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Cited by 450

The DOI matches its Crossref record; 149 of the 149 references it cites were found in a registry or an index.

The estrogenic endocrine disrupting chemical bisphenol A (BPA) and obesity

Open access
vom Saal, Frederick S., Nagel, Susan C., Coe, Benjamin L., Angle, Brittany M., Taylor, Julia A.·2012·Molecular and Cellular Endocrinology

Abstract

There is increasing experimental and epidemiological evidence that fetal programming of genetic systems is a contributing factor in the recent increase in adult obesity and other components of metabolic syndrome. In particular, there is evidence that epigenetic changes associated with the use of manmade chemicals may interact with other factors that influence fetal and postnatal growth in contributing to the current obesity epidemic. The focus of this review is on the developmental effects of estrogenic endocrine disrupting chemicals (EDCs), and more specifically on effects of exposure to the estrogenic EDC bisphenol A (BPA), on adipocytes and their function, and the ultimate impact on adult obesity; BPA exposure also results in impaired reproductive capacity. We discuss the interaction of EDCs with other factors that impact growth during fetal and neonatal life, such as placental blood flow and nutrient transport to fetuses, and how these influence fetal growth and abnormalities in homeostatic control systems required to maintain normal body weight throughout life.

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Crossref · 10.1016/j.mce.2012.01.001

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Metadata

Authors
vom Saal, F. S., Nagel, S. C., Coe, B. L., Angle, B. M., & Taylor, J. A.
Venue
Molecular and Cellular Endocrinology
Publisher
Elsevier BV
Published
2012-05
Volume
354
Issue
1-2
Pages
74-84
ISSN
0303-7207 (ISSN-L)
OpenAlex
W2171338004
Cited by
450
References
149
FWCI
24.22
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: The estrogenic endocrine disrupting chemical bisphenol A (BPA) and obesity. https://app.cochat.ai/papers/10.1016/j.mce.2012.01.001
The paper
vom Saal, F. S., Nagel, S. C., Coe, B. L., Angle, B. M., & Taylor, J. A. (2012). The estrogenic endocrine disrupting chemical bisphenol A (BPA) and obesity. Molecular and Cellular Endocrinology. https://doi.org/10.1016/j.mce.2012.01.001

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.