The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
Potential Usefulness and Clinical Relevance of Adding Left Atrial Strain to Left Atrial Volume Index in the Detection of Left Ventricular Diastolic Dysfunction
Open accessAbstract
OBJECTIVES The purpose of this study was to analyze the potential usefulness and clinical relevance of adding left atrial (LA) strain to left atrial volume index (LAVI) in the detection of left ventricular diastolic dysfunction (LVDD) in patients with preserved left ventricular ejection fraction (LVEF). BACKGROUND Recent studies have suggested that LA strain could be of use in the evaluation of LVDD. However, the potential utility and clinical significance of adding LA strain to LAVI in the detection of LVDD remains uncertain. METHODS Using 2-dimensional speckle-tracking echocardiography, we analyzed a population of 517 patients in sinus rhythm at risk for LVDD such as those with arterial hypertension, diabetes mellitus, or history of coronary artery disease and preserved LVEF. RESULTS In patients with LV diastolic alterations and estimated elevated LV filling pressures, the rate of abnormal LA strain was significantly higher than an abnormal LAVI (62.4% vs. 33.6%, p < 0.01). In line with this, in patients with normal LAVI, high rates of LV diastolic alterations and abnormal LA strain were present (rates 80% and 29.4%, respectively). In agreement with these findings, adding LA strain to LAVI in the current evaluation of LVDD increased significantly the rate of detection of LVDD (relative and absolute increase 73.3% and 9.9%; rate of detection of LVDD: from 13.5% to 23.4%; p < 0.01). Regarding the clinical relevance of these findings, an abnormal LA strain (i.e., <23%) was significantly associated with worse New York Heart Association functional class, even when LAVI was normal. Moreover, in a retrospective post hoc analysis an abnormal LA strain had a significant association with the risk of heart failure hospitalization at 2 years (odds ratio: 6.6 [95% confidence interval: 2.6 to 16.6]) even adjusting this analysis for age and sex and in patients with normal LAVI. CONCLUSIONS The findings from this study provide important insights regarding the potential usefulness and clinical relevance of adding LA strain to LAVI in the detection of LVDD in patients with preserved LVEF.
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Lang, R. M., Badano, L. P., Mor-Avi, V., Afilalo, J., Armstrong, A., Ernande, L., Flachskampf, F. A., Foster, E., Goldstein, S. A., Kuznetsova, T., et al. (2015) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2014.10.003 · Cited by 12,362
Nagueh, S. F., Smiseth, O. A., Appleton, C. P., Byrd, B. F., Dokainish, H., Edvardsen, T., Flachskampf, F. A., Gillebert, T. C., Klein, A. L., Lancellotti, P., et al. (2016) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2016.01.011 · Cited by 5,262
Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography
Nagueh, S. F., Appleton, C. P., Gillebert, T. C., Marino, P. N., Oh, J. K., Smiseth, O. A., Waggoner, A. D., Flachskampf, F. A., Pellikka, P. A., & Evangelista, A. (2009) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2008.11.023 · Cited by 4,367
Tsang, T. S. M., Barnes, M. E., Gersh, B. J., Bailey, K. R., & Seward, J. B. (2002) · The American Journal of Cardiology · doi:10.1016/s0002-9149(02)02864-3 · Cited by 1,166
Prediction of Cardiovascular Outcomes With Left Atrial Size
Tsang, T. S. M., Abhayaratna, W. P., Barnes, M. E., Miyasaka, Y., Gersh, B. J., Bailey, K. R., Cha, S. S., & Seward, J. B. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2005.08.077 · Cited by 773
Nagueh, S. F., Mikati, I., Kopelen, H. A., Middleton, K. J., Quiñones, M. A., & Zoghbi, W. A. (1998) · Circulation · doi:10.1161/01.cir.98.16.1644 · Cited by 596
LA Strain for Categorization of LV Diastolic Dysfunction
Singh, A., Addetia, K., Maffessanti, F., Mor-Avi, V., & Lang, R. M. (2017) · JACC: Cardiovascular Imaging · doi:10.1016/j.jcmg.2016.08.014 · Cited by 458
Freed, B. H., Daruwalla, V., Cheng, J. Y., Aguilar, F. G., Beussink, L., Choi, A., Klein, D. A., Dixon, D., Baldridge, A., Rasmussen-Torvik, L. J., et al. (2016) · Circulation: Cardiovascular Imaging · doi:10.1161/circimaging.115.003754 · Cited by 395
Prognostic Relevance of Left Atrial Dysfunction in Heart Failure With Preserved Ejection Fraction
Santos, A. B. S., Roca, G. Q., Claggett, B., Sweitzer, N. K., Shah, S. J., Anand, I. S., Fang, J. C., Zile, M. R., Pitt, B., Solomon, S. D., et al. (2016) · Circulation: Heart Failure · doi:10.1161/circheartfailure.115.002763 · Cited by 326
Takemoto, Y., Barnes, M. E., Seward, J. B., Lester, S. J., Appleton, C. A., Gersh, B. J., Bailey, K. R., & Tsang, T. S. M. (2005) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2005.05.031 · Cited by 315
Cited by
Pieske, B., Tschöpe, C., de Boer, R. A., Fraser, A. G., Anker, S. D., Donal, E., Edelmann, F., Fu, M., Guazzi, M., Lam, C. S. P., et al. (2020) · European Journal of Heart Failure · doi:10.1002/ejhf.1741 · Cited by 394
Self-citationReddy, Y. N. V., Obokata, M., Egbe, A., Yang, J. H., Pislaru, S., Lin, G., Carter, R., & Borlaug, B. A. (2019) · European Journal of Heart Failure · doi:10.1002/ejhf.1464 · Cited by 316
Metadata
- Authors
- Morris, D. A., Belyavskiy, E., Aravind-Kumar, R., Kropf, M., Frydas, A., Braunauer, K., Marquez, E., Krisper, M., Lindhorst, R., Osmanoglou, E., Boldt, L.-H., Blaschke, F., Haverkamp, W., Tschöpe, C., Edelmann, F., Pieske, B., & Pieske-Kraigher, E.
- Venue
- JACC: Cardiovascular Imaging
- Publisher
- Elsevier BV
- Published
- 2018-10
- Volume
- 11
- Issue
- 10
- Pages
- 1405-1415
- ISSN
- 1876-7591 (ISSN-L)
- 1936-878X
- OpenAlex
- W2768113698
- Cited by
- 388
- References
- 29
- FWCI
- 11.96
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Morris, D. A., Belyavskiy, E., Aravind-Kumar, R., Kropf, M., Frydas, A., Braunauer, K., Marquez, E., Krisper, M., Lindhorst, R., Osmanoglou, E., Boldt, L.-H., Blaschke, F., Haverkamp, W., Tschöpe, C., Edelmann, F., Pieske, B., & Pieske-Kraigher, E. (2018). Potential Usefulness and Clinical Relevance of Adding Left Atrial Strain to Left Atrial Volume Index in the Detection of Left Ventricular Diastolic Dysfunction. JACC: Cardiovascular Imaging. https://doi.org/10.1016/j.jcmg.2017.07.029
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