PBC Screen: An IgG/IgA dual isotype ELISA detecting multiple mitochondrial and nuclear autoantibodies specific for primary biliary cirrhosis

International Autoimmune Hepatitis Group Report: review of criteria for diagnosis of autoimmune hepatitis

Alvarez, F., Berg, P. A., Bianchi, F. B., Bianchi, L., Burroughs, A. K., Cancado, E. L., Chapman, R. W., Cooksley, W. G. E., Czaja, A. J., Desmet, V. J., et al. (1999) · Journal of Hepatology · doi:10.1016/s0168-8278(99)80297-9 · Cited by 2,903

Primary Biliary Cirrhosis

Kaplan, M. M. (1987) · New England Journal of Medicine · doi:10.1056/nejm198702263160907 · Cited by 2,016

EASL Clinical Practice Guidelines: management of cholestatic liver diseases

European Association for the Study of the Liver (2009) · Journal of Hepatology · doi:10.1016/j.jhep.2009.04.009 · Cited by 1,729

Primary Biliary Cirrhosis

Schwab, M. (2011) · Springer eBooks · doi:10.1007/978-3-642-16483-5_4730 · Cited by 1,241

Primary biliary cirrhosis

Kaplan, M. M., & Gershwin, M. E. (2005) · New England Journal of Medicine · doi:10.1056/nejmra043898 · Cited by 1,144

Primary biliary cirrhosis # †

Lindor, K. D., Gershwin, E. M., Poupon, R., Kaplan, M., Bergasa, N. V., & Heathcote, J. E. (2009) · Hepatology · doi:10.1002/hep.22906 · Cited by 1,099

Primary Biliary Cirrhosis

(2015) · Elsevier eBooks · doi:10.1016/b978-0-323-37755-3.50202-6 · Cited by 808

Autoimmune Hepatitis

Krawitt, E. L. (2006) · New England Journal of Medicine · doi:10.1056/nejmra050408 · Cited by 762

Staging of chronic nonsuppurative destructive cholangitis (syndrome of primary biliary cirrhosis)

Ludwig, J., Dickson, E. R., & McDonald, G. S. A. (1978) · Virchows Archiv A Pathological Anatomy and Histology · doi:10.1007/bf00432479 · Cited by 753

Autoantibodies against nuclear pore complexes are associated with more active and severe liver disease in primary biliary cirrhosis

Invernizzi, P., Podda, M., Battezzati, P. M., Crosignani, A., Zuin, M. G., Hitchman, E., Maggioni, M., Meroni, P. L., Penner, E., & Węsierska‐Gądek, J. (2001) · Journal of Hepatology · doi:10.1016/s0168-8278(00)00040-4 · Cited by 454

Liver autoimmune serology: a consensus statement from the committee for autoimmune serology of the International Autoimmune Hepatitis Group

Vergani, D., Alvarez, F., Bianchi, F. B., Cançado, E. L. R., Mackay, I. R., Manns, M. P., Nishioka, M., & Penner, E. (2004) · Journal of Hepatology · doi:10.1016/j.jhep.2004.08.002 · Cited by 446

Anti-gp210 and anti-centromere antibodies are different risk factors for the progression of primary biliary cirrhosis

Nakamura, M., Kondo, H., Mori, T., Komori, A., Matsuyama, M., Ito, M., Takii, Y., Koyabu, M., Yokoyama, T., Migita, K., et al. (2007) · Hepatology · doi:10.1002/hep.21472 · Cited by 365

Autoantibodies to the Nuclear Sp100 Protein in Primary Biliary Cirrhosis and Associated Diseases: Epitope Specificity and Immunoglobulin Class Distribution

Szostecki, C., Will, H., Netter, H. J., & Guldner, H. H. (1992) · Scandinavian Journal of Immunology · doi:10.1111/j.1365-3083.1992.tb03224.x · Cited by 363

Isolation and characterization of cDNA encoding a human nuclear antigen predominantly recognized by autoantibodies from patients with primary biliary cirrhosis.

