P. (2014) · Wiley eBooks · doi:10.1002/9781118406557.ch2
Augmenting Anti-Tumor Immunity By Targeting Macrophage Cox-2 In Breast Cancer
Chen, E. P. (2014) · ScholarlyCommons (University of Pennsylvania)
Autophagy Is Required During Monocyte–Macrophage Differentiation
Zhang, Y., Choksi, S., & Liu, Z.-G. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-801043-3.00012-1
Avaliação dos mecanismos imunológicos envolvidos na proteção contra tuberculose no modelo de coinflamação tuberculose-alergia
Piñeros, A. R. (2013) · doi:10.11606/d.17.2013.tde-04082013-181425
P2 B cell depletion therapy exacerbates murine primary biliary cirrhosis
Lleò, A., Bernuzzi, F., Moroni, L., Bianchi, I., DUNN, R. C., Kehry, M. R., Packard, T. A., Cambier, J. C., Podda, M., Gershwin, M. E., et al. (2010) · Digestive and Liver Disease · doi:10.1016/s1590-8658(10)60536-1
Serological diagnostics of myocardium diseases based on multivariate analysis of cardiotrophic autoantibodies’ profiles
Моисеева, О. М., Mitrofanova, L. B., Karelkina, E. V., Зверев, Д. А., Lebedev, D. S., Skurydin, S., & Poletaev, A. B. (2012) · Open Journal of Immunology · doi:10.4236/oji.2012.21006
Angefertigt mit Genehmigung der Mathematisch-Naturwissenschaftlichen Fakultät der
Bonn, R. F.-W.-U. (2012)
Raw 264.7 macrophage-mediated depletion of hydrogen peroxide in cell culture media
Karastathis, D. N. (2011) · cIRcle (University of British Columbia) · doi:10.14288/1.0071613
An initial mapping of the C 2 KO mice phenotype
de Almeida, R. N. A. (2010) · NORA - Norwegian Open Research Archives
Immunology of the Brain
Snelgrove, A. M. G., Galloway, D. A., & Moore, C. S. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-374279-7.19012-5
Innate response to human cytomegalovirus and the role of infections in the pathogenesis of atherosclerosis
Saladrigas, N. R. (2011) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)
Central Nervous System Immune Inflammation
Healy, L. M., Touil, H., Rao, V. T. S., Michell‐Robinson, M. A., Antel, J. P., & Weller, R. O. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-801914-6.00003-9
Chapter 24 – Viral Infection and Heart Disease: Autoimmune Mechanisms
Rose, N., & Afanasyeva, M. (2015) · Elsevier eBooks · doi:10.1016/b978-0-444-63269-2.00026-x
Aktywność biologiczna makrofagów w zdrowiu i chorobie* The biological activity of macrophages in health and disease
Nazimek, K., & Bryniarski, K. (2012)
Development of Animal Models to Study Idiosyncratic Drug-induced Liver Injury
Liu, F. (2015) · TSpace (University of Toronto)
Common mechanisms in neurodegeneration and neuroinflammation: a BrainNet Europe gene expression microarray study Pascal F. DurrenbergerFrancesca S. FernandoSamira N. KashefiTim P. BonnertDanielle Seilhean • Brahim Nait-OumesmarAndrea SchmittPeter J. Gebicke-HaerterPeter FalkaiEdna Grunblatt • Miklos PalkovitsThomas ArzbergerHans KretzschmarDavid T. DexterRichard Reynolds
Wien, S.-V. (2014)
Immunological Response to Haemonchus contortus Antigen in Peripheral Blood Mononuclear Cells of Parasite Resistant and Susceptible Sheep
Jacobs, J. R. (2016) · doi:10.33915/etd.5871
The effect of macrophages on fibroblast activity and lesion development in mouse models of endometriosis.
Johan, M. Z. (2014) · Adelaide Research & Scholarship (AR&S) (University of Adelaide)
Role of Autophagy in the Transition From Monocyte to Differentiation
Zhang, Y., Choksi, S., & Liu, Z.-G. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-812146-7.00004-4
Autophagy is Required during Monocyte–Macrophage Differentiation
Zhang, Y., Choksi, S., & Liu, Z.-G. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-405877-4.00015-9
Avaliação imuno-histoquímica de elementos da resposta imune e metaloproteinases em lesões cutâneas verrucosas na cromoblastomicose
Silva, A. A. D. L. (2019) · doi:10.11606/t.5.2019.tde-20032019-162624
The Innate Immune Receptor Nod1 in Reprogramming the Myeloid Compartment: Implications for Colorectal Cancer
Maisonneuve, C. (2019) · TSpace (University of Toronto)
Investigation of the endocannabinoid system using in vivo and in vitro models
Ternes, S. (2013) · bonndoc (University of Bonn)
Gender and Global Health Inequality
Dhatt, R., & Pley, C. (2021) · Springer eBooks · doi:10.1007/978-3-030-45009-0_52
Innate immunomodulation with MIS416: mechanism of action in experimental autoimmune encephalomyelitis
White, M. P. J. (2015) · doi:10.26686/wgtn.17012330.v1
Biological effect of materials chemistry on soft tissue regeneration
(2024) · Elsevier eBooks · doi:10.1016/b978-0-323-99998-4.00001-8
Immunology of the Brain
Snelgrove, A. M. G., Galloway, D. A., & Moore, C. S. (2016) · Elsevier eBooks · doi:10.1016/b978-0-128-24465-4.00518-4
Encoded Cell‐Material Interactions to Reroute Cytokine Signaling for Regenerative Medicine
Eidman, Z. M., Sharma, J., Lee, J. C., Schulze, N. F., Brien, H. J., Corn, K. C., Rafat, M., & Brunger, J. M. (2026) · Advanced Healthcare Materials · doi:10.1002/adhm.71481
Interactions entre cellules progénitrices et fibroblastes au cours de la régénération pulpo-dentinaire : rôle de l'activation du système du complémént
Chmilewsky, F. (2013) · doi:10.70675/7fde8b8az4988z4588z9c25z811b0d8ea566
Macrophage heterogeneity in organ fibrosis in the era of single-cell omics
Qiu, W., Huang, Y., Chen, J., Chu, C., Shen, Q., & Yan, J. (2026) · Molecular Biology Reports · doi:10.1007/s11033-026-12723-9
Characterisation of the anti-inflammatory effects of marine extracts
McCarthy, C. (2011) · Arrow@dit (Dublin Institute of Technology)

