Cited by 190Microplastics and Plastic PollutionEnvironmental Toxicology and EcotoxicologyPharmaceutical and Antibiotic Environmental Impacts

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Assessment of microplastic-sorbed contaminant bioavailability through analysis of biomarker gene expression in larval zebrafish

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Sleight, Victoria A., Bakir, Adil, Thompson, Richard C., Henry, Theodore B.·2017·Marine Pollution Bulletin

DOI 10.1016/j.marpolbul.2016.12.055

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Abstract

Microplastics (MPs) are prevalent in marine ecosystems. Because toxicants (termed here “co-contaminants”) can sorb to MPs, there is potential for MPs to alter co-contaminant bioavailability. Our objective was to demonstrate sorption of two co-contaminants with different physicochemistries [phenanthrene (Phe), log10Kow = 4.57; and 17α-ethinylestradiol (EE2), log10Kow = 3.67] to MPs; and assess whether co-contaminant bioavailability was increased after MP settlement. Bioavailability was indicated by gene expression in larval zebrafish. Both Phe and EE2 sorbed to MPs, which reduced bioavailability by a maximum of 33% and 48% respectively. Sorption occurred, but was not consistent with predictions based on co-contaminant physicochemistry (Phe having higher log10Kow was expected to have higher sorption). Contaminated MPs settled to the bottom of the exposures did not lead to increased bioavailability of Phe or EE2. Phe was 48% more bioavailable than predicted by a linear sorption model, organism-based measurements therefore contribute unique insight into MP co-contaminant bioavailability.

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Microplastics in the marine environment
Andrady, A. L. (2011) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2011.05.030 · Cited by 8,105 · cited 2×
“uPVC was selected as a model polymer because it is reported globally in themarine environment (Andrady, 2011), and because preliminary trials with unplasticized PVC showed that the MPs sank to the bottom.”
Method
Lost at sea: where is all the plastic?
Thompson, R. C., Olsen, Y., Mitchell, R. P., Davis, A., Rowland, S. J., John, A. W. G., McGonigle, D., & Russell, A. E. (2004) · Science · doi:10.1126/science.1094559 · Cited by 7,765 · cited 1×
“A uPVC size of 200 – 250 μ m was selected and provided a high surface area for sorption (Teuten et al., 2009), is comparable with previous work (Bakir et al., 2012) and is representative of small MPs found in the environment (Thompson et al., 2004).”
Result
Accumulation of Microplastic on Shorelines Woldwide: Sources and Sinks
Browne, M. A., Crump, P., Niven, S. J., Teuten, E. L., Tonkin, A., Galloway, T. S., & Thompson, R. C. (2011) · Environmental Science & Technology · doi:10.1021/es201811s · Cited by 4,838
Plastic pollution in the world’s oceans: more than 5 trillion plastic pieces weighing over 250,000 tons afloat at sea
Eriksen, M., Lebreton, L. C. M., Carson, H. S., Thiel, M., Moore, C. J., Borerro, J. C., Galgani, F., Ryan, P. G., & Reisser, J. (2014) · PLoS ONE · doi:10.1371/journal.pone.0111913 · Cited by 4,710 · cited 1×
