Effectiveness of manual therapy and home physical therapy in patients with temporomandibular disorders: A randomized controlled trial
Abstract
The purpose of this study was to compare the short-term effectiveness of home physical therapy (HPT) alone with that of manual therapy (MT) in conjunction with home physical therapy (MT-HPT) performed for four weeks in patients with temporomandibular disorders (TMD). Forty subjects (nine males and 31 females; age, 18-72 years) with TMD were randomly divided into two groups: HPT (n = 20; five males and 15 females; mean age, 34.8 ± 12.4 years) and MT-HPT (n = 20; four males and 16 females; mean age, 37.0 ± 14.6 years). Pain intensity was evaluated at rest and with stress using a visual analogue scale (VAS). Pain-free maximum mouth opening (MMO) was also evaluated. Mean change score (MCS) in VAS and the smallest detectable difference (SDD) in pain-free MMO were measured over time. The results were analysed by MANOVA to evaluate the effects of treatment over time. At baseline, the groups did not differ from each other with respect to VAS scores and pain-free MMO (p > 0.05). Within each group, VAS with stress decreased (p < 0.001) and pain-free MMO increased (p < 0.001) over time. Between groups, both time*treatment effect and treatment effect were significant for VAS with stress (p < 0.001); however, only time*treatment effect was significant for pain-free MMO (p = 0.009). In the MT-HPT group, MCS for VAS with stress was 91.3% and SDD for pain-free MMO was 10 mm. Our results suggest that a four-week period of MT-HPT has a clinically significant effect on both pain and pain-free m…
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Manual therapy was effective in reducing pain immediately after treatment, independent of the professional category.
“Manual therapy was found to be effective in reducing pain immediately after treatment, independent of the professional category (Table 2).”
Myofascial release, performed by physiotherapists, chiropractors and dental nurses, showed significant improvements in both pain and function.
“Myofascial release, performed by physiotherapists, chiropractors and dental nurse, showed significant improvements in both pain and function [22,34,35].”
Physiotherapists consistently achieved significant outcomes in pain reductions and maximum mouth opening improvement.
“Physiotherapists consistently achieved significant outcomes in pain reductions [21–23] and MMO improvement [21,22,26].”
Manual therapy was effective across all professional categories, with significant reductions in pain and improvements in maximum mouth opening.
“Manual therapy was effective across all professional categories, with significant reductions in pain [21–25] and improvements in MMO [21–26].”
In this systematic review, most studies applied Axis I criteria, while a subset incorporated both Axis I and II.
“In this systematic review, most studies applied Axis I criteria [22,25,27,30,35], while a subset incorporated both Axis I and II [21,33] to identify TMD subtypes most responsive to manual therapy.”
Myofascial release targeting masticatory and jaw muscles showed consistent efficacy.
“Similarly, myofascial release targeting masticatory and jaw muscles showed consistent efficacy [22].”
Several studies emphasized that manual therapy was performed by professionals with specialized training, reinforcing the notion that clinical expertise is critical to achieving effective results.
“Several studies [21,22,25,26,29,31,34] emphasized that manual therapy was performed by professionals with specialized training, reinforcing the notion that clinical expertise is critical to achieving effective results.”
Pooling results of 2 studies, MT targeted to the orofacial region or in combination with cervical treatment was better than home exercises for the jaw and neck alone or treatment to cervical spine alone for improving mouth opening.
“Pooling the results of the 2 studies 75,105,106 with similar interventions, outcomes, and diagnoses, we found that MT targeted to the orofacial region or in combination with cervical treatment was better than home exercises for the jaw and neck alone or treatment to cervical spine alone for improving mouth opening.”
From Effectiveness of Manual Therapy and Therapeutic Exercise for Temporomandibular Disorders: Systematic Review and Meta-Analysis (2016) · cites this paper as [75]
Eight of the trials reported no adverse events with the treatments.
“Eight of the trials 57,65,67,74,75,77,87,88 reported no adverse events with the treatments.”
From Effectiveness of Manual Therapy and Therapeutic Exercise for Temporomandibular Disorders: Systematic Review and Meta-Analysis (2016) · cites this paper as [75]
Conservative interventions such as physiotherapy and manual therapy directly affect the muscular system to reduce excessive tension and minimize pain in the temporomandibular joints and chewing muscles.
“These interventions directly affect the muscular system, in order to reduce its excessive tension, and thus minimize pain in the area of the temporomandibular joints, and in muscles involved in the chewing process [1,3,19,20,21,22,23,24,25,26].”
From The Application of Manual Techniques in Masticatory Muscles Relaxation as Adjunctive Therapy in the Treatment of Temporomandibular Joint Disorders (2021) · cites this paper as [25]
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Armijo-Olivo, S., Pitance, L., Singh, V., Neto, F., Thie, N., & Michelotti, A. (2016) · Physical Therapy · doi:10.2522/ptj.20140548 · Cited by 413 · see citing works
Urbański, P., Trybulec, B., & Pihut, M. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph182412970 · Cited by 73 · see citing works
The treatment modalities of masticatory muscle pain a network meta-analysis
Feng, J., Luo, M., Ma, J., Tian, Y., Han, X., & Bai, D. (2019) · Medicine · doi:10.1097/md.0000000000017934 · Cited by 23 · see citing works
Chiaramonte, R., Ferrillo, M., de Sire, A., & Vecchio, M. (2026) · Journal of Manual & Manipulative Therapy · doi:10.1080/10669817.2026.2629282
- Authors
- Tuncer, A. B., Ergun, N., Tuncer, A. H., & Karahan, S.
- Affiliations
- Harvard University (US)
- Hacettepe University (TR)
- Venue
- Journal of Bodywork and Movement Therapies
- Publisher
- Elsevier BV
- Published
- 2013-07
- Volume
- 17
- Issue
- 3
- Pages
- 302-308
- ISSN
- 1360-8592 (ISSN-L)
- OpenAlex
- W1992312747
- Cited by
- 133
- References
- 1
- Citations by year
- 2026: 9 · 2025: 17 · 2024: 12 · 2023: 12 · 2022: 8 · 2021: 14 · 2020: 9 · 2019: 9 · 2018: 9 · 2017: 5 · 2016: 13 · 2015: 8 · 2014: 5 · 2013: 3
- FWCI
- 8.45
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Bodywork and Movement Therapies (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Health Professions › Complementary and Manual Therapy › Temporomandibular Joint Disorders
- Health Sciences › Dentistry › Orthodontics › Orthodontics and Dentofacial Orthopedics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Myofascial pain diagnosis and treatment
- Keywords
- temporomandibular disorders, manual therapy, pain intensity, treatment effectiveness, minimal detectable change
- MeSH terms
- Adolescent, Adult, Aged, Female, Humans, Life Style, Longitudinal Studies, Male, Middle Aged, Patient Education as Topic, Self Care, Temporomandibular Joint Disorders, Turkey, Multivariate Analysis, Musculoskeletal Manipulations, Physical Therapy Modalities
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