Cited by 54Nanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesPhotoacoustic and Ultrasonic Imaging

Transferrin modified ruthenium nanoparticles with good biocompatibility for photothermal tumor therapy

Zhao, Shuang, Zhu, Xufeng, Cao, Chengwen, Sun, Jing, Liu, Jie·2018·Journal of Colloid and Interface Science

Abstract

In the past two decades, there were various kinds of photothermal agents being synthesised and investigated for their photothermal effect in antitumor applications. However, it is barely reported that the photothermal effect of Ruthenium (Ru) nanoparticles was researched in depth. In this work, we introduced Ru nanoparticles which possess excellent biocompatibility and metabolize easily to the photothermal therapy field. In addition, to improve the cells capacity of absorbing Ru nanoparticles, these Ru nanoparticles were modified by transferrin (Tf-RuNPs). Subsequently, as is expected, the RuNPs exhibit a remarkably integrated and high-quality photothermal property. On the other hand, it is significantly that Tf modification could also strengthen the cells absorptive ability to uptake Ru nanoparticles through endocytosis., Furthermore, both the in vitro cell ablation and in vivo tumor treatment verified that the Tf-RuNPs became ideal photothermal agents for photothermal tumor ablation therapy owing to their low toxicity and high cell destruction capability.

Integrity signals

Registry

Crossref · 10.1016/j.jcis.2017.10.023

Cites

45 of 45 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Transferrin-coupled or covalently linked nanoparticles endow NPs function of targeting tumors, more effectively realize active targeting of drugs, and achieve tumor diagnosis or treatment.

    “More studies have also proved that transferrin-coupled or covalently linked nanoparticles endow the NPs function of targeting tumors, which can more effectively realize the active targeting of drugs and achieve the purpose of tumor diagnosis or treatment.272–275”

    From Smart nanoparticles for cancer therapy (2023) · cites this paper as [273]

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Zhao, S., Zhu, X., Cao, C., Sun, J., & Liu, J.
Affiliations
Jinan University (CN)
Corresponding author
Liu, Jie
Venue
Journal of Colloid and Interface Science
Publisher
Elsevier BV
Published
2018-02
Volume
511
Pages
325-334
ISSN
0021-9797 (ISSN-L)
OpenAlex
W2762810435
Cited by
54
References
45
Citations by year
2026: 2 · 2025: 6 · 2024: 6 · 2023: 7 · 2022: 5 · 2021: 11 · 2020: 4 · 2019: 6 · 2018: 7
FWCI
2.09
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Colloid and Interface Science (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Natural Science Foundation of China (21171070, 21371075)
  • Natural Science Foundation of Guangdong Province (2014A030311025)
  • Planned Item of Science and Technology of Guangdong Province (2016A020217011)
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Photodynamic Therapy Research Studies
  • Physical Sciences › Engineering › Biomedical Engineering › Photoacoustic and Ultrasonic Imaging
Keywords
ruthenium nanoparticles, photothermal therapy, tumor ablation, biocompatibility, endocytosis, nanoparticle uptake, photothermal agents, nanoparticle toxicity
MeSH terms
A549 Cells, Animals, Humans, Hyperthermia, Induced, Male, Neoplasms, Experimental, Phototherapy, Ruthenium, Transferrin, Mice, SCID, Coated Materials, Biocompatible, Xenograft Model Antitumor Assays, Mice, Metal Nanoparticles, HEK293 Cells

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review