Szostecki, C., Guldner, H. H., Netter, H. J., & Will, H. (1990) · The Journal of Immunology · doi:10.4049/jimmunol.145.12.4338 · Cited by 269

Primary Biliary Cirrhosis

Hirschfield, G. M., & Heathcote, E. J. (2010) · Wiley eBooks · doi:10.1002/9781444314403.ch32 · Cited by 261

Definition of human autoimmunity — autoantibodies versus autoimmune disease

Lleò, A., Invernizzi, P., Gao, B., Podda, M., & Gershwin, M. E. (2009) · Autoimmunity Reviews · doi:10.1016/j.autrev.2009.12.002 · Cited by 249

Autoimmune liver serology: Current diagnostic and clinical challenges

Bogdanos, D. P., Invernizzi, P., Mackay, I. R., & Vergani, D. (2008) · World Journal of Gastroenterology · doi:10.3748/wjg.14.3374 · Cited by 213

Detection of Antimitochondrial Autoantibodies in Immunofluorescent Ama–Negative Patients With Primary Biliary Cirrhosis Using Recombinant Autoantigens

Miyakawa, H., Tanaka, A., Kikuchi, K., Matsushita, M., Kitazawa, E., Kawaguchi, N., Fujikawa, H., & Gershwin, E. M. (2001) · Hepatology · doi:10.1053/jhep.2001.26514 · Cited by 200

Correlation of initial autoantibody profile and clinical outcome in primary biliary cirrhosis

Wesierska-Gadek, J., Penner, E., Battezzati, P. M., Selmi, C., Zuin, M., Hitchman, E., Worman, H. J., Gershwin, E. M., Podda, M., & Invernizzi, P. (2006) · Hepatology · doi:10.1002/hep.21172 · Cited by 177

A sensitive bead assay for antimitochondrial antibodies: Chipping away at AMA-negative primary biliary cirrhosis

Oertelt, S., Rieger, R., Selmi, C., Invernizzi, P., Ansari, A. A., Coppel, R. L., Podda, M., Leung, P. S. C., & Gershwin, E. M. (2007) · Hepatology · doi:10.1002/hep.21583 · Cited by 168

Use of A Designer Triple Expression Hybrid Clone for Three Different Lipoyl Domain for the Detection of Antimitochondrial Autoantibodies

Moteki, S., Leung, P. S., Coppel, R. L., Dickson, E. R., Kaplan, M. M., Munoz, S., & Gershwin, M. E. (1996) · Hepatology · doi:10.1002/hep.510240117 · Cited by 152

Long-term follow-up of antimitochondrial antibody-positive autoimmune hepatitis

O'Brien, C., Joshi, S., Feld, J. J., Guindi, M., Dienes, H. P., & Heathcote, E. J. (2008) · Hepatology · doi:10.1002/hep.22380 · Cited by 146

The 210-kD nuclear envelope polypeptide recognized by human autoantibodies in primary biliary cirrhosis is the major glycoprotein of the nuclear pore.

Courvalin, J., Lassoued, K., Bartnik, E., Blobel, G., & Wozniak, R. W. (1990) · Journal of Clinical Investigation · doi:10.1172/jci114696 · Cited by 136

Prevalence and clinical significance of isotype specific antinuclear antibodies in primary biliary cirrhosis

Rigopoulou, E. I., Davies, E. T., Pares, A., Zachou, K., Liaskos, C., Bogdanos, D.-P., Rodes, J., Dalekos, G. N., & Vergani, D. (2005) · Gut · doi:10.1136/gut.2003.036558 · Cited by 134

Interpreting serological tests in diagnosing autoimmune liver diseases

Invernizzi, P., Lleo, A., & Podda, M. (2007) · Seminars in Liver Disease · doi:10.1055/s-2007-979469 · Cited by 107

Specificity and sensitivity of gp210 autoantibodies detected using an enzyme-linked immunosorbent assay and a synthetic polypeptide in the diagnosis of primary biliary cirrhosis

Bandin, O., Courvalin, J., Poupon, R. Y., Dubel, L., Homberg, J., & Johanet, C. (1996) · Hepatology · doi:10.1002/hep.510230512 · Cited by 105

Autoantibodies from patients with primary biliary cirrhosis recognize a restricted region within the cytoplasmic tail of nuclear pore membrane glycoprotein Gp210.

Nickowitz, R. E., & Worman, H. J. (1993) · The Journal of Experimental Medicine · doi:10.1084/jem.178.6.2237 · Cited by 94

Antinuclear Antibodies in Primary Biliary Cirrhosis

Invernizzi, P., Selmi, C., Ranftler, C., Podda, M., & Wȩsierska-Ga̧dek, J. (2005) · Seminars in liver disease (Print) · doi:10.1055/s-2005-916321 · Cited by 87

‘True’ antimitochondrial antibody-negative primary biliary cirrhosis, low sensitivity of the routine assays, or both?

