Candida parapsilosis: from genes to the bedside

RNA-Seq: a revolutionary tool for transcriptomics

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Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America

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International Study of the Prevalence and Outcomes of Infection in Intensive Care Units

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Evolution of pathogenicity and sexual reproduction in eight Candida genomes

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Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis

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Candidalysin is a fungal peptide toxin critical for mucosal infection

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Azole Antifungal Resistance in Candida albicans and Emerging Non-albicans Candida Species

Whaley, S. G., Berkow, E. L., Rybak, J. M., Nishimoto, A. T., Barker, K. S., & Rogers, P. D. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.02173 · Cited by 900 · see citing works

Potential Role of Phospholipases in Virulence and Fungal Pathogenesis

Ghannoum, M. A. (2000) · Clinical Microbiology Reviews · doi:10.1128/cmr.13.1.122-143.2000 · Cited by 814 · see citing works

Amphotericin B formulations: a comparative review of efficacy and toxicity

Hamill, R. J. (2013) · Drugs · doi:10.1007/s40265-013-0069-4 · Cited by 807 · see citing works

Genome-wide measurement of RNA secondary structure in yeast

Kertesz, M., Wan, Y., Mazor, E., Rinn, J. L., Nutter, R. C., Chang, H. Y., & Segal, E. (2010) · Nature · doi:10.1038/nature09322 · Cited by 765 · see citing works

Antifungal Susceptibility of Candida Biofilms: Unique Efficacy of Amphotericin B Lipid Formulations and Echinocandins

Kuhn, D. M., George, T., Chandra, J., Mukherjee, P. K., & Ghannoum, M. A. (2002) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.46.6.1773-1780.2002 · Cited by 765 · see citing works

Rapid Hypothesis Testing with Candida albicans through Gene Disruption with Short Homology Regions

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The SAT1 flipper, an optimized tool for gene disruption in Candida albicans

Reuß, O., Vik, Å., Kolter, R., & Morschhäuser, J. (2004) · Gene · doi:10.1016/j.gene.2004.06.021 · Cited by 744 · see citing works

Mechanism of NLRP3 inflammasome activation

Sutterwala, F. S., Haasken, S., & Cassel, S. L. (2014) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12458 · Cited by 736 · see citing works

A Recently Evolved Transcriptional Network Controls Biofilm Development in Candida albicans

Nobile, C. J., Fox, E. P., Nett, J. E., Sorrells, T. R., Mitrovich, Q. M., Hernday, A. D., Tuch, B. B., Andes, D. R., & Johnson, A. D. (2012) · Cell · doi:10.1016/j.cell.2011.10.048 · Cited by 711 · see citing works

Candida Biofilms: Threats, Challenges, and Promising Strategies

Cavalheiro, M., & Teixeira, M. C. (2018) · Frontiers in Medicine · doi:10.3389/fmed.2018.00028 · Cited by 690 · see citing works

RNA ‐Seq methods for transcriptome analysis

Hrdličková, R., Toloue, M., & Tian, B. (2016) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1364 · Cited by 686 · see citing works

Global trends in the distribution of Candida species causing candidemia

Guinea, J. (2014) · Clinical Microbiology and Infection · doi:10.1111/1469-0691.12539 · Cited by 680 · see citing works

Candida orthopsilosis and Candida metapsilosis spp. nov. To Replace Candida parapsilosis Groups II and III

Tavanti, A., Davidson, A. D., Gow, N. A. R., Maiden, M. C. J., & Odds, F. C. (2005) · Journal of Clinical Microbiology · doi:10.1128/jcm.43.1.284-292.2005 · Cited by 593 · see citing works

Yeast-enhanced green fluorescent protein (yEGFP): a reporter of gene expression in Candida albicans

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Strains and Strategies for Large-Scale Gene Deletion Studies of the Diploid Human Fungal Pathogen <i>Candida albicans</i>

Noble, S. M., & Johnson, A. D. (2005) · Eukaryotic Cell · doi:10.1128/ec.4.2.298-309.2005 · Cited by 592 · see citing works

Liposomal Amphotericin B (AmBisome®): A Review of the Pharmacokinetics, Pharmacodynamics, Clinical Experience and Future Directions

Stone, N. R. H., Bicanic, T., Salim, R., & Hope, W. (2016) · Drugs · doi:10.1007/s40265-016-0538-7 · Cited by 537 · see citing works

Epidemiology, management, and risk factors for death of invasive Candida infections in critical care: A multicenter, prospective, observational study in France (2005–2006)

Leroy, O., Gangneux, J., Montravers, P., Mira, J. P., Gouin, F., Sollet, J.-P., Carlet, J. M., Reynes, J., Rosenheim, M., Regnier, B., et al. (2009) · Critical Care Medicine · doi:10.1097/ccm.0b013e31819efac0 · Cited by 536 · see citing works

Large‐scale essential gene identification in Candida albicans and applications to antifungal drug discovery

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Mechanism of Fluconazole Resistance in <i>Candida albicans</i> Biofilms: Phase-Specific Role of Efflux Pumps and Membrane Sterols

Mukherjee, P. K., Chandra, J., Kuhn, D. M., & Ghannoum, M. A. (2003) · Infection and Immunity · doi:10.1128/iai.71.8.4333-4340.2003 · Cited by 511 · see citing works

Antifungal Susceptibility Survey of 2,000 Bloodstream Candida Isolates in the United States

