Student or educator? Sign up with your school email and get 6 months of Pro free.
Cited by 192

The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.

Anemia of Inflammation

Fraenkel, Paula G.·2017·Medical Clinics of North America

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/j.mcna.2016.09.005

Cites

25 of 25 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 25 references

Research works printed but not linked: 43

  1. Guralnik, 2004, Prevalence of anemia in persons 65 years and older in the United States: evidence for a high rate of unexplained anemia, Blood, 104, 2263, 10.1182/blood-2004-05-1812 · DOI · Paper page
  2. van Iperen, 2000, Response of erythropoiesis and iron metabolism to recombinant human erythropoietin in intensive care unit patients, Crit Care Med, 28, 2773, 10.1097/00003246-200008000-00015 · DOI
  3. Corwin, 2004, The CRIT study: anemia and blood transfusion in the critically ill–current clinical practice in the United States, Crit Care Med, 32, 39, 10.1097/01.CCM.0000104112.34142.79 · DOI · Paper page
  4. Joosten, 2014, Iron deficiency anemia and anemia of chronic disease in geriatric hospitalized patients: how frequent are comorbidities as an additional explanation for the anemia?, Geriatr Gerontol Int, 15, 931, 10.1111/ggi.12371 · DOI
  5. Coimbra, 2013, The role of adipocytes in the modulation of iron metabolism in obesity, Obes Rev, 14, 771, 10.1111/obr.12057 · DOI
  6. Thomas, 2013, Guideline for the laboratory diagnosis of functional iron deficiency, Br J Haematol, 161, 639, 10.1111/bjh.12311 · DOI · Paper page
  7. Anty, 2008, Bariatric surgery can correct iron depletion in morbidly obese women: a link with chronic inflammation, Obes Surg, 18, 709, 10.1007/s11695-007-9276-y · DOI
  8. Maccio, 2015, The role of inflammation, iron, and nutritional status in cancer-related anemia: results of a large, prospective, observational study, Haematologica, 100, 124, 10.3324/haematol.2014.112813 · DOI
  9. Ganz, 2016, Iron balance and the role of hepcidin in chronic kidney disease, Semin Nephrol, 36, 87, 10.1016/j.semnephrol.2016.02.001 · DOI
  10. Fraenkel, 2005, Ferroportin1 is required for normal iron cycling in zebrafish, J Clin Invest, 115, 1532, 10.1172/JCI23780 · DOI
  11. Bolondi, 2010, Altered hepatic BMP signaling pathway in human HFE hemochromatosis, Blood Cells Mol Dis, 45, 308, 10.1016/j.bcmd.2010.08.010 · DOI
  12. Ganz, 2012, Iron metabolism: interactions with normal and disordered erythropoiesis, Cold Spring Harb Perspect Med, 2, a011668, 10.1101/cshperspect.a011668 · DOI
  13. Arndt, 2010, Iron-induced expression of bone morphogenic protein 6 in intestinal cells is the main regulator of hepatic hepcidin expression in vivo, Gastroenterology, 138, 372, 10.1053/j.gastro.2009.09.048 · DOI
  14. Gibert, 2011, BMP signaling modulates hepcidin expression in zebrafish embryos independent of hemojuvelin, PLoS One, 6, e14553, 10.1371/journal.pone.0014553 · DOI
  15. Niederkofler, 2005, Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload, J Clin Invest, 115, 2180, 10.1172/JCI25683 · DOI · Paper page
  16. Zhang, 2007, Evidence that inhibition of hemojuvelin shedding in response to iron is mediated through neogenin, J Biol Chem, 282, 12547, 10.1074/jbc.M608788200 · DOI
  17. Finberg, 2008, Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA), Nat Genet, 40, 569, 10.1038/ng.130 · DOI · Paper page
  18. Melis, 2008, A mutation in the TMPRSS6 gene, encoding a transmembrane serine protease that suppresses hepcidin production, in familial iron deficiency anemia refractory to oral iron, Haematologica, 93, 1473, 10.3324/haematol.13342 · DOI
  19. Lee, 2005, Regulation of hepcidin transcription by interleukin-1 and interleukin-6, Proc Natl Acad Sci U S A, 102, 1906, 10.1073/pnas.0409808102 · DOI · Paper page
  20. Weizer-Stern, 2007, Hepcidin, a key regulator of iron metabolism, is transcriptionally activated by p53, Br J Haematol, 138, 253, 10.1111/j.1365-2141.2007.06638.x · DOI
  21. Kemna, 2005, Time-course analysis of hepcidin, serum iron, and plasma cytokine levels in humans injected with LPS, Blood, 106, 1864, 10.1182/blood-2005-03-1159 · DOI · Paper page
  22. Ganz, 2012, Hepcidin and iron homeostasis, Biochim Biophys Acta, 1823, 1434, 10.1016/j.bbamcr.2012.01.014 · DOI · Paper page
