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Diagnostic accuracy of elastography and magnetic resonance imaging in patients with NAFLD: A systematic review and meta-analysis
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BACKGROUND AND AIMS: Vibration-controlled transient elastography (VCTE), point shear wave elastography (pSWE), 2-dimensional shear wave elastography (2DSWE), magnetic resonance elastography (MRE), and magnetic resonance imaging (MRI) have been proposed as non-invasive tests for patients with non-alcoholic fatty liver disease (NAFLD). This study evaluated their diagnostic accuracy for liver fibrosis and non-alcoholic steatohepatitis (NASH). METHODS: PubMED/MEDLINE, EMBASE and the Cochrane Library were searched for studies examining the diagnostic accuracy of these index tests, against histology as the reference standard, in adult patients with NAFLD. Two authors independently screened and assessed methodological quality of studies and extracted data. Summary estimates of sensitivity, specificity and area under the curve (sAUC) were calculated for fibrosis stages and NASH, using a random effects bivariate logit-normal model. RESULTS: We included 82 studies (14,609 patients). Meta-analysis for diagnosing fibrosis stages was possible in 53 VCTE, 11 MRE, 12 pSWE and 4 2DSWE studies, and for diagnosing NASH in 4 MRE studies. sAUC for diagnosis of significant fibrosis were: 0.83 for VCTE, 0.91 for MRE, 0.86 for pSWE and 0.75 for 2DSWE. sAUC for diagnosis of advanced fibrosis were: 0.85 for VCTE, 0.92 for MRE, 0.89 for pSWE and 0.72 for 2DSWE. sAUC for diagnosis of cirrhosis were: 0.89 for VCTE, 0.90 for MRE, 0.90 for pSWE and 0.88 for 2DSWE. MRE had sAUC of 0.83 for diagnosis of NASH. Three (4%) studies reported intention-to-diagnose analyses and 15 (18%) studies reported diagnostic accuracy against pre-specified cut-offs. CONCLUSIONS: When elastography index tests are acquired successfully, they have acceptable diagnostic accuracy for advanced fibrosis and cirrhosis. The potential clinical impact of these index tests cannot be assessed fully as intention-to-diagnose analyses and validation of pre-specified thresholds are lacking. LAY SUMMARY: Non-invasive tests that measure liver stiffness or use magnetic resonance imaging (MRI) have been suggested as alternatives to liver biopsy for assessing the severity of liver scarring (fibrosis) and fatty inflammation (steatohepatitis) in patients with non-alcoholic fatty liver disease (NAFLD). In this study, we summarise the results of previously published studies on how accurately these non-invasive tests can diagnose liver fibrosis and inflammation, using liver biopsy as the reference. We found that some techniques that measure liver stiffness had a good performance for the diagnosis of severe liver scarring.
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“Several substantial comparative studies have shown that MRE provides at least equal quality in fi brosis staging as ultrasound-based elastography techniques.”
From EASL-EASD-EASO Clinical Practice Guidelines on the management of metabolic dysfunction-associated steatotic liver disease (MASLD). (2024) · cites this paper as [157]
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Cites
QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies
Whiting, P. F., Rutjes, A. W. S., Westwood, M. E., Mallett, S., Deeks, J. J., Reitsma, J. B., Leeflang, M. M. G., Sterne, J. A. C., Bossuyt, P. M. M., & the QUADAS-2 Group* (2011) · Annals of Internal Medicine · doi:10.7326/0003-4819-155-8-201110180-00009 · Cited by 14,199
Self-citationDesign and validation of a histological scoring system for nonalcoholic fatty liver disease†
Kleiner, D. E., Brunt, E. M., Van Natta, M., Behling, C., Contos, M. J., Cummings, O. W., Ferrell, L. D., Liu, Y., Torbenson, M. S., Unalp‐Arida, A., et al. (2005) · Hepatology · doi:10.1002/hep.20701 · Cited by 10,791
Younossi, Z. M., Koenig, A. B., Abdelatif, D., Fazel, Y., Henry, L., & Wymer, M. (2016) · Hepatology · doi:10.1002/hep.28431 · Cited by 10,781
EASL–EASD–EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease
(2016) · Journal of Hepatology · doi:10.1016/j.jhep.2015.11.004 · Cited by 4,836
