The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Correlation between Clinical and Histologic Pulp Diagnoses
Abstract
Introduction Clinicians routinely face conditions in which they have to decide whether the dental pulp can be saved or not. This study evaluated how reliable the clinical diagnosis of normal pulp/reversible pulpitis (savable pulp) or irreversible pulpitis (nonsavable pulp) is when compared with the histologic diagnosis. Methods The study material consisted of 95 teeth collected consecutively in a general practice over a 5-year period and extracted for reasons not related to this study. Based on clinical criteria, teeth were categorized as having normal pulps, reversible pulpitis, or irreversible pulpitis. The former 2 were grouped together because they represent similar conditions in terms of prognosis. Teeth were processed for histologic and histobacteriologic analyses, and pulps were categorized as healthy, reversibly inflamed, or irreversibly inflamed according to defined criteria. The number of matching clinical/histologic diagnosis was recorded. Results The clinical diagnosis of normal pulp/reversible pulpitis matched the histologic diagnosis in 57 of 59 (96.6%) teeth. Correspondence of the clinical and histologic diagnosis of irreversible pulpitis occurred in 27 of 32 (84.4%) cases. Infection advancing to the pulp tissue was a common finding in teeth with irreversible pulpitis but was never observed in normal/reversibly inflamed pulps. Conclusions Findings using defined criteria for clinical and histologic classification of pulp conditions revealed a good agreement, especially for cases with no disease or reversible disease. This means that the classification of pulp conditions as normal pulps, reversible pulpitis, and irreversible pulpitis has high chances of guiding the correct therapy in the large majority of cases. However, there is still a need for refined and improved means for reliable pulp diagnosis.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Future research should focus on establishing clearer correlations between clinical symptoms and histological status of the pulp, as current evidence shows significant discrepancies between these parameters [25].”
From Consensus‐Based Recommendations on Pulp Therapies in Primary and Permanent Teeth: IAPD Porto Forum (2026) · cites this paper as [25]
Citations
Cites
Clinical signs and symptoms in pulp disease
DUMMER, P. M. H., HICKS, R., & HUWS, D. (1980) · International Endodontic Journal · doi:10.1111/j.1365-2591.1980.tb00834.x · Cited by 282
Flagged first, then by citations
Research works printed but not linked: 15
- Abbott, 2007, A clinical classification of the status of the pulp and the root canal system, Aust Dent J, 52, S17, 10.1111/j.1834-7819.2007.tb00522.x · DOI
- Baume, 1970, Diagnosis of diseases of the pulp, Oral Surg Oral Med Oral Pathol, 29, 102, 10.1016/0030-4220(70)90416-0 · DOI
- Seltzer, 1963, The dynamics of pulp inflammation: correlations between diagnostic data and actual histologic findings in the pulp, Oral Surg Oral Med Oral Pathol, 16, 846, 10.1016/0030-4220(63)90323-2 · DOI
- Garfunkel, 1973, Dental pulp pathosis. Clinicopathologic correlations based on 109 cases, Oral Surg Oral Med Oral Pathol, 35, 110, 10.1016/0030-4220(73)90101-1 · DOI
- Johnson, 1970, Pulpal hyperemia—a correlation of clinical and histologic data from 706 teeth, J Am Dent Assoc, 81, 108, 10.14219/jada.archive.1970.0132 · DOI
- Reeves, 1966, The relationship of bacterial penetration and pulpal pathosis in carious teeth, Oral Surg Oral Med Oral Pathol, 22, 59, 10.1016/0030-4220(66)90143-5 · DOI
- Langeland, 1987, Tissue response to dental caries, Endod Dent Traumatol, 3, 149, 10.1111/j.1600-9657.1987.tb00619.x · DOI
- Ricucci, 2010, Fate of the tissue in lateral canals and apical ramifications in response to pathologic conditions and treatment procedures, J Endod, 36, 1, 10.1016/j.joen.2009.09.038 · DOI
- Levin, 2009, Identify and define all diagnostic terms for pulpal health and disease states, J Endod, 35, 1645, 10.1016/j.joen.2009.09.032 · DOI
- Mejàre, 2012, Diagnosis of the condition of the dental pulp: a systematic review, Int Endod J, 45, 597, 10.1111/j.1365-2591.2012.02016.x · DOI · Paper page
- Taylor, 1966, Modification of the Brown and Brenn Gram stain for the differential staining of gram-positive and gram-negative bacteria in tissue sections, Am J Clin Pathol, 46, 472, 10.1093/ajcp/46.4.472 · DOI
- Ricucci, 2003, Bacterial status in root-filled teeth exposed to the oral environment by loss of restoration and fracture or caries—a histobacteriological study of treated cases, Int Endod J, 36, 787, 10.1046/j.1365-2591.2003.00721.x · DOI
- Barthel, 2000, Pulp capping of carious exposures: treatment outcome after 5 and 10 years: a retrospective study, J Endod, 26, 525, 10.1097/00004770-200009000-00010 · DOI
- Hyman, 1984, The predictive value of endodontic diagnostic tests, Oral Surg Oral Med Oral Pathol, 58, 343, 10.1016/0030-4220(84)90065-3 · DOI
- Lundy, 1969, Correlation of pulpal histopathology and clinical symptoms in human teeth subjected to experimental irritation, Oral Surg Oral Med Oral Pathol, 27, 187, 10.1016/0030-4220(69)90172-8 · DOI
Cited by
Sorted by citations
Items 401–426 of 426
MINIMALLY INVASIVE ENDODONTICS
Mubashir, N., & Shabir, B. (2024) · Indian journal of scientific research · doi:10.32606/ijsr.v14.i2.00019
“Furthermore, endodontically treated teeth without visible radiographic signs of apical periodontitis can still be infected (Molander et al. 1998, Ricucci et al. 2014).”
