The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Photodegradation of avobenzone: Stabilization effect of antioxidants
Abstract
Avobenzone is one of the most common UVA-filters in sunscreens, and is known to be photounstable. Some of the strategies used to stabilize this filter present some drawbacks like photosensitization reactions. Antioxidants are widely used as cosmetic ingredients that prevent photoageing and complement the photoprotection offered by the UV-filters preventing or reducing photogenerated reactive species. The purpose of this work was to study the effect of antioxidants in the photostabilization of avobenzone. The filter dissolved in dimethyl sulfoxide or incorporated in a sunscreen formulation was irradiated with simulated solar radiation (750 W/m(2)). The tested antioxidants were vitamin C, vitamin E, and ubiquinone. The area under the curve of the absorption spectrum for UVA range and the sun protection factor (SPF) were calculated. Vitamin E (1:2), vitamin C (1:0.5) and ubiquinone (1:0.5) were the more effective concentrations increasing the photostability of avobenzone. In sunscreen formulations, the most effective photostabilizer was ubiquinone which also promoted an increase in SPF. This knowledge is important to improve effectiveness of sunscreen formulation. Antioxidants can be valuable ingredients for sunscreens with a triple activity of filter stabilization, SPF boosting and photoageing prevention.
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“Afonso et al. (2014) reported the stabilising effect of antioxidants, namely vitamin C, vitamin E, and ubiquinone, when used concomitantly in the formulation, which improved the photostability of avobenzone (11) with antioxidant concentrations of 10 µg/mL, 2.5 µg/mL, and 2.5 µg/mL, respectively, as well as the improvement of the SPF value of the formulation with ubiquinone [29].”
From UV Filters: Challenges and Prospects (2022) · cites this paper as [29]
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Cites
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A new substrate to measure sunscreen protection factors throughout the ultraviolet spectrum
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Evaluation of the photostability of different UV filter combinations in a sunscreen
Gaspar, L. R., & Campos, P. M. B. G. M. (2005) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2005.08.029 · Cited by 214
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Octocrylene, an Emerging Photoallergen
Avenel-Audran, M., Dutartre, H., Goossens, A. E., Jeanmougin, M., Comte, C., Bernier, C., Benkalfate, L., Michel, M. S., Ferrier‐Lebouedec, M., Vigan, M., et al. (2010) · Archives of Dermatology · doi:10.1001/archdermatol.2010.132 · Cited by 136
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Baker, L. A., Marchetti, B., Karsili, T. N. V., Stavros, V. G., & Ashfold, M. N. R. (2017) · Chemical Society Reviews · doi:10.1039/c7cs00102a · Cited by 201
Implementation of phenols recovered from olive mill wastewater as UV booster in cosmetics
Galanakis, C. M., Tsatalas, P., & Galanakis, I. M. (2017) · Industrial Crops and Products · doi:10.1016/j.indcrop.2017.09.058 · Cited by 181
Carve, M., Nugegoda, D., Allinson, G., & Shimeta, J. (2020) · Environmental Pollution · doi:10.1016/j.envpol.2020.115894 · Cited by 192
UV Filters: Challenges and Prospects
Jesus, A., Sousa, E., Cruz, M., Cidade, H., Lobo, J., & Almeida, I. (2022) · Pharmaceuticals · doi:10.3390/ph15030263 · Cited by 132
Self-citationThe use of emergent technologies to extract added value compounds from grape by-products
Coelho, M. C., Pereira, R. N., Rodrigues, A. S., Teixeira, J. A., & Pintado, M. (2020) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2020.09.028 · Cited by 99
Metadata
- Authors
- Afonso, S., Horita, K., Sousa e Silva, J. P., Almeida, I. F., Amaral, M. H., Lobão, P. A., Costa, P. C., Miranda, M. S., Esteves da Silva, J. C. G., & Sousa Lobo, J. M.
- Affiliations
- Universidade do Porto (PT)
- Venue
- Journal of Photochemistry and Photobiology B: Biology
- Publisher
- Elsevier BV
- Published
- 2014-11
- Volume
- 140
- Pages
- 36-40
- ISSN
- 1011-1344 (ISSN-L)
- OpenAlex
- W2063185930
- Cited by
- 197
- References
- 28
- Citations by year
- 2026: 20 · 2025: 16 · 2024: 18 · 2023: 22 · 2022: 14 · 2021: 21 · 2020: 26 · 2019: 12 · 2018: 13 · 2017: 13 · 2016: 12 · 2015: 9 · 2014: 1
- FWCI
- 12.76
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Photochemistry and Photobiology B Biology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › melanin and skin pigmentation
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › TiO2 Photocatalysis and Solar Cells
- Keywords
- avobenzone, photodegradation, photostabilization, antioxidants, vitamin C, vitamin E, coenzyme Q10, UVA filters, sunscreen formulation, sun protection factor, reactive oxygen species
- MeSH terms
- Antioxidants, Ascorbic Acid, Chemistry, Pharmaceutical, Dimethyl Sulfoxide, Drug Stability, Photolysis, Propiophenones, Sunscreening Agents, Ubiquinone, Ultraviolet Rays, Vitamin E, Sun Protection Factor
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