Environmental antimicrobial resistance and its drivers: a potential threat to public health

Origins and evolution of antibiotic resistance

Davies, J., & Davies, D. (2010) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00016-10 · Cited by 5,784

Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study.

Liu, Y.-Y., Wang, Y., Walsh, T., Yi, L.-X., Zhang, R., Spencer, J., Doi, Y., Tian, G.-B., Dong, B.-L., Huang, X.-H., et al. (2016) · Lancet. Infectious Diseases (Print) · doi:10.1016/s1473-3099(15)00424-7 · Cited by 4,920

The antibiotic resistance crisis: part 1: causes and threats.

Ventola, C. L. (2015) · PubMed Central · Cited by 4,558

Antibiotic resistance-the need for global solutions

Laxminarayan, R., Duse, A., Wattal, C., Zaidi, A. K. M., Wertheim, H. F. L., Sumpradit, N., Vlieghe, E., Hara, G. L., Gould, I. M., Goossens, H., et al. (2013) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(13)70318-9 · Cited by 4,439

Global trends in antimicrobial use in food animals

Boeckel, T. V. V., Brower, C., Gilbert, M., Grenfell, B., Levin, S., Robinson, T., Teillant, A., & Laxminarayan, R. (2015) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.1503141112 · Cited by 3,637

Understanding the mechanisms and drivers of antimicrobial resistance

Holmes, A. H., Moore, L. S. P., Sundsfjord, A., Steinbakk, M., Regmi, S., Karkey, A., Guerin, P. J., & Piddock, L. J. V. (2015) · The Lancet · doi:10.1016/s0140-6736(15)00473-0 · Cited by 2,877

Metagenomics: Application of Genomics to Uncultured Microorganisms

Handelsman, J. (2004) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.68.4.669-685.2004 · Cited by 2,528

Food Animals and Antimicrobials: Impacts on Human Health

Marshall, B. M., & Levy, S. B. (2011) · Clinical Microbiology Reviews · doi:10.1128/cmr.00002-11 · Cited by 2,241

Co-selection of antibiotic and metal resistance

Baker‐Austin, C., Wright, M. S., Stepanauskas, R., & McArthur, J. V. (2006) · Trends in Microbiology · doi:10.1016/j.tim.2006.02.006 · Cited by 1,897

Review of antibiotic resistance in China and its environment

Qiao, M., Ying, G., Singer, A. C., & Zhu, Y. (2017) · Environment International · doi:10.1016/j.envint.2017.10.016 · Cited by 1,502

Evidence for effective interventions to reduce mental-health-related stigma and discrimination

Thornicroft, G., Mehta, N., Clement, S., Evans-Lacko, S., Doherty, M., Rose, D., Koschorke, M., Shidhaye, R., O'Reilly, C., & Henderson, C. (2016) · The Lancet · doi:10.1016/s0140-6736(15)00298-6 · Cited by 1,338

Human health risk assessment of antibiotic resistance associated with antibiotic residues in the environment: A review

Ben, Y., Fu, C., Hu, M., Liu, L., Wong, M. H., & Zheng, C. (2018) · Environmental Research · doi:10.1016/j.envres.2018.11.040 · Cited by 1,311

Dissemination of NDM-1 positive bacteria in the New Delhi environment and its implications for human health: an environmental point prevalence study

Walsh, T. R., Weeks, J. L., Livermore, D. M., & Toleman, M. A. (2011) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(11)70059-7 · Cited by 1,255

The World Health Organization Global Action Plan for antimicrobial resistance

Mendelson, M., & Matsoso, M. P. (2015) · South African Medical Journal · doi:10.7196/samj.9644 · Cited by 1,190

Concentrations of antibiotics predicted to select for resistant bacteria: Proposed limits for environmental regulation

Bengtsson‐Palme, J., & Larsson, D. G. J. (2015) · Environment International · doi:10.1016/j.envint.2015.10.015 · Cited by 1,040

BacMet: antibacterial biocide and metal resistance genes database

Pal, C., Bengtsson‐Palme, J., Rensing, C., Kristiansson, E., & Larsson, D. G. J. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt1252 · Cited by 958

The European ban on growth-promoting antibiotics and emerging consequences for human and animal health

Casewell, M. W. (2003) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkg313 · Cited by 949

Antibiotic resistance is the quintessential One Health issue

Robinson, T. P., Bu, D., Carrique-Mas, J. J., Fèvre, E. M., Gilbert, M., Grace, D., Hay, S. I., Jiwakanon, J., Kakkar, M., Kariuki, S., et al. (2016) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1093/trstmh/trw048 · Cited by 904

Rapid evolution and spread of carbapenemases among Enterobacteriaceae in Europe

Cantón, R., Akova, M., Carmeli, Y., Giske, C. G., Glupczynski, Y., Gniadkowski, M., Livermore, D. M., Miriagou, V., Naas, T., Rossolini, G. M., et al. (2012) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2012.03821.x · Cited by 896

Co-occurrence of resistance genes to antibiotics, biocides and metals reveals novel insights into their co-selection potential

Pal, C., Bengtsson‐Palme, J., Kristiansson, E., & Larsson, D. G. J. (2015) · BMC Genomics · doi:10.1186/s12864-015-2153-5 · Cited by 833

Antibiotic resistance is prevalent in an isolated cave microbiome

Bhullar, K., Waglechner, N., Pawlowski, A., Koteva, K., Banks, E. D., Johnston, M. D., Barton, H. A., & Wright, G. D. (2012) · PLoS ONE · doi:10.1371/journal.pone.0034953 · Cited by 736

Human Health Risk Assessment (HHRA) for Environmental Development and Transfer of Antibiotic Resistance

Ashbolt, N. J., Amézquita, A., Backhaus, T., Borriello, P., Brandt, K. K., Collignon, P., Coors, A., Finley, R. L., Gaze, W. H., Heberer, T., et al. (2013) · Environmental Health Perspectives · doi:10.1289/ehp.1206316 · Cited by 662