Angulo, P., Kleiner, D. E., Dam-Larsen, S., Adams, L. A., Bjornsson, E. S., Charatcharoenwitthaya, P., Mills, P. R., Keach, J. C., Lafferty, H. D., Stahler, A., et al. (2015) · Gastroenterology · doi:10.1053/j.gastro.2015.04.043 · Cited by 2,987
Dulai, P. S., Singh, S., Patel, J., Soni, M., Prokop, L. J., Younossi, Z., Sebastiani, G., Ekstedt, M., Hagstrom, H., Nasr, P., et al. (2017) · Hepatology · doi:10.1002/hep.29085 · Cited by 1,965
Self-citationProgression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis
Anstee, Q. M., Targher, G., & Day, C. P. (2013) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2013.41 · Cited by 1,747
Noninvasive assessment of liver disease in patients with nonalcoholic fatty liver disease
Castera, L., Friedrich-Rust, M., & Loomba, R. (2019) · Gastroenterology · doi:10.1053/j.gastro.2018.12.036 · Cited by 1,494
Eddowes, P. J., Sasso, M., Allison, M., Tsochatzis, E. A., Anstee, Q. M., Sheridan, D. A., Guha, I. N., Cobbold, J., Deeks, J. J., Paradis, V., et al. (2019) · Gastroenterology · doi:10.1053/j.gastro.2019.01.042 · Cited by 1,425
Wong, V. W.-S., Vergniol, J., Wong, G. L.-H., Foucher, J., Chan, H. L.-Y., Le Bail, B., Choi, P. C.-L., Kowo, M., Chan, A. W.-H., Merrouche, W., et al. (2010) · Hepatology · doi:10.1002/hep.23312 · Cited by 1,322
Hagström, H., Nasr, P., Ekstedt, M., Hammar, U., Stål, P., Hultcrantz, R., & Kechagias, S. (2017) · Journal of Hepatology · doi:10.1016/j.jhep.2017.07.027 · Cited by 1,067
McPherson, S., Hardy, T., Henderson, E., Burt, A. D., Day, C. P., & Anstee, Q. M. (2014) · Journal of Hepatology · doi:10.1016/j.jhep.2014.11.034 · Cited by 1,059
Xiao, G., Zhu, S., Xiao, X., Yan, L., Yang, J., & Wu, G. (2017) · Hepatology · doi:10.1002/hep.29302 · Cited by 895
Newsome, P. N., Sasso, M., Deeks, J. J., Paredes, A. H., Boursier, J., Chan, W., Yilmaz, Y. N., Czernichow, S., Zheng, M., Wong, V. W., et al. (2020) · The Lancet. Gastroenterology & hepatology · doi:10.1016/s2468-1253(19)30383-8 · Cited by 839
Imajo, K., Kessoku, T., Honda, Y., Tomeno, W., Ogawa, Y., Mawatari, H., Fujita, K., Yoneda, M., Taguri, M., Hyogo, H., et al. (2015) · Gastroenterology · doi:10.1053/j.gastro.2015.11.048 · Cited by 835
Park, C. C., Nguyen, P., Hernandez, C., Bettencourt, R., Ramirez, K., Fortney, L., Hooker, J. C., Sy, E. Z., Savides, M. T., Alquiraish, M. H., et al. (2016) · Gastroenterology · doi:10.1053/j.gastro.2016.10.026 · Cited by 715
Singh, S., Venkatesh, S. K., Wang, Z., Miller, F. H., Motosugi, U., Low, R. N., Hassanein, T., Asbach, P., Godfrey, E. M., Yin, M., et al. (2014) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2014.09.046 · Cited by 549
Cassinotto, C., Boursier, J., de Lédinghen, V., Lebigot, J., Lapuyade, B., Calès, P., Hiriart, J., Michalak, S., Bail, B. L., Cartier, V., et al. (2015) · Hepatology · doi:10.1002/hep.28394 · Cited by 519
Loomba, R. S., Wolfson, T. J., Ang, B., Hooker, J. C., Behling, C. A., Peterson, M. R., Valasek, M. A., Lin, G., Brenner, D. A., Gamst, A. C., et al. (2014) · Hepatology · doi:10.1002/hep.27362 · Cited by 517
Myers, R. P., Pomier–Layrargues, G., Kirsch, R., Pollett, A. F., Duarte‐Rojo, A., Wong, D., Beaton, M. D., Levstik, M. A., Crotty, P., & Elkashab, M. (2011) · Hepatology · doi:10.1002/hep.24624 · Cited by 511
Kwok, R., Choi, K. C., Wong, G. L., Zhang, Y., Chan, H. L.-Y., Luk, A. O. Y., Shu, S. S., Chan, A. W. H., Yeung, M. W., Chan, J. C. N., et al. (2015) · Gut · doi:10.1136/gutjnl-2015-309265 · Cited by 489
Chen, J., Talwalkar, J. A., Yin, M., Glaser, K. J., Sanderson, S. O., & Ehman, R. L. (2011) · Radiology · doi:10.1148/radiol.11101942 · Cited by 434
Yoneda, M., Yoneda, M., Mawatari, H., Fujita, K., Endo, H., Iida, H., Nozaki, Y., Yonemitsu, K., Higurashi, T., Takahashi, H., et al. (2007) · Digestive and Liver Disease · doi:10.1016/j.dld.2007.10.019 · Cited by 426
Boursier, J., Vergniol, J., Guillet, A., Hiriart, J.-B., Lannes, A., Le Bail, B., Michalak, S., Chermak, F., Bertrais, S., Foucher, J., et al. (2016) · Journal of Hepatology · doi:10.1016/j.jhep.2016.04.023 · Cited by 400
Palmeri, M. L., Wang, M. H., Rouze, N. C., Abdelmalek, M. F., Guy, C. D., Moser, B. K., Diehl, A. M., & Nightingale, K. R. (2011) · Journal of Hepatology · doi:10.1016/j.jhep.2010.12.019 · Cited by 348