Ostrosky‐Zeichner, L., Rex, J. H., Pappas, P. G., Hamill, R. J., Larsen, R. A., Horowitz, H. W., Powderly, W. G., Hyslop, N. E., Kauffman, C. A., Cleary, J. D., et al. (2003) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.47.10.3149-3154.2003 · Cited by 494 · see citing works

Comparison of Biofilms Formed byCandidaalbicansandCandidaparapsilosison Bioprosthetic Surfaces

Kuhn, D. M., Chandra, J., Mukherjee, P. K., & Ghannoum, M. A. (2002) · Infection and Immunity · doi:10.1128/iai.70.2.878-888.2002 · Cited by 485 · see citing works

Prevalence of Molecular Mechanisms of Resistance to Azole Antifungal Agents in <i>Candida albicans</i> Strains Displaying High-Level Fluconazole Resistance Isolated from Human Immunodeficiency Virus-Infected Patients

Perea, S., López-Ribot, J. L., Kirkpatrick, W. R., McAtee, R. K., Santillán, R. A., Martı́nez, M., Calabrese, D., Sanglard, D., & Patterson, T. F. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.10.2676-2684.2001 · Cited by 470 · see citing works

The<i>Candida</i>Genome Database (CGD): incorporation of Assembly 22, systematic identifiers and visualization of high throughput sequencing data

Skrzypek, M. S., Binkley, J., Binkley, G., Miyasato, S. R., Simison, M., & Sherlock, G. (2017) · Nucleic Acids Research · doi:10.1093/nar/gkw924 · Cited by 455 · see citing works

Incidence, characteristics and outcome of ICU-acquired candidemia in India

Chakrabarti, A., Sood, P., Rudramurthy, S. M., Chen, S., Kaur, H., Capoor, M., Chhina, D., Rao, R., Eshwara, V. K., Xess, I., et al. (2015) · Intensive Care Medicine · doi:10.1007/s00134-014-3603-2 · Cited by 454 · see citing works

Characteristics and determinants of outcome of hospital-acquired bloodstream infections in intensive care units: the EUROBACT International Cohort Study

Tabah, A., Koulenti, D., Laupland, K. B., Misset, B., Vallés, J., de Carvalho, F. B., Paiva, J. A., Çakar, N., Ma, X., Eggimann, P., et al. (2012) · Intensive Care Medicine · doi:10.1007/s00134-012-2695-9 · Cited by 436 · see citing works

Putative Role of β-1,3 Glucans in <i>Candida albicans</i> Biofilm Resistance

Nett, J., Lincoln, L., Marchillo, K., Massey, R., Holoyda, K., Hoff, B., VanHandel, M., & Andes, D. (2007) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01056-06 · Cited by 407 · see citing works

<i>TAC1</i> , Transcriptional Activator of <i>CDR</i> Genes, Is a New Transcription Factor Involved in the Regulation of <i>Candida albicans</i> ABC Transporters <i>CDR1</i> and <i>CDR2</i>

Coste, A. T., Karababa, M., Ischer, F., Bille, J., & Sanglard, D. (2004) · Eukaryotic Cell · doi:10.1128/ec.3.6.1639-1652.2004 · Cited by 407 · see citing works

Susceptibilities of Candida albicans multidrug transporter mutants to various antifungal agents and other metabolic inhibitors

Sanglard, D., Ischer, F., Monod, M., & Billé, J. (1996) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.40.10.2300 · Cited by 402 · see citing works

Epidemiology and Outcomes of Invasive Candidiasis Due to Non-albicans Species of Candida in 2,496 Patients: Data from the Prospective Antifungal Therapy (PATH) Registry 2004–2008

Pfaller, M. A., Andes, D. R., Diekema, D. J., Horn, D. L., Reboli, A. C., Rotstein, C., Franks, B., & Azie, N. E. (2014) · PLoS ONE · doi:10.1371/journal.pone.0101510 · Cited by 396 · see citing works

Biofilms of non-<i>Candida albicans Candida</i>species: quantification, structure and matrix composition

Silva, S., Henriques, M., Martins, A., Oliveira, R., Williams, D., & Azeredo, J. (2009) · Medical Mycology · doi:10.3109/13693780802549594 · Cited by 390 · see citing works

In Vitro Susceptibility of Invasive Isolates of Candida spp. to Anidulafungin, Caspofungin, and Micafungin: Six Years of Global Surveillance

Pfaller, M. A., Boyken, L. B., Hollis, R. J., Kroeger, J. S., Messer, S. A., Tendolkar, S., & Diekema, D. J. (2007) · Journal of Clinical Microbiology · doi:10.1128/jcm.01901-07 · Cited by 389 · see citing works

Neonatal Candidiasis: Epidemiology, Risk Factors, and Clinical Judgment

Benjamin, D. K., Stoll, B. J., Gantz, M. G., Walsh, M. C., Sánchez, P. J., Das, A., Shankaran, S., Higgins, R. D., Auten, K. J., Miller, N. A., et al. (2010) · PEDIATRICS · doi:10.1542/peds.2009-3412 · Cited by 380 · see citing works

Epidemiology of candidemia in Latin America: a laboratory-based survey

Nucci, M., Queiroz-Telles, F., Alvarado-Matute, T., Tiraboschi, I. N., Cortes, J., Zurita, J., Guzman-Blanco, M., Santolaya, M. E., Thompson, L., Sifuentes-Osornio, J., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0059373 · Cited by 374 · see citing works

Echinocandin resistance in Candida.

