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Cited by 128Maternal Mental Health During Pregnancy and PostpartumAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesMaternal and Neonatal Healthcare

Validity of depression rating scales during pregnancy and the postpartum period: Impact of trimester and parity

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Ji, Shuang, Long, Qi, Jeffrey Newport, D., Na, Hyeji, Knight, Bettina, Zach, Elizabeth B., Morris, Natalie J., Kutner, Michael +1 more·2011·Journal of Psychiatric Research
DOI 10.1016/j.jpsychires.2010.05.017PMC PMC2945623
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Abstract

The objective of the current study was to delineate the optimal cutpoints for depression rating scales during pregnancy and the postpartum period and to assess the perinatal factors influencing these scores. Women participating in prospective investigations of maternal mental illness were enrolled prior to 28 weeks gestation and followed through 6 months postpartum. At each visit, subjects completed self-rated depression scales--Edinburgh Postnatal Depression Scale (EPDS) and Beck Depression Inventory (BDI) and clinician-rated scales--Hamilton Rating Scale for Depression (HRSD(17) and HRSD(21)). These scores were compared to the SCID Mood Module for the presence of fulfilling diagnostic criteria for a major depressive episode (MDE) during 6 perinatal windows: preconception; first trimester; 2nd trimester; 3rd trimester; early postpartum; and later postpartum. Optimal cutpoints were determined by maximizing the sum of each scale's sensitivity and specificity. Stratified ROC analyses determined the impact of previous pregnancy and comparison of initial to follow-up visits. A total of 534 women encompassing 640 pregnancies and 4025 follow-up visits were included. ROC analysis demonstrated that all 4 scales were highly predictive of MDE. The AUCs ranged from 0.857 to 0.971 and were all highly significant (p < .0001). Optimal cutpoints were higher at initial visits and for multigravidas and demonstrated more variability for the self-rated scales. These data indicate that both clinician-rated and self-rated scales can be effective tools in identifying perinatal episodes of major depression. However, the results also suggest that prior childbirth experiences and the use of scales longitudinally across the perinatal period influence optimal cutpoints.

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  • Previous research conducted a receiver operating characteristic curve (ROC) analysis comparing the EPDS, BDI, and HRSD scores with the SCID Mood Module and showed that these scales were highly predictive of a major depressive episode.

    “Although previous research conducted a receiver operating characteristic curve (ROC) analysis comparing the EPDS, BDI, and HRSD scores with the SCID Mood Module and showed that these scales were highly predictive of a major depressive episode,153”

    From Consequences of maternal postpartum depression: A systematic review of maternal and infant outcomes (2019) · cites this paper as [153]

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Research works printed but not linked: 1

  1. First MB Spitzer RL Gibbon M Williams JBW Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Patient Edition (SCID-IP, 11/2002 Revision) Washington, DC American Psychiatric Press 2002

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Authors
Ji, S., Long, Q., Jeffrey Newport, D., Na, H., Knight, B., Zach, E. B., Morris, N. J., Kutner, M., & Stowe, Z. N.
Affiliations
Emory University (US)
Corresponding author
Long, Qi
ORCID
Venue
Journal of Psychiatric Research
Publisher
Elsevier BV
Published
2011-02
Volume
45
Issue
2
Pages
213-219
ISSN
0022-3956 (ISSN-L)
DOI
10.1016/j.jpsychires.2010.05.017
PMC
PMC2945623
OpenAlex
W2108917431
Cited by
128
References
43
Citations by year
2026: 4 · 2025: 1 · 2024: 4 · 2023: 6 · 2022: 5 · 2021: 12 · 2020: 10 · 2019: 11 · 2018: 8 · 2017: 15 · 2016: 12 · 2015: 12 · 2014: 7 · 2013: 12 · 2012: 5
FWCI
6.28
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of Psychiatric Research (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • School of Medicine, Emory University
  • National Institute of Mental Health (P50MH068036, P50MH077928)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Health Sciences › Health Professions › General Health Professions › Maternal and Neonatal Healthcare
Keywords
perinatal depression, major depressive episode, depression rating scales, Edinburgh Postnatal Depression Scale, Beck Depression Inventory, Hamilton Depression Rating Scale, cut-off values, sensitivity and specificity, pregnancy trimesters, parity, multigravida
MeSH terms
Adult, Depression, Female, Follow-Up Studies, Humans, Pregnancy, Pregnancy Trimesters, Psychiatric Status Rating Scales, Psychometrics, Surveys and Questionnaires, Sensitivity and Specificity, Reproducibility of Results, Postpartum Period

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