The DOI matches its Crossref record; 83 of the 83 references it cites were found in a registry or an index.
Cortical changes in chronic low back pain: Current state of the art and implications for clinical practice
Open accessAbstract
There is increasing evidence that chronic pain problems are characterised by alterations in brain structure and function. Chronic back pain is no exception. There is a growing sentiment, with accompanying theory, that these brain changes contribute to chronic back pain, although empirical support is lacking. This paper reviews the structural and functional changes of the brain that have been observed in people with chronic back pain. We cast light on the clinical implications of these changes and the possibilities for new treatments but we also advise caution against concluding their efficacy in the absence of solid evidence to this effect.
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Cites
The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity
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Placebo-Induced Changes in fMRI in the Anticipation and Experience of Pain
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Chronic back pain is associated with decreased prefrontal and thalamic gray matter density
Apkarian, A. V., Sosa, Y., Sonty, S., Levy, R. M., Harden, R. N., Parrish, T. B., & Gitelman, D. R. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.2541-04.2004 · Cited by 1,434
Towards a theory of chronic pain
Apkarian, A. V., Baliki, M. N., & Geha, P. Y. (2009) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2008.09.018 · Cited by 876
Beyond Feeling: Chronic Pain Hurts the Brain, Disrupting the Default-Mode Network Dynamics
Baliki, M. N., Geha, P. Y., Apkarian, A. V., & Chialvo, D. R. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.4123-07.2008 · Cited by 853
Evidence of augmented central pain processing in idiopathic chronic low back pain
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Placebo Effects Mediated by Endogenous Opioid Activity on μ-Opioid Receptors
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Extensive reorganization of primary somatosensory cortex in chronic back pain patients
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Cited by
Vlaeyen, J. W. S., Maher, C. G., Wiech, K., Van Zundert, J., Meloto, C. B., Diatchenko, L., Battié, M. C., Goossens, M., Koes, B., & Linton, S. J. (2018) · Nature Reviews Disease Primers · doi:10.1038/s41572-018-0052-1 · Cited by 497
Exercise for chronic musculoskeletal pain: a biopsychosocial approach
Booth, J., Moseley, G. L., Schiltenwolf, M., Cashin, A., Davies, M., & Hübscher, M. (2017) · Musculoskeletal Care · doi:10.1002/msc.1191 · Cited by 381
Self-citationPincus, T., Kent, P., Bronfort, G., Loisel, P., Pransky, G., & Hartvigsen, J. (2013) · Spine · doi:10.1097/brs.0b013e3182a8c5d6 · Cited by 227
Muscle Control and Non-specific Chronic Low Back Pain
Russo, M., Deckers, K., Eldabe, S., Kiesel, K., Gilligan, C., Vieceli, J., & Crosby, P. (2018) · Neuromodulation: Technology at the Neural Interface · doi:10.1111/ner.12738 · Cited by 222
Metadata
- Authors
- Wand, B. M., Parkitny, L., O’Connell, N. E., Luomajoki, H., McAuley, J. H., Thacker, M., & Moseley, G. L.
- Venue
- Manual Therapy
- Publisher
- Elsevier BV
- Published
- 2011-02
- Volume
- 16
- Issue
- 1
- Pages
- 15-20
- ISSN
- 1356-689X (ISSN-L)
- OpenAlex
- W2015073129
- Cited by
- 351
- References
- 83
- FWCI
- 11.68
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Cortical changes in chronic low back pain: Current state of the art and implications for clinical practice. https://app.cochat.ai/papers/10.1016/j.math.2010.06.008
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- Wand, B. M., Parkitny, L., O’Connell, N. E., Luomajoki, H., McAuley, J. H., Thacker, M., & Moseley, G. L. (2011). Cortical changes in chronic low back pain: Current state of the art and implications for clinical practice. Manual Therapy. https://doi.org/10.1016/j.math.2010.06.008
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