The DOI matches its Crossref record; 135 of the 135 references it cites were found in a registry or an index.
Artificial cells: from basic science to applications
Open accessAbstract
Artificial cells have attracted much attention as substitutes for natural cells. There are many different forms of artificial cells with many different definitions. They can be integral biological cell imitators with cell-like structures and exhibit some of the key characteristics of living cells. Alternatively, they can be engineered materials that only mimic some of the properties of cells, such as surface characteristics, shapes, morphology, or a few specific functions. These artificial cells can have applications in many fields from medicine to environment, and may be useful in constructing the theory of the origin of life. However, even the simplest unicellular organisms are extremely complex and synthesis of living artificial cells from inanimate components seems very daunting. Nevertheless, recent progress in the formulation of artificial cells ranging from simple protocells and synthetic cells to cell-mimic particles, suggests that the construction of living life is now not an unrealistic goal. This review aims to provide a comprehensive summary of the latest developments in the construction and application of artificial cells, as well as highlight the current problems, limitations, challenges and opportunities in this field.
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Cites
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Cited by
Mastering Complexity: Towards Bottom-up Construction of Multifunctional Eukaryotic Synthetic Cells
Göpfrich, K., Platzman, I., & Spatz, J. P. (2018) · Trends in Biotechnology · doi:10.1016/j.tibtech.2018.03.008 · Cited by 267
Dissipative self-assembly, competition and inhibition in a self-reproducing protocell model
Post, E. A. J., & Fletcher, S. P. (2020) · Chemical Science · doi:10.1039/d0sc02768e · Cited by 57
Ethical framework on risk governance of synthetic biology
Bohua, L., Yuexin, W., Yakun, O., Kunlan, Z., Huan, L., & Ruipeng, L. (2023) · Journal of Biosafety and Biosecurity · doi:10.1016/j.jobb.2023.03.002 · Cited by 53
From protocells to prototissues: a materials chemistry approach
Gobbo, P. (2020) · Biochemical Society Transactions · doi:10.1042/bst20200310 · Cited by 35
Metadata
- Authors
- Xu, C., Hu, S., & Chen, X.
- Venue
- Materials Today
- Publisher
- Elsevier BV
- Published
- 2016-11
- Volume
- 19
- Issue
- 9
- Pages
- 516-532
- ISSN
- 1369-7021 (ISSN-L)
- OpenAlex
- W2334195094
- Cited by
- 344
- References
- 135
- FWCI
- 11.72
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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