Liver Stiffness Measurement Using XL Probe in Patients With Nonalcoholic Fatty Liver Disease
Wong, V. W.-S., Vergniol, J., Wong, G. L.-H., Foucher, J., Chan, A. W.-H., Chermak, F., Choi, P. C.-L., Merrouche, W., Chu, S. H.-T., Pesque, S., et al. (2012) · American Journal of Gastroenterology · doi:10.1038/ajg.2012.331 · Cited by 345
Vali, Y., Lee, J., Boursier, J., Spijker, R., Löffler, J., Verheij, J., Brosnan, M. J., Böcskei, Z., Anstee, Q. M., Bossuyt, P. M., et al. (2020) · Journal of Hepatology · doi:10.1016/j.jhep.2020.03.036 · Cited by 302
Anstee, Q. M., Lawitz, E. J., Alkhouri, N., Wong, V. W., Romero‐Gomez, M., Okanoue, T., Trauner, M., Kersey, K., Li, G., Han, L., et al. (2019) · Hepatology · doi:10.1002/hep.30842 · Cited by 277
Harrison, S. A., Ratziu, V., Boursier, J., Francque, S., Bédossa, P., Majd, Z., Cordonnier, G., Sudrik, F. B., Darteil, R., Liebe, R., et al. (2020) · The Lancet. Gastroenterology & hepatology · doi:10.1016/s2468-1253(20)30252-1 · Cited by 270
Gaia, S., Carenzi, S., Barilli, A. L., Bugianesi, E., Smedile, A., Brunello, F., Marzano, A., & Rizzetto, M. (2010) · Journal of Hepatology · doi:10.1016/j.jhep.2010.06.022 · Cited by 264
Petta, S., Maida, M. F., Macaluso, F. S., Marco, V. D., Cammà, C., Cabibi, D., & Craxı̀, A. (2015) · Hepatology · doi:10.1002/hep.27844 · Cited by 239
Advanced Fibrosis in Nonalcoholic Fatty Liver Disease: Noninvasive Assessment with MR Elastography
Kim, D., Kim, W. R., Talwalkar, J. A., Kim, H. J., & Ehman, R. L. (2013) · Radiology · doi:10.1148/radiol.13121193 · Cited by 229
Modelling multiple thresholds in meta-analysis of diagnostic test accuracy studies
Steinhauser, S., Schumacher, M. C., & Rücker, G. (2016) · BMC Medical Research Methodology · doi:10.1186/s12874-016-0196-1 · Cited by 222
Petta, S., Wong, V. W., Cammà, C., Hiriart, J., Wong, G. L., Marra, F., Vergniol, J., Chan, A. W. H., Marco, V. D., Merrouche, W., et al. (2016) · Hepatology · doi:10.1002/hep.28843 · Cited by 213
Loomba, R. S., Cui, J. Y., Wolfson, T. J., Haufe, W. M., Hooker, J. C., Szeverenyi, N. M., Ang, B., Bhatt, A., Wang, K., Aryafar, H., et al. (2016) · The American Journal of Gastroenterology · doi:10.1038/ajg.2016.65 · Cited by 202
Pavlides, M., Banerjee, R., Tunnicliffe, E. M., Kelly, M., Collier, J. D., Wang, L. M., Fleming, K. A., Cobbold, J., Robson, M. D., Neubauer, S., et al. (2016) · Liver International · doi:10.1111/liv.13284 · Cited by 197
Cui, J. Y., Heba, E. R., Hernandez, C., Haufe, W. M., Hooker, J. C., André, M. P., Valasek, M. A., Aryafar, H., Sirlin, C. B., & Loomba, R. S. (2015) · Hepatology · doi:10.1002/hep.28337 · Cited by 191
Wong, V. W., Irlès, M., Wong, G. L., Shili, S., Chan, A. W. H., Merrouche, W., Shu, S. S., Foucher, J., Bail, B. L., Chan, W., et al. (2019) · Gut · doi:10.1136/gutjnl-2018-317334 · Cited by 174
Tapper, E. B., Challies, T. L., Nasser, I. A., Afdhal, N. H., & Lai, M. (2016) · The American Journal of Gastroenterology · doi:10.1038/ajg.2016.49 · Cited by 163
Petta, S., Wong, V. W., Cammà, C., Hiriart, J., Wong, G. L., Vergniol, J., Chan, A. W. H., Marco, V. D., Merrouche, W., Chan, H. L., et al. (2017) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.14219 · Cited by 159
Petta, S., Marco, V. D., Cammà, C., Butera, G., Cabibi, D., & Craxı̀, A. (2011) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2011.04668.x · Cited by 157
Boursier, J., Guillaume, M., Leroy, V., Irlès, M., Roux, M., Lannes, A., Foucher, J., Zuberbuhler, F., Delabaudière, C., Barthelon, J., et al. (2019) · Journal of Hepatology · doi:10.1016/j.jhep.2019.04.020 · Cited by 157
Cui, J. Y., Ang, B., Haufe, W. M., Hernandez, C., Verna, E. C., Sirlin, C. B., & Loomba, R. S. (2015) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.13196 · Cited by 155
Petta, S., Vanni, E., Bugianesi, E., Marco, V. D., Cammà, C., Cabibi, D., Mezzabotta, L., & Craxı̀, A. (2014) · Liver International · doi:10.1111/liv.12584 · Cited by 137
Jiang, W., Huang, S., Teng, H., Wang, P., Wu, M., Zhou, X., & Ran, H. (2018) · BMJ Open · doi:10.1136/bmjopen-2018-021787 · Cited by 135
Performance of unidimensional transient elastography in staging non-alcoholic steatohepatitis.
