The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
The SLC4 family of bicarbonate transporters
Open accessAbstract
The SLC4 family consists of ten genes (SLC4A1-5; SLC4A7-11). All encode integral membrane proteins with very similar hydropathy plots—consistent with 10 – 14 transmembrane segments. Nine SLC4 members encode proteins that transport HCO3− (or a related species, such as CO3=) across the plasma membrane. Functionally, eight of these proteins fall into two major groups: three Cl-HCO3 exchangers (AE1 – 3) and five Na+-coupled HCO3− transporters (NBCe1, NBCe2, NBCn1, NBCn2, NDCBE). Two of the Na+ - coupled transporters (NBCe1, NBCe2) are electrogenic; the other three Na+-coupled HCO3− transporters and all three AEs are electroneutral. In addition, two other SLC4 members (AE4, SLC4A9 and BTR1, SLC4A11) do not yet have a firmly established function. Most, though not all, SLC4 members are functionally inhibited by 4,4′-diisothiocyanatostilbene-2,2′-disulfonate (DIDS). SLC4 proteins play important roles many modes of acid-base homeostasis: the carriage of CO2 by erythrocytes, the transport of H+ or HCO3− by several epithelia, as well as the regulation of cell volume and intracellular pH.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Strong association of de novo copy number mutations with autism
Sebat, J., Lakshmi, B., Malhotra, D., Troge, J., Lese-Martin, C., Walsh, T., Yamrom, B., Yoon, S., Krasnitz, A., Kendall, J., et al. (2007) · Science · doi:10.1126/science.1138659 · Cited by 2,795
Stoichiometry and Ion Dependencies of the Intracellular-pH-Regulating Mechanism in Squid Giant Axons
Boron, W. F., & Russell, J. M. (1983) · The Journal of general physiology · doi:10.1085/jgp.81.3.373 · Cited by 169
Self-citation
Cited by
Verkhratsky, A., & Nedergaard, M. (2018) · Physiological Reviews · doi:10.1152/physrev.00042.2016 · Cited by 1,678
Physiology of Intestinal Absorption and Secretion
Kiela, P. R., & Ghishan, F. K. (2016) · Best Practice & Research Clinical Gastroenterology · doi:10.1016/j.bpg.2016.02.007 · Cited by 752
Dental Enamel Formation and Implications for Oral Health and Disease
Lacruz, R. S., Habelitz, S., Wright, J. T., & Paine, M. L. (2017) · Physiological Reviews · doi:10.1152/physrev.00030.2016 · Cited by 599
The Cellular Mechanisms of Neuronal Swelling Underlying Cytotoxic Edema
Rungta, R. L., Choi, H. B., Tyson, J. R., Malik, A., Dissing-Olesen, L., Lin, P. J. C., Cain, S. M., Cullis, P. R., Snutch, T. P., & MacVicar, B. A. (2015) · Cell · doi:10.1016/j.cell.2015.03.029 · Cited by 255
Disruption of Slc4a10 augments neuronal excitability and modulates synaptic short-term plasticity
Sinning, A., Liebmann, L., & Hübner, C. A. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00223 · Cited by 32
Metadata
- Authors
- Romero, M. F., Chen, A.-P., Parker, M. D., & Boron, W. F.
- Venue
- Molecular Aspects of Medicine
- Publisher
- Elsevier BV
- Published
- 2013-04
- Volume
- 34
- Issue
- 2-3
- Pages
- 159-182
- ISSN
- 0098-2997 (ISSN-L)
- OpenAlex
- W1983930192
- Cited by
- 326
- References
- 2
- FWCI
- 11.16
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: The SLC4 family of bicarbonate transporters. https://app.cochat.ai/papers/10.1016/j.mam.2012.10.008
- The paper
- Romero, M. F., Chen, A.-P., Parker, M. D., & Boron, W. F. (2013). The SLC4 family of bicarbonate transporters. Molecular Aspects of Medicine. https://doi.org/10.1016/j.mam.2012.10.008
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
