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Paclitaxel Reduces Axonal Bclw to Initiate IP3R1-Dependent Axon Degeneration

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Bcl-2 differentially regulates Ca2+ signals according to the strength of T cell receptor activation

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Melatonin induces apoptosis of colorectal cancer cells through HDAC 4 nuclear import mediated by C a MKII inactivation

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The role of PML in the control of apoptotic cell fate: a new key player at ER–mitochondria sites

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Inhibition of histone H3K79 methylation selectively inhibits proliferation, self-renewal and metastatic potential of breast cancer

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Irbit Mediates Synergy Between Ca2+ and cAMP Signaling Pathways During Epithelial Transport in Mice

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The mitochondria–endoplasmic reticulum contact sites: a signalling platform for cell death

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Activation of Na+/H+ Exchanger NHE3 by Angiotensin II Is Mediated by Inositol 1,4,5-Triphosphate (IP3) Receptor-binding Protein Released with IP3 (IRBIT) and Ca2+/Calmodulin-dependent Protein Kinase II

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Convergence of IRBIT, phosphatidylinositol (4,5) bisphosphate, and WNK/SPAK kinases in regulation of the Na + -HCO 3 − cotransporters family

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Phosphorylated K-Ras limits cell survival by blocking Bcl-xL sensitization of inositol trisphosphate receptors

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Endoplasmic Reticulum–Mitochondria Calcium Communication and the Regulation of Mitochondrial Metabolism in Cancer: A Novel Potential Target

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The BRCA1 Tumor Suppressor Binds to Inositol 1,4,5-Trisphosphate Receptors to Stimulate Apoptotic Calcium Release

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Protein 4.1N Is Required for Translocation of Inositol 1,4,5-Trisphosphate Receptor Type 1 to the Basolateral Membrane Domain in Polarized Madin-Darby Canine Kidney Cells

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IP 3 -mediated gating mechanism of the IP 3 receptor revealed by mutagenesis and X-ray crystallography

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IRBIT controls apoptosis by interacting with the Bcl-2 homolog, Bcl2l10, and by promoting ER-mitochondria contact

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Relief of autoinhibition of the electrogenic Na-HCO3 cotransporter NBCe1-B: role of IRBIT vs. amino-terminal truncation

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Candidate genes for cross-resistance against DNA-damaging drugs.

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The Apoptotic Regulator Nrz Controls Cytoskeletal Dynamics via the Regulation of Ca2+ Trafficking in the Zebrafish Blastula

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A synthetic peptide targeting the BH4 domain of Bcl-2 induces apoptosis in multiple myeloma and follicular lymphoma cells alone or in combination with agents targeting the BH3-binding pocket of Bcl-2

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Phosphorylation of calcium/calmodulin-stimulated protein kinase II at T286 enhances invasion and migration of human breast cancer cells

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IP 3 receptor mutations and brain diseases in human and rodents

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Tyr-167/Trp-168 in Type 1/3 Inositol 1,4,5-Trisphosphate Receptor Mediates Functional Coupling between Ligand Binding and Channel Opening

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The Stability and Expression Level of Bok Are Governed by Binding to Inositol 1,4,5-Trisphosphate Receptors

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IRBIT: A regulator of ion channels and ion transporters

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Protein phosphatase-1 is a novel regulator of the interaction between IRBIT and the inositol 1,4,5-trisphosphate receptor

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The non-apoptotic action of Bcl-xL: regulating Ca2+ signaling and bioenergetics at the ER-mitochondrion interface

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Synergistic killing of human small cell lung cancer cells by the Bcl-2-inositol 1,4,5-trisphosphate receptor disruptor BIRD-2 and the BH3-mimetic ABT-263

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Modulation of Ca2+ Signaling by Anti-apoptotic B-Cell Lymphoma 2 Proteins at the Endoplasmic Reticulum–Mitochondrial Interface

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Endoplasmic reticulum-mitochondria Ca2+ crosstalk in the control of the tumor cell fate

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Structural Studies of Inositol 1,4,5-Trisphosphate Receptor