Lupșor‐Platon, M., Badea, R., Ştefănescu, H., Grigorescu, M. D., Serban, A., Radu, C., Crișan, D., Sparchez, Z. A., Iancu, S., & Maniu, A. (2010) · PubMed · Cited by 118
Kumar, R. K., Rastogi, A., Sharma, M. K., Bhatia, V., Tyagi, P. K., Sharma, P., Garg, H., Kumar, K., Bihari, C., & Sarin, S. K. (2012) · Digestive Diseases and Sciences · doi:10.1007/s10620-012-2306-1 · Cited by 118
Cassinotto, C., Lapuyade, B., Aït-Ali, A., Vergniol, J., Gaye, D., Foucher, J., Bailacq‐Auder, C., Chermak, F., Bail, B. L., & de Lédinghen, V. (2013) · Radiology · doi:10.1148/radiol.13122208 · Cited by 112
Garg, H., Aggarwal, S., Shalimar, S., Yadav, R., Gupta, S. D., Agarwal, L., & Agarwal, S. (2017) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2017.09.005 · Cited by 112
Predictors of advanced fibrosis in non‐cirrhotic non‐alcoholic fatty liver disease in Germany
Labenz, C., Huber, Y., Kalliga, E., Nagel, M., Ruckes, C., Straub, B. K., Galle, P. R., Wörns, M., Anstee, Q. M., Schuppan, D., et al. (2018) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.14976 · Cited by 106
Eddowes, P. J., McDonald, N., Davies, N. P., Semple, S. I. K., Kendall, T. J., Hodson, J. A., Newsome, P. N., Flintham, R., Wesołowski, R., Blake, L., et al. (2017) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.14469 · Cited by 104
Fierbinteanu-Braticevici, C. G., Sporea, I., Panaitescu, E., & Tribus, L. C. (2013) · Ultrasound in Medicine & Biology · doi:10.1016/j.ultrasmedbio.2013.04.019 · Cited by 98
Das, K., Sarkar, R., Ahmed, S. M., Mridha, A. R., Mukherjee, P. S., Das, K., Dhali, G. K., Santra, A. K., & Chowdhury, A. (2011) · Hepatology · doi:10.1002/hep.24694 · Cited by 92
Lee, H. W., Park, S. Y., Kim, S. U., Jang, J. Y., Park, H., Kim, J. K., Lee, C. K., Chon, Y. E., & Han, K. (2016) · PLoS ONE · doi:10.1371/journal.pone.0157358 · Cited by 91
Staufer, K., Halilbasic, E., Spindelboeck, W., Eilenberg, M., Prager, G., Stadlbauer, V., Posch, A., Munda, P., Marculescu, R., Obermayer-Pietsch, B. M., et al. (2019) · United European Gastroenterology Journal · doi:10.1177/2050640619865133 · Cited by 89
Shen, F., Zheng, R.-D., Shi, J., Mi, Y., Chen, G., Hu, X., Liu, Y., Wang, X., Pan, Q., Chen, G., et al. (2015) · Liver International · doi:10.1111/liv.12809 · Cited by 88
Naveau, S., Lamouri, K., Pourcher, G., Njiké‐Nakseu, M., Ferretti, S., Courie, R., Tranchart, H., Ghinoiu, M., Balian, A., Prevot, S., et al. (2014) · Obesity Surgery · doi:10.1007/s11695-014-1235-9 · Cited by 88
Oeda, S., Takahashi, H., Imajo, K., Seko, Y., Ogawa, Y., Moriguchi, M., Yoneda, M., Anzai, K., Aishima, S., Kage, M., et al. (2019) · Journal of Gastroenterology · doi:10.1007/s00535-019-01635-0 · Cited by 82
Chan, W., Mustapha, N. R. N., Wong, G. L., Wong, V. W., & Mahadeva, S. (2016) · United European Gastroenterology Journal · doi:10.1177/2050640616646528 · Cited by 79
Testing for publication bias in diagnostic meta‐analysis: a simulation study
Bürkner, P., & Doebler, P. (2014) · Statistics in Medicine · doi:10.1002/sim.6177 · Cited by 72
Joo, S. K., Kim, W. K., Kim, D., Kim, J. H., Oh, S., Lee, K. L., Chang, M. S., Jung, Y. J., So, Y. H., Lee, M. S., et al. (2017) · Liver International · doi:10.1111/liv.13549 · Cited by 67
mada: Meta-Analysis of Diagnostic Accuracy
Doebler, P. (2012) · doi:10.32614/cran.package.mada · Cited by 67
Karlas, T., Dietrich, A., Peter, V., Wittekind, C., Lichtinghagen, R., Garnov, N., Linder, N., Schaudinn, A., Busse, H., Prettin, C., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0141649 · Cited by 64
Lee, M. S., Bae, J. M., Joo, S. K., Woo, H., Lee, D. H., Jung, Y. J., Kim, B. G., Lee, K. L., & Kim, W. K. (2017) · PLoS ONE · doi:10.1371/journal.pone.0188321 · Cited by 64
Chan, W., Mustapha, N. R. N., & Mahadeva, S. (2014) · Hepatology International · doi:10.1007/s12072-014-9596-7 · Cited by 59
Costa‐Silva, L., Ferolla, S. M., Lima, A. S., Vidigal, P. V. T., & Ferrari, T. C. A. (2017) · European Journal of Radiology · doi:10.1016/j.ejrad.2017.11.003 · Cited by 58
