The DOI matches its Crossref record; 115 of the 115 references it cites were found in a registry or an index.
Factors affecting the development of adverse drug reactions (Review article)
Open accessAbstract
OBJECTIVES: To discuss the effect of certain factors on the occurrence of Adverse Drug Reactions (ADRs). DATA SOURCES: A systematic review of the literature in the period between 1991 and 2012 was made based on PubMed, the Cochrane database of systematic reviews, EMBASE and IDIS. Key words used were: medication error, adverse drug reaction, iatrogenic disease factors, ambulatory care, primary health care, side effects and treatment hazards. SUMMARY: Many factors play a crucial role in the occurrence of ADRs, some of these are patient related, drug related or socially related factors. Age for instance has a very critical impact on the occurrence of ADRs, both very young and very old patients are more vulnerable to these reactions than other age groups. Alcohol intake also has a crucial impact on ADRs. Other factors are gender, race, pregnancy, breast feeding, kidney problems, liver function, drug dose and frequency and many other factors. The effect of these factors on ADRs is well documented in the medical literature. Taking these factors into consideration during medical evaluation enables medical practitioners to choose the best drug regimen. CONCLUSION: Many factors affect the occurrence of ADRs. Some of these factors can be changed like smoking or alcohol intake others cannot be changed like age, presence of other diseases or genetic factors. Understanding the different effects of these factors on ADRs enables healthcare professionals to choose the most appropriate medication for that particular patient. It also helps the healthcare professionals to give the best advice to patients. Pharmacogenomics is the most recent science which emphasizes the genetic predisposition of ADRs. This innovative science provides a new perspective in dealing with the decision making process of drug selection.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Incidence of Adverse Drug Reactions in Hospitalized Patients: A Meta-analysis of Prospective Studies
Lazarou, J., Pomeranz, B. H., & Corey, P. N. (1998) · JAMA · doi:10.1001/jama.279.15.1200 · Cited by 4,807
Leape, L. L., Brennan, T. A., Laird, N., Lawthers, A. G., Localio, A. R., Barnes, B. A., Hebert, L., Newhouse, J. P., Weiler, P. C., & Hiatt, H. (1991) · New England Journal of Medicine · doi:10.1056/nejm199102073240605 · Cited by 3,711
Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients
Pirmohamed, M., James, S., Meakin, S., Green, C., Scott, A. K., Walley, T. J., Farrar, K., Park, B. K., & Breckenridge, A. M. (2004) · BMJ · doi:10.1136/bmj.329.7456.15 · Cited by 3,230
Adverse drug reactions: definitions, diagnosis, and management
Edwards, I. R., & Aronson, J. K. (2000) · The Lancet · doi:10.1016/s0140-6736(00)02799-9 · Cited by 2,979
Medication Errors and Adverse Drug Events in Pediatric Inpatients
Kaushal, R. (2001) · JAMA · doi:10.1001/jama.285.16.2114 · Cited by 1,917
The pharmacological basis of therapeutics
Starr, I. (1941) · American Heart Journal · doi:10.1016/s0002-8703(41)90958-4 · Cited by 1,902
The Incidence and Severity of Adverse Events Affecting Patients after Discharge from the Hospital
Forster, A. J., Murff, H. J., Peterson, J. F., Gandhi, T. K., & Bates, D. W. (2003) · Annals of Internal Medicine · doi:10.7326/0003-4819-138-3-200302040-00007 · Cited by 1,886
Kaufman, D. W., Kelly, J. P., Rosenberg, L., Anderson, T. E., & Mitchell, A. A. (2002) · JAMA · doi:10.1001/jama.287.3.337 · Cited by 1,845
Incidence and Preventability of Adverse Drug Events Among Older Persons in the Ambulatory Setting
Gurwitz, J. H., Field, T. S., Harrold, L. R., Rothschild, J., Debellis, K., Seger, A. C., Cadoret, C., Fish, L. S., Garber, L., Kelleher, M., et al. (2003) · JAMA · doi:10.1001/jama.289.9.1107 · Cited by 1,676
Error, stress, and teamwork in medicine and aviation: cross sectional surveys
Sexton, J. B. (2000) · BMJ · doi:10.1136/bmj.320.7237.745 · Cited by 1,611
Cited by
Lorenzo-Almorós, A., Hang, T., Peiró, C., Soriano-Guillén, L., Egido, J., Tuñón, J., & Lorenzo, Ó. (2019) · Cardiovascular Diabetology · doi:10.1186/s12933-019-0935-9 · Cited by 202
Shukla, A. K., Jhaj, R., Misra, S., Ahmed, S. N., Nanda, M., & Chaudhary, D. (2021) · Journal of Family Medicine and Primary Care · doi:10.4103/jfmpc.jfmpc_831_21 · Cited by 93
Cho, B., Roh, J.-W., Park, J., Jeong, K., Kim, T.-H., Kim, Y. S., Kwon, Y.-S., Cho, C.-H., Park, S. H., & Kim, S. H. (2020) · Reproductive Sciences · doi:10.1007/s43032-019-00094-5 · Cited by 44
Xu, Y., Patel, D. N., Ng, S.-L. P., Tan, S.-H., Toh, D., Poh, J., Lim, A. T., Chan, C.-L., Low, M.-Y., & Koh, H.-L. (2018) · Frontiers in Medicine · doi:10.3389/fmed.2018.00167 · Cited by 22
Agreement Among Different Scales for Causality Assessment in Drug-Induced Liver Injury
Das, S., Behera, S. K., Xavier, A. S., Velupula, S., Dkhar, S. A., & Selvarajan, S. (2018) · Clinical Drug Investigation · doi:10.1007/s40261-017-0601-5 · Cited by 19
Metadata
- Authors
- Alomar, M. J.
- Venue
- Saudi Pharmaceutical Journal
- Published
- 2014-04
- Volume
- 22
- Issue
- 2
- Pages
- 83-94
- ISSN
- 1319-0164 (ISSN-L)
- OpenAlex
- W1991864978
- Cited by
- 484
- References
- 115
- FWCI
- 22.43
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Factors affecting the development of adverse drug reactions (Review article). https://app.cochat.ai/papers/10.1016/j.jsps.2013.02.003
- The paper
- Alomar, M. J. (2014). Factors affecting the development of adverse drug reactions (Review article). Saudi Pharmaceutical Journal. https://doi.org/10.1016/j.jsps.2013.02.003
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
