Disturbed expression of phase I and phase II estrogen-metabolizing enzymes in endometrial cancer: lower levels of CYP1B1 and increased expression of S-COMT

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Vandesompele, J., De Preter, K., Pattyn, F., Poppe, B., Van Roy, N., De Paepe, A., & Speleman, F. (2002) · Genome Biology · doi:10.1186/gb-2002-3-7-research0034 · Cited by 20,038 · see citing works

Global Cancer Statistics, 2002

Parkin, D. M., Bray, F., Ferlay, J., & Pisani, P. (2005) · CA A Cancer Journal for Clinicians · doi:10.3322/canjclin.55.2.74 · Cited by 18,573 · see citing works

The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments

Bustin, S. A., Benes, V., Garson, J. A., Hellemans, J., Huggett, J., Kubista, M., Mueller, R., Nolan, T., Pfaffl, M. W., Shipley, G. L., et al. (2009) · Clinical Chemistry · doi:10.1373/clinchem.2008.112797 · Cited by 16,303 · see citing works

Global cancer statistics

Parkin, D. M., Pisani, P., & Ferlay, J. (1999) · CA A Cancer Journal for Clinicians · doi:10.3322/canjclin.49.1.33 · Cited by 3,398 · see citing works

Estrogen Carcinogenesis in Breast Cancer

Yager, J. D., & Davidson, N. E. (2006) · New England Journal of Medicine · doi:10.1056/nejmra050776 · Cited by 1,863 · see citing works

Kinetics of Human Soluble and Membrane-Bound Catechol O-Methyltransferase: A Revised Mechanism and Description of the Thermolabile Variant of the Enzyme

Lotta, T. I., Vidgren, J., Tilgmann, C., Ulmanen, I., Melén, K., Julkunen, I., & Taskinen, J. (1995) · Biochemistry · doi:10.1021/bi00013a008 · Cited by 1,167 · see citing works

Catechol-O-methyltransferase (COMT): biochemistry, molecular biology, pharmacology, and clinical efficacy of the new selective COMT inhibitors

Männistö, P. T., & Kaakkola, S. (1999) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01423-6 · Cited by 1,068 · see citing works

Functional role of estrogen metabolism in target cells: review and perspectives

Zhu, B. T. (1998) · Carcinogenesis · doi:10.1093/carcin/19.1.1 · Cited by 964 · see citing works

Hormonal carcinogenesis

Henderson, B. E., & Feigelson, H. S. (2000) · Carcinogenesis · doi:10.1093/carcin/21.3.427 · Cited by 821 · see citing works

Molecular and Pathologic Aspects of Endometrial Carcinogenesis

Hecht, J. L., & Mutter, G. L. (2006) · Journal of Clinical Oncology · doi:10.1200/jco.2006.06.7173 · Cited by 536 · see citing works

Is Estradiol a Genotoxic Mutagenic Carcinogen?1

Liehr, J. G. (2000) · Endocrine Reviews · doi:10.1210/edrv.21.1.0386 · Cited by 486 · see citing works

Characterization of the Oxidative Metabolites of 17β-Estradiol and Estrone Formed by 15 Selectively Expressed Human Cytochrome P450 Isoforms

Lee, A. J., Cai, M. X., Thomas, P. E., Conney, A. H., & Zhu, B. T. (2003) · Endocrinology · doi:10.1210/en.2003-0192 · Cited by 457 · see citing works

Catechol estrogen quinones as initiators of breast and other human cancers: Implications for biomarkers of susceptibility and cancer prevention

Cavalieri, E. L., Chakravarti, D., Guttenplan, J. B., Hart, E., Ingle, J. N., Jankowiak, R., Muti, P. C., Rogan, E. G., Russo, J., Santen, R. J., et al. (2006) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2006.03.001 · Cited by 408 · see citing works

