Sunscreen Photostability
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EHMC undergoes E-to-Z photoisomerisation after UV exposure at 290-320 nm.
“In 1999, Tarras-Wahlberg et al. verified by high-performance liquid chromatography (HPLC) analysis that samples of 21 previously irradiated with UVR (λ = 290–320 nm) showed the presence of an additional band associated with the Z isomer of the UV filter, confirming the conversion between E and Z isomers after UV exposure (Figure 3) [28,30].”
From UV Filters: Challenges and Prospects (2022) · cites this paper as [28]
UV irradiation can promote keto-enol isomerisation of avobenzone and fragmentation into radicals that can form reactive by-products.
“It was verified that UV irradiation can promote the keto-enol isomerisation of 11 (Figure 2 (1)), and the fragmentation into two radicals (Figure 2 (2)), which after could form a phenacyl and benzoyl radicals that could generate reactive by-products, through reaction with others UV filters or fragments [28,30].”
From UV Filters: Challenges and Prospects (2022) · cites this paper as [28]
Benzophenone and dibenzoylmethane derivatives are possibly the most toxic UV filters due to aromatic ketones not easily recognised by human metabolic enzymes, inducing toxic and allergic reactions, and due to photoisomerisation forming toxic reactive photodegradation products.
“Possibly, the most toxic UV filters are mentioned to be the benzophenone and dibenzoylmethane derivatives due to the presence of aromatic ketones, which are not easily recognised by metabolic enzymes in humans, thus inducing toxic and allergic reactions [18], and also because of the photoisomerisation process leading to the formation of toxic and reactive photodegradation products [28].”
From UV Filters: Challenges and Prospects (2022) · cites this paper as [28]
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NAVIGATING THE CHALLENGES AND CONTROVERSIES IN SUNSCREEN: A REVIEW
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Analysis of UV Filters in Sunscreen Products on the Lithuanian Pharmacy Market
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- Authors
- Bonda, C. A., & Lott, D.
- Corresponding author
- Bonda, Craig A.
- Venue
- Principles and Practice of Photoprotection
- Publisher
- Springer International Publishing
- Published
- 2016
- Pages
- 247-273
- OpenAlex
- W3153812694
- Cited by
- 33
- References
- 34
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 6 · 2023: 5 · 2022: 4 · 2021: 4 · 2020: 1 · 2019: 1 · 2018: 1 · 2017: 2 · 2016: 1 · 2014: 2 · 2012: 1
- FWCI
- 7.96
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- Springer eBooks (publishedVersion)
- Topics
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Physical Sciences › Materials Science › Materials Chemistry › Photochromic and Fluorescence Chemistry
- Physical Sciences › Chemistry › Organic Chemistry › Photopolymerization techniques and applications
- Keywords
- photolability, ultraviolet radiation, UV filters, avobenzone, UVA filters, photostabilizers, photochemistry, photostability testing
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