Perlin, D. S. (2015) · Clinical Infectious Diseases · doi:10.1093/cid/civ791 · Cited by 374 · see citing works

Results from the ARTEMIS DISK Global Antifungal Surveillance Study, 1997 to 2007: 10.5-Year Analysis of Susceptibilities of Noncandidal Yeast Species to Fluconazole and Voriconazole Determined by CLSI Standardized Disk Diffusion Testing

Pfaller, M. A., Diekema, D. J., Gibbs, D. L., Newell, V. A., Hu, B., Dzierzanowska, D., Климко, Н. Н., Letscher‐Bru, V., Lisalová, M., Muehlethaler, K., et al. (2008) · Journal of Clinical Microbiology · doi:10.1128/jcm.01747-08 · Cited by 370 · see citing works

A Candida albicans CRISPR system permits genetic engineering of essential genes and gene families

Vyas, V. K., Barrasa, M. I., & Fink, G. R. (2015) · Science Advances · doi:10.1126/sciadv.1500248 · Cited by 363 · see citing works

Th17 cells in immunity to Candida albicans

Hernández-Santos, N., & Gaffen, S. L. (2012) · Cell Host &amp; Microbe · doi:10.1016/j.chom.2012.04.008 · Cited by 361 · see citing works

The Transcription Factor Mrr1p Controls Expression of the MDR1 Efflux Pump and Mediates Multidrug Resistance in Candida albicans

Morschhäuser, J., Barker, K. S., Liu, T. T., Blaß-Warmuth, J., Homayouni, R., & Rogers, P. D. (2007) · PLoS Pathogens · doi:10.1371/journal.ppat.0030164 · Cited by 355 · see citing works

MAPK, MKP1 and c-Fos Discriminate Candida albicans Yeast from Hyphae in Epithelial Cells

Moyes, D., Runglall, M., Murciano, C., Shen, C., Nayar, D., Thavaraj, S., Kohli, A., Islam, A., Mora-Montes, H., Challacombe, S., et al. (2010) · Cell Host and Microbe · doi:10.1016/j.chom.2010.08.002 · Cited by 347 · see citing works

Biofilm Production by <i>Candida</i> Species and Inadequate Antifungal Therapy as Predictors of Mortality for Patients with Candidemia

Tumbarello, M., Posteraro, B., Trecarichi, E. M., Fiori, B., Rossi, M., Porta, R., de Gaetano Donati, K., La Sorda, M., Spanu, T., Fadda, G., et al. (2007) · Journal of Clinical Microbiology · doi:10.1128/jcm.00131-07 · Cited by 343 · see citing works

A Naturally Occurring Proline-to-Alanine Amino Acid Change in Fks1p in <i>Candida parapsilosis</i> , <i>Candida orthopsilosis</i> , and <i>Candida metapsilosis</i> Accounts for Reduced Echinocandin Susceptibility

Garcia-Effron, G., Katiyar, S. K., Park, S., Edlind, T. D., & Perlin, D. S. (2008) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00262-08 · Cited by 323 · see citing works

Biofilm lifestyle of <i>Candida:</i> a mini review

Seneviratne, C., Jin, L., & Samaranayake, L. (2008) · Oral Diseases · doi:10.1111/j.1601-0825.2007.01424.x · Cited by 317 · see citing works

Immune Recognition of <i>Candida albicans</i> β‐glucan by Dectin‐1

Gow, N. A. R., Netea, M. G., Munro, C. A., Ferwerda, G., Bates, S., Mora‐Montes, H. M., Walker, L., Jansen, T., Jacobs, L., Tsoni, V., et al. (2007) · The Journal of Infectious Diseases · doi:10.1086/523110 · Cited by 314 · see citing works

Expulsion of Live Pathogenic Yeast by Macrophages

Ma, H., Croudace, J. E., Lammas, D. A., & May, R. C. (2006) · Current Biology · doi:10.1016/j.cub.2006.09.032 · Cited by 310 · see citing works

Candida Species Biofilms’ Antifungal Resistance

Silva, S. M., Rodrigues, C. F., Araújo, D., Rodrigues, M. E., & Henriques, M. (2017) · Journal of Fungi · doi:10.3390/jof3010008 · Cited by 308 · see citing works

Species identification and antifungal susceptibility testing of Candida bloodstream isolates from population-based surveillance studies in two U.S. cities from 2008 to 2011.

Lockhart, S. R., Iqbal, N., Cleveland, A. A., Farley, M. M., Harrison, L. H., Bolden, C. B., Baughman, W., Stein, B., Hollick, R., Park, B. J., et al. (2012) · Journal of Clinical Microbiology · doi:10.1128/jcm.01283-12 · Cited by 299 · see citing works

Epidemiology and predictive factors for early and late mortality in Candida bloodstream infections: a population-based surveillance in Spain

Puig‐Asensio, M., Padilla, B., Garnacho‐Montero, J., Zaragoza, Ó., Aguado, J. M., Zaragoza, R., Montejo, M., Muñóz, P., Ruíz-Camps, I., Cuenca‐Estrella, M., et al. (2013) · Clinical Microbiology and Infection · doi:10.1111/1469-0691.12380 · Cited by 297 · see citing works