“Plastic debris is present in numerous shapes and sizes and particles b 5 mm (MPs) in size are reported as the most abundant sizes detected in large-scale assessments of the oceans (Eriksen et al., 2014).”
Background
Incidence of adverse biological effects within ranges of chemical concentrations in marine and estuarine sediments
Long, E. R., MacDonald, D. D., Smith, S. L., & Calder, F. D. (1995) · Environmental Management · doi:10.1007/bf02472006 · Cited by 4,331 · cited 2×
“…of MPs and co-contaminants used in the present study were orders of magnitudes higher than what is found in the environment (Aris et al., 2014; Long et al., 1995; Lusher et al., 2014), and co-contaminant concentrations were deliberately tested at higher than environmentally relevant amounts.”
Background
Transport and release of chemicals from plastics to the environment and to wildlife
Teuten, E. L., Saquing, J. M., Knappe, D. R. U., Barlaz, M. A., Jonsson, S., Björn, A., Rowland, S. J., Thompson, R. C., Galloway, T. S., Yamashita, R., et al. (2009) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2008.0284 · Cited by 2,938
Ingested plastic transfers hazardous chemicals to fish and induces hepatic stress
Rochman, C. M., Hoh, E., Kurobe, T., & Teh, S. J. (2013) · Scientific Reports · doi:10.1038/srep03263 · Cited by 2,169 · cited 3×
“One concern is the potential for MPs to transport harmful pollutants (termed here “ co-contaminants ” ) sorbed from marine environments (Holmes et al., 2012; Mato et al., 2001; Rochman et al., 2013a) into the food chain (Teuten et al., 2007).”
BackgroundMethod
Plastic Resin Pellets as a Transport Medium for Toxic Chemicals in the Marine Environment
Mato, Y., Isobe, T., Takada, H., Kanehiro, H., OHTAKE, C., & Kaminuma, T. (2000) · Environmental Science & Technology · doi:10.1021/es0010498 · Cited by 1,898 · cited 5×
“Phenanthrene [Phe, (log 10 of the octanol:water partition coef ﬁ cient (log 10 K ow ) = 4.57 (Miller et al., 1985)] is a simple three ringed polycyclic aromatic hydrocarbon (PAH) that has been frequently reported as a co-contaminant sorbed to MPs (Mato et al., 2001).”
BackgroundInfluential
Environmental implications of plastic debris in marine settings–entanglement, ingestion, smothering, hangers-on, hitch-hiking and alien invasions
Gregory, M. R. (2009) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2008.0265 · Cited by 1,852 · cited 2×
“Plastic debris is accumulating in the environment on a global scale and the potential for negative effects on ecosystems has become a priority concern for environmental science and policy (Gregory, 2009).”
Background
Pollutants bioavailability and toxicological risk from microplastics to marine mussels
Avio, C. G., Gorbi, S., Milan, M., Benedetti, M., Fattorini, D., d'Errico, G., Pauletto, M., Bargelloni, L., & Regoli, F. (2015) · Environmental Pollution · doi:10.1016/j.envpol.2014.12.021 · Cited by 1,413 · cited 2×
“Recently MPs have been shown to alter the bioavailability of pyrene and PCBs in vertebrates and invertebrates (Avio et al., 2015; Besseling et al., 2013; Oliveira et al., 2013; Rochman et al., 2013b).”
BackgroundMethod

