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Cited by 266

The DOI matches its Crossref record; 139 of the 139 references it cites were found in a registry or an index.

Zika fever and congenital Zika syndrome: An unexpected emerging arboviral disease

Open access
Chan, Jasper F.W., Choi, Garnet K.Y., Yip, Cyril C.Y., Cheng, Vincent C.C., Yuen, Kwok-Yung·2016·Journal of Infection
DOI 10.1016/j.jinf.2016.02.011
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Abstract

Summary Unlike its mosquito-borne relatives, such as dengue, West Nile, and Japanese encephalitis viruses, which can cause severe human diseases, Zika virus (ZIKV) has emerged from obscurity by its association with a suspected “congenital Zika syndrome”, while causing asymptomatic or mild exanthematous febrile infections which are dengue- or rubella-like in infected individuals. Despite having been discovered in Uganda for almost 60 years, <20 human cases were reported before 2007. The massive epidemics in the Pacific islands associated with the ZIKV Asian lineage in 2007 and 2013 were followed by explosive outbreaks in Latin America in 2015. Although increased mosquito breeding associated with the El Niño effect superimposed on global warming is suspected, genetic changes in its RNA virus genome may have led to better adaptation to mosquitoes, other animal reservoirs, and human. We reviewed the epidemiology, clinical manifestation, virology, pathogenesis, laboratory diagnosis, management, and prevention of this emerging infection. Laboratory diagnosis can be confounded by cross-reactivity with other circulating flaviviruses. Besides mosquito bite and transplacental transmission, the risk of other potential routes of transmission by transfusion, transplantation, sexual activity, breastfeeding, respiratory droplet, and animal bite is discussed. Epidemic control requires adequate clearance of mosquito breeding grounds, personal protection against mosquito bite, and hopefully a safe and effective vaccine.

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Metadata

Authors
Chan, J. F. W., Choi, G. K. Y., Yip, C. C. Y., Cheng, V. C. C., & Yuen, K.-Y.
Venue
Journal of Infection
Publisher
Elsevier BV
Published
2016-05
Volume
72
Issue
5
Pages
507-524
ISSN
0163-4453 (ISSN-L)
DOI
10.1016/j.jinf.2016.02.011
OpenAlex
W2290442748
Cited by
266
References
139
FWCI
46.55
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Zika fever and congenital Zika syndrome: An unexpected emerging arboviral disease. https://app.cochat.ai/papers/10.1016/j.jinf.2016.02.011
The paper
Chan, J. F. W., Choi, G. K. Y., Yip, C. C. Y., Cheng, V. C. C., & Yuen, K.-Y. (2016). Zika fever and congenital Zika syndrome: An unexpected emerging arboviral disease. Journal of Infection. https://doi.org/10.1016/j.jinf.2016.02.011

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.