Predictors of Adverse Outcome in Cancer Patients with Candidemia

Anaissie, E. J., Rex, J. H., Uzun, Ö., & Vartivarian, S. (1998) · The American Journal of Medicine · doi:10.1016/s0002-9343(98)00030-8 · Cited by 295 · see citing works

Nosocomial bloodstream infections due to Candida spp. in the USA: species distribution, clinical features and antifungal susceptibilities

Wisplinghoff, H., Ebbers, J., Geurtz, L., Stefanik, D., Major, Y., Edmond, M. B., Wenzel, R. P., & Seifert, H. (2014) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2013.09.005 · Cited by 293 · see citing works

Results from the ARTEMIS DISK Global Antifungal Surveillance Study, 1997 to 2005: an 8.5-Year Analysis of Susceptibilities of Candida Species and Other Yeast Species to Fluconazole and Voriconazole Determined by CLSI Standardized Disk Diffusion Testing

Pfaller, M. A., Diekema, D. J., Gibbs, D. L., Newell, V. A., Meis, J. F. G. M., Gould, I. M., Fu, W., Colombo, A. L., & Rodríguez-Noriega, E. (2007) · Journal of Clinical Microbiology · doi:10.1128/jcm.00409-07 · Cited by 287 · see citing works

The ‘obligate diploid’ Candida albicans forms mating-competent haploids

Hickman, M. A., Zeng, G., Forche, A., Hirakawa, M. P., Abbey, D., Harrison, B. D., Wang, Y.-M., Su, C.-H., Bennett, R. J., Wang, Y., et al. (2013) · Nature · doi:10.1038/nature11865 · Cited by 284 · see citing works

International Surveillance of Bloodstream Infections Due to <i>Candida</i> Species: Frequency of Occurrence and Antifungal Susceptibilities of Isolates Collected in 1997 in the United States, Canada, and South America for the SENTRY Program

Pfaller, M. A., Jones, R. N., Doern, G. V., Sader, H. S., Hollis, R. J., Messer, S. A., & Group, F. T. S. P. (1998) · Journal of Clinical Microbiology · doi:10.1128/jcm.36.7.1886-1889.1998 · Cited by 281 · see citing works

Ectopic Expression of URA3 Can Influence the Virulence Phenotypes and Proteome of Candida albicans but Can Be Overcome by Targeted Reintegration of URA3 at the RPS10 Locus

Brand, A., MacCallum, D. M., Brown, A. J. P., Gow, N. A. R., & Odds, F. C. (2004) · Eukaryotic Cell · doi:10.1128/ec.3.4.900-909.2004 · Cited by 272 · see citing works

Candidemia in patients with hematologic malignancies in the era of new antifungal agents (2001‐2007): Stable incidence but changing epidemiology of a still frequently lethal infection

Sipsas, N. V., Lewis, R. E., Tarrand, J., Hachem, R., Rolston, K. V., Raad, I. I., & Kontoyiannis, D. P. (2009) · Cancer · doi:10.1002/cncr.24507 · Cited by 269 · see citing works

Dimorphism and virulence in Candida albicans

Mitchell, A. P. (1998) · Current Opinion in Microbiology · doi:10.1016/s1369-5274(98)80116-1 · Cited by 256 · see citing works

Capsule enlargement in Cryptococcus neoformans confers resistance to oxidative stress suggesting a mechanism for intracellular survival

Zaragoza, Ó., Chrisman, C. J., Castelli, M. V., Frasés, S., Cuenca‐Estrella, M., Rodrı́guez-Tudela, J. L., & Casadevall, A. (2008) · Cellular Microbiology · doi:10.1111/j.1462-5822.2008.01186.x · Cited by 252 · see citing works

Pathogenic Yeasts Cryptococcus neoformans and Candida albicans Produce Immunomodulatory Prostaglandins

Noverr, M. C., Phare, S. M., Toews, G. B., Coffey, M., & Huffnagle, G. B. (2001) · Infection and Immunity · doi:10.1128/iai.69.5.2957-2963.2001 · Cited by 250 · see citing works

Candida albicans Gene Deletion with a Transient CRISPR-Cas9 System

Min, K., Ichikawa, Y., Woolford, C. A., & Mitchell, A. P. (2016) · mSphere · doi:10.1128/msphere.00130-16 · Cited by 246 · see citing works

Epidemiology, Risk Factors, and Prognosis of Candida parapsilosis Bloodstream Infections: Case-Control Population-Based Surveillance Study of Patients in Barcelona, Spain, from 2002 to 2003

Almirante, B., Rodríguez-Pardo, D., Cuenca‐Estrella, M., Almela, M., Sánchez, F., Ayats, J., Alonso-Tarrés, C., Rodrı́guez-Tudela, J. L., Pahissa, A., & the Barcelona Candidemia Project Study Group (2006) · Journal of Clinical Microbiology · doi:10.1128/jcm.44.5.1681-1685.2006 · Cited by 241 · see citing works

Gain-of-Function Mutations in <i>UPC2</i> Are a Frequent Cause of <i>ERG11</i> Upregulation in Azole-Resistant Clinical Isolates of Candida albicans

Flowers, S. A., Barker, K. S., Berkow, E. L., Toner, G., Chadwick, S. G., Gygax, S. E., Morschhäuser, J., & Rogers, P. D. (2012) · Eukaryotic Cell · doi:10.1128/ec.00215-12 · Cited by 239 · cited 1× · see citing works