Chapter 3: Endogenous Estrogens as Carcinogens Through Metabolic Activation

Yager, J. D. (2000) · JNCI Monographs · doi:10.1093/oxfordjournals.jncimonographs.a024245 · Cited by 399 · see citing works

Genomic organization of the human catechol <i>O</i>‐methyltransferase gene and its expression from two distinct promoters

TENHUNEN, J., SALMINEN, M., LUNDSTRÖM, K., KIVILUOTO, T., SAVOLAINEN, R., & ULMANEN, I. (1994) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1994.tb19083.x · Cited by 331 · see citing works

Chapter 6: Estrogen Metabolism by Conjugation

Raftogianis, R. B., Creveling, C. R., Weinshilboum, R. M., & Weisz, J. (2000) · JNCI Monographs · doi:10.1093/oxfordjournals.jncimonographs.a024234 · Cited by 297 · see citing works

Quantitative Structure-Activity Relationship of Various Endogenous Estrogen Metabolites for Human Estrogen Receptor α and β Subtypes: Insights into the Structural Determinants Favoring a Differential Subtype Binding

Zhu, B. T., Han, G.-Z., Shim, J.-Y., Wen, Y., & Jiang, X.-R. (2006) · Endocrinology · doi:10.1210/en.2006-0113 · Cited by 271 · see citing works

Potential Mechanisms of Estrogen Quinone Carcinogenesis

Bolton, J. L., & Thatcher, G. R. J. (2007) · Chemical Research in Toxicology · doi:10.1021/tx700191p · Cited by 241 · see citing works

Is Estradiol a Genotoxic Mutagenic Carcinogen?

Liehr, J. G. (2000) · Endocrine Reviews · doi:10.1210/er.21.1.40 · Cited by 235 · see citing works

Genetic polymorphism and function of glutathione S-transferases in tumor drug resistance

Lo, H., & Ali‐Osman, F. (2007) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2007.06.009 · Cited by 217 · see citing works

Specificity and regioselectivity of the conjugation of estradiol, estrone, and their catecholestrogen and methoxyestrogen metabolites by human uridine diphospho-glucuronosyltransferases expressed in endometrium

Lépine, J., Bernard, O., Plante, M., Têtu, B., Pelletier, G., Labrie, F., Bélanger, A., & Guillemette, C. (2004) · The Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/jc.2004-0331 · Cited by 205 · see citing works

Recent insight on the control of enzymes involved in estrogen formation and transformation in human breast cancer

Pasqualini, J. R., & Chetrite, G. S. (2005) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2005.02.007 · Cited by 194 · see citing works

An immunohistochemical study of pi class glutathione S-transferase expression in normal human tissue.

Terrier, P., Townsend, A. J., Coindre, J., et al. (1990) · PubMed · Cited by 163 · see citing works

Estrogen metabolism and action in endometriosis

Rižner, T. L. (2009) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2009.03.022 · Cited by 153 · see citing works

Molecular Carcinogenesis of Endometrial Cancer

Liu, F.-S. (2007) · Taiwanese Journal of Obstetrics and Gynecology · doi:10.1016/s1028-4559(08)60102-3 · Cited by 141 · see citing works

Molecular Profiling of Endometrial Malignancies

Samarnthai, N., Hall, K. L., & Yeh, I. (2010) · Obstetrics and Gynecology International · doi:10.1155/2010/162363 · Cited by 134 · see citing works

Metabolic inactivation of estrogens in breast tissue by UDP-glucuronosyltransferase enzymes: an overview

Guillemette, C., Bélanger, A., & Lépine, J. (2004) · Breast Cancer Research · doi:10.1186/bcr936 · Cited by 123 · see citing works

Catecholestrogen Sulfation: Possible Role in Carcinogenesis

Adjei, A. A., & Weinshilboum, R. M. (2002) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2002.6658 · Cited by 105 · see citing works

Inhibition of Catechol O-Methyltransferase-catalyzed O-Methylation of 2- and 4-Hydroxyestradiol by Quercetin

