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Review on in vivo and in vitro methods evaluation of antioxidant activity

Open access
Alam, Md. Nur, Bristi, Nusrat Jahan, Rafiquzzaman, Md.·2013·Saudi Pharmaceutical Journal

Abstract

A good number of abstracts and research articles (in total 74) published, so far, for evaluating antioxidant activity of various samples of research interest were gone through where 407 methods were come across, which were repeated from 29 different methods. These were classified as in vitro and in vivo methods. And those are described and discussed below in this review article. In the later part of this review article, frequency of in vitro as well as in vivo methods is analyzed with a bar diagram. Solvents are important for extracting antioxidants from natural sources. Frequency of solvents used for extraction is also portrayed and the results are discussed in this article. As per this review there are 19 in vitro methods and 10 in vivo methods that are being used for the evaluation of antioxidant activity of the sample of interest. DPPH method was found to be used mostly for the in vitro antioxidant activity evaluation purpose while LPO was found as mostly used in vivo antioxidant assay. Ethanol was with the highest frequency as solvent for extraction purpose.

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Crossref · 10.1016/j.jsps.2012.05.002

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Metadata

Authors
Alam, M. N., Bristi, N. J., & Rafiquzzaman, M.
Venue
Saudi Pharmaceutical Journal
Published
2013-04
Volume
21
Issue
2
Pages
143-152
ISSN
1319-0164 (ISSN-L)
OpenAlex
W1990064402
Cited by
1,758
References
53
FWCI
17.04
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Review on in vivo and in vitro methods evaluation of antioxidant activity. https://app.cochat.ai/papers/10.1016/j.jsps.2012.05.002
The paper
Alam, M. N., Bristi, N. J., & Rafiquzzaman, M. (2013). Review on in vivo and in vitro methods evaluation of antioxidant activity. Saudi Pharmaceutical Journal. https://doi.org/10.1016/j.jsps.2012.05.002

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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