<i>Candida</i> Bloodstream Infections: Comparison of Species Distributions and Antifungal Resistance Patterns in Community-Onset and Nosocomial Isolates in the SENTRY Antimicrobial Surveillance Program, 2008-2009

Pfaller, M. A., Moet, G. J., Messer, S. A., Jones, R. N., & Castanheira, M. (2011) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01079-10 · Cited by 238 · see citing works

<i>Candida albicans</i> Zinc Cluster Protein Upc2p Confers Resistance to Antifungal Drugs and Is an Activator of Ergosterol Biosynthetic Genes

MacPherson, S., Akache, B., Weber, S., De Deken, X., Raymond, M., & Turcotte, B. (2005) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.49.5.1745-1752.2005 · Cited by 238 · see citing works

Outer Chain N-Glycans Are Required for Cell Wall Integrity and Virulence of Candida albicans

Bates, S., Hughes, H. B., Munro, C. A., Thomas, W. P. H., MacCallum, D. M., Bertram, G., Atrih, A., Ferguson, M. A. J., Brown, A. J. P., Odds, F. C., et al. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m510360200 · Cited by 238 · see citing works

Platelet Count and Sepsis in Very Low Birth Weight Neonates: Is There an Organism-Specific Response?

Guida, J. D., Kunig, A. M., Leef, K. H., McKenzie, S. E., & Paul, D. A. (2003) · PEDIATRICS · doi:10.1542/peds.111.6.1411 · Cited by 237 · see citing works

Preclinical Assessment of the Efficacy of Mycograb, a Human Recombinant Antibody against Fungal HSP90

Matthews, R., Rigg, G. P., Hodgetts, S. J., Carter, T., Chapman, C. J., Gregory, C. A., Illidge, C., & Burnie, J. (2003) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.47.7.2208-2216.2003 · Cited by 232 · see citing works

Geographic Variations in Species Distribution and Echinocandin and Azole Antifungal Resistance Rates among Candida Bloodstream Infection Isolates: Report from the SENTRY Antimicrobial Surveillance Program (2008 to 2009)

Pfaller, M. A., Moet, G. J., Messer, S. A., Jones, R. N., & Castanheira, M. (2010) · Journal of Clinical Microbiology · doi:10.1128/jcm.01398-10 · Cited by 228 · see citing works

Results from the ARTEMIS DISK Global AntifungalSurveillance Study: a 6.5-Year Analysis of Susceptibilitiesof <i>Candida</i> and Other Yeast Species to Fluconazole andVoriconazole by Standardized Disk Diffusion Testing

Pfaller, M. A., Diekema, D. J., Rinaldi, M. G., Barnes, R., Hu, B., Veselov, A. V., Tiraboschi, N., Nagy, E., & Gibbs, D. L. (2005) · Journal of Clinical Microbiology · doi:10.1128/jcm.43.12.5848-5859.2005 · Cited by 228 · see citing works

Candida albicans Triggers NLRP3-Mediated Pyroptosis in Macrophages

Wellington, M., Koselny, K., Sutterwala, F. S., & Krysan, D. J. (2014) · Eukaryotic Cell · doi:10.1128/ec.00336-13 · Cited by 227 · see citing works

<i>In Vivo</i> Comparison of the Pharmacodynamic Targets for Echinocandin Drugs against <i>Candida</i> Species

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National Surveillance of Fungemia in Denmark (2004 to 2009)

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COVID-19-Associated Pulmonary Aspergillosis, Fungemia, and Pneumocystosis in the Intensive Care Unit: a Retrospective Multicenter Observational Cohort during the First French Pandemic Wave

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Determinants of fluconazole resistance and echinocandin tolerance in C. parapsilosis isolates causing a large clonal candidemia outbreak among COVID-19 patients in a Brazilian ICU

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Candida parapsilosis : A systematic review to inform the World Health Organization fungal priority pathogens list

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Triazole Evolution of Candida parapsilosis Results in Cross-Resistance to Other Antifungal Drugs, Influences Stress Responses, and Alters Virulence in an Antifungal Drug-Dependent Manner

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Opportunistic yeast pathogen Candida spp.: Secreted and membrane-bound virulence factors.

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Emergence of resistantCandida glabratain Germany

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Recent Increase in the Prevalence of Fluconazole-Non-susceptible Candida tropicalis Blood Isolates in Turkey: Clinical Implication of Azole-Non-susceptible and Fluconazole Tolerant Phenotypes and Genotyping

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The Candida Genome Database: annotation and visualization updates

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Early Virulence Predictors during the Candida Species–Galleria mellonella Interaction

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Metagenomic profiling of hospital wastewater: A comprehensive national scale analysis of antimicrobial resistance genes and opportunistic pathogens

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Candida parapsilosis Mdr1B and Cdr1B Are Drivers of Mrr1-Mediated Clinical Fluconazole Resistance

Doorley, L. A., Rybak, J. M., Berkow, E. L., Zhang, Q. H., Morschhäuser, J., & Rogers, P. D. (2022) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00289-22 · Cited by 34 · see citing works

Candida blood stream infections observed between 2011 and 2016 in a large Italian University Hospital: A time-based retrospective analysis on epidemiology, biofilm production, antifungal agents consumption and drug-susceptibility

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Species distribution, azole resistance and related molecular mechanisms in invasive Candida parapsilosis complex isolates: Increase in fluconazole resistance in 21 years

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Metagenomic Investigation of Ticks From Kenyan Wildlife Reveals Diverse Microbial Pathogens and New Country Pathogen Records