Loong, T. C., Wei, J. L., Leung, J. C., Wong, G. L., Shu, S. S., Chim, A. M., Chan, A. W. H., Choi, P. C., Tse, Y., Chan, H. L., et al. (2016) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.13671 · Cited by 57
Aykut, U. E., Akyüz, Ü., Yeşıl, A., Eren, F., Gerin, F., Ergelen, R., Çelikel, Ç., & Yilmaz, Y. N. (2014) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365521.2014.958099 · Cited by 52
Takeuchi, H., Sugimoto, K., Oshiro, H., Iwatsuka, K., Kono, S., Yoshimasu, Y., Kasai, Y., Furuichi, Y., Sakamaki, K., & Itoi, T. (2017) · Journal of Medical Ultrasonics · doi:10.1007/s10396-017-0840-3 · Cited by 52
Liang, Y., & Li, D. (2020) · BMC Gastroenterology · doi:10.1186/s12876-020-01234-x · Cited by 49
Dennis, A., Mouchti, S., Kelly, M., Fallowfield, J. A., Hirschfield, G. M., Pavlides, M., & Banerjee, R. (2020) · Scientific Reports · doi:10.1038/s41598-020-71995-8 · Cited by 49
Ziol, M., Kettaneh, A., Ganne‐Carrié, N., Barget, N., Tengher-Barna, I., & Beaugrand, M. (2009) · European Journal of Gastroenterology & Hepatology · doi:10.1097/meg.0b013e32832a20f5 · Cited by 47
Imaging biomarkers for steatohepatitis and fibrosis detection in non-alcoholic fatty liver disease
Gallego‐Durán, R., Cerro-Salido, P., Gómez-González, E., Pareja, M. J., Ampuero, J., Rico, M. C., Aznar, R., Vilar‐Gómez, E., Bugianesi, E., Crespo, J., et al. (2016) · Scientific Reports · doi:10.1038/srep31421 · Cited by 47
Inadomi, C., Takahashi, H., Ogawa, Y., Oeda, S., Imajo, K., Kubotsu, Y., Tanaka, K., Kessoku, T., Okada, M., Isoda, H., et al. (2020) · Hepatology Research · doi:10.1111/hepr.13495 · Cited by 47
Parente, D. B., Paiva, F. F., Neto, J. A. O., Machado‐Silva, L., Figueiredo, F. A. F., Lanzoni, V. P., Campos, C. F. F., do Brasil, P. E. A. A., Gomes, M. B., Perez, R. D. M., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0125653 · Cited by 45
Leong, W. L., Lai, L. L., Mustapha, N. R. N., Vijayananthan, A., Rahmat, K., Mahadeva, S., & Chan, W. (2019) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.14782 · Cited by 45
Kim, J. W., Lee, Y., Park, Y. S., Kim, B., Lee, S. Y., Yeon, J. E., & Lee, C. H. (2020) · Scientific Reports · doi:10.1038/s41598-020-59601-3 · Cited by 44
Mahadeva, S., Mahfudz, A. S., Vijayananthan, A., Goh, K., Arumugam, K., & Cheah, P. (2013) · Journal of Digestive Diseases · doi:10.1111/1751-2980.12088 · Cited by 42
Park, C. C., Nguyen, P., Hernandez, C., Bettencourt, R., Ramirez, K., Fortney, L., Hooker, J. C., Sy, E. Z., Alquiraish, M. H., Valasek, M. A., et al. (2017) · Gastroenterology · doi:10.1016/s0016-5085(17)30587-5 · Cited by 42
Naveau, S., Voican, C. S., Lebrun, A., Gaillard, M., Lamouri, K., Njiké‐Nakseu, M., Courie, R., Tranchart, H., Balian, A., Prevot, S., et al. (2017) · European Journal of Gastroenterology & Hepatology · doi:10.1097/meg.0000000000000919 · Cited by 35
Shima, T., Sakai, K., Oya, H., Katayama, T., Mitsumoto, Y., Mizuno, M., Kanbara, Y., & Okanoue, T. (2019) · Journal of Gastroenterology · doi:10.1007/s00535-019-01626-1 · Cited by 35
Attia, D. I., Bantel, H., Lenzen, H., Manns, M. P., Gebel, M., & Potthoff, A. (2016) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.13710 · Cited by 34
Younes, R., Rosso, C., Petta, S., Cucco, M., Marietti, M., Caviglia, G. P., Ciancio, A., Abate, M. L., Cammà, C., Smedile, A., et al. (2017) · Liver International · doi:10.1111/liv.13612 · Cited by 33
Blake, L., Duarte, R. V., & Cummins, C. (2016) · BMJ Open · doi:10.1136/bmjopen-2015-010507 · Cited by 32
Ooi, G., Earnest, A., Kemp, W. W., Burton, P. R., Laurie, C., Majeed, A., Johnson, N. A., McLean, C., Roberts, S. K., & Brown, W. A. (2018) · International Journal of Obesity · doi:10.1038/s41366-018-0007-3 · Cited by 32
Schneider, A., Linde, K., Reitsma, J. B., Steinhauser, S., & Rücker, G. (2017) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2017.09.001 · Cited by 31
Lee, Y., Yoo, Y. J., Jung, Y. K., Kim, J. H., Seo, Y. S., Yim, H. J., Kim, I. H., Lee, S. Y., Kim, B., Kim, J. W., et al. (2020) · Clinical and Translational Gastroenterology · doi:10.14309/ctg.0000000000000157 · Cited by 31