Global Contributors to Antibiotic Resistance

Chokshi, A., Sifri, Z. C., Cennimo, D. J., & Horng, H. (2019) · Journal of Global Infectious Diseases · doi:10.4103/jgid.jgid_110_18 · Cited by 650

Outer Membrane Vesicles (OMVs) of Gram-negative Bacteria: A Perspective Update

Jan, A. T. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.01053 · Cited by 643

Emergence of resistance to antibacterial agents: the role of quaternary ammonium compounds? A critical review

Buffet-Bataillon, S., Tattevin, P., Bonnaure-Mallet, M., & Jolivet-Gougeon, A. (2012) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2012.01.011 · Cited by 601

Selection of a Multidrug Resistance Plasmid by Sublethal Levels of Antibiotics and Heavy Metals

Gullberg, E., Albrecht, L. M., Karlsson, C., Sandegren, L., & Andersson, D. I. (2014) · mBio · doi:10.1128/mbio.01918-14 · Cited by 590

Molecular Medical Microbiology

(2015) · Elsevier eBooks · doi:10.1016/c2010-1-67744-9 · Cited by 587

Antibiotics in agriculture and the risk to human health: how worried should we be?

Chang, Q., Wang, W., Regev‐Yochay, G., Lipsitch, M., & Hanage, W. P. (2014) · Evolutionary Applications · doi:10.1111/eva.12185 · Cited by 574

Reemergence of antibiotic-resistant Staphylococcus aureus in the genomics era

DeLeo, F. R., & Chambers, H. F. “. (2009) · Journal of Clinical Investigation · doi:10.1172/jci38226 · Cited by 522

Co-occurrence of integrase 1, antibiotic and heavy metal resistance genes in municipal wastewater treatment plants

Cesare, A. D., Eckert, E. M., D'Urso, S., Bertoni, R., Gillan, D. C., Wattiez, R., & Corno, G. (2016) · Water Research · doi:10.1016/j.watres.2016.02.049 · Cited by 509

Resistance to cephalosporins and carbapenems in Gram-negative bacterial pathogens

Pfeifer, Y., Cullik, A., & Witte, W. (2010) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2010.04.005 · Cited by 495

Presence of antibiotic residues in various environmental compartments of Shandong province in eastern China: Its potential for resistance development and ecological and human risk

Hanna, N., Sun, P., Sun, Q., Li, X., Yang, X., Ji, X., Zou, H., Ottoson, J., Nilsson, L. E., Berglund, B., et al. (2018) · Environment International · doi:10.1016/j.envint.2018.02.003 · Cited by 471

Co-Selection of Resistance to Antibiotics, Biocides and Heavy Metals, and Its Relevance to Foodborne Pathogens

Wales, A. D., & Davies, R. (2015) · Antibiotics · doi:10.3390/antibiotics4040567 · Cited by 464

Fecal Colonization With Extended-spectrum Beta-lactamase–Producing Enterobacteriaceae and Risk Factors Among Healthy Individuals: A Systematic Review and Metaanalysis

Karanika, S., Karantanos, T., Arvanitis, M., Grigoras, C. A., & Mylonakis, E. E. (2016) · Clinical Infectious Diseases · doi:10.1093/cid/ciw283 · Cited by 455

Metal Resistance and Its Association With Antibiotic Resistance

Pal, C., Asiani, K., Arya, S., Rensing, C., Stekel, D. J., Larsson, D. G. J., & Hobman, J. L. (2017) · Advances in microbial physiology/Advances in Microbial Physiology · doi:10.1016/bs.ampbs.2017.02.001 · Cited by 444

Assessing the Risk of Antibiotic Resistance Transmission from the Environment to Humans: Non-Direct Proportionality between Abundance and Risk

Manaia, C. M. (2016) · Trends in Microbiology · doi:10.1016/j.tim.2016.11.014 · Cited by 442

Antibiotic Resistance Gene Abundances Correlate with Metal and Geochemical Conditions in Archived Scottish Soils

Knapp, C. W., McCluskey, S. M., Singh, B. K., Campbell, C. D., Hudson, G., & Graham, D. W. (2011) · PLoS ONE · doi:10.1371/journal.pone.0027300 · Cited by 405

Bacterial antimicrobial metal ion resistance

Hobman, J. L., & Crossman, L. C. (2014) · Journal of Medical Microbiology · doi:10.1099/jmm.0.023036-0 · Cited by 401

Antibiotics and common antibacterial biocides stimulate horizontal transfer of resistance at low concentrations

Jutkina, J., Marathe, N. P., Flach, C.-F., & Larsson, D. G. J. (2018) · Science of The Total Environment · doi:10.1016/j.scitotenv.2017.10.312 · Cited by 381

Access to medicines from a health system perspective

Bigdeli, M., Jacobs, B., Tomson, G. B., Laing, R. O., Ghaffar, A., Dujardin, B., & Damme, W. V. (2012) · Health Policy and Planning · doi:10.1093/heapol/czs108 · Cited by 375

The state of the World's Antibiotics 2015.

Gelbrand, H., Miller-Petrie, M. K., Pant, S., Gandra, S., Levinson, J. A., Barter, D., White, A. M., Laxminarayan, R., Ganguly, N., Kariuki, S., et al. (2015) · Cited by 343

Veterinary Drug Residues in Food-animal Products: Its Risk Factors and Potential Effects on Public Health

Tufa, T. B. (2015) · Journal of Veterinary Science & Technology · doi:10.4172/2157-7579.1000285 · Cited by 333

Antimicrobial drug use in food-producing animals and associated human health risks: what, and how strong, is the evidence?