Muratori, P., Muratori, L., Gershwin, M. E., Czaja, A. J., Παππάς, Γ., Maccariello, S., Granito, A., Cassani, F., Loria, P., Lenzi, M., et al. (2003) · Clinical & Experimental Immunology · doi:10.1111/j.1365-2249.2004.02332.x · Cited by 84

Comparative studies of antimitochondrial autoantibodies in sera and bile in primary biliary cirrhosis

Nishio, A., de Water, J. V., Leung, P. S. C., Joplin, R., Neuberger, J., Lake, J. R., Björkland, A., Tötterman, T. H., Peters, M. G., Worman, H. J., et al. (1997) · Hepatology · doi:10.1002/hep.510250506 · Cited by 77

New ELISA for Detecting Primary Biliary Cirrhosis–Specific Antimitochondrial Antibodies

Dähnrich, C., Parés, A. R., Caballería, L., Rosemann, A., Schlumberger, W., Probst, C., Mytilinaiou, M. G., Bogdanos, D. P., Vergani, D., STÖCKER, W., et al. (2009) · Clinical Chemistry · doi:10.1373/clinchem.2008.118299 · Cited by 75

Management of Primary Sclerosing Cholangitis

Lee, Y., & Kaplan, M. M. (2002) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2002.05585.x · Cited by 66

Penetration and Co-localization in MDCK Cell Mitochondria of IgA Derived from Patients with Primary Biliary Cirrhosis

Malmborg, A., Shultz, D. B., Luton, F., Mostov, K. E., Richly, E., Leung, P. S. C., Benson, G. D., Ansari, A. A., Coppel, R. L., Gershwin, M. E., et al. (1998) · Journal of Autoimmunity · doi:10.1006/jaut.1998.0220 · Cited by 63

Diagnostic Relevance and Clinical Significance of the New Enhanced Performance M2 (MIT3) ELISA for the Detection of IgA and IgG Antimitochondrial Antibodies in Primary Biliary Cirrhosis

Gabeta, S., Norman, G., Liaskos, C., Papamichalis, P., Zografos, T., Garagounis, A., Rigopoulou, E., & Dalekos, G. (2007) · Journal of Clinical Immunology · doi:10.1007/s10875-007-9092-0 · Cited by 62

Presence of antimitochondrial autoantibodies in patients with autoimmune hepatitis

Nezu, S., Tanaka, A., Yasui, H., Imamura, M., Nakajima, H., Ishida, H., & Takahashi, S. (2006) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2006.04434.x · Cited by 52

Immunological Study of Anti-M2 in Antimitochondrial Antibody-Negative Primary Biliary Cirrhosis.

KITAMI, N., KOMADA, T., ISHII, H., Shimizu, H., Adachi, H., Yamaguchi, Y., Kitamura, T., Oide, H., Miyazaki, A., Ishikawa, M., et al. (1995) · Internal Medicine · doi:10.2169/internalmedicine.34.496 · Cited by 46

Detection of Gp210 autoantibodies in primary biliary cirrhosis using a recombinant protein containing the predominant autoepitope

Tartakovsky, F., & Worman, H. J. (1995) · Hepatology · doi:10.1002/hep.1840210234 · Cited by 37

Identification of Major Linear Epitopes on the sp100 Nuclear PBC Autoantigen by the Gene-Fragment Phage-Display Technology

Blüthner, M., Schäfer, C., Schneider, C., & Bautz, F. A. (1999) · Autoimmunity · doi:10.3109/08916939908995970 · Cited by 34

Detection of IgA, IgM, and IgG subclasses of anti-M2 antibody by immunoblotting in autoimmune cholangitis: Is autoimmune cholangitis an early stage of primary biliary cirrhosis?

Nakajima, M., Shimizu, H., Miyazaki, A., Watanabe, S., KITAMI, N., & Sato, N. (1999) · Journal of Gastroenterology · doi:10.1007/s005350050380 · Cited by 32

Development of antimitochondrial antibodies in patients with autoimmune hepatitis: Art of facts or an artifact?

Liaskos, C., Bogdanos, D. P., Rigopoulou, E. I., & Dalekos, G. N. (2007) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2006.04751.x · Cited by 24

The diagnostic value of anti-mitochondrial antibodies, especially in primary biliary cirrhosis.

