The DOI matches its Crossref record; 149 of the 149 references it cites were found in a registry or an index.
The estrogenic endocrine disrupting chemical bisphenol A (BPA) and obesity
Open accessAbstract
There is increasing experimental and epidemiological evidence that fetal programming of genetic systems is a contributing factor in the recent increase in adult obesity and other components of metabolic syndrome. In particular, there is evidence that epigenetic changes associated with the use of manmade chemicals may interact with other factors that influence fetal and postnatal growth in contributing to the current obesity epidemic. The focus of this review is on the developmental effects of estrogenic endocrine disrupting chemicals (EDCs), and more specifically on effects of exposure to the estrogenic EDC bisphenol A (BPA), on adipocytes and their function, and the ultimate impact on adult obesity; BPA exposure also results in impaired reproductive capacity. We discuss the interaction of EDCs with other factors that impact growth during fetal and neonatal life, such as placental blood flow and nutrient transport to fetuses, and how these influence fetal growth and abnormalities in homeostatic control systems required to maintain normal body weight throughout life.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
1 retracted
The Prostaglandin Transporter Regulates Adipogenesis and Aromatase Transcription
Subbaramaiah, K., Hudis, C. A., & Dannenberg, A. J. (2011) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-10-0367 · Cited by 16
RetractedPrevalence of Overweight and Obesity in the United States, 1999-2004
Ogden, C. L., Carroll, M. D., Curtin, L. R., McDowell, M. A., Tabak, C. J., & Flegal, K. M. (2006) · JAMA · doi:10.1001/jama.295.13.1549 · Cited by 8,720
Endocrine-Disrupting Chemicals: An Endocrine Society Scientific Statement
Diamanti-Kandarakis, E., Bourguignon, J.-P., Giudice, L. C., Hauser, R., Prins, G. S., Soto, A. M., Zoeller, R. T., & Gore, A. C. (2009) · Endocrine Reviews · doi:10.1210/er.2009-0002 · Cited by 4,585
Prevalence of Overweight and Obesity in the United States
Crespo, C. J., & Ellen, S. (2003) · Obesity: Etiology Assessment Treatment and Prevention · doi:10.5040/9781718206601.ch-001 · Cited by 4,379
Developmental effects of endocrine-disrupting chemicals in wildlife and humans.
Colborn, T., vom Saal, F. S., & Soto, A. M. (1993) · Environmental Health Perspectives · doi:10.1289/ehp.93101378 · Cited by 3,445
Self-citationHuman exposure to bisphenol A (BPA)
Vandenberg, L. N., Hauser, R., Marcus, M., Olea, N., & Welshons, W. V. (2007) · Reproductive Toxicology · doi:10.1016/j.reprotox.2007.07.010 · Cited by 2,885
Adipocyte differentiation from the inside out
Rosen, E. D., & MacDougald, O. A. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2066 · Cited by 2,607
Understanding Adipocyte Differentiation
GREGOIRE, F. M., SMAS, C. M., & SUL, H. S. (1998) · Physiological Reviews · doi:10.1152/physrev.1998.78.3.783 · Cited by 2,376
The Developmental Origins of Adult Disease
Barker, D. J. P. (2004) · Journal of the American College of Nutrition · doi:10.1080/07315724.2004.10719428 · Cited by 1,854
Lang, I. A. (2008) · JAMA · doi:10.1001/jama.300.11.1303 · Cited by 1,458
Cited by
EDC-2: the endocrine society's second scientific statement on endocrine-disrupting chemicals
Gore, A. C., Chappell, V. A., Fenton, S. E., Flaws, J. A., Nadal, A., Prins, G. S., Toppari, J., & Zoeller, R. T. (2015) · Endocrine Reviews · doi:10.1210/er.2015-1010 · Cited by 2,407
Early Developmental Conditioning of Later Health and Disease: Physiology or Pathophysiology?
Hanson, M. A., & Gluckman, P. D. (2014) · Physiological Reviews · doi:10.1152/physrev.00029.2013 · Cited by 1,188
A Review of Human Exposure to Microplastics and Insights Into Microplastics as Obesogens
Kannan, K., & Vimalkumar, K. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.724989 · Cited by 607
Microplastics: an emerging threat to food security and human health
De-la-Torre, G. E. (2020) · Journal of Food Science and Technology · doi:10.1007/s13197-019-04138-1 · Cited by 492
Chen, Q., Yin, D., Jia, Y., Schiwy, S., Legradi, J., Yang, S., & Hollert, H. (2017) · Science of The Total Environment · doi:10.1016/j.scitotenv.2017.07.144 · Cited by 474
Metadata
- Authors
- vom Saal, F. S., Nagel, S. C., Coe, B. L., Angle, B. M., & Taylor, J. A.
- Venue
- Molecular and Cellular Endocrinology
- Publisher
- Elsevier BV
- Published
- 2012-05
- Volume
- 354
- Issue
- 1-2
- Pages
- 74-84
- ISSN
- 0303-7207 (ISSN-L)
- OpenAlex
- W2171338004
- Cited by
- 450
- References
- 149
- FWCI
- 24.22
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: The estrogenic endocrine disrupting chemical bisphenol A (BPA) and obesity. https://app.cochat.ai/papers/10.1016/j.mce.2012.01.001
- The paper
- vom Saal, F. S., Nagel, S. C., Coe, B. L., Angle, B. M., & Taylor, J. A. (2012). The estrogenic endocrine disrupting chemical bisphenol A (BPA) and obesity. Molecular and Cellular Endocrinology. https://doi.org/10.1016/j.mce.2012.01.001
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.