Reducing depression during the menopausal transition with health coaching: Results from the healthy menopausal transition randomised controlled trial
Open accessAbstract
Objective To determine if health coaching (HC) decreases the incidence of depression, reduces the severity of symptoms, and increases quality of life during the menopausal transition (MT).Research design and methods Parallel, single-blinded, randomised controlled trial of 6 sessions of phone-delivered HC compared with usual care. Participants were 351 community-dwelling women free of major depression going through the MT, of whom 180 were assigned the intervention and 171 usual care. The primary outcome of interest was the incidence of clinically significant depressive symptoms over 52 weeks. Other study measures included the Hospital Anxiety and Depression Scale, quality of life (SF-12), the Menopause Rating Scale (MRS), diet, body mass index, alcohol use, smoking and physical activity. We considered that women with Patient Health Questionnaire (PHQ-9) scores between 5 and 14 (inclusive) had sub-threshold depressive symptoms.Results Nine women developed clinically significant symptoms of depression during the study-2 had been assigned HC (odds ratio, OR=0.26, 95%CI=0.05, 1.29; p=0.099). Intention-to-treat showed that, compared with usual care, the intervention led to a greater decline in depressive scores, most markedly for participants with sub-threshold depressive symptoms. Similar, but less pronounced, benefits were noticed for anxiety scores and the mental component summary of the SF-12. The intervention led to a decline in MRS scores by week 26 and subtle improvements in body mass, consumption of vegetables and smoking.Conclusions HC addressing relevant risk factors for depression during the MT improves mental health measures. Our findings indicate that women with sub-threshold depressive symptoms may benefit the most from such interventions, and suggest that HC could play a useful role in minimizing mental health disturbance for women going through the MT.
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- Authors
- Almeida, O. P., Marsh, K., Murray, K., Hickey, M., Sim, M., Ford, A., & Flicker, L.
- Affiliations
- The University of Western Australia (AU)
- Royal Women's Hospital (AU)
- Edith Cowan University (AU)
- Corresponding author
- Almeida, Osvaldo P.
- Venue
- Maturitas
- Publisher
- Elsevier BV
- Published
- 2016-10
- Volume
- 92
- Pages
- 41-48
- ISSN
- 0378-5122 (ISSN-L)
- OpenAlex
- W2494966211
- Cited by
- 21
- References
- 31
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 3 · 2023: 1 · 2022: 3 · 2021: 2 · 2020: 2 · 2019: 2 · 2018: 2 · 2017: 1 · 2016: 1
- FWCI
- 2.01
- Type
- journal article
- Language
- en
- Open access
- green
- ro.ecu.edu.au
- Locations
- Maturitas (publishedVersion)
- PubMed (publishedVersion)
- UWA Profiles and Research Repository (UWA) (submittedVersion)
- Australasian Journal of Paramedicine (submittedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Keywords
- perimenopause, depression, health coaching, telephone-delivered intervention, anxiety, quality of life, menopause, women's mental health, lifestyle risk factors
- MeSH terms
- Mentoring, Adult, Depression, Depressive Disorder, Major, Major Depressive Disorder, Female, Humans, Menopause, Middle Aged, Quality of Life, Severity of Illness Index, Treatment Outcome
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