Tanaka, A., Miyakawa, H., Luketic, V. A., Kaplan, M., Storch, W., & Gershwin, M. E. (2002) · PubMed · Cited by 21

In situ nucleic acid detection of PDC-E2, BCOADC-E2, OGDC-E2, PDC-E1α, BCOADC-E1α, OGDC-E1,and the E3 binding protein (protein X) in primary biliary cirrhosis

Harada, K., Sudo, Y., Kono, N., Ozaki, S., Tsuneyama, K., Gershwin, E. M., & Nakanuma, Y. (1999) · Hepatology · doi:10.1002/hep.510300145 · Cited by 21

Evaluation of newly developed ELISA using “MESACUP-2 test mitochondrial M2” kit for the diagnosis of primary biliary cirrhosis

Kadokawa, Y., Omagari, K., Hazama, H., Ohba, K., Masuda, J.-I., Kinoshita, H., Hayashida, K., Isomoto, H., Mizuta, Y., Murase, K., et al. (2003) · Clinical Biochemistry · doi:10.1016/s0009-9120(02)00439-3 · Cited by 18

Automated enzymatic mitochondrial antibody assay for the diagnosis of primary biliary cirrhosis: Applications of a routine diagnostic tool for the detection of antimitochondrial antibodies

Hazama, H., Omagari, K., MASUDA, J., Ohba, K., KINOSHITA, H., MATSUO, I., Isomoto, H., Mizuta, Y., Murase, K., Murata, I., et al. (2002) · Journal of Gastroenterology and Hepatology · doi:10.1046/j.1440-1746.2002.02700.x · Cited by 11

EASL Clinical Practice Guidelines: The diagnosis and management of patients with primary biliary cholangitis.

Hirschfield, G. M., Beuers, U., Corpechot, C., Invernizzi, P., Jones, D., Marzioni, M., & Schramm, C. (2017) · Journal of Hepatology · doi:10.1016/j.jhep.2017.03.022 · Cited by 1,480

The British Society of Gastroenterology/UK-PBC primary biliary cholangitis treatment and management guidelines

Hirschfield, G. M., Dyson, J. K., Alexander, G. J. M., Chapman, M. H., Collier, J., Hübscher, S., Patanwala, I., Pereira, S. P., Thain, C., Thorburn, D., et al. (2018) · Gut · doi:10.1136/gutjnl-2017-315259 · Cited by 362

A randomized trial of obeticholic acid monotherapy in patients with primary biliary cholangitis

Kowdley, K. V., Luketic, V., Chapman, R., Hirschfield, G. M., Poupon, R., Schramm, C., Vincent, C., Rust, C., Parés, A., Mason, A., et al. (2018) · Hepatology · doi:10.1002/hep.29569 · Cited by 281

Primary biliary cholangitis

Lleo, A., Wang, G.-Q., Gershwin, M. E., & Hirschfield, G. M. (2020) · The Lancet · doi:10.1016/s0140-6736(20)31607-x · Cited by 253

Enzyme-Linked Immunosorbent Assay: Types and Applications

Hayrapetyan, H., Tran, T. T., Tellez‐Corrales, E., & Madiraju, C. (2023) · Methods in molecular biology · doi:10.1007/978-1-0716-2903-1_1 · Cited by 208

747 Cytokine production and bone mineral density in patients with primary biliary cirrhosis

Levy, C., Angulo, P., Neuman, M. I., & Lindor, K. D. (2003) · Hepatology · doi:10.1016/s0270-9139(03)80789-9

Incentives in public addiction treatment payment systems: Intended and unintended effects

Reif, S., Stewart, M. T., Horgan, C. M., & Mohr, B. A. (2014) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2014.09.583 · Cited by 1

Diagnostic value of a variety of autoantibodies detection in patients with primary biliary cirrhosis

Zhang, W. (2013) · Chinese Journal of Liver Diseases · Cited by 1

Specificity and sensitivity of gp210 autoantibodies detected using an enzyme-linked immunosorbent assay and a synthetic polypeptide in the diagnosis of primary biliary cirrhosis

Bandin, O., Courvalin, J., Poupon, R. Y., Dubel, L., Homberg, J., & Johanet, C. (1996) · Hepatology · doi:10.1002/hep.510230512 · Cited by 105

Autoantibody profiling of patients with primary biliary cirrhosis using a multiplexed line-blot assay

Villalta, D., Sorrentino, M. C., Girolami, E., Tampoia, M., Alessio, M. G., Brusca, I., Daves, M. L., Porcelli, B., Barberio, G., & Bizzaro, N. (2014) · Use Siena air (University of Siena)