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Pan-Echinocandin Resistant C. parapsilosis Harboring an F652S Fks1 Alteration in a Patient with Prolonged Echinocandin Therapy

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Candida spp. in Human Intestinal Health and Disease: More than a Gut Feeling

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Genomic reconstruction of an azole-resistant Candida parapsilosis outbreak and the creation of a multi-locus sequence typing scheme: a retrospective observational and genomic epidemiology study

Brassington, P. J. T., Klefisch, F.-R., Graf, B., Pfüller, R., Kurzai, O., Walther, G., & Barber, A. E. (2024) · The Lancet Microbe · doi:10.1016/j.lanmic.2024.07.012 · Cited by 35 · see citing works

Candida Pathogenicity and Interplay with the Immune System

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Tracing the Origin of Invasive Fungal Infections

Papon, N., Bougnoux, M., & d’Enfert, C. (2020) · Trends in Microbiology · doi:10.1016/j.tim.2020.01.007 · Cited by 33 · see citing works

Genotyping Reveals High Clonal Diversity and Widespread Genotypes of Candida Causing Candidemia at Distant Geographical Areas

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Candida Empyema Thoracis at Two Academic Medical Centers: New Insights Into Treatment and Outcomes

Senger, S. S., Thompson, G. R., Samanta, P., Ahrens, J., Clancy, C. J., & Nguyen, M. H. (2021) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofaa656 · Cited by 33 · see citing works

Physiological and Transcriptional Responses of Candida parapsilosis to Exogenous Tyrosol

Jakab, Á., Tóth, Z., Nagy, F., Nemes, D., Bácskay, I., Kardos, G., Emri, T., Pócsi, I., Majoros, L., & Kovács, R. (2019) · Applied and Environmental Microbiology · doi:10.1128/aem.01388-19 · Cited by 32 · see citing works

Antifungal and Antibiofilm Activity of Cyclic Temporin L Peptide Analogues against Albicans and Non-Albicans Candida Species

Bellavita, R., Maione, A., Merlino, F., Siciliano, A., Dardano, P., Stefano, L. D., Galdiero, S., Galdiero, E., Grieco, P., & Falanga, A. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14020454 · Cited by 31 · see citing works

Paradigm Shift: Candida parapsilosis sensu stricto as the Most Prevalent Candida Species Isolated from Bloodstream Infections with Increasing Azole-Non-Susceptibility Rates: Trends from 2015–2022 Survey

Franconi, I., Rizzato, C., Tavanti, A., Falcone, M., & Lupetti, A. (2023) · Journal of Fungi · doi:10.3390/jof9101012 · Cited by 31 · see citing works

Moonlighting proteins in medically relevant fungi

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Distribution, trends, and antifungal susceptibility of<i>Candida</i>species causing candidemia in Japan, 2010–2019: A retrospective observational study based on national surveillance data

Kajihara, T., Yahara, K., Nagi, M., Kitamura, N., Hirabayashi, A., Hosaka, Y., Abe, M., Miyazaki, Y., & Sugai, M. (2022) · Medical Mycology · doi:10.1093/mmy/myac071 · Cited by 29 · see citing works

Iron Metabolism, Pseudohypha Production, and Biofilm Formation through a Multicopper Oxidase in the Human-Pathogenic Fungus Candida parapsilosis

Chakraborty, T., Tóth, Z., Tóth, R., Vágvölgyi, C., & Gácser, A. (2020) · mSphere · doi:10.1128/msphere.00227-20 · Cited by 28 · see citing works

High colonization by Candida parapsilosis sensu stricto on hands and surfaces in an adult intensive care unit

da Silva, E. M., Mansano, E. S. B., Mendonca, P., Olegário, R., Tobaldini-Valério, F. K., Fiorini, A., & Svidzinski, T. I. E. (2021) · Journal de Mycologie Médicale · doi:10.1016/j.mycmed.2020.101110 · Cited by 28 · see citing works

Evaluation of Autof MS 1000 and Vitek MS MALDI-TOF MS System in Identification of Closely-Related Yeasts Causing Invasive Fungal Diseases

Yi, Q., Xiao, M., Fan, X., Zhang, G., Yang, Y., Zhang, J., Duan, S., Cheng, J., Li, Y., Zhou, M., et al. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2021.628828 · Cited by 27 · see citing works

How does temperature trigger biofilm adhesion and growth in Candida albicans and two non‐Candida albicans Candida species?

Pierantoni, D. C., Corte, L., Casadevall, A., Robert, V., Cardinali, G., & Tascini, C. (2021) · Mycoses · doi:10.1111/myc.13291 · Cited by 28 · see citing works

Aneuploidy Underlies Tolerance and Cross-Tolerance to Drugs in Candida parapsilosis

Yang, F. J., Lu, H., Wu, H., Fang, T., Berman, J. G., & Jiang, Y. (2021) · Microbiology Spectrum · doi:10.1128/spectrum.00508-21 · Cited by 27 · see citing works

Antifungal Effect and Inhibition of the Virulence Mechanism of D-Limonene against Candida parapsilosis

de Andrade, M. C. L., Neto, L. N. D. A., Buonafina, M. D. S., dos Santos, F. D. A. G., Alves, A. I. D. S., de Castro, M. C. A. B., Mori, E., de Lacerda, B. C. G. V., Araújo, I. M., Coutinho, H. D. M., et al. (2022) · Molecules · doi:10.3390/molecules27248884 · Cited by 27 · see citing works