Hoelzer, K., Wong, N. M., Thomas, J., Talkington, K., Jungman, E. R., & Coukell, A. J. (2017) · BMC Veterinary Research · doi:10.1186/s12917-017-1131-3 · Cited by 304

Human, animal and environmental contributors to antibiotic resistance in low-resource settings: integrating behavioural, epidemiological and One Health approaches

Rousham, E. K., UNICOMB, L. E., & Islam, M. A. (2018) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2018.0332 · Cited by 299

Nanosensors for water quality monitoring

Vikesland, P. J. (2018) · Nature Nanotechnology · doi:10.1038/s41565-018-0209-9 · Cited by 296

Causation in epidemiology: Table 1

Parascandola, M. J., & Weed, D. L. (2001) · Journal of Epidemiology & Community Health · doi:10.1136/jech.55.12.905 · Cited by 294

Antibiotics and antibiotic-resistant bacteria in waters associated with a hospital in Ujjain, India

Diwan, V., Tamhankar, A. J., Khandal, R. K., Sen, S., Aggarwal, M., Marothi, Y., Iyer, R. V., Tonderski, K. S., & Lundborg, C. S. (2010) · BMC Public Health · doi:10.1186/1471-2458-10-414 · Cited by 277

Evidence for co-selection of antibiotic resistance genes and mobile genetic elements in metal polluted urban soils

Zhao, Y., Cocerva, T., Cox, S., Tardif, S., Su, J.-Q., Zhu, Y.-G., & Brandt, K. K. (2019) · Science of The Total Environment · doi:10.1016/j.scitotenv.2018.11.372 · Cited by 272

Human–livestock contacts and their relationship to transmission of zoonotic pathogens, a systematic review of literature

Klous, G., Huss, A., Heederik, D. J. J., & Coutinho, R. A. (2016) · One Health · doi:10.1016/j.onehlt.2016.03.001 · Cited by 270

Combination therapies for combating antimicrobial resistance

Fischbach, M. A. (2011) · Current Opinion in Microbiology · doi:10.1016/j.mib.2011.08.003 · Cited by 264

The impact of triclosan on the spread of antibiotic resistance in the environment

Carey, D. E., & McNamara, P. J. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2014.00780 · Cited by 238

ANTIMICROBIAL DRUG RESISTANCE IN STRAINS OF Escherichia coli ISOLATED FROM FOOD SOURCES

Rasheed, M. U., Thajuddin, N., Ahamed, A. P., Teklemariam, Z., & Jamil, K. (2014) · Revista do Instituto de Medicina Tropical de São Paulo · doi:10.1590/s0036-46652014000400012 · Cited by 236

Potential impact of antimicrobial resistance in wildlife, environment and human health

Radhouani, H., Silva, N. A., Poeta, P. A. C. Q. D., Torres, C., Correia, S., & Igrejas, G. (2014) · Frontiers in Microbiology · doi:10.3389/fmicb.2014.00023 · Cited by 233

Non-antibiotic antimicrobial triclosan induces multiple antibiotic resistance through genetic mutation

Lu, J., Jin, M., Nguyen, S. H., Mao, L., Li, J., Coin, L., Yuan, Z., & Guo, J. (2018) · Environment International · doi:10.1016/j.envint.2018.06.004 · Cited by 225

Antimicrobial Drug Use in Veterinary Medicine

Morley, P. S., Apley, M. D., Besser, T. E., Burney, D. P., Fedorka–Cray, P. J., Papich, M. G., Traub‐Dargatz, J. L., & Weese, J. S. (2005) · Journal of Veterinary Internal Medicine · doi:10.1111/j.1939-1676.2005.tb02739.x · Cited by 220

Antibiotics and Antibiotic Resistance in Agroecosystems: State of the Science

Williams-Nguyen, J. S., Sallach, J. B., Bartelt‐Hunt, S. L., Boxall, A. B. A., Durso, L. M., McLain, J. E., Singer, R. S., Snow, D. D., & Zilles, J. L. (2016) · Journal of Environmental Quality · doi:10.2134/jeq2015.07.0336 · Cited by 214

Bacterial characteristics of importance for recurrent urinary tract infections caused by Escherichia coli.

Ejrnæs, K. (2011) · PubMed · Cited by 207

The analysis of animal faeces as a tool to monitor antibiotic usage

Berendsen, B. J. A., Wegh, R. S., Memelink, J., Zuidema, T., & Stolker, L. (2014) · Talanta · doi:10.1016/j.talanta.2014.09.022 · Cited by 205

Occurrence of the mcr-1 Colistin Resistance Gene and other Clinically Relevant Antibiotic Resistance Genes in Microbial Populations at Different Municipal Wastewater Treatment Plants in Germany

Hembach, N., Schmid, F., Alexander, J., Hiller, C., Rogall, E. T., & Schwartz, T. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.01282 · Cited by 190

Antimicrobial Resistance, Virulence Factors and Genetic Diversity of Escherichia coli Isolates from Household Water Supply in Dhaka, Bangladesh

Talukdar, P. K., Rahman, M., Rahman, M., Nabi, A., Islam, Z., Hoque, M. M., Endtz, H. P., & Islam, M. A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0061090 · Cited by 189

Multidrug-resistant Gram-negative bacteria: a product of globalization

Hawkey, P. M. (2015) · Journal of Hospital Infection · doi:10.1016/j.jhin.2015.01.008 · Cited by 183

Relationship between antibiotic resistance genes and metals in residential soil samples from Western Australia

Knapp, C. W., Callan, A. C., Aitken, B., Shearn, R., Koenders, A., & Hinwood, A. L. (2016) · Environmental Science and Pollution Research · doi:10.1007/s11356-016-7997-y · Cited by 183

Antidepressant fluoxetine induces multiple antibiotics resistance in Escherichia coli via ROS-mediated mutagenesis

Jin, M., Lu, J., Chen, Z., Nguyen, S. H., Mao, L., Li, J., Yuan, Z., & Guo, J. (2018) · Environment International · doi:10.1016/j.envint.2018.07.046 · Cited by 182

Abundances of Tetracycline, Sulphonamide and Beta-Lactam Antibiotic Resistance Genes in Conventional Wastewater Treatment Plants (WWTPs) with Different Waste Load

Laht, M., Karkman, A., Voolaid, V., Ritz, C., Tenson, T., Virta, M., & Kisand, V. (2014) · PLoS ONE · doi:10.1371/journal.pone.0103705 · Cited by 181