Besutti, G., Valenti, L. V. C., Ligabue, G., Bassi, M. C., Pattacini, P., Guaraldi, G., & Rossi, P. G. (2019) · Liver International · doi:10.1111/liv.14118 · Cited by 30
Rosso, C., Caviglia, G. P., Abate, M. L., Vanni, E., Mezzabotta, L., Touscoz, G. A., Olivero, A., Marengo, A., Rizzetto, M., Bugianesi, E., et al. (2015) · Digestive and Liver Disease · doi:10.1016/j.dld.2015.09.008 · Cited by 29
Okajima, A., Sumida, Y., Taketani, H., Hara, T., Seko, Y., Ishiba, H., Nishimura, T., Umemura, A., Nishikawa, T., Yamaguchi, K., et al. (2016) · Hepatology Research · doi:10.1111/hepr.12793 · Cited by 25
Ozturk, A., Mohammadi, R., Pierce, T. T., Kamarthi, S. V., Dhyani, M., Grajo, J. R., Corey, K. E., Chung, R. T., Bhan, A. K., Chhatwal, J., et al. (2020) · Ultrasound in Medicine & Biology · doi:10.1016/j.ultrasmedbio.2019.12.020 · Cited by 24
Gaia, S., Campion, D., Evangelista, A., Spandre, M., Cosso, L., Brunello, F., Ciccone, G., Bugianesi, E., & Rizzetto, M. (2014) · Liver International · doi:10.1111/liv.12761 · Cited by 23
Value of controlled attenuation parameter in fibrosis prediction in nonalcoholic steatohepatitis
Lee, J. I., Lee, H. W., & Lee, K. S. (2019) · World Journal of Gastroenterology · doi:10.3748/wjg.v25.i33.4959 · Cited by 21
Kao, W., Chang, I., Chen, C., Su, C., Fang, S. U., Tang, J., Chang, C., Chang, Y., & Wang, W. (2020) · Obesity Surgery · doi:10.1007/s11695-019-04192-w · Cited by 21
Assessment of transient elastography in Japanese patients with non‐alcoholic fatty liver disease
Seki, K., Shima, T., Oya, H., Mitsumoto, Y., Mizuno, M., & Okanoue, T. (2016) · Hepatology Research · doi:10.1111/hepr.12829 · Cited by 20
Cardoso, A. C., Cravo, C. M., Calçado, F. L. V., Rezende, G., Campos, C. F. F., de Araújo-Neto, J. M., Luz, R., Soares, J. A. S., Moraes-Coelho, H. S., Leite, N. C., et al. (2019) · European Journal of Gastroenterology & Hepatology · doi:10.1097/meg.0000000000001496 · Cited by 18
Agrawal, S., Hoad, C. L., Francis, S., Guha, I. N., Kaye, P., & Aithal, G. P. (2016) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365521.2016.1233578 · Cited by 17
diagmeta: Meta-Analysis of Diagnostic Accuracy Studies with Several Cutpoints
Rücker, G., Steinhauser, S., Kolampally, S., & Schwarzer, G. (2018) · doi:10.32614/cran.package.diagmeta · Cited by 15
Ergelen, R., Yilmaz, Y. N., Asedov, R., Çelikel, Ç., Akın, H., Buğdaycı, O., Altun, E., & Tüney, D. (2016) · Abdominal Radiology · doi:10.1007/s00261-016-0699-6 · Cited by 12
Medellin, A., Pridham, G., Urbanski, S. J., Jayakumar, S., & Wilson, S. R. (2019) · Ultrasound in Medicine & Biology · doi:10.1016/j.ultrasmedbio.2019.08.003 · Cited by 7
Continuous CAP algorithm: reduced variability in a prospective cohort
Audière, S., Miette, V., Fournier, C., Whitehead, J., Paredes, A. H., Sandrin, L., & Harrison, S. A. (2020) · Journal of Hepatology · doi:10.1016/s0168-8278(20)31354-4 · Cited by 6
Loomba, R. S., Lam, J., Wolfson, T. J., Ang, B., Bhatt, A., Peterson, M. R., Brenner, D. A., & Sirlin, C. B. (2013) · Gastroenterology · doi:10.1016/s0016-5085(13)63756-7 · Cited by 5
Dong, X.-Y. (2013) · Journal of China Clinic Medical Imaging · Cited by 2
Forlano, R., Manousou, P., Okaole, A., Mullish, B. H., Khelifa, M., Giannakeas, N., Tzallas, A., Tsipouras, M., Taylor-Robinson, S. D., Yee, M., et al. (2017) · Spiral (Imperial College London) · doi:10.1002/hep.29501 · Cited by 2
Newsome, P. N., Clet, M., Czernichow, S., Eddowes, P. J., Allison, M., Tsochatzis, E. A., Anstee, Q. M., Sheridan, D. A., Guha, N., Cobbold, J., et al. (2020) · Journal of Hepatology · doi:10.1016/s0168-8278(20)31343-x · Cited by 2
Morrison, M., Spataro, J. S., Claridge, L. C., Puri, P., Hughes, H., Shetty, A., Frey, L. J., Fuchs, M. A., & Syn, W. (2020) · Gastroenterology · doi:10.1016/s0016-5085(20)31279-8 · Cited by 1
Flagged first, then by citations
1 of the 107 references couldn’t be matched to a known paper.