Show all 49 references

Research works printed but not linked: 1

Hansch, 1995, Exploring QSAR: fundamentals and applications in chemistry and biology, Am. Chem. Soc.

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Biotechnology for the Management of Plastics and Microplastics
Murphy, L., & Cleary, J. (2022) · Wiley eBooks · doi:10.1002/9781119762621.ch32 · Cited by 3
Marine plastics: what’s wrong with them?
Bonanno, G. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-822471-7.00001-8 · Cited by 4
Polystyrene may alter the cooperation mechanism of gut microbiota and immune system through co-exposure with DCBQ
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“Contrary to expectations, absorbed phenanthrene and 17α-ethinylestradiol in NPs are no longer bioavailable to fish (Sleight et al., 2017).”
Background
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Fath, A. (2024) · Springer eBooks · doi:10.1007/978-3-662-69844-0_1
Additional file 1 of Toxic effects on enzymatic activity, gene expression and histopathological biomarkers in organisms exposed to microplastics and nanoplastics: a review
Patra, I., Huy, D. T. N., Alsaikhan, F., Opulencia, M. J. C., Van Tuan, P., Nurmatova, K. C., Majdi, A., Shoukat, S., Yasin, G., Margiana, R., et al. (2022) · Figshare · doi:10.6084/m9.figshare.20887262
Additional file 1 of Polystyrene microplastics do not affect juvenile brown trout (Salmo trutta f. fario) or modulate effects of the pesticide methiocarb
Schmieg, H., Huppertsberg, S., Knepper, T. P., Krais, S., Reitter, K., Rezbach, F., Ruhl, A. S., Köhler, H.-R., & Triebskorn, R. (2020) · Figshare · doi:10.6084/m9.figshare.12023601
Micro- and nanoplastics as vectors of aquatic pollutants and genotoxicity: An integrated review across aquatic and mammalian systems with special reference to the scenario in India
Parveen, N., Akbarsha, M. A., & Shadab, G. G. H. A. (2026) · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · doi:10.1016/j.mrgentox.2026.503945
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Ankhi, S. D., & Rahman, M. S. (2026) · Chemosphere · doi:10.1016/j.chemosphere.2026.145005
Toxic effects of MPs and Up Grade® herbicide on the Nile tilapia (Oreochromis niloticus): Oxidative stress, immune responses, and histopathological investigations
Said, R. E. M., Badrey, A. E. A., Hamed, M., Mohamed, I. A. I., Soliman, H. A. M., & Sayed, A. E. H. (2026) · Veterinary Research Communications · doi:10.1007/s11259-026-11398-8
“The bio-availability of co-contaminants may be influenced by MPs since other chemicals might adsorb on them (Sleight et al. 2017).”
A combined hazard to mariculture: Quality and safety impairment associated with intestinal barrier disruption in fish co-exposed to environmentally relevant microplastics and antibiotics
Zhu, L., Cui, C., Bai, Y., Sun, X., Sui, Q., Mazlan, N., & Xia, B. (2026) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2026.143327
Coastal Sustainability Under Development Pressures: A Narrative Review of Degradation Drivers and Governance Responses
Zhang, Y., & Wang, J. (2026) · Journal of Marine Science and Engineering · doi:10.3390/jmse14181738 · Cited by 1
Polluting potential of microplastic and heavy metals in landfill leachate of an urban municipal solid waste disposal site
Sheeba, V. A., Magesh, N. S., & Surendran, U. P. (2026) · Environmental Research · doi:10.1016/j.envres.2026.125799

Authors: Sleight, V. A., Bakir, A., Thompson, R. C., & Henry, T. B.
Affiliations: British Antarctic Survey (GB)
University of Portsmouth (GB)
University of Plymouth (GB)
Corresponding author: Sleight, Victoria A.
ORCID: Sleight, Victoria A.
Bakir, Adil
Thompson, Richard C.
Henry, Theodore B.
Venue: Marine Pollution Bulletin
Publisher: Elsevier BV
Published: 2017-03
Volume: 116
Issue: 1-2
Pages: 291-297
ISSN: 0025-326X (ISSN-L)
DOI: 10.1016/j.marpolbul.2016.12.055
OpenAlex: W2579412410
Cited by: 190
References: 49
Citations by year: 2026: 7 · 2025: 7 · 2024: 13 · 2023: 26 · 2022: 34 · 2021: 32 · 2020: 32 · 2019: 21 · 2018: 15 · 2017: 3
FWCI: 8.74
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
creativecommons.org/licenses/by/4.0/ (vor)
Locations: Marine Pollution Bulletin (publishedVersion, cc-by)
PubMed (publishedVersion)
NERC Open Research Archive (Natural Environment Research Council) (acceptedVersion)
Aberdeen University Research Archive (Aberdeen University) (submittedVersion)
PEARL (University of Plymouth) (submittedVersion)
Funders: Natural Environment Research Council (NE/N006526/1, bas0100036)
Topics: Physical Sciences › Environmental Science › Pollution › Microplastics and Plastic Pollution
Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Environmental Toxicology and Ecotoxicology
Physical Sciences › Environmental Science › Pollution › Pharmaceutical and Antibiotic Environmental Impacts
Keywords: microplastics, co-contaminants, contaminant sorption, bioavailability, phenanthrene, ethinyl estradiol, zebrafish larvae, gene expression biomarkers, octanol-water partition coefficient, marine pollution
MeSH terms: Animals, Biological Availability, Ethinyl Estradiol, Larva, Phenanthrenes, Plastics, Water Pollutants, Chemical, Zebrafish, Biomarkers, Gene Expression

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Assessment of microplastic-sorbed contaminant bioavailability through analysis of biomarker gene expression in larval zebrafish

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