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Cited by 995

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

TFOS DEWS II Tear Film Report

Open access
Willcox, Mark D.P., Argüeso, Pablo, Georgiev, Georgi A., Holopainen, Juha M., Laurie, Gordon W., Millar, Tom J., Papas, Eric B., Rolland, Jannick P., Schmidt, Tannin A., Stahl, Ulrike, Suarez, Tatiana, Subbaraman, Lakshman N., Uçakhan, Omür Ö., Jones, Lyndon·2017·The Ocular Surface

Abstract

The members of the Tear Film Subcommittee reviewed the role of the tear film in dry eye disease (DED). The Subcommittee reviewed biophysical and biochemical aspects of tears and how these change in DED. Clinically, DED is characterized by loss of tear volume, more rapid breakup of the tear film and increased evaporation of tears from the ocular surface. The tear film is composed of many substances including lipids, proteins, mucins and electrolytes. All of these contribute to the integrity of the tear film but exactly how they interact is still an area of active research. Tear film osmolarity increases in DED. Changes to other components such as proteins and mucins can be used as biomarkers for DED. The Subcommittee recommended areas for future research to advance our understanding of the tear film and how this changes with DED. The final report was written after review by all Subcommittee members and the entire TFOS DEWS II membership.

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Metadata

Authors
Willcox, M. D. P., Argüeso, P., Georgiev, G. A., Holopainen, J. M., Laurie, G. W., Millar, T. J., Papas, E. B., Rolland, J. P., Schmidt, T. A., Stahl, U., Suarez, T., Subbaraman, L. N., Uçakhan, O. Ö., & Jones, L.
Venue
The Ocular Surface
Publisher
Elsevier BV
Published
2017-07
Volume
15
Issue
3
Pages
366-403
ISSN
1542-0124 (ISSN-L)
OpenAlex
W2737642784
Cited by
995
References
1
FWCI
60.56
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: TFOS DEWS II Tear Film Report. https://app.cochat.ai/papers/10.1016/j.jtos.2017.03.006
The paper
Willcox, M. D. P., Argüeso, P., Georgiev, G. A., Holopainen, J. M., Laurie, G. W., Millar, T. J., Papas, E. B., Rolland, J. P., Schmidt, T. A., Stahl, U., Suarez, T., Subbaraman, L. N., Uçakhan, O. Ö., & Jones, L. (2017). TFOS DEWS II Tear Film Report. The Ocular Surface. https://doi.org/10.1016/j.jtos.2017.03.006

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.