Research works printed but not linked: 4
- Al Juboori, 2018, The utility of liver elastography in evaluation of liver fibrosis in obese patients undergoing bariatric surgery, Hepatology, 68
- Clet, 2018, Expanding the Use of the VCTE XL probe in morbid obese patients: validation of a new automated adaptive measurement depths algorithm in a large UK multicenter cohort, Hepatology, 68
- Hee, 2014, Comparison of NAFLD Fibrosis Score (NFS) and transient elastography (Fibroscan), alone and in combination, as non-invasive methods for the evaluation of fibrosis in non-alcoholic fatty liver disease (NAFLD), J Gastroenterol Hepatol, 29, 76
- Pais, 2011, Validation of a simple algorithm combining serum markers and elastometry for the diagnosis of fibrosis in NAFLD, Hepatology, 54
Cited by
Sorted by citations
Tacke, F., Horn, P., Wai-Sun Wong, V., Ratziu, V., Bugianesi, E., Francque, S., Zelber-Sagi, S., Valenti, L., Roden, M., Schick, F., et al. (2024) · Journal of Hepatology · doi:10.1016/j.jhep.2024.04.031 · Cited by 2,210
Cusi, K., Isaacs, S., Barb, D., Basu, R., Caprio, S., Garvey, W. T., Kashyap, S., Mechanick, J. I., Mouzaki, M., Nadolsky, K., et al. (2022) · Endocrine Practice · doi:10.1016/j.eprac.2022.03.010 · Cited by 1,021
EASL Clinical Practice Guidelines on the management of hepatocellular carcinoma
Sangro, B., Argemi, J., Ronot, M., Paradis, V., Meyer, T., Mazzaferro, V., Jepsen, P., Golfieri, R., Galle, P., Dawson, L., et al. (2025) · Journal of Hepatology · doi:10.1016/j.jhep.2024.08.028 · Cited by 985
Kaplan, D. E., Ripoll, C., Thiele, M. S., Fortune, B. E., Simonetto, D. A., García–Tsao, G., & Bosch, J. (2023) · Hepatology · doi:10.1097/hep.0000000000000647 · Cited by 549
(2024) · Obesity Facts · doi:10.1159/000539371 · Cited by 545
Metadata
- Authors
- Selvaraj, E. A., Mózes, F. E., Jayaswal, A. N. A., Zafarmand, M. H., Vali, Y., Lee, J. A., Levick, C. K., Young, L. A. J., Palaniyappan, N., Liu, C.-H., Aithal, G. P., Romero-Gómez, M., Brosnan, M. J., Tuthill, T. A., Anstee, Q. M., Neubauer, S., Harrison, S. A., Bossuyt, P. M., Pavlides, M., Anstee, Q., Daly, A., Johnson, K., Govaere, O., Cockell, S., Tiniakos, D., Bedossa, P., Oakley, F., Cordell, H., Day, C., Wonders, K., Bossuyt, P., Zafarmand, H., Vali, Y., Lee, J., Ratziu, V., Clement, K., Pais, R., Schuppan, D., Schattenberg, J., Vidal-Puig, T., Vacca, M., Rodrigues-Cuenca, S., Allison, M., Kamzolas, I., Petsalaki, E., Oresic, M., Hyötyläinen, T., McGlinchey, A., Mato, J. M., Millet, O., Dufour, J.-F., Berzigotti, A., Pavlides, M., Harrison, S., Neubauer, S., Cobbold, J., Mozes, F., Akhtar, S., Banerjee, R., Kelly, M., Shumbayawonda, E., Dennis, A., Erpicum, C., Romero-Gómez, M., Gómez-González, E., Ampuero, J., Castell, J., Gallego-Durán, R., Fernández, I., Montero-Vallejo, R., Karsdal, M., Erhardtsen, E., Rasmussen, D., Leeming, D. J., Fisker, M. J., Sinisi, A., Musa, K., Betsou, F., Sandt, E., Tonini, M., Bugianesi, E., Rosso, C., Armandi, A., Marra, F., Gastaldelli, A., Svegliati, G., Boursier, J., Francque, S., Vonghia, L., Ekstedt, M., Kechagias, S., Yki-Jarvinen, H., Luukkonen, P., van Mil, S., Papatheodoridis, G., Cortez-Pinto, H., Valenti, L., Petta, S., Miele, L., Geier, A., Trautwein, C., Aithal, G., Hockings, P., Newsome, P., Wenn, D., Pereira Rodrigues, C. M., Chaumat, P., Hanf, R., Trylesinski, A., Ortiz, P., Duffin, K., Brosnan, J., Tuthill, T., McLeod, E., Ertle, J., Younes, R., Ostroff, R., Alexander, L., Kjær, M. S., Mikkelsen, L. F., Balp, M.-M., Brass, C., Jennings, L., Martic, M., Loeffler, J., Hanauer, G., Shankar, S., Fournier, C., Pepin, K., Ehman, R., Myers, J., Ho, G., Torstenson, R., Myers, R., & Doward, L.