Zhu, B. T., & Liehr, J. G. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.3.1357 · Cited by 105 · see citing works

Catechol Quinones of Estrogens in the Initiation of Breast, Prostate, and Other Human Cancers

Cavalieri, E. L., & Rogan, E. G. (2006) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1386.042 · Cited by 102 · see citing works

Human estrogen sulfotransferase (SULT1E1) pharmacogenomics: gene resequencing and functional genomics

Adjei, A. A., Thomae, B. A., Prondzinski, J. L., Eckloff, B. W., Wieben, E. D., & Weinshilboum, R. M. (2003) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0705369 · Cited by 98 · see citing works

Glucuronidation of Catechol Estrogens by Expressed Human UDP-Glucuronosyltransferases (UGTs) 1A1, 1A3, and 2B7,

Cheng, Z. (1998) · Toxicological Sciences · doi:10.1006/toxs.1998.2494 · Cited by 97 · see citing works

Biochemical and Molecular Modeling Studies of the O -Methylation of Various Endogenous and Exogenous Catechol Substrates Catalyzed by Recombinant Human Soluble and Membrane-Bound Catechol- O -Methyltransferases

Bai, H., Shim, J., Yu, J., & Zhu, B. T. (2007) · Chemical Research in Toxicology · doi:10.1021/tx700174w · Cited by 90 · see citing works

CYP1A1, SULT1A1, and SULT1E1 polymorphisms are risk factors for endometrial cancer susceptibility

Hirata, H., Hinoda, Y., Okayama, N., Suehiro, Y., Kawamoto, K., Kikuno, N., Rabban, J. T., Chen, L. M., & Dahiya, R. (2008) · Cancer · doi:10.1002/cncr.23392 · Cited by 87 · see citing works

Molecular Analysis of Endometrial Tumorigenesis: Importance of Complex Hyperplasia Regardless of Atypia

Nieminen, T. T., Gylling, A., Abdel‐Rahman, W. M., et al. (2009) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-09-0506 · Cited by 83 · see citing works

NADPH-dependent metabolism of 17β-estradiol and estrone to polar and nonpolar metabolites by human tissues and cytochrome P450 isoforms

Zhu, B. T., & Lee, A. J. (2005) · Steroids · doi:10.1016/j.steroids.2005.01.002 · Cited by 80 · see citing works

Genotoxicity of hormonal steroids

Joosten, H. F. P., van Acker, F. A. A., van den Dobbelsteen, D. J., et al. (2004) · Toxicology Letters · doi:10.1016/j.toxlet.2004.01.018 · Cited by 75 · see citing works

Circulating Estrogens in Endometrial Cancer Cases and Their Relationship with Tissular Expression of Key Estrogen Biosynthesis and Metabolic Pathways

Lépine, J., Audet‐Walsh, É., Grégoire, J., Têtu, B., Plante, M., Ménard, V., Ayotte, P., Brisson, J., Caron, P., Villeneuve, L., et al. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-2648 · Cited by 75 · see citing works

Tumor estrogen content and clinico-morphological and endocrine features of endometrial cancer

Berstein, L. M., Tchernobrovkina, A. E., Gamajunova, V. B., Ковалевский, А. Ю., Vasilyev, D. A., Чепик, О. Ф., Turkevich, E. A., Tsyrlina, E. V., Maximov, S., Андреевич, А. Л., et al. (2003) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-003-0427-9 · Cited by 73 · see citing works

Multiple promoters of catechol-O-methyltransferase gene are selectively inactivated by CpG hypermethylation in endometrial cancer.

