The DOI matches its Crossref record; 172 of the 172 references it cites were found in a registry or an index.
EASL Clinical Practice Guidelines on acute-on-chronic liver failure
Open accessAbstract
Acute-on-chronic liver failure (ACLF) which has been recently described (2013), is a severe form of acutely decompensated cirrhosis characterized by the existence of organ system failure(s) and high risk of short-term death. ACLF is caused by an excessive systemic inflammatory response triggered by precipitants that are clinically apparent (e.g., proven microbial infection with sepsis, severe alcohol-related hepatitis) or not. Since the description of ACLF, results of some important studies have suggested that patients with ACLF may benefit from liver transplantation and because of this, should be urgently stabilized for transplantation by receiving appropriate treatment of identified precipitants, and full general management, including support of organ systems in the intensive care unit (ICU). The objective of the present CPGs is to provide recommendations helping to recognize ACLF, make triage decisions (ICU vs. no ICU), identify and manage acute precipitants, identify organ systems that require support or replacement, define potential criteria for futility of intensive care, and identify potential indications for liver transplantation. Based on an in-depth review of the relevant literature we provide recommendations to navigate clinical dilemmas followed by supporting text. The recommendations are graded according to the Oxford Centre for Evidence-Based Medicine system and categorized as 'weak' or 'strong'. We aim to provide the best available evidence to aid the clinical decision-making process in the management of patients with ACLF.
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Cites
Expanding consensus in portal hypertension
de Franchis, R. (2015) · Journal of Hepatology · doi:10.1016/j.jhep.2015.05.022 · Cited by 3,078
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Self-citationBaveno VII – Renewing consensus in portal hypertension
de Franchis, R., Bosch, J., Garcia-Tsao, G., Reiberger, T., Ripoll, C., Abraldes, J. G., Albillos, A., Baiges, A., Bajaj, J., Bañares, R., et al. (2022) · Journal of Hepatology · doi:10.1016/j.jhep.2021.12.022 · Cited by 2,930
Self-citationEASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis
Angeli, P., Bernardi, M., Villanueva, C., Francoz, C., Mookerjee, R. P., Trebicka, J., Krag, A., Laleman, W., & Gines, P. (2018) · Journal of Hepatology · doi:10.1016/j.jhep.2018.03.024 · Cited by 2,905
Self-citationTaylor, B. E., McClave, S. A., Martindale, R. G., Warren, M. M., Johnson, D. R., Braunschweig, C., McCarthy, M. S., Davanos, E., Rice, T. W., Cresci, G. A., et al. (2016) · Critical Care Medicine · doi:10.1097/ccm.0000000000001525 · Cited by 1,476
EASL Clinical Practice Guidelines: autoimmune hepatitis
(2015) · Journal of Hepatology · doi:10.1016/j.jhep.2015.06.030 · Cited by 1,245
Early Use of TIPS in Patients with Cirrhosis and Variceal Bleeding
García-Pagán, J. C., Caca, K., Bureau, C., Laleman, W., Appenrodt, B., Luca, A., Abraldes, J. G., Nevens, F., Vinel, J. P., Mössner, J., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa0910102 · Cited by 1,244
EASL Clinical Practice Guidelines on nutrition in chronic liver disease
Merli, M., Berzigotti, A., Zelber-Sagi, S., Dasarathy, S., Montagnese, S., Genton, L., Plauth, M., & Parés, A. (2019) · Journal of Hepatology · doi:10.1016/j.jhep.2018.06.024 · Cited by 1,130
Self-citationGranulocyte colony-stimulating factor and its receptor
Demetri, G., & Griffin, J. (1991) · Blood · doi:10.1182/blood.v78.11.2791.2791 · Cited by 1,064
Jalan, R., Saliba, F., Pavesi, M., Amoros, A., Moreau, R., Ginès, P., Levesque, E., Durand, F., Angeli, P., Caraceni, P., et al. (2014) · Journal of Hepatology · doi:10.1016/j.jhep.2014.06.012 · Cited by 1,032
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Cited by
EASL Clinical Practice Guidelines on the management of hepatocellular carcinoma
Sangro, B., Argemi, J., Ronot, M., Paradis, V., Meyer, T., Mazzaferro, V., Jepsen, P., Golfieri, R., Galle, P., Dawson, L., et al. (2025) · Journal of Hepatology · doi:10.1016/j.jhep.2024.08.028 · Cited by 985
Cell therapy for end-stage liver disease: Current state and clinical challenge
Zhang, L., Deng, Y., Bai, X., Wei, X., Ren, Y., Chen, S., & Deng, H. (2024) · Chinese Medical Journal · doi:10.1097/cm9.0000000000003332 · Cited by 12
Metadata
- Authors
- Moreau, R., Tonon, M., Krag, A., Angeli, P., Berenguer, M., Berzigotti, A., Fernandez, J., Francoz, C., Gustot, T., Jalan, R., Papp, M., & Trebicka, J.
- Venue
- Journal of Hepatology
- Publisher
- Elsevier BV
- Published
- 2023-08
- Volume
- 79
- Issue
- 2
- Pages
- 461-491
- ISSN
- 0168-8278 (ISSN-L)
- OpenAlex
- W4381885461
- Cited by
- 375
- References
- 172
- FWCI
- 53.08
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Moreau, R., Tonon, M., Krag, A., Angeli, P., Berenguer, M., Berzigotti, A., Fernandez, J., Francoz, C., Gustot, T., Jalan, R., Papp, M., & Trebicka, J. (2023). EASL Clinical Practice Guidelines on acute-on-chronic liver failure. Journal of Hepatology. https://doi.org/10.1016/j.jhep.2023.04.021
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