Antibiotic-Resistant Bacteria: Prevalence in Food and Inactivation by Food-Compatible Compounds and Plant Extracts

Friedman, M. (2015) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.5b00778 · Cited by 173

Antibiotic Resistance Genes in the Human-Impacted Environment: A One Health Perspective

Tiedje, J. M., Wang, F., Manaia, C. M., Virta, M., Sheng, H., Ma, L., Zhang, T., & Topp, E. (2019) · Pedosphere · doi:10.1016/s1002-0160(18)60062-1 · Cited by 167

Occurrence of generic Escherichia coli, E. coli O157 and Salmonella spp. in water and sediment from leafy green produce farms and streams on the Central California coast

Benjamin, L., Atwill, E. R., Jay‐Russell, M. T., Cooley, M. B., Carychao, D. K., Gorski, L., & Mandrell, R. E. (2013) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2013.04.003 · Cited by 165

Policy: An intergovernmental panel on antimicrobial resistance

Woolhouse, M. E. J., & Farrar, J. (2014) · Nature · doi:10.1038/509555a · Cited by 159

Antimicrobial Usage in Chicken Production in the Mekong Delta of Vietnam

Carrique-Mas, J. J., Trung, N. V., Hoa, N. T., Mai, H. H., Thanh, T. H., Campbell, J. I., Wagenaar, J. A., Hardon, A. P., Hieu, T. Q., & Schultsz, C. (2014) · Zoonoses and Public Health · doi:10.1111/zph.12165 · Cited by 159

Fate and proliferation of typical antibiotic resistance genes in five full-scale pharmaceutical wastewater treatment plants

Wang, J., Mao, D., Mu, Q., & Luo, Y. (2015) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2015.05.046 · Cited by 157

Methicillin-Resistant Staphylococcus aureus in Pigs and Farm Workers on Conventional and Antibiotic-Free Swine Farms in the USA

Smith, T. C., Gebreyes, W. A., Abley, M. J., Harper, A. L., Forshey, B. M., Male, M. J., Martin, H., Molla, B. Z., Sreevatsan, S., Thakur, S., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0063704 · Cited by 156

Parallel evolutionary pathways to antibiotic resistance selected by biocide exposure

Webber, M. A., Whitehead, R. N., Mount, M., Loman, N. J., Pallen, M. J., & Piddock, L. J. V. (2015) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkv109 · Cited by 155

Zoonotic Disease Programs for Enhancing Global Health Security

Belay, E. D., Kile, J. C., Hall, A. J., Behravesh, C. B., Parsons, M. B., Salyer, S. J., & Walke, H. T. (2017) · Emerging infectious diseases · doi:10.3201/eid2313.170544 · Cited by 155

Solvent tolerance in bacteria: role of efflux pumps and cross-resistance with antibiotics

Fernandes, P. C. D. B. (2003) · International Journal of Antimicrobial Agents · doi:10.1016/s0924-8579(03)00209-7 · Cited by 148

Resistance of Bacteria to Biocides

Maillard, J. (2018) · Microbiology Spectrum · doi:10.1128/microbiolspec.arba-0006-2017 · Cited by 147

Antibacterial agents in clinical development: an analysis of the antibacterial clinical development pipeline, including tuberculosis

Moja, L. (2017) · Cited by 139

Abusive use of antibiotics in poultry farming in Cameroon and the public health implications

Wadoum, R. E. G., Zambou, N. F., Anyangwe, F. F., Njimou, J. R., Coman, M. M., Verdenelli, M. C., Cecchini, C., Silvi, S., Orpianesi, C., Cresci, A., et al. (2016) · British Poultry Science · doi:10.1080/00071668.2016.1180668 · Cited by 130

Lateral genetic transfer: open issues

Ragan, M. A., & Beiko, R. G. (2009) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2009.0031 · Cited by 114

Prevalence of virulence and antimicrobial resistance genes in Salmonella spp. isolated from commercial chickens and human clinical isolates from South Africa and Brazil

Zishiri, O. T., Mkhize, N., & Mukaratirwa, S. (2016) · Onderstepoort Journal of Veterinary Research · doi:10.4102/ojvr.v83i1.1067 · Cited by 109

Burden of antimicrobial resistance in an era of decreasing susceptibility

Tillotson, G., & Zinner, S. H. (2017) · Expert Review of Anti-infective Therapy · doi:10.1080/14787210.2017.1337508 · Cited by 101

Screening of quinolone antibiotic residues in chicken meat and beef sold in the markets of Ankara, Turkey

Demirhan, B. E., Kaynak‐Onurdag, F., Demirhan, B., Özgen, S., Öktem, A. B., & Abbasoğlu, U. (2013) · Poultry Science · doi:10.3382/ps.2013-03072 · Cited by 98

Environmental Vibrio spp., isolated in Mozambique, contain a polymorphic group of integrative conjugative elements and class 1 integrons

Taviani, E., Ceccarelli, D., Lazaro, N., Bani, S., Cappuccinelli, P., Colwell, R. R., & Colombo, M. M. (2008) · FEMS Microbiology Ecology · doi:10.1111/j.1574-6941.2008.00455.x · Cited by 97

Abundance of antibiotic resistance genes and their association with bacterial communities in activated sludge of wastewater treatment plants: Geographical distribution and network analysis

Zhang, H., He, H., Chen, S., Huang, T., Lu, K., Zhang, Z., Wang, R., Zhang, X., & Li, H. (2019) · Journal of Environmental Sciences · doi:10.1016/j.jes.2019.02.023 · Cited by 97

Epidemiological Investigation and Antimicrobial Resistance Profiles of Salmonella Isolated From Breeder Chicken Hatcheries in Henan, China

Xu, Y., Zhou, X., Jiang, Z., Qi, Y., Ed‐Dra, A., & Yue, M. (2020) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2020.00497 · Cited by 88

FDA-CDC Antimicrobial Resistance Isolate Bank: a Publicly Available Resource To Support Research, Development, and Regulatory Requirements