Sasaki, M., Kaneuchi, M., Sakuragi, N., & Dahiya, R. (2003) · PubMed · Cited by 64 · see citing works

Functional Significance of CytochromeP450 1B1 in Endometrial Carcinogenesis

Saini, S., Hirata, H., Majid, S., et al. (2009) · Cancer Research · doi:10.1158/0008-5472.can-09-1691 · Cited by 60 · see citing works

Catecholestrogens induce oxidative stress and malignant transformation in human endometrial glandular cells: Protective effect of catechol‐O‐methyltransferase

Salama, S. A., Kamel, M., Awad, M. M., et al. (2008) · International Journal of Cancer · doi:10.1002/ijc.23653 · Cited by 54 · see citing works

Promoter Methylation and Differential Expression of π-Class Glutathione S-Transferase in Endometrial Carcinoma

Chan, Q. K. Y., Khoo, U., Chan, K. Y. K., Ngan, H., Li, S., Chiu, P. M., Man, L.-S., Ip, P. P. C., Xue, W., & Cheung, A. (2005) · Journal of Molecular Diagnostics · doi:10.1016/s1525-1578(10)60003-7 · Cited by 53 · see citing works

Hormone Replacement Therapy and Cancers: The Biological Roles of Estrogen and Progestin in Tumorigenesis are Different between the Endometrium and Breast

Ito, K. (2007) · The Tohoku Journal of Experimental Medicine · doi:10.1620/tjem.212.1 · Cited by 45 · see citing works

Elevated Estrogen 16 -Hydroxylase Activity: Is This a Genotoxic or Nongenotoxic Biomarker in Human Breast Cancer Risk?

Nebert, D. W. (1993) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/85.23.1888 · Cited by 42 · see citing works

CYP1B1 gene in endometrial cancer

Sasaki, M., Kaneuchi, M., Fujimoto, S., Tanaka, Y., & Dahiya, R. (2003) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(03)00079-0 · Cited by 40 · see citing works

Formation of catechol estrogen glutathione conjugates and gamma- glutamyl transpeptidase-dependent nephrotoxicity of 17beta-estradiol in the golden Syrian hamster

Butterworth, M. (1997) · Carcinogenesis · doi:10.1093/carcin/18.3.561 · Cited by 39 · see citing works

078 Multiple Promoters of Catechol-O-Methyltransferase Gene Are Selectively Inactivated By CPG Hypermethylation in Endometrial Cancer

Sasaki, M., Karube, A., Karube, Y., Sakuragi, N., Fujimoto, S., & Dahiya, R. (2004) · International Journal of Gynecological Cancer · doi:10.1136/ijgc-00009577-200409001-00078 · Cited by 39 · see citing works

Purification and Kinetic Mechanism of Human Brain Soluble Catechol‐O‐Methyltransferase

Jeffery, D., & Roth, J. A. (1985) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1985.tb12898.x · Cited by 30 · see citing works

Estrogen Exposure, Metabolism, and Enzyme Variants in a Model for Breast Cancer Risk Prediction

Parl, F. F., Egan, K. M., Li, C., et al. (2009) · Cancer Informatics · doi:10.4137/cin.s2262 · Cited by 29 · see citing works

Glucuronidation of Catechol Estrogens by Expressed Human UDP-Glucuronosyltransferases (UGTs) 1A1, 1A3, and 2B7

Cheng, Z., Rios, G. R., King, C. D., et al. (1998) · Toxicological Sciences · doi:10.1093/toxsci/45.1.52 · Cited by 28 · see citing works

Induction of NAD(P)H quinone oxidoreductase and glutathione S-transferase activities in livers of female August-Copenhagen Irish rats treated chronically with estradiol: comparison with the Sprague–Dawley rat

Sánchez, R. I., Mesía-Vela, S., & Kauffman, F. C. (2003) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2003.08.007 · Cited by 21 · see citing works

Quantifiable mRNA transcripts for tamoxifen-metabolising enzymes in human endometrium

Singh, M. N., Stringfellow, H. F., Walsh, M. J., Ashton, K. M., Paraskevaidis, E. A., Abdo, K. R., Martin‐Hirsch, P. L., Phillips, D. H., & Martin, F. L. (2008) · Toxicology · doi:10.1016/j.tox.2008.04.009 · Cited by 19 · see citing works

