The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Common delivery systems for enhancing in vivo bioavailability and biological efficacy of nutraceuticals
Open accessAbstract
Abstract Nutraceuticals are an emerging food category defined as dietary elements which can provide health benefits beyond the basic nutritional values. As more compounds have been identified to provide biological benefits, their efficacies are often limited due to insufficient dose efficiency after oral administration. Starting from the mouth, nutraceuticals begin their journey through the gastrointestinal (GI) tract where they are subjected to various physiochemical transformations, from which they may lose their bioactivities completely. To improve the oral efficacy, many edible delivery systems have been developed to enhance the bioavailability of nutraceuticals through various mechanisms. In this article, we first provide a brief overview on biological fate of nutraceuticals in various segments within human GI tract and possible strategies to overcome factors that lead to low bioavailability. A literature review which confirmed the usefulness of different delivery systems to enhance the in vivo oral bioavailability and efficacy of nutraceuticals was also provided.
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Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies
Manach, C., Williamson, G., Morand, C., Scalbert, A., & Rémésy, C. (2005) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/81.1.230s · Cited by 4,219
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Biodegradable, polymeric nanoparticle delivery systems for cancer therapy
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Cited by
The Potential Benefits of Red Beetroot Supplementation in Health and Disease
Clifford, T., Howatson, G., West, D., & Stevenson, E. (2015) · Nutrients · doi:10.3390/nu7042801 · Cited by 635
Aditya, N. P., Aditya, S., Yang, H., Kim, H. W., Park, S. O., & Ko, S. (2015) · Food Chemistry · doi:10.1016/j.foodchem.2014.09.131 · Cited by 337
Biological effects of red beetroot and betalains: A review
Hadipour, E., Taleghani, A., Tayarani‐Najaran, N., & Tayarani‐Najaran, Z. (2020) · Phytotherapy Research · doi:10.1002/ptr.6653 · Cited by 165
Metadata
- Authors
- Ting, Y., Jiang, Y., Ho, C.-T., & Huang, Q.
- Venue
- Journal of Functional Foods
- Publisher
- Elsevier BV
- Published
- 2014-03
- Volume
- 7
- Pages
- 112-128
- ISSN
- 1756-4646 (ISSN-L)
- OpenAlex
- W1979967058
- Cited by
- 327
- References
- 4
- FWCI
- 15.81
- Type
- journal article
- Language
- en
- Open access
- green
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- Ting, Y., Jiang, Y., Ho, C.-T., & Huang, Q. (2014). Common delivery systems for enhancing in vivo bioavailability and biological efficacy of nutraceuticals. Journal of Functional Foods. https://doi.org/10.1016/j.jff.2013.12.010
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