Lutgring, J. D., Machado, M.-J., Benahmed, F. H., Conville, P. S., Shawar, R. M., Patel, J. B., & Brown, A. C. (2017) · Journal of Clinical Microbiology · doi:10.1128/jcm.01415-17 · Cited by 86

Oxytetracycline residues in edible tissues of cattle slaughtered in Akure, Nigeria

Olatoye, I., & Ehinmowo, A. (2011) · Nigerian Veterinary Journal · doi:10.4314/nvj.v31i2.68952 · Cited by 84

Antibiotic Resistance in an Indian Rural Community: A ‘One-Health’ Observational Study on Commensal Coliform from Humans, Animals, and Water

Purohit, M. R., Chandran, S. P., Shah, H., Diwan, V., Tamhankar, A. J., & Lundborg, C. S. (2017) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph14040386 · Cited by 83

High prevalence and molecular characteristics of multidrug-resistant Salmonella in pigs, pork and humans in Thailand and Laos provinces

Sinwat, N., Angkititrakul, S., Coulson, K. F., PILAPIL-AMANTE, F. M. I. R., Meunsene, D., & Chuanchuen, R. (2016) · Journal of Medical Microbiology · doi:10.1099/jmm.0.000339 · Cited by 82

Identification of extended-spectrum -lactamase and quinolone resistance genes in Escherichia coli isolated from hospital wastewater from central India

Diwan, V., Chandran, S. P., Tamhankar, A. J., Lundborg, C. S., & Macaden, R. (2012) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkr564 · Cited by 81

Implementation of global antimicrobial resistance surveillance system (GLASS) in patients with bacteremia

Sirijatuphat, R., Sripanidkulchai, K., Boonyasiri, A., Rattanaumpawan, P., Supapueng, O., Kiratisin, P., & Thamlikitkul, V. (2018) · PLoS ONE · doi:10.1371/journal.pone.0190132 · Cited by 76

Antimicrobial susceptibility of Acinetobacter clinical isolates and emerging antibiogram trends for nosocomial infection management

Sohail, M. L., Rashid, A., Aslam, B., Waseem, M., Shahid, M., Akram, M., Khurshid, M., & Rasool, M. H. (2016) · Revista da Sociedade Brasileira de Medicina Tropical · doi:10.1590/0037-8682-0111-2016 · Cited by 74

Hospital sewage water: a reservoir for variants of New Delhi metallo-β-lactamase (NDM)- and extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae

Parvez, S., & Khan, A. U. (2017) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2017.08.032 · Cited by 74

Antimicrobial-ResistantEscherichia colifrom Environmental Waters in Northern Colorado

Haberecht, H. B., Nealon, N. J., Gilliland, J. R., Holder, A., Runyan, C., Oppel, R. C., Ibrahim, H., Mueller, L., Schrupp, F., Vilchez, S., et al. (2019) · Journal of Environmental and Public Health · doi:10.1155/2019/3862949 · Cited by 74

Select antibiotics in leachate from closed and active landfills exceed thresholds for antibiotic resistance development

Chung, S. S., Zheng, J., Burket, S. R., & Brooks, B. W. (2018) · Environment International · doi:10.1016/j.envint.2018.03.014 · Cited by 74

Towards a research agenda for water, sanitation and antimicrobial resistance

Wuijts, S., van den Berg, H., Miller, J. H., Abebe, L., Sobsey, M. D., Andremont, A., Medlicott, K. O., van Passel, M. W. J., & Husman, A. M. D. R. (2017) · Journal of Water and Health · doi:10.2166/wh.2017.124 · Cited by 72

Detection of Extended-Spectrum Beta-Lactamase-ProducingEscherichia coliin Market-Ready Chickens in Zambia

Chishimba, K., Hang’ombe, B. M., Muzandu, K. M., Mshana, S. E., Matee, M. I., Nakajima, C., & Suzuki, Y. (2016) · International Journal of Microbiology · doi:10.1155/2016/5275724 · Cited by 70

An Environmental Science and Engineering Framework for Combating Antimicrobial Resistance

Pruden, A. J., Alcalde, R. E., Alvarez, P. J. J., Ashbolt, N. J., Bischel, H. N., Cápiro, N. L., Crossette, E. M., Frigon, D., Grimes, K. L., Haas, C. N., et al. (2018) · Environmental Engineering Science · doi:10.1089/ees.2017.0520 · Cited by 70

Incidence of tetracycline residues in chicken meat and liver retailed to consumers

Salama, N. A., Abo‐Raya, S. H., Shalaby, A. R., Emam, W. H., & Mehaya, F. M. (2011) · Food Additives and Contaminants Part B · doi:10.1080/19393210.2011.585245 · Cited by 69

Molecular characterization of antimicrobial resistance in Gram-negative bacteria isolated from bovine mastitis in Egypt

Ahmed, A. M., & Shimamoto, T. (2011) · Microbiology and Immunology · doi:10.1111/j.1348-0421.2011.00323.x · Cited by 67

Prevalence of Methicillin-Resistant Staphylococcus aureus and Other Staphylococcus Species in Raw Meat Samples Intended for Human Consumption in Benin City, Nigeria: Implications for Public Health

Igbinosa, E. O., Beshiru, A., Akporehe, L., Oviasogie, F. E., & Igbinosa, O. (2016) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph13100949 · Cited by 66

Antibiotic Resistance in Campylobacter jejuni: Mechanism, Status, and Public Health Significance

Khan, J. A., Abulreesh, H. H., Kumar, R., Samreen, S., & Ahmad, I. (2019) · Springer eBooks · doi:10.1007/978-981-13-9871-1_4 · Cited by 65

Prevalence and Antibiotic Resistance Profiles of Campylobacter jejuni Isolated from Poultry Meat and Related Samples at Retail Shops in Northern India

Khan, J. A., Rathore, R. S., Abulreesh, H. H., Qais, F. A., & Ahmad, I. (2018) · Foodborne Pathogens and Disease · doi:10.1089/fpd.2017.2344 · Cited by 64