Glucose - The X factor for the survival of human fungal pathogens and disease progression in the host

Qadri, H., Qureshi, M. F., Mir, M. A., & Shah, A. H. (2021) · Microbiological Research · doi:10.1016/j.micres.2021.126725 · Cited by 27 · see citing works

Impact of Fluconazole Resistance on the Outcomes of Patients With Candida parapsilosis Bloodstream Infections: A Retrospective Multicenter Study

Vena, A., Tiseo, G., Falcone, M., Bartalucci, C., Marelli, C., Cesaretti, M., Pilato, V. D., Escribano, P., Forniti, A., Giacobbe, D. R., et al. (2025) · Clinical Infectious Diseases · doi:10.1093/cid/ciae603 · Cited by 26 · see citing works

Prevalence and Antifungal Susceptibility of Candida parapsilosis Species Complex in Eastern China: A 15-Year Retrospective Study by ECIFIG

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Candida parapsilosis Sensu Stricto Antifungal Resistance Mechanisms and Associated Epidemiology

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Clinical azole cross-resistance in Candida parapsilosis is related to a novel MRR1 gain-of-function mutation

Branco, J., Ryan, A. P., Silva, A. P., Butler, G., Miranda, I. M., & Rodrigues, A. G. (2022) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2022.08.014 · Cited by 25 · see citing works

Molecular Characterization of Candida parapsilosis by Microsatellite Typing and Emergence of Clonal Antifungal Drug Resistant Strains in a Multicenter Surveillance in China

Zhang, L., Yu, S.-Y., Chen, S. C.-A., Xiao, M., Kong, F., Wang, H., Ning, Y., Lu, M., Sun, T., Hou, X., et al. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.01320 · Cited by 24 · see citing works

Mutations in TAC1 and ERG11 are major drivers of triazole antifungal resistance in clinical isolates of Candida parapsilosis

Doorley, L. A., Barker, K. S., Zhang, Q., Rybak, J. M., & Rogers, P. D. (2023) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2023.08.030 · Cited by 23 · see citing works

Toxic, Radical Scavenging, and Antifungal Activity of Rhododendron tomentosum H. Essential Oils

Judžentienė, A., Būdienė, J., Švedienė, J., & Garjonytė, R. (2020) · Molecules · doi:10.3390/molecules25071676 · Cited by 23 · see citing works

Persistent candidemia caused by different Candida species: Data from a multicenter contemporary cohort

Tiseo, G., Vena, A., Bassetti, M., Bartalucci, C., Cerchiaro, M., Cesaretti, M., Marchese, A. E., Pilato, V. D., Escribano, P., Forniti, A., et al. (2025) · Journal of Infection · doi:10.1016/j.jinf.2025.106586 · Cited by 22 · see citing works

Synthesis, Structure, and Activity of the Antifungal Plant Defensin PvD1

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Molecular and Epidemiological Investigation of Fluconazole-resistant Candida parapsilosis —Georgia, United States, 2021

Misas, E., Witt, L. S., Farley, M. M., Thomas, S., Jenkins, E. N., Gade, L., Peterson, J. G., Restrepo, A. M., Fridkin, S. K., Lockhart, S. R., et al. (2024) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofae264 · Cited by 22 · see citing works

Candida parapsilosis Colony Morphotype Forecasts Biofilm Formation of Clinical Isolates

Gómez-Molero, E., De-la-Pinta, I., Fernández-Pereira, J., Groß, U., Weig, M., Quindós, G., de Groot, P. W. J., & Bader, O. (2021) · Journal of Fungi · doi:10.3390/jof7010033 · Cited by 21 · see citing works

Biochemical and structural characterization of enzymes in the 4-hydroxybenzoate catabolic pathway of lignin-degrading white-rot fungi

Kuatsjah, E., Schwartz, A., Zahn, M., Tornesakis, K., Kellermyer, Z. A., Ingraham, M. A., Woodworth, S. P., Ramirez, K. J., Cox, P. A., Pickford, A. R., et al. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.115002 · Cited by 20 · see citing works

First Canadian report of transmission of fluconazole-resistant Candida parapsilosis within two hospital networks confirmed by genomic analysis

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Intravital Imaging Reveals Divergent Cytokine and Cellular Immune Responses to Candida albicans and Candida parapsilosis

Archambault, L. S., Trzilova, D., Gonia, S., Gale, C. A., & Wheeler, R. T. (2019) · mBio · doi:10.1128/mbio.00266-19 · Cited by 19 · see citing works

Characterisation of Candida parapsilosis CYP51 as a Drug Target Using Saccharomyces cerevisiae as Host

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Voriconazole-Natural Latex Dressings for Treating Infected Candida Spp. Skin Ulcers

da Silva, T. V., de Barros, N. R., Costa-Orlandi, C. B., Tanaka, J. L., Moro, L. G., Brasil, G. S. P., Oliveira, K. S. M., Mendes‐Giannini, M. J. S., Fusco‐Almeida, A. M., & Herculano, R. D. (2020) · Future Microbiology · doi:10.2217/fmb-2020-0122 · Cited by 19 · see citing works

Antimicrobial Peptides Pom-1 and Pom-2 from Pomacea poeyana Are Active against Candidaauris, C. parapsilosis and C. albicans Biofilms