BackgroundInfluentialLi, C., Luan, L., Lyu, A., Yu, X., Wang, S., Xiao, S., Du, Y. Y., Zhang, L., & Du, Y. Y. (2023) · Journal of materials research/Pratt's guide to venture capital sources · doi:10.1557/s43578-023-01253-w · Cited by 2
“These SCAPs can be utilized in a transformative fashion employing chemotaxis, which serves to lure these cells into Article the canal cavity and induce the regrowth of pulp through induction of differentiation [6–8].”
Ali, A., Maqbool, H. M., Khan, G. I., Abrar, F., Shah, F. A., & Jan, M. Z. (2023) · Journal of Khyber College of Dentistry · doi:10.33279/jkcd.v13i3.446
Prise en charge des lésions carieuses profondes chez l’adulte
Joachim, M.-A. G. D. S., Zanini, M., Decup, F., & Villat, C. (2023) · International Conference on Embedded and Multimedia Computing · doi:10.1016/s1877-7864(23)92602-9
Coşar, M., Demirci, G. K., & Çalışkan, M. K. (2023) · International Endodontic Journal · doi:10.1111/iej.13899
Behandlingar av vital pulpa i tänder med djupa karieslesioner
Fransson, H., Stangvaltaite-Mouhat, L., Croft, K., Bletsa, A., & Bjørndal, L. (2023) · Den norske tannlegeforenings Tidende · doi:10.56373/2023-1-6
“För att skydda den vitala vävnaden finns en inflammationszon av varierande omfattning i den intilliggande koronala pulpan, med-an icke-inflammerad pulpavävnad med normal arkitektur kan ses längre apikalt eller i det kontralaterala pulpahornet vid flerrotiga tänder (figur I och II) [13, 14].”
BackgroundAishwarya, P., Nair, M. G., Shivani, P., & Nath, A. S. (2023) · International Journal of Applied Dental Sciences · doi:10.22271/oral.2023.v9.i1d.1686
“Consequently, the radicular pulp can be preserved following the removal of a pulp that has suffered irreversible damages [7] .”
Boschi, G., Piccinelli, G., Bonfanti, C., & Salgarello, S. (2022) · Minerva dental and oral science · doi:10.23736/s2724-6329.22.04614-9
Baş, A., Çelikel, P., & Simşek-Derelioğlu, S. (2022) · European Annals of Dental Sciences · doi:10.52037/eads.2022.0013
Evaluation of The Success of Mature Molar Pulpotomies Using MTA Versus Biodentine. A Clinical Study
Yousef, M., Refai, A., & Islam, T. (2022) · Al-Azhar Journal of Dental Science · doi:10.21608/ajdsm.2021.86023.1212
Pulpotomie beim bleibenden Zahn – Möglichkeiten und Grenzen
Eggmann, F., Connert, T., & Weiger, R. (2022) · Zahnmedizin up2date · doi:10.1055/a-1886-2653
Kady, D. M. E., Rasharaafat, & Farid, M. (2020) · Indian Journal of Public Health Research & Development · doi:10.37506/ijphrd.v11i4.7458
“This result could interpreted by the selection criteria of case and the possible variation between the clinical sign and symptoms and the histopathological status of the pulp(17) also its may contributed to the increase of ion release in the zinc reinforced glass ionomer which may result higher remineralization of aff…”
BackgroundResultTrigeminal Schwannoma simulating orofacial pain: differential diagnosis and treatment. Case report
Hummig, W., Grossmann, T., & Grossmann, E. (2020) · Brazilian Journal Of Pain · doi:10.5935/2595-0118.20200036
Bjørndal, L. (2019) · Essential Endodontology · doi:10.1002/9781119272014.ch9
Assessment of Two Materials in Pulpotomized Immature Permanent Molars
Abuelniel, G., & Kabel, N. (2019) · Egyptian dental journal · doi:10.21608/edj.2019.73989
“Although a history of pain, and bleeding from the amputation site, amongst other clinical indicators can give a reasonable indication whether there is inflammation present in the radicular pulp, this is not always accurate (23,24).”
