Understanding Mohs Micrographic Surgery
Abstract
The incidence and diagnosis of cutaneous malignancies are steadily rising. In addition, with the aging population and increasing use of organ transplant and immunosuppressive medications, subsets of patients are now more susceptible to skin cancer. Mohs micrographic surgery (MMS) has become the standard of care for the treatment of high-risk nonmelanoma skin cancers and is increasingly used to treat melanoma. Mohs micrographic surgery has the highest cure rates, spares the maximal amount of normal tissue, and is cost-effective for the treatment of cutaneous malignancies. As in other medical fields, appropriate use criteria were developed for MMS and have become an evolving guideline for determining which patients and tumors are appropriate for referral to MMS. Patients with cutaneous malignancies often require multidisciplinary care. With the changing landscape of medicine and the rapidly increasing incidence of skin cancer, primary care providers and specialists who do not commonly manage cutaneous malignancies will need to have an understanding of MMS and its role in patient care. This review better familiarizes the medical community with the practice of MMS, its utilization and capabilities, differences from wide excision and vertical section pathology, and cost-effectiveness, and it guides practitioners in the process of appropriately evaluating and determining when patients with skin cancer might be appropriate candidates for MMS.
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Mohs micrographic surgery evaluates 100% of the surgical margins.
“MMS has the highest cure rates in the treatment of cutaneous carcinomas, as it evaluates 100% of the surgical margins, whereas the wide local excision technique assesses about 1% of the margins by”
From Auricular reconstruction after Mohs micrographic surgery: analysis of 101 cases (2021) · cites this paper as [6]
Wide local excision assesses about 1% of the surgical margins.
“MMS has the highest cure rates in the treatment of cutaneous carcinomas, as it evaluates 100% of the surgical margins, whereas the wide local excision technique assesses about 1% of the margins by”
From Auricular reconstruction after Mohs micrographic surgery: analysis of 101 cases (2021) · cites this paper as [6]
Mohs micrographic surgery has the highest cure rates in the treatment of cutaneous carcinomas.
“MMS has the highest cure rates in the treatment of cutaneous carcinomas, as it evaluates 100% of the surgical margins, whereas the wide local excision technique assesses about 1% of the margins by”
From Auricular reconstruction after Mohs micrographic surgery: analysis of 101 cases (2021) · cites this paper as [6]
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Auricular reconstruction after Mohs micrographic surgery: analysis of 101 cases
Bittner, G. C., Kubo, E. M., Fantini, B. D. C., & Cerci, F. B. (2021) · Anais Brasileiros de Dermatologia · doi:10.1016/j.abd.2020.12.008 · Cited by 14 · see citing works
“MMS has the highest cure rates in the treatment of cutaneous carcinomas, as it evaluates 100% of the surgical margins, whereas the wide local excision technique assesses about 1% of the margins by b̈read-loads̈ectioning.(5,6) Although MMS allows maximum preservation of healthy tissue, many auricular surgical wounds ar…”
Background
- Authors
- Tolkachjov, S. N., Brodland, D. G., Coldiron, B. M., Fazio, M. J., Hruza, G. J., Roenigk, R. K., Rogers, H. W., Zitelli, J. A., Winchester, D. S., & Harmon, C. B.
- Affiliations
- Dallas Surgical Group (US)
- University of Pittsburgh Medical Center (US)
- University of Cincinnati (US)
- Saint Louis University (US)
- Mayo Clinic (US)
- Advanced Dermatology (US)
- Corresponding author
- Tolkachjov, Stanislav N.
- Venue
- Mayo Clinic Proceedings
- Publisher
- Elsevier BV
- Published
- 2017-08
- Volume
- 92
- Issue
- 8
- Pages
- 1261-1271
- ISSN
- 0025-6196 (ISSN-L)
- OpenAlex
- W2739894312
- Cited by
- 91
- References
- 94
- Citations by year
- 2026: 8 · 2025: 10 · 2024: 8 · 2023: 9 · 2022: 15 · 2021: 14 · 2020: 18 · 2019: 4 · 2018: 4
- FWCI
- 0.94
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Mayo Clinic Proceedings (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Nonmelanoma Skin Cancer Studies
- Health Sciences › Medicine › Oncology › Cutaneous Melanoma Detection and Management
- Health Sciences › Medicine › Dermatology › Cancer and Skin Lesions
- Keywords
- Mohs micrographic surgery, skin cancer, non-melanoma skin cancer, melanoma, appropriate use criteria, wide local excision, cost-effectiveness, multidisciplinary care, immunocompromised patients, primary care providers
- MeSH terms
- Carcinoma, Squamous Cell, Cost-Benefit Analysis, Humans, Melanoma, Neoplasm Recurrence, Local, Skin Neoplasms, Mohs Surgery, Incidence
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