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IRBIT is a novel regulator of ribonucleotide reductase in higher eukaryotes

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α-CaMKII controls the growth of human osteosarcoma by regulating cell cycle progression

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80K-H Interacts with Inositol 1,4,5-Trisphosphate (IP3) Receptors and Regulates IP3-induced Calcium Release Activity

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Binding of IRBIT to the IP3 receptor: Determinants and functional effects

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Bcl-2 inhibitors as anti-cancer therapeutics: The impact of and on calcium signaling

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The IRBIT domain adds new functions to the AHCY family

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IRBIT regulates CaMKIIα activity and contributes to catecholamine homeostasis through tyrosine hydroxylase phosphorylation

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The trans-membrane domain of Bcl-2α, but not its hydrophobic cleft, is a critical determinant for efficient IP3 receptor inhibition

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The Bcl-2 Homolog Nrz Inhibits Binding of IP 3 to Its Receptor to Control Calcium Signaling During Zebrafish Epiboly

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Combined Phosphoinositide and Ca2+ Signals Mediating Receptor Specificity toward Neuronal Ca2+ Channels

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G-protein-coupled Receptor Kinase-interacting Proteins Inhibit Apoptosis by Inositol 1,4,5-Triphosphate Receptor-mediated Ca2+ Signal Regulation

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Inositol 1,4,5-Triphosphate Receptor-binding Protein Released with Inositol 1,4,5-Triphosphate (IRBIT) Associates with Components of the mRNA 3′ Processing Machinery in a Phosphorylation-dependent Manner and Inhibits Polyadenylation

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Fragmented Inositol 1,4,5-Trisphosphate Receptors Retain Tetrameric Architecture and Form Functional Ca2+ Release Channels

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Alpha-CaMKII Plays a Critical Role in Determining the Aggressive Behavior of Human Osteosarcoma

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Microbial inositol polyphosphate metabolic pathway as drug development target

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Identification of an S-adenosylhomocysteine hydrolase-like transcript induced during dendritic cell differentiation

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Mutations in S-adenosylhomocysteine hydrolase (AHCY) affect its nucleocytoplasmic distribution and capability to interact with S-adenosylhomocysteine hydrolase-like 1 protein

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An IRBIT homologue lacks binding activity to inositol 1,4,5‐trisphosphate receptor due to the unique N‐terminal appendage

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Role for catecholamines in tumor progression

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Paradoxical expression of AHCYL1 affecting ovarian carcinogenesis between chickens and women

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The NHERF1 PDZ1 domain and IRBIT interact and mediate the activation of Na+/H+ exchanger 3 by ANG II

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Caspase 3 cleavage of the inositol 1,4,5-trisphosphate receptor does not contribute to apoptotic calcium release

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PML tumour suppression and beyond: Therapeutic implications

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Splicing variation of Long-IRBIT determines the target selectivity of IRBIT family proteins

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IRBIT Interacts with the Catalytic Core of Phosphatidylinositol Phosphate Kinase Type Iα and IIα through Conserved Catalytic Aspartate Residues

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Metabolic perturbation of epigenome by inhibiting S -adenosylhomocysteine hydrolase elicits senescence through DNA damage response in hepatoma cells

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IRBIT plays an important role in NHE3-mediated pHi regulation in HSG cells

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AMPK, Mitochondrial Function, and Cardiovascular Disease

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The role of mitochondria-associated membranes in cellular homeostasis and diseases

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Structural basis for the regulation of inositol trisphosphate receptors by Ca2+ and IP3

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The aging brain: impact of heavy metal neurotoxicity

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sp²-Iminosugar-glucosidases inhibitor 1-C-octyl-2-oxa-3-oxocastanospermine - induced antiproliferative, apoptotic and necrotic effects in breast cancer cells via targeting GRP78, Stim1 and Orai1

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Altered Ca2+ signaling in cancer cells: Proto-oncogenes and tumor suppressors targeting IP3 receptors

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New Insights in the IP3 Receptor and Its Regulation

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