Cited by 218Meta-analysis and systematic reviewsClinical practice guidelines implementationDelphi Technique in Research

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Development of the summary of findings table for network meta-analysis

Yepes-Nuñez, Juan José, Li, Shelly-Anne, Guyatt, Gordon, Jack, Susan M., Brozek, Jan L., Beyene, Joseph, Murad, M. Hassan, Rochwerg, Bram, Mbuagbaw, Lawrence, Zhang, Yuan, Flórez, Ivan D., Siemieniuk, Reed A., Sadeghirad, Behnam, Mustafa, Reem, Santesso, Nancy, Schünemann, Holger J.·2019·Journal of Clinical Epidemiology

DOI 10.1016/j.jclinepi.2019.04.018

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Abstract

Objectives The aim of the study was to develop a Grading of Recommendations, Assessment, Development and Evaluation (GRADE) summary of findings (SoF) table format that displays the critical information from a network meta-analysis (NMA).Study design and setting We applied a user experience model for data analysis based on four rounds of semistructured interviews.Results We interviewed 32 stakeholders who conduct or use MA. Four rounds of interviews produced six candidate NMA-SoF tables. Users found a final NMA-SoF table that included the following components highly acceptable: (1) details of the clinical question (PICO), (2) a plot depicting network geometry, (3) relative and absolute effect estimates, (4) certainty of evidence, (5) ranking of treatments, and (6) interpretation of findings.Conclusion Using stakeholder feedback, we developed a new GRADE NMA-SoF table that includes the relevant components that facilitate understanding NMA findings and health decision-making.

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Authors: Yepes-Nuñez, J. J., Li, S.-A., Guyatt, G., Jack, S. M., Brozek, J. L., Beyene, J., Murad, M. H., Rochwerg, B., Mbuagbaw, L., Zhang, Y., Flórez, I. D., Siemieniuk, R. A., Sadeghirad, B., Mustafa, R., Santesso, N., & Schünemann, H. J.
Affiliations: University of Toronto (CA)
McMaster University (CA)
Mayo Clinic (US)
University of Kansas Medical Center (US)
Corresponding author: Schünemann, Holger J.
ORCID: Yepes-Nuñez, Juan José
Li, Shelly-Anne
Guyatt, Gordon
Jack, Susan M.
Brozek, Jan L.
Murad, M. Hassan
Rochwerg, Bram
Mbuagbaw, Lawrence
Zhang, Yuan
Flórez, Ivan D.
Siemieniuk, Reed A.
Sadeghirad, Behnam
Mustafa, Reem
Santesso, Nancy
Schünemann, Holger J.
Venue: Journal of Clinical Epidemiology
Publisher: Elsevier BV
Published: 2019-11
Volume: 115
Pages: 1-13
ISSN: 0895-4356 (ISSN-L)
DOI: 10.1016/j.jclinepi.2019.04.018
OpenAlex: W2943784761
Cited by: 218
References: 35
Citations by year: 2026: 17 · 2025: 20 · 2024: 28 · 2023: 35 · 2022: 47 · 2021: 31 · 2020: 30 · 2019: 9
FWCI: 19.55
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Journal of Clinical Epidemiology (publishedVersion)
PubMed (publishedVersion)
Topics: Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Clinical practice guidelines implementation
Social Sciences › Sociology and Political Science › Delphi Technique in Research
Keywords: network meta-analysis, summary of findings tables, GRADE, stakeholder feedback, user experience, network geometry, quality of evidence, treatment ranking, health decision-making, PICO
MeSH terms: Abstracting and Indexing, Network Meta-Analysis as Topic, Decision Making, Humans, Evidence-Based Medicine, Information Dissemination, Research Report

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