Occurrence of several main antibiotic residues in raw milk in 10 provinces of China

Zheng, N., Wang, J., Han, R., Xiao-min, X., Zhen, Y., Qu, X., Sun, P., Li, S., & Yu, Z. (2012) · Food Additives and Contaminants Part B · doi:10.1080/19393210.2012.727189 · Cited by 63

Genomic Diversity, Virulence, and Antimicrobial Resistance ofKlebsiella pneumoniaeStrains from Cows and Humans

Yang, Y., Higgins, C. H., Rehman, I., Galvão, K. N., Brito, I., Bicalho, M. L. S., Song, J., Wang, H., & Bicalho, R. C. (2019) · Applied and Environmental Microbiology · doi:10.1128/aem.02654-18 · Cited by 63

The Risk of Some Veterinary Antimicrobial Agents on Public Health Associated with Antimicrobial Resistance and their Molecular Basis

Hao, H., Sander, P., Zahid, I., Wang, Y., Cheng, G., & Yuan, Z. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.01626 · Cited by 62

Impact of antibiotics on the intestinal microbiota needs to be re-defined to optimize antibiotic usage

Ruppé, É., Burdet, C., Grall, N., LASTOURS, V. D., Lescure, F.-X., Andremont, A., & Armand-Lefèvre, L. (2017) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2017.09.017 · Cited by 60

Epistatic control of intrinsic resistance by virulence genes in Listeria

Scortti, M., Han, L., Álvarez‐Narváez, S., Leclercq, A., Moura, A., Lecuit, M., & Vázquez‐Boland, J. A. (2018) · PLoS Genetics · doi:10.1371/journal.pgen.1007525 · Cited by 58

Phenotypically anchored transcriptome profiling of developmental exposure to the antimicrobial agent, triclosan, reveals hepatotoxicity in embryonic zebrafish

Haggard, D. E., Noyes, P. D., Waters, K. M., & Tanguay, R. L. (2016) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2016.08.013 · Cited by 57

Resistance to Biocides in Listeria monocytogenes Collected in Meat-Processing Environments

Conficoni, D., Losasso, C., Cortini, E., Cesare, A. D., Cibin, V., Giaccone, V., Corno, G., & Ricci, A. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.01627 · Cited by 56

Self-resistance in Streptomyces, with Special Reference to β-Lactam Antibiotics

Ogawara, H. (2016) · Molecules · doi:10.3390/molecules21050605 · Cited by 54

Multiple adaptive routes of Salmonella enterica Typhimurium to biocide and antibiotic exposure

Curião, T., Marchi, E., Grandgirard, D., León‐Sampedro, R., Viti, C., Leib, S. L., Baquero, F., Oggioni, M. R., Martínez, J. L., & Coque, T. M. (2016) · BMC Genomics · doi:10.1186/s12864-016-2778-z · Cited by 54

Antibiotic Resistance in Humans and Animals

Spellberg, B. J., Hansen, G. R., Consulting, H., Kar, A., Cordova, C. D., Price, L. B., & Johnson, J. R. (2016) · NAM Perspectives · doi:10.31478/201606d · Cited by 54

‘Fight Antibiotic Resistance—It’s in Your Hands’: Call From the World Health Organization for 5th May 2017

Pires, D., de Kraker, M. E. A., Tartari, E., Abbas, M., & Pittet, D. (2017) · Clinical Infectious Diseases · doi:10.1093/cid/cix226 · Cited by 51

Multiresistant Bacteria Isolated from Activated Sludge in Austria

Galler, H., Feierl, G., Petternel, C., Reinthaler, F. F., Haas, D., Habib, J., Kittinger, C., Luxner, J., & Zarfel, G. (2018) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph15030479 · Cited by 49

Sulfonamides determination in chicken meat products from Malaysia

Cheong, C., Parvaneh, H., Selamat, J., & Ismail‐Fitry, M. R. (2010) · Universiti Putra Malaysia Institutional Repository (Universiti Putra Malaysia) · Cited by 48

Characterization of mcr-1-Harboring Plasmids from Pan Drug-Resistant Escherichia coli Strains Isolated from Retail Raw Chicken in South Korea

Kim, J., Hwang, B. K., Choi, H., Wang, Y., Choi, S. H., Ryu, S., & Jeon, B. (2019) · Microorganisms · doi:10.3390/microorganisms7090344 · Cited by 48

Antibacterial Drug Discovery to Combat MDR

(2019) · Springer eBooks · doi:10.1007/978-981-13-9871-1 · Cited by 47

Emergence of ciprofloxacin-resistant extended-spectrum β-lactamase-producing enteric bacteria in hospital wastewater and clinical sources

Maheshwari, M., Yaser, N. H., Naz, S., Fatima, M., & Ahmad, I. (2016) · Journal of Global Antimicrobial Resistance · doi:10.1016/j.jgar.2016.01.008 · Cited by 45

Diversity of antibiotic‐resistant Shiga toxin‐producing Escherichia coli serogroups in foodstuffs of animal origin in northern India

Khan, J. A., Rathore, R. S., Abulreesh, H. H., Althubiani, A. S., Khan, S., & Ahmad, I. (2018) · Journal of Food Safety · doi:10.1111/jfs.12566 · Cited by 45

Observational Study of the Prevalence and Antibiotic Resistance of Campylobacter spp. from Different Poultry Production Systems in KwaZulu-Natal, South Africa

Bester, L. A., & Essack, S. Y. (2011) · Journal of Food Protection · doi:10.4315/0362-028x.jfp-11-237 · Cited by 43

Molecular characterization of selected multidrug resistant Pseudomonas from water distribution systems in southwestern Nigeria

Adesoji, A. T., Ogunjobi, A. A., & Olatoye, I. O. (2015) · Annals of Clinical Microbiology and Antimicrobials · doi:10.1186/s12941-015-0102-4 · Cited by 39