- Affiliations
- University of Oxford (GB)
- Nottingham University Hospitals NHS Trust (GB)
- Pfizer (United States) (US)
- Amsterdam University Medical Centers (NL)
- Instituto de Biomedicina de Sevilla (ES)
- ORCID
- Selvaraj, Emmanuel Anandraj
- Jayaswal, Arjun Narayan Ajmer
- Lee, Jenny A.
- Levick, Christina Kim
- Young, Liam Arnold Joseph
- Palaniyappan, Naaventhan
- Liu, Chang-Hai
- Aithal, Guruprasad Padur
- Tuthill, Theresa A.
- Anstee, Quentin M.
- Daly, Ann
- Johnson, Katherine
- Govaere, Olivier
- Cockell, Simon
- Tiniakos, Dina
- Oakley, Fiona
- Cordell, Heather
- Day, Chris
- Wonders, Kristy
- Ratziu, Vlad
- Pais, Raluca
- Schuppan, Detlef
- Schattenberg, Jörn
- Kamzolas, Ioannis
- Petsalaki, Evangelia
- Hyötyläinen, Tuulia
- Dufour, Jean-François
- Berzigotti, Annalisa
- Cobbold, Jeremy
- Banerjee, Rajarshi
- Kelly, Matt
- Shumbayawonda, Elizabeth
- Dennis, Andrea
- Gómez-González, Emilio
- Ampuero, Javier
- Karsdal, Morten
- Rasmussen, Daniel
- Betsou, Fay
- Bugianesi, Elisabetta
- Rosso, Chiara
- Armandi, Angelo
- Marra, Fabio
- Gastaldelli, Amalia
- Boursier, Jérôme
- Francque, Sven
- Vonghia, Luisa
- Ekstedt, Mattias
- Kechagias, Stergios
- Luukkonen, Panu
- Papatheodoridis, George
- Valenti, Luca
- Petta, Salvatore
- Miele, Luca
- Geier, Andreas
- Trautwein, Christian
- Hockings, Paul
- Newsome, Philip
- Ortiz, Pablo
- Duffin, Kevin
- Ertle, Judith
- Younes, Ramy
- Ostroff, Rachel
- Alexander, Leigh
- Kjær, Mette Skalshøi
- Mikkelsen, Lars Friis
- Balp, Maria-Magdalena
- Jennings, Lori
- Loeffler, Juergen
- Shankar, Sudha
- Fournier, Céline
- Pepin, Kay
- Ehman, Richard
- Ho, Gideon
- Doward, Lynda
- Venue
- Journal of Hepatology
- Publisher
- Elsevier BV
- Published
- 2021-10
- Volume
- 75
- Issue
- 4
- Pages
- 770-785
- ISSN
- 0168-8278 (ISSN-L)
- OpenAlex
- W3161701468
- Cited by
- 376
- References
- 107
- Citations by year
- 2026: 67 · 2025: 84 · 2024: 77 · 2023: 81 · 2022: 52 · 2021: 14
- FWCI
- 8.58
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Hepatology (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Deposito de Investigacion Universidad de Sevilla (University of Seville) (publishedVersion, cc-by-nc-nd)
- Pure Amsterdam UMC (publishedVersion, cc-by)
- University of Birmingham Research Portal (University of Birmingham) (publishedVersion, cc-by-nc-nd)
- Repository@Nottingham (University of Nottingham) (acceptedVersion, other-oa)
- Florence Research (University of Florence) (submittedVersion, cc-by-nc-nd)
- Repository@Nottingham (University of Nottingham) (submittedVersion, cc-by-nc-nd)
- Lirias (KU Leuven) (submittedVersion, cc-by-nc-nd)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- HAL (submittedVersion)
- Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano) (submittedVersion, other-oa)
- DIGITAL.CSIC (Spanish National Research Council (CSIC)) (submittedVersion, cc-by-nc-nd)
- Utrecht University Repository (Utrecht University) (submittedVersion, other-oa)
- Nova Science Publishers (Nova Science Publishers, Inc.) (submittedVersion, other-oa)
- PubliCatt (Università Cattolica del Sacro Cuore) (submittedVersion, cc-by-nc-nd)
- CINECA IRIS Institutional Research Information System (University of Bari Aldo Moro) (submittedVersion, cc-by-nc-nd)
- Newcastle University ePrints (Newcastle Univesity) (cc-by-nc-nd)
- Funders
- European Federation of Pharmaceutical Industries and Associations
- Innovative Medicines Initiative (777377)
- Topics
- Health Sciences › Medicine › Hepatology › Liver Disease Diagnosis and Treatment
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Ultrasound Imaging and Elastography
- Health Sciences › Medicine › Hepatology › Liver Disease and Transplantation
- Keywords
- non-alcoholic fatty liver disease, liver fibrosis, nonalcoholic steatohepatitis, vibration-controlled transient elastography, point shear wave elastography, two-dimensional shear wave elastography, magnetic resonance elastography, magnetic resonance imaging, noninvasive fibrosis assessment, liver cirrhosis, diagnostic accuracy
- MeSH terms
- Adult, Humans, Magnetic Resonance Imaging, ROC Curve, Area Under Curve, Elasticity Imaging Techniques, Non-alcoholic Fatty Liver Disease
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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