Separation methods for catechol O-methyltransferase activity assay: physiological and pathophysiological relevance

Pihlavisto, P., & Reenilä, I. (2002) · Journal of Chromatography B · doi:10.1016/s1570-0232(02)00429-4 · Cited by 18 · see citing works

Biochemical and computational insights into the anti-aromatase activity of natural catechol estrogens

Neves, M. A. C., Dinis, T. C. P., Colombo, G., et al. (2008) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2007.10.011 · Cited by 9 · see citing works

[Co-occurrence of hyperplasia, endometrial carcinoma and uterine myoma: role of sex hormones, their receptors and enzymes of estrogen metabolism].

Nv, B., Коломиец, Л. А., & Кондакова, И. В. (2005) · PubMed · Cited by 1 · see citing works

Human steroid biosynthesis, metabolism and excretion are differentially reflected by serum and urine steroid metabolomes: a comprehensive review

Schiffer, L., Barnard, L., Baranowski, E. S., Gilligan, L. C., Taylor, A. E., Arlt, W., Shackleton, C. H. L., & Storbeck, K.-H. (2019) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2019.105439 · Cited by 450 · see citing works

Fisetin disposition and metabolism in mice: Identification of geraldol as an active metabolite

Touil, Y. S., Auzeil, N., Boulinguez, F., Saighi, H., Regazzetti, A., Scherman, D., & Chabot, G. G. (2011) · Biochemical Pharmacology · doi:10.1016/j.bcp.2011.07.097 · Cited by 111 · see citing works

The important roles of steroid sulfatase and sulfotransferases in gynecological diseases

Rižner, T. L. (2016) · Frontiers in Pharmacology · doi:10.3389/fphar.2016.00030 · Cited by 98 · see citing works

The Significance of the Sulfatase Pathway for Local Estrogen Formation in Endometrial Cancer

Sinreih, M., Knific, T., Anko, M., Hevir, N., Vouk, K., Jerin, A., Frković Grazio, S., & Rižner, T. L. (2017) · Frontiers in Pharmacology · doi:10.3389/fphar.2017.00368 · Cited by 33 · see citing works

Characterization of the Dose–Response of CYP1B1, CYP1A1, and CYP1A2 in the Liver of Female Sprague–Dawley Rats Following Chronic Exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin

Walker, N. J., Portier, C. J., Lax, S., Crofts, F., Li, Y., Lucier, G. W., & Sutter, T. R. (1999) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1998.8595 · Cited by 90 · see citing works

Piperonyl butoxide and acenaphthylene induce cytochrome P450 1A2 and 1B1 mRNA in aromatic hydrocarbon-responsive receptor knock-out mouse liver.

Ryu, D.-Y., Levi, P. E., Fernández‐Salguero, P. M., et al. (1996) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)09289-2 · Cited by 91 · see citing works

Differential expression of CYP1A1 and CYP1A2 genes in H4IIE rat hepatoma cells exposed to TCDD and PAHs

Kaišarević, S., Dakić, V., Hrubik, J., Glišić, B., Varel, U. L., Pogrmic‐Majkic, K., Fa, S., Teodorović, I., Brack, W., & Kovačević, R. M. (2014) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2014.11.031 · Cited by 17 · see citing works

Inhibition of procarcinogen‐bioactivating human CYP1A1, CYP1A2 and CYP1B1 enzymes by melatonin

Chang, T. K. H., Chen, J., Yang, G., & Yeung, E. Y. H. (2009) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2009.00724.x · Cited by 50 · see citing works

Real-Time Polymerase Chain Reaction Analysis of CYP1B1 Gene Expression in Human Liver

Chang, T. K. H. (2003) · Toxicological Sciences · doi:10.1093/toxsci/71.1.11 · Cited by 78 · see citing works