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Antialgal, antibacterial and antifungal activity of two metabolites produced and excreted by cyanobacteria during growth
Open accessAbstract
The antimicrobial activity of two cyanobacterial exometabolites, norharmane (9H-pyrido(3,4-b)indole) and 4,4'-dihydroxybiphenyl, was determined in suspension assays. Good anticyanobacterial activities (concentrations of 8-80 microg ml(-1)) and moderate antibacterial (16-160 microg ml(-1)) and antifungal (32-40 microg ml(-1)) activities were found for both compounds. The natural function as allelopathic chemicals and a possible applicability as antifouling agents or leads for the development of new antifouling chemicals are discussed.
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“These toxic substances also have important antibacterial and antifungal activities [211, 212].”
From The promising future of microalgae: Current status, challenges, and optimization of a sustainable and renewable industry for biofuels, feed, and other products (2018) · cites this paper as [212]
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“Some microalgae also produce compounds that have antifungal activities [212].”
From The promising future of microalgae: Current status, challenges, and optimization of a sustainable and renewable industry for biofuels, feed, and other products (2018) · cites this paper as [212]
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Metadata
- Authors
- Volk, R.-B., & Furkert, F. H.
- Affiliations
- Christian-Albrechts-Universität zu Kiel (DE)
- Corresponding author
- Volk, Rainer-B.
- Venue
- Microbiological Research
- Publisher
- Elsevier BV
- Published
- 2006-02
- Volume
- 161
- Issue
- 2
- Pages
- 180-186
- ISSN
- 0944-5013 (ISSN-L)
- OpenAlex
- W2002556492
- Cited by
- 247
- References
- 31
- Citations by year
- 2026: 5 · 2025: 10 · 2024: 11 · 2023: 15 · 2022: 13 · 2021: 20 · 2020: 19 · 2019: 14 · 2018: 16 · 2017: 18 · 2016: 11 · 2015: 13 · 2014: 12 · 2013: 12 · 2012: 9
- FWCI
- 19.08
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Microbiological Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Engineering › Ocean Engineering › Marine Biology and Environmental Chemistry
- Life Sciences › Immunology and Microbiology › Applied Microbiology and Biotechnology › Microbial Natural Products and Biosynthesis
- Physical Sciences › Environmental Science › Environmental Chemistry › Aquatic Ecosystems and Phytoplankton Dynamics
- Keywords
- norharman, 4,4'-biphenol, antialgal activity, antibacterial activity, antifungal activity, allelopathy, antifouling agents, natural products
- MeSH terms
- Cyanobacteria, Anti-Bacterial Agents, Antifungal Agents, Biphenyl Compounds, Carbolines, Harmine, Microbial Sensitivity Tests
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