Authors: Fairweather, D., & Cihakova, D.
Affiliations: Johns Hopkins University (US)
Corresponding author: Fairweather, DeLisa
ORCID: Fairweather, DeLisa
Venue: Journal of Autoimmunity
Publisher: Elsevier BV
Published: 2009-11
Volume: 33
Issue: 3-4
Pages: 222-230
ISSN: 0896-8411 (ISSN-L)
DOI: 10.1016/j.jaut.2009.09.012
PMC: PMC2783278
OpenAlex: W2083198686
Cited by: 290
References: 124
Citations by year: 2026: 4 · 2025: 7 · 2024: 8 · 2023: 4 · 2022: 4 · 2021: 11 · 2020: 13 · 2019: 14 · 2018: 16 · 2017: 20 · 2016: 26 · 2015: 18 · 2014: 26 · 2013: 32 · 2012: 36
FWCI: 12.37
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Journal of Autoimmunity (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: Myocarditis Foundation
National Institutes of Health
National Heart, Lung, and Blood Institute (HL 67290, R01HL087033, R01HL067290, HL 70729, R01HL070729, HL087033)
Topics: Life Sciences › Immunology and Microbiology › Immunology › Immune cells in cancer
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Fibrosis and Remodeling
Life Sciences › Immunology and Microbiology › Immunology › Phagocytosis and Immune Regulation
Keywords: M2 macrophages, autoimmunity, infection, Th2 immune response, Th1 response, immune evasion, fibrosis, experimental autoimmune myocarditis, viral infection, estrogen, sex differences, CD206, scavenger receptor A
MeSH terms: Animals, Autoimmune Diseases, Complement System Proteins, Female, Humans, Immunity, Cellular, Infections, Macrophage Activation, Macrophages, Male, Sex Factors, Gonadal Steroid Hormones, Cytokines, Immunity, Humoral

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Alternatively activated macrophages in infection and autoimmunity

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks