The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Predicting the angiotensin converting enzyme 2 (ACE2) utilizing capability as the receptor of SARS-CoV-2
Open accessAbstract
SARS-CoV-2, the newly identified human coronavirus causing severe pneumonia pandemic, was probably originated from Chinese horseshoe bats. However, direct transmission of the virus from bats to humans is unlikely due to lack of direct contact, implying the existence of unknown intermediate hosts. Angiotensin converting enzyme 2 (ACE2) is the receptor of SARS-CoV-2, but only ACE2s of certain species can be utilized by SARS-CoV-2. Here, we evaluated and ranked the receptor-utilizing capability of ACE2s from various species by phylogenetic clustering and sequence alignment with the currently known ACE2s utilized by SARS-CoV-2. As a result, we predicted that SARS-CoV-2 tends to utilize ACE2s of various mammals, except murines, and some birds, such as pigeon. This prediction may help to screen the intermediate hosts of SARS-CoV-2.
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A new coronavirus associated with human respiratory disease in China
Wu, F., Zhao, S., Yu, B., Chen, Y.-M., Wang, W., Song, Z.-G., Hu, Y., Tao, Z.-W., Tian, J.-H., Pei, Y.-Y., et al. (2020) · Nature · doi:10.1038/s41586-020-2008-3 · Cited by 11,688
Self-citationWan, Y., Shang, J., Graham, R., Baric, R. S., & Li, F. (2020) · Journal of Virology · doi:10.1128/jvi.00127-20 · Cited by 4,341 · cited 1×
“Among these sites, K31D, Y41A, Y83F, K353 H/A/D, D355A and R357A abolish or strongly inhibit SARS-CoV binding, while the substitutions on K68 and M383 slightly inhibit SARS-CoV binding [14,15].”
A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus–induced lung injury
Kuba, K., Imai, Y., Rao, S., Gao, H., Guo, F., Guan, B., Huan, Y., Yang, P., Zhang, Y., Deng, W., et al. (2005) · Nature Medicine · doi:10.1038/nm1267 · Cited by 3,445
Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor
Ge, X.-Y., Li, J.-L., Yang, X.-L., Chmura, A. A., Zhu, G., Epstein, J. H., Mazet, J. K., Hu, B., Zhang, W., Peng, C., et al. (2013) · Nature · doi:10.1038/nature12711 · Cited by 1,778
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Cited by
Damas, J., Hughes, G. M., Keough, K. C., Painter, C. A., Persky, N. S., Corbo, M., Hiller, M., Koepfli, K.-P., Pfenning, A. R., Zhao, H., et al. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2010146117 · Cited by 633
A Guide to COVID‐19: a global pandemic caused by the novel coronavirus SARS‐CoV‐2
Atzrodt, C. L., Maknojia, I., McCarthy, R. D. P., Oldfield, T. M., Po, J., Ta, K. T. L., Stepp, H. E., & Clements, T. P. (2020) · The FEBS Journal · doi:10.1111/febs.15375 · Cited by 341
Emergence of bat-related betacoronaviruses: hazard and risks
Frutos, R., Serra-Cobo, J., Pinault, L., Lopez Roig, M., & Devaux, C. A. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.591535 · Cited by 66
Devaux, C. A., & Camoin-Jau, L. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.1042200 · Cited by 20
Kamel, M. S., El-Sayed, A. A., Munds, R. A., & Verma, M. S. (2023) · Animals · doi:10.3390/ani13030524 · Cited by 12
Metadata
- Authors
- Qiu, Y., Zhao, Y.-B., Wang, Q., Li, J.-Y., Zhou, Z.-J., Liao, C.-H., & Ge, X.-Y.
- Venue
- Microbes and Infection
- Publisher
- Elsevier BV
- Published
- 2020-05
- Volume
- 22
- Issue
- 4-5
- Pages
- 221-225
- ISSN
- 1286-4579 (ISSN-L)
- OpenAlex
- W3010763499
- Cited by
- 216
- References
- 4
- FWCI
- 6.04
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Qiu, Y., Zhao, Y.-B., Wang, Q., Li, J.-Y., Zhou, Z.-J., Liao, C.-H., & Ge, X.-Y. (2020). Predicting the angiotensin converting enzyme 2 (ACE2) utilizing capability as the receptor of SARS-CoV-2. Microbes and Infection. https://doi.org/10.1016/j.micinf.2020.03.003
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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