  23. Oliveira, 2009, ER stress-inducible factor CHOP affects the expression of hepcidin by modulating C/EBPalpha activity, PLoS One, 4, e6618, 10.1371/journal.pone.0006618 · DOI
  24. Millonig, 2012, Sustained submicromolar H2O2 levels induce hepcidin via signal transducer and activator of transcription 3 (STAT3), J Biol Chem, 287, 37472, 10.1074/jbc.M112.358911 · DOI
  25. Constante, 2006, Distinct requirements for HFE in basal and induced hepcidin levels in iron overload and inflammation, Am J Physiol Gastrointest Liver Physiol, 291, G229, 10.1152/ajpgi.00092.2006 · DOI
  26. Valdes-Ferrer, 2015, HMGB1 mediates anemia of inflammation in murine sepsis survivors, Mol Med, 21, 951, 10.2119/molmed.2015.00243 · DOI
  27. Yang, 2015, MD-2 is required for disulfide HMGB1-dependent TLR4 signaling, J Exp Med, 212, 5, 10.1084/jem.20141318 · DOI · Paper page
  28. Tracey, 1988, Cachectin/tumor necrosis factor induces cachexia, anemia, and inflammation, J Exp Med, 167, 1211, 10.1084/jem.167.3.1211 · DOI · Paper page
  29. Flo, 2004, Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron, Nature, 432, 917, 10.1038/nature03104 · DOI · Paper page
  30. Kanwar, 2015, Multifunctional iron bound lactoferrin and nanomedicinal approaches to enhance its bioactive functions, Molecules, 20, 9703, 10.3390/molecules20069703 · DOI
  31. Chung, 2007, Leptin increases the expression of the iron regulatory hormone hepcidin in HuH7 human hepatoma cells, J Nutr, 137, 2366
  32. Catalan, 2015, Peripheral mononuclear blood cells contribute to the obesity-associated inflammatory state independently of glycemic status: involvement of the novel proinflammatory adipokines chemerin, chitinase-3-like protein 1, lipocalin-2 and osteopontin, Genes Nutr, 10, 460, 10.1007/s12263-015-0460-8 · DOI
  33. Dinkla, 2016, Inflammation-associated changes in lipid composition and the organization of the erythrocyte membrane, BBA Clin, 5, 186, 10.1016/j.bbacli.2016.03.007 · DOI
  34. Georgatzakou, 2016, Red blood cell abnormalities and the pathogenesis of anemia in end stage renal disease, Proteomics Clin Appl, 10, 778, 10.1002/prca.201500127 · DOI
  35. Nemeth, 2014, Anemia of inflammation, Hematol Oncol Clin North Am, 28, 671, 10.1016/j.hoc.2014.04.005 · DOI · Paper page
  36. Blay, 1993, Role of interleukin-6 in paraneoplastic thrombocytosis, Blood, 82, 2261, 10.1182/blood.V82.7.2261.2261 · DOI
  37. Rossi, 2015, Interleukin-6 as a therapeutic target, Clin Cancer Res, 21, 1248, 10.1158/1078-0432.CCR-14-2291 · DOI · Paper page
  38. van Rhee, 2014, Siltuximab for multicentric Castleman's disease: a randomised, double-blind, placebo-controlled trial, Lancet Oncol, 15, 966, 10.1016/S1470-2045(14)70319-5 · DOI · Paper page
  39. Garcia-Manero, 2014, A phase 2, randomized, double-blind, multicenter study comparing siltuximab plus best supportive care (BSC) with placebo plus BSC in anemic patients with International Prognostic Scoring System low- or intermediate-1-risk myelodysplastic syndrome, Am J Hematol, 89, E156, 10.1002/ajh.23780 · DOI
  40. Cooke, 2013, A fully human anti-hepcidin antibody modulates iron metabolism in both mice and nonhuman primates, Blood, 122, 3054, 10.1182/blood-2013-06-505792 · DOI · Paper page
  41. Gaun, 2014, A chemical screen identifies small molecules that regulate hepcidin expression, Blood Cells Mol Dis, 53, 231, 10.1016/j.bcmd.2014.06.002 · DOI · Paper page
  42. Alkhateeb, 2015, The small molecule ferristatin II induces hepatic hepcidin expression in vivo and in vitro, Am J Physiol Gastrointest Liver Physiol, 308, G1019, 10.1152/ajpgi.00324.2014 · DOI
  43. Richardson, 2013, Isocitrate ameliorates anemia by suppressing the erythroid iron restriction response, J Clin Invest, 123, 3614, 10.1172/JCI68487 · DOI · Paper page

Cited by

See all 192

Metadata

Authors
Fraenkel, P. G.
Venue
Medical Clinics of North America
Publisher
Elsevier BV
Published
2017-03
Volume
101
Issue
2
Pages
285-296
ISSN
0025-7125
Cited by
192
References
25
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Anemia of Inflammation. https://app.cochat.ai/papers/10.1016/j.mcna.2016.09.005
The paper
Fraenkel, P. G. (2017). Anemia of Inflammation. Medical Clinics of North America. https://doi.org/10.1016/j.mcna.2016.09.005

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.