The DOI matches its Crossref record.
Purification of a Human Prostate Specific Antigen
Abstract
Rabbit antiserum raised against the crude extract of normal human prostatic tissue contained antibodies to a prostatic tissue-specific antigen as shown by immunoprecipitation techniques. Using this antiserum a prostate antigen was detected in normal, benign hypertrophic, and malignant prostatic tissues, but not in other human tissues. The prostate antigen was purified to homogeneity from prostatic tissues and showed a single protein band on analytical polyacrylamide gel electrophoresis and isoelectric focusing. This report thus presents the first demonstration of the purification of a prostate-specific antigen that does not represent prostatic acid phosphatase.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
A history of prostate cancer treatment.
Denmeade, S. R., & Isaacs, J. T. (2002) · Nature reviews. Cancer · doi:10.1038/nrc801 · Cited by 591
The Promoter of the Prostate-Specific Antigen Gene Contains a Functional Androgen Responsive Element
Riegman, P. H. J., Vlietstra, R. J., van der Korput, J. A. G. M., Brinkmann, A. O., & Trapman, J. (1991) · Molecular Endocrinology · doi:10.1210/mend-5-12-1921 · Cited by 451
Novel diagnostic biomarkers for prostate cancer
Madu, C. O., & Lu, Y. (2010) · Journal of Cancer · doi:10.7150/jca.1.150 · Cited by 261
NONPROSTATIC SOURCES OF PROSTATE-SPECIFIC ANTIGEN
Diamandis, E. P., & Yu, H. (1997) · Urologic Clinics of North America · doi:10.1016/s0094-0143(05)70373-6 · Cited by 172
Proteomic cancer biomarkers from discovery to approval: it’s worth the effort
Li, D., & Chan, D. W. (2014) · Expert Review of Proteomics · doi:10.1586/14789450.2014.897614 · Cited by 54
Metadata
- Authors
- Wang, M. C., Valenzuela, L. A., Murphy, G. P., & Chu, T. M.
- Venue
- Journal of Urology
- Published
- 2017-02
- Volume
- 197
- Issue
- 2S
- Pages
- 159-63
- ISSN
- 0022-5347 (ISSN-L)
- 1527-3792
- OpenAlex
- W2083995483
- Cited by
- 825
- References
- 0
- FWCI
- 13.24
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Purification of a Human Prostate Specific Antigen. https://app.cochat.ai/papers/10.1016/j.juro.2016.10.100
- The paper
- Wang, M. C., Valenzuela, L. A., Murphy, G. P., & Chu, T. M. (2017). Purification of a Human Prostate Specific Antigen. Journal of Urology. https://doi.org/10.1016/j.juro.2016.10.100
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
