The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
Urgent Guidance for Navigating and Circumventing the QTc-Prolonging and Torsadogenic Potential of Possible Pharmacotherapies for Coronavirus Disease 19 (COVID-19)
Open accessAbstract
As the coronavirus disease 19 (COVID-19) global pandemic rages across the globe, the race to prevent and treat this deadly disease has led to the “off-label” repurposing of drugs such as hydroxychloroquine and lopinavir/ritonavir, which have the potential for unwanted QT-interval prolongation and a risk of drug-induced sudden cardiac death. With the possibility that a considerable proportion of the world’s population soon could receive COVID-19 pharmacotherapies with torsadogenic potential for therapy or postexposure prophylaxis, this document serves to help health care professionals mitigate the risk of drug-induced ventricular arrhythmias while minimizing risk of COVID-19 exposure to personnel and conserving the limited supply of personal protective equipment.
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1 retracted
Gautret, P., Lagier, J.-C., Parola, P., Hoang, V. T., Meddeb, L., Mailhe, M., Doudier, B., Courjon, J., Giordanengo, V., Vieira, V. E., et al. (2020) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2020.105949 · Cited by 5,288
RetractedClinical features of patients infected with 2019 novel coronavirus in Wuhan, China
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Wang, M., Cao, R., Zhang, L., Yang, X., Liu, J., Xu, M., Shi, Z., Hu, Z., Zhong, W., & Xiao, G. (2020) · Cell Research · doi:10.1038/s41422-020-0282-0 · Cited by 6,958
A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19
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Chloroquine is a potent inhibitor of SARS coronavirus infection and spread
Vincent, M. J., Bergeron, E., Benjannet, S., Erickson, B. R., Rollin, P. E., Ksiazek, T. G., Seidah, N. G., & Nichol, S. T. (2005) · Virology Journal · doi:10.1186/1743-422x-2-69 · Cited by 1,811
Effects of chloroquine on viral infections: an old drug against today's diseases
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Chloroquine and hydroxychloroquine as available weapons to fight COVID-19
Colson, P., Rolain, J.-M., Lagier, J.-C., Brouqui, P., & Raoult, D. (2020) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2020.105932 · Cited by 937 · cited 1×
“5, 6 In light of (1) the need for this practice to continue in the absence of viable, evidence-based therapies and (2) the proclivity of many promising COVID-19 pharmacotherapiesdspecifically antimalarial agents such as hydroxychloroquinedto prolong the QTc, thereby increasing the risk of drug-induced torsades de poin…”
International Recommendations for Electrocardiographic Interpretation in Athletes
Sharma, S., Drezner, J. A., Baggish, A., Papadakis, M., Wilson, M. G., Prutkin, J. M., La Gerche, A., Ackerman, M. J., Borjesson, M., Salerno, J. C., et al. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.01.015 · Cited by 598
Self-citationIn vitro susceptibility of 10 clinical isolates of SARS coronavirus to selected antiviral compounds
Chen, F., Chan, K. H., Jiang, Y., Kao, R. Y. T., Lu, H. T., Fan, K. W., Cheng, V. C. C., Tsui, W. H. W., Hung, I. F. N., & Lee, T. S. W. (2004) · Journal of Clinical Virology · doi:10.1016/j.jcv.2004.03.003 · Cited by 534
Cited by
Description and Proposed Management of the Acute COVID-19 Cardiovascular Syndrome
Hendren, N. S., Drazner, M. H., Bozkurt, B., & Cooper, L. T. (2020) · Circulation · doi:10.1161/circulationaha.120.047349 · Cited by 576
Wearable Sensing and Telehealth Technology with Potential Applications in the Coronavirus Pandemic
Ding, X., Clifton, D., Ji, N., Lovell, N. H., Bonato, P., Chen, W., Yu, X., Xue, Z., Xiang, T., Long, X., et al. (2021) · IEEE Reviews in Biomedical Engineering · doi:10.1109/rbme.2020.2992838 · Cited by 281
Cegolon, L., Javanbakht, M., & Mastrangelo, G. (2020) · International Journal of Hygiene and Environmental Health · doi:10.1016/j.ijheh.2020.113605 · Cited by 44
New FDA guidance on general clinical trial conduct in the era of COVID-19
Turner, J. R. (2020) · Therapeutic Innovation & Regulatory Science · doi:10.1007/s43441-020-00160-0 · Cited by 20
Metadata
- Authors
- Giudicessi, J. R., Noseworthy, P. A., Friedman, P. A., & Ackerman, M. J.
- Venue
- Mayo Clinic Proceedings
- Publisher
- Elsevier BV
- Published
- 2020-06
- Volume
- 95
- Issue
- 6
- Pages
- 1213-1221
- ISSN
- 0025-6196 (ISSN-L)
- OpenAlex
- W3015907249
- Cited by
- 394
- References
- 26
- FWCI
- 52.51
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Urgent Guidance for Navigating and Circumventing the QTc-Prolonging and Torsadogenic Potential of Possible Pharmacotherapies for Coronavirus Disease 19 (COVID-19). https://app.cochat.ai/papers/10.1016/j.mayocp.2020.03.024
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- Giudicessi, J. R., Noseworthy, P. A., Friedman, P. A., & Ackerman, M. J. (2020). Urgent Guidance for Navigating and Circumventing the QTc-Prolonging and Torsadogenic Potential of Possible Pharmacotherapies for Coronavirus Disease 19 (COVID-19). Mayo Clinic Proceedings. https://doi.org/10.1016/j.mayocp.2020.03.024
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
