A case of breakthrough Candida parapsilosis fungemia during micafungin therapy for a Candida glabrata bloodstream infection
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We describe a case of breakthrough Candida parapsilosis fungemia in an 80-year-old woman with pyoderma gangrenosum and rheumatoid arthritis. C. parapsilosis was detected in blood culture while the patient was treated with micafungin for a Candida glabrata bloodstream infection. The breakthrough infection was successfully treated with liposomal amphotericin B.
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Norimatsu et al. reported that liposomal amphotericin B (3 mg/kg/day) showed better activity than micafungin in the treatment of both C. glabrata and C. parapsilosis bloodstream infections in an 80-year-old woman.
“According to the findings reported by Norimatsu et al. [4], the liposomal AmB (3 mg/kg/day) showed better activity than micafungin in the treatment of both C. glabrata and C. parapsilosis bloodstream infections in the case of an 80-year-old woman.”
From Candida glabrata: pathogenicity and resistance mechanisms for adaptation and survival (2021) · cites this paper as [4]
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Candida parapsilosis: from genes to the bedside
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Candida glabrata: pathogenicity and resistance mechanisms for adaptation and survival
Hassan, Y., Chew, S. Y., & Than, L. T. L. (2021) · Journal of Fungi · doi:10.3390/jof7080667 · Cited by 170 · see citing works
- Authors
- Norimatsu, Y., Morii, D., Kogure, A., Hamanaka, T., Kuwano, Y., Yokozawa, T., & Oda, T.
- Affiliations
- Showa General Hospital (JP)
- Corresponding author
- Norimatsu, Yuta
- Venue
- Medical Mycology Case Reports
- Publisher
- Elsevier BV
- Published
- 2017-06
- Volume
- 16
- Pages
- 1-3
- ISSN
- 2211-7539 (ISSN-L)
- PMC
- PMC5369859
- OpenAlex
- W2602044155
- Cited by
- 8
- References
- 13
- Citations by year
- 2023: 1 · 2021: 3 · 2019: 1 · 2018: 1 · 2017: 2
- FWCI
- 0.84
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Medical Mycology Case Reports (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Institutional Repositories DataBase (IRDB) (submittedVersion, cc-by-nc-nd)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Health Sciences › Medicine › Epidemiology › Fungal Infections and Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Yeasts and Rust Fungi Studies
- Keywords
- Candida parapsilosis, Candida glabrata, micafungin, antifungal resistance, bloodstream infection, pyoderma gangrenosum, rheumatoid arthritis, liposomal amphotericin B, elderly patients
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