BackgroundPulpa: Beurteilung von Vitalität und Sensibilität
Bürklein, S., Sabandal, M., & Dammaschke, T. (2019) · ZWR - Das Deutsche Zahnärzteblatt · doi:10.1055/a-1271-9632
“▪ Den Zustand der Pulpa durch klinische Tests genau zu beurteilen und zwischen gesundem und verändertem Pulpagewebe zu unterscheiden, gestaltet sich häufig schwierig [30].”
BackgroundInfluentialPulpa: Beurteilung von Vitalität und Sensibilität
Bürklein, S., Sabandal, M., & Dammaschke, T. (2019) · Zahnmedizin up2date · doi:10.1055/a-0928-7435
“DEFINITION Sensibilität = nervale Versorgung der Pulpa Vitalität = Versorgung der Pulpa mit Blut und Blutgefäßen (= Durchblutung) Der ideale Pulpatest sollte eine einfache, objektive, standardisierte, reproduzierbare, nicht schmerzhafte, verletzungsfreie, genaue und kostengünstige Methode zur Beurteilung des Zustands…”
BackgroundInfluentialCurrent and Emerging Innovations in Minimally Invasive Caries and Endodontic Treatments
Wolters, W., & van der Sluis, L. V. D. (2018) · Clinical Approaches in Endodontic Regeneration · doi:10.1007/978-3-319-96848-3_1
Current Clinical Practice and Future Translation in Regenerative Endodontics
Simon, S. (2018) · Clinical Approaches in Endodontic Regeneration · doi:10.1007/978-3-319-96848-3_10
A new look at the diagnosis of pulpitis
Burke, T. (2018) · Dental Update · doi:10.12968/denu.2018.45.7.589
Zahnpulpa: Vitalerhaltung bis Regeneration
Widbiller, M., & Galler, K. (2018) · Zahnmedizin up2date · doi:10.1055/s-0043-121604
“Histologische Untersuchungen zeigen, dass die klinischen Entzündungszeichen meist zuverlässig mit dem Grad der Entzündung im Pulpagewebe korrelieren [3].”
Background(2026) · Revista de la Asociación Dental Mexicana · doi:10.35366/122576
Meðferð lífkviku í tönnum með djúpa tannátu
Fransson, H., Stangvaltaite-Mouhat, L., Croft, K., Bletsa, A., & Bjørndal, L. (2023) · Tannlæknablaðið · doi:10.33112/tann.41.1.4
“Þó er nokkuð gott samræmi milli klínískrar skilgreiningar á óafturkræfri kvikubólgu og þess hvort bakteríur eru til staðar í dauðum vef í krónukviku (14).”
Odontalgia Simulating Trigeminal Neuralgia: practical approach based on serial cases
Hummig, W., Kubiak, R. J. F., de Almeida, D. D., Ramina, R., & Michelotto, A. L. D. C. (2022) · JBNC - JORNAL BRASILEIRO DE NEUROCIRURGIA · doi:10.22290/jbnc.2022.330203
Bioceramic Materials for Vital Pulp Therapy
Simon, S. (2020) · Springer eBooks · doi:10.1007/978-3-030-58170-1_3
Metadata
- Authors
- Ricucci, D., Loghin, S., & Siqueira, J. F.
- Affiliations
- Estácio (Brazil) (BR)
- Corresponding author
- Ricucci, Domenico
- Venue
- Journal of Endodontics
- Publisher
- Elsevier BV
- Published
- 2014-12
- Volume
- 40
- Issue
- 12
- Pages
- 1932-1939
- ISSN
- 0099-2399 (ISSN-L)
- OpenAlex
- W2079366348
- Cited by
- 477
- References
- 0
- Citations by year
- 2026: 60 · 2025: 58 · 2024: 77 · 2023: 61 · 2022: 55 · 2021: 43 · 2020: 39 · 2019: 28 · 2018: 18 · 2017: 13 · 2016: 17 · 2015: 7
- FWCI
- 14.63
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Endodontics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Dentistry › Oral Surgery › Endodontics and Root Canal Treatments
- Health Sciences › Dentistry › General Dentistry › Dental materials and restorations
- Health Sciences › Dentistry › General Dentistry › Oral Health Pathology and Treatment
- Keywords
- diagnosis, histopathological diagnosis, pulp diagnosis, reversible pulpitis, irreversible pulpitis, pulpitis, pulp infection, endodontic treatment
- MeSH terms
- Adolescent, Adult, Aged, Bacteria, Composite Resins, Dental Amalgam, Dental Caries, Dental Materials, Dental Pulp, Dental Pulp Necrosis, Dental Pulp Test, Dental Restoration, Permanent, Dentin, Dentin, Secondary, Diagnosis, Differential, Female, Humans, Male, Middle Aged, Odontoblasts, Prognosis, Pulpitis, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review