Hypoxic-Ischemic encephalopathy and therapeutic hypothermia: the hemodynamic perspective
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Emerging evidence highlights that factors such as hypocapnia, hyperoxia, extreme fluctuations in blood pressure and glucose are associated with worse outcomes in neonates with HIE.
“Emerging evidence highlights that factors such as hypocapnia, hyperoxia, extreme fluctuations in blood pressure and glucose are associated with worse outcomes in this population (1, 4–8).”
From Lab values in neonates with hypoxic ischemic encephalopathy over time during and after therapeutic hypothermia (2026) · cites this paper as [8]
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Elias, M., Bliznyuk, N., Yasova Barbeau, D., Sukumar, S., Carlos Roig, J., Rajderkar, D., Sura, L., Wynn, J. L., & Weiss, M. D. (2026) · Frontiers in pediatrics · doi:10.3389/fped.2026.1743749
- Authors
- Giesinger, R. E., Bailey, L. J., Deshpande, P., & McNamara, P. J.
- Affiliations
- University of Toronto (CA)
- Corresponding author
- McNamara, Patrick J.
- Venue
- The Journal of Pediatrics
- Publisher
- Elsevier BV
- Published
- 2017-01
- Volume
- 180
- Pages
- 22-30.e2
- ISSN
- 0022-3476 (ISSN-L)
- OpenAlex
- W2530924370
- Cited by
- 92
- References
- 84
- Citations by year
- 2026: 7 · 2025: 14 · 2024: 3 · 2023: 11 · 2022: 10 · 2021: 13 · 2020: 17 · 2019: 6 · 2018: 6 · 2017: 5
- FWCI
- 6.60
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Pediatrics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Neonatal and fetal brain pathology
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Thermal Regulation in Medicine
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Neonatal Health and Biochemistry
- Keywords
- hypoxic-ischemic encephalopathy, therapeutic hypothermia, perinatal asphyxia, neonatal neuroprotection, hemodynamics, cerebral palsy, neurodevelopmental outcomes, neonatal mortality
- MeSH terms
- Asphyxia Neonatorum, Hemodynamics, Humans, Hypothermia, Induced, Infant, Newborn, Hypoxia-Ischemia, Brain
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