Antimicrobial Resistant Genes and Organisms as Environmental Contaminants of Emerging Concern: Addressing Global Public Health Risks

Sanderson, H., Brown, R. S., Hania, P., McAllister, T. A., Majury, A. L., & Liss, S. N. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-813290-6.00007-x · Cited by 39

Biotic ligand modeling approach: Synthesis of the effect of major cations on the toxicity of metals to soil and aquatic organisms

Ardestani, M. M., van Straalen, N. M., & van Gestel, C. A. M. (2015) · Environmental Toxicology and Chemistry · doi:10.1002/etc.3060 · Cited by 35

Genetic characterisation of antimicrobial resistance and virulence genes in Staphylococcus aureus isolated from commercial broiler chickens in the Durban metropolitan area, South Africa

Mkize, N., Zishiri, O. T., & Mukaratirwa, S. (2017) · Journal of the South African Veterinary Association · doi:10.4102/jsava.v88i0.1416 · Cited by 35

Part IV. Human infections and antibiotic resistance.

Crowther-Gibson, P., Govender, N., Lewis, D. A., Bamford, C., Brink, A. J., von Gottberg, A., Klugman, K. P., du Plessis, M., Fali, A., Harris, B. N., et al. (2011) · PubMed · Cited by 34

Management of Emerging Public Health Issues and Risks

(2018) · Elsevier eBooks · doi:10.1016/c2016-0-00995-6 · Cited by 34

Salmonella spp. in Bavarian Liquid Pig Manure: Occurrence and Relevance for the Distribution of Antibiotic Resistance

Hölzel, C. S., & Bauer, J. (2008) · Zoonoses and Public Health · doi:10.1111/j.1863-2378.2007.01102.x · Cited by 32

Prevalence and Characterization of Staphylococcus aureus Strains in the Pork Chain Supply in Chile

Velasco, V., Vergara, J. L., Bonilla, A., Muñoz, J., Mallea, A., Vallejos, D., Quezada-Aguiluz, M., Jorge Campos, P., & Rojas-Garcia, P. P. (2018) · Foodborne Pathogens and Disease · doi:10.1089/fpd.2017.2381 · Cited by 30

Carbapenem and Cephalosporin Resistance among Enterobacteriaceae in Healthcare-Associated Infections, California, USA1

Rizzo, K. R., Horwich-Scholefield, S., & Epson, E. E. (2019) · Emerging infectious diseases · doi:10.3201/eid2507.181938 · Cited by 28

Mechanisms Responsible for Cross Resistance and Multiple Resistance

Hall, L. M., Holtum, J. A. M., & Powles, S. B. (2018) · CRC Press eBooks · doi:10.1201/9781351073189-9 · Cited by 28

Ultrasensitive Electrochemical Biosensor for the Detection of the mecA Gene Sequence in Methicillin Resistant Strains of Staphylococcus aureus Employing Gold Nanoparticles

Liu, M., Xiang, H., Hua, E., Wang, L., Jing, X., Cao, X., Sheng, S., & Xie, G. (2014) · Analytical Letters · doi:10.1080/00032719.2013.845894 · Cited by 26

Antibiotic Resistance Patterns of Staphylococcus aureus Isolates from Retail Foods in Mainland China: A Meta-Analysis

Jia, K., Fang, T., Wang, X., Liu, Y., Sun, W., Wang, Y., Ding, T., Wang, J., Li, C., Xu, D., et al. (2019) · Foodborne Pathogens and Disease · doi:10.1089/fpd.2019.2686 · Cited by 26

Persistence of Antibiotic Residue in Milk under Region of Bihar, India

Anjana, R. K. N. K., & Jayachandran, K. G. M. C. (2017) · International Journal of Current Microbiology and Applied Sciences · doi:10.20546/ijcmas.2017.603.262 · Cited by 25

The Antibiotic Crisis: Can We Reverse 65 Years of Failed Stewardship?

Spellberg, B. J. (2011) · Archives of Internal Medicine · doi:10.1001/archinternmed.2011.26 · Cited by 25

Prevalence of antibiotic resistance and virulence factors encoding genes in clinical Staphylococcus aureus isolates in Saudi Arabia

Abulreesh, H. H., Organji, S. R., Osman, G. E. H., Elbanna, K., Almalki, M. H. K., & Ahmad, I. (2016) · Clinical Epidemiology and Global Health · doi:10.1016/j.cegh.2016.08.004 · Cited by 25

Genotypic Characterization of Methicillin-resistant Staphylococcus aureus Isolated from Pigs and Retail Foods in China.

Wang, W., Liu, F., Baloch, Z., Zhang, C. S., Ma, K., Peng, Z. X., Yan, S. F., Hu, Y., Gan, X., Dong, Y. P., et al. (2017) · PubMed · doi:10.3967/bes2017.076 · Cited by 24

Stable oligonucleotide-functionalized gold nanosensors for environmental biocontaminant monitoring

Riquelme, M. V., Leng, W., Carzolio, M., Pruden, A. J., & Vikesland, P. J. (2017) · Journal of Environmental Sciences · doi:10.1016/j.jes.2017.08.005 · Cited by 22

Methicillin Resistant Staphylococcus aureus and Extended Spectrum Beta-lactamase Producing Enterobacteriaceae: A Therapeutic Challenge in the 21st Century

Donkor, E. S., & Codjoe, F. S. (2019) · The Open Microbiology Journal · doi:10.2174/1874285801913010094 · Cited by 22

The effect of organic solvents on the viability and morphofunctional properties of rhodococcus

Korshunova, I. O., Pistsova, O. N., Kuyukina, M. S., & Ившина, И. Б. (2015) · Applied Biochemistry and Microbiology · doi:10.1134/s0003683816010075 · Cited by 22

Filling the map for antimicrobial resistance in sub-Saharan Africa: ampicillin-resistant Enterococcus from non-clinical sources in Angola: Table 1.

