Cited by 15Health Systems, Economic Evaluations, Quality of LifeTechnology Assessment and ManagementPharmaceutical Economics and Policy

When Future Change Matters: Modeling Future Price and Diffusion in Health Technology Assessments of Medical Devices

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Grimm, Sabine E., Dixon, Simon, Stevens, John W.·2016·Value in Health

Abstract

Background Health technology assessments (HTAs) that take account of future price changes have been examined in the literature, but the important issue of price reductions that are generated by the reimbursement decision has been ignored.Objectives To explore the impact of future price reductions caused by increasing uptake on HTAs and decision making for medical devices.Methods We demonstrate the use of a two-stage modeling approach to derive estimates of technology price as a consequence of changes in technology uptake over future periods on the basis of existing theory and supported by empirical studies. We explore the impact on cost-effectiveness and expected value of information analysis in an illustrative example on the basis of a technology in development for preterm birth screening.Results The application of our approach to the case study technology generates smaller incremental cost-effectiveness ratios compared with the commonly used single cohort approach. The extent of this reduction in the incremental cost-effectiveness ratio depends on the magnitude of the modeled price reduction, the speed of diffusion, and the length of the assumed technology life horizon. Results of value of information analysis are affected through changes in the expected net benefit calculation, the addition of uncertain parameters, and the diffusion-adjusted estimate of the affected patient population.Conclusions Because modeling future changes in price and uptake has the potential to affect HTA outcomes, modeling techniques that can address such changes should be considered for medical devices that may otherwise be rejected.

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Authors
Grimm, S. E., Dixon, S., & Stevens, J. W.
Affiliations
University of Sheffield (GB)
Corresponding author
Grimm, Sabine E.
Venue
Value in Health
Publisher
Elsevier BV
Published
2016-09
Volume
19
Issue
6
Pages
720-726
ISSN
1098-3015 (ISSN-L)
OpenAlex
W2487141499
Cited by
15
References
29
Citations by year
2026: 1 · 2025: 1 · 2024: 1 · 2021: 1 · 2020: 5 · 2019: 2 · 2018: 4
FWCI
3.89
Type
journal article
Language
en
Open access
Locations
  • Value in Health (publishedVersion)
  • PubMed (publishedVersion)
  • White Rose Research Online (University of Leeds, The University of Sheffield, University of York) (acceptedVersion)
Topics
  • Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
  • Physical Sciences › Engineering › Safety, Risk, Reliability and Quality › Technology Assessment and Management
  • Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Pharmaceutical Economics and Policy
Keywords
health technology assessment, medical devices, technology diffusion, reimbursement decisions, discounts, cost-effectiveness, value of information analysis, preterm birth screening, two-stage model, technology adoption
MeSH terms
Commerce, Cost-Benefit Analysis, Diffusion of Innovation, Equipment and Supplies, Technology Assessment, Biomedical, Drug Costs, Economics, Pharmaceutical, Models, Economic

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