Martins, E., Novais, C., Freitas, A. R., Dias, A. R., Ribeiro, T. G., Antunes, P., & Peixe, L. M. S. V. (2015) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkv172 · Cited by 19

Evaluation of Antibiotic Resistant Gene in Abattoir Environment

Igbinosa, E. O., & Obuekwe, I. S. (2014) · Journal of applied science and environmental management · doi:10.4314/jasem.v18i2.3 · Cited by 18

Chapter 6. Presence, Fate and Risks of Pharmaceuticals in the Environment

Kümmerer, K. (2016) · RSC green chemistry series · doi:10.1039/9781782625940-00063 · Cited by 18

Modeling the effect of antibiotic exposure on the transmission of methicillin-resistant Staphylococcus aureus in hospitals with environmental contamination

Huang, Q., Horn, M. A., & Ruan, S. (2019) · Mathematical Biosciences & Engineering · doi:10.3934/mbe.2019181 · Cited by 17

Mechanisms of Horizontal Gene Transfer and DNA Recombination

Blakely, G. W. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-397169-2.00015-9 · Cited by 16

Prevalence, Serovars, and Antimicrobial Resistance of Salmonella in Cecal Samples of Chickens Slaughtered in Pluck Shops in Trinidad

Kumar, N., Mohan, K., Georges, K. C., Dziva, F., & Adesiyun, A. A. (2019) · Journal of Food Protection · doi:10.4315/0362-028x.jfp-18-553 · Cited by 16

Detection of Some Antibiotics Residues in Chicken Meat and Chicken Luncheon

Ahmed, A. A. E., & Gareib, M. (2016) · Egyptian Journal of Chemistry and Environmental Health · doi:10.21608/ejceh.2016.254334 · Cited by 12

Antimicrobial resistance and the activities of the Codex Alimentarius Commission

Bruno, A., & Carolissen-Mackay, V. (2012) · Scientific and Technical Review (World Organisation for Animal Health) · doi:10.20506/rst.31.1.2122 · Cited by 7

Herbicide resistance in plants: biology and biochemistry

Gressel, J. (1997) · Agriculture Ecosystems & Environment · doi:10.1016/s0167-8809(97)82695-3 · Cited by 7

Molecular Characterization of Salmonella spp. from Cattle and Chicken Farms in Uganda

Ball, T. A., Fedorka–Cray, P. J., Horovitz, J. L., & Thakur, S. (2018) · Online Journal of Public Health Informatics · doi:10.5210/ojphi.v10i1.8934 · Cited by 7

Genotypic Characterization of Methicillin-resistant Staphylococcus aureus Isolated from Pigs and Retail Foods in China

Wang, Nie, W., Liu, Feng, Zulqarnain, Baloch, Zhang, Cun, Shan, S., Ma, et al. (2017) · 生物医学与环境科学：英文版 · Cited by 5

Detection of potential AcrAB-TolC multidrug efflux pump inhibitor in calyces extract of Hibiscus sabdariffa

Al‐Karablieh, N., Abu-Qatouseh, L., & Aburjai, T. A. (2017) · Journal of Intercultural Ethnopharmacology · doi:10.5455/jice.20170917062504 · Cited by 2

Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis with forecasts to 2050

Naghavi, M., Vollset, S. E., Ikuta, K. S., Swetschinski, L. R., Gray, A. P., Wool, E. E., Robles Aguilar, G., Mestrovic, T., Smith, G., Han, C., et al. (2024) · The Lancet · doi:10.1016/s0140-6736(24)01867-1 · Cited by 3,791

Antimicrobial Resistance: A Growing Serious Threat for Global Public Health

Salam, M. A., Al-Amin, M. Y., Salam, M. T., Pawar, J. S., Akhter, N., Rabaan, A. A., & Alqumber, M. A. A. (2023) · Healthcare · doi:10.3390/healthcare11131946 · Cited by 2,622

Origin of Antibiotics and Antibiotic Resistance, and Their Impacts on Drug Development: A Narrative Review

Muteeb, G., Rehman, M. T., Shahwan, M. J., & Aatif, M. (2023) · Pharmaceuticals · doi:10.3390/ph16111615 · Cited by 1,416

Potential Causes of Spread of Antimicrobial Resistance and Preventive Measures in One Health Perspective-A Review

Endale, H., Mathewos, M., & Abdeta, D. (2023) · Infection and Drug Resistance · doi:10.2147/idr.s428837 · Cited by 348

An Overview of the Recent Advances in Antimicrobial Resistance

Oliveira, M. T. D. S., Antunes, W., MOTA, S. R. F., Madureira-Carvalho, Á., Dinis‐Oliveira, R. J., & da Silva, D. D. (2024) · Microorganisms · doi:10.3390/microorganisms12091920 · Cited by 349

Antimicrobial Resistance in the Environment: Review of the Selected Resistance Drivers and Public Health Concerns

Puvača, N., Vapa–Tankosić, J., Ignjatijević, S., Carić, M., & Prodanović, R. V. (2022) · Journal of Agronomy Technology and Engineering Management (JATEM) · doi:10.55817/cscq3326 · Cited by 29

Environmental Antibiotic Resistance: Recent Trends, Scope, and Relevance

Sharda, N., Kumar, D., Thakur, R., Sharma, A. K., Sankhyan, S., & Kumar, A. (2023) · Water Air & Soil Pollution · doi:10.1007/s11270-023-06695-w · Cited by 15

Antimicrobial Resistance in the Environment and Their Impact

Priya, N. S., Thenmozhi, R., Steffi, P. F., & Thirumalaiyammal, B. (2024) · CRC Press eBooks · doi:10.1201/9781003268925-8

The Role of the Environment (Water, Air, Soil) in the Emergence and Dissemination of Antimicrobial Resistance: A One Health Perspective

Sassi, A., Basher, N. S., Kirat, H., Meradji, S., Ibrahim, N. A., Idres, T., & Touati, A. (2025) · Antibiotics · doi:10.3390/antibiotics14080764 · Cited by 110

Environment and AMR

Bhatia, R. (2026) · Springer eBooks · doi:10.1007/978-981-92-4190-3_8