Raber, H. F., Sejfijaj, J., Kissmann, A., Wittgens, A., González-García, M., Alba, A., Vázquez, A. A., Morales-Vicente, F., Perez‐Erviti, J. A., Kubiczek, D. H., et al. (2021) · Pathogens · doi:10.3390/pathogens10040496 · Cited by 19 · see citing works

Epidemiology of Candidemia in Children over 7 Years in a Medical Center in Turkey

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High Incidence of Candidemia in Critically Ill COVID-19 Patients Supported by Veno-Venous Extracorporeal Membrane Oxygenation: A Retrospective Study

Alessandri, F., Ceccarelli, G., Migliara, G., Baccolini, V., Russo, A., Marzuillo, C., Ceparano, M., Giordano, G. G., Tozzi, P., Galardo, G., et al. (2023) · Journal of Fungi · doi:10.3390/jof9010119 · Cited by 18 · see citing works

The Fourier-transform infrared spectroscopy-based method as a new typing tool for Candida parapsilosis clinical isolates

Carolis, E. D., Posteraro, B., Falasca, B., Spruijtenburg, B., Meis, J. F. G. M., & Sanguinetti, M. (2023) · Microbiology Spectrum · doi:10.1128/spectrum.02388-23 · Cited by 18 · see citing works

Synthesis, structure–activity relationship and biological evaluation of indole derivatives as anti-Candida albicans agents

Wu, Y., Sun, A., Chen, F., Zhao, Y., Zhu, X., Zhang, T., Ni, G., & Wang, R. (2024) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2024.107293 · Cited by 18 · see citing works

Analysis of clinical Candida parapsilosis isolates reveals copy number variation in key fluconazole resistance genes

Bergin, S. A., Doorley, L. A., Rybak, J. M., Wolfe, K. H., Butler, G., Cuomo, C. A., & Rogers, P. D. (2024) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01619-23 · Cited by 18 · see citing works

Ethnobotanical study of Hakka traditional medicine in Ganzhou, China and their antibacterial, antifungal, and cytotoxic assessments

Hu, H., Yang, Y., Aissa, A., Tekin, V., Li, J., Panda, S. K., Huang, H., & Luyten, W. H. M. L. (2022) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-022-03712-z · Cited by 17 · see citing works

Genotypic and phenotypic characteristics of Candida parapsilosis bloodstream isolates: Health Care Associated Infections in a teaching Hospital in Italy

Caggiano, G., Fioriti, S., Morroni, G., Apollonio, F., Triggiano, F., D’Achille, G., Stefanizzi, P., Dalfino, L., Ronga, L., Mosca, A., et al. (2024) · Journal of Infection and Public Health · doi:10.1016/j.jiph.2024.04.009 · Cited by 17 · see citing works

The Transcriptional Aftermath in Two Independently Formed Hybrids of the Opportunistic Pathogen Candida orthopsilosis

Hovhannisyan, H., Saus, E., Księżopolska, E., & Gabaldón, T. (2020) · mSphere · doi:10.1128/msphere.00282-20 · Cited by 16 · see citing works

Threats from the Candida parapsilosis complex: the surge of multidrug resistance and a hotbed for new emerging pathogens

Gabaldón, T. (2024) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00029-23 · Cited by 15 · see citing works

Evaluation of MALDI-TOF MS for Identification of Species in the Candida parapsilosis Complex from Candidiasis Cases

Samantaray, S., & Singh, R. (2022) · The Journal of Applied Laboratory Medicine · doi:10.1093/jalm/jfac005 · Cited by 15 · see citing works

Antimicrobial Resistance and Biofilms Underlying Catheter-Related Bloodstream Coinfection by Enterobacter cloacae Complex and Candida parapsilosis

Štefánek, M., Wenner, S., Borges, V., Pinto, M., Gomes, J. P., Rodrigues, J., de Faria, I. C. J., Pessanha, M. A., Martins, F., Sabino, R., et al. (2022) · Antibiotics · doi:10.3390/antibiotics11091245 · Cited by 15 · see citing works

In vitro activity of sanitizers against mono- and polymicrobial biofilms of C. parapsilosis and S. aureus

Castro, V. D. P., Thomaz, D. Y., Vieira, K. D. L., Lopes, L. G., Rossi, F., Negro, G. M. B. D., Benard, G., & Pires, R. H. (2023) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00534-23 · Cited by 16 · see citing works

The Emerging Pathogen Candida metapsilosis: Biological Aspects, Virulence Factors, Diagnosis, and Treatment

Gómez-Gaviria, M., García-Carnero, L. C., Baruch-Martínez, D. A., & Mora-Montes, H. M. (2024) · Infection and Drug Resistance · doi:10.2147/idr.s448213 · Cited by 20 · see citing works

Syngonanthus nitens (Bong.) Ruhland Derivatives Loaded into a Lipid Nanoemulsion for Enhanced Antifungal Activity Against Candida parapsilosis

de Lima, L. C., Ramos, M. A. D. S., de Toledo, L. G., Rodero, C. F., Hilário, F., dos Santos, L. C., Chorilli, M., & Bauab, T. M. (2020) · Current Pharmaceutical Design · doi:10.2174/1381612826666200317131041 · Cited by 15 · see citing works

Antifungal activity of 2-chloro-N-phenylacetamide: a new molecule with fungicidal and antibiofilm activity against fluconazole-resistant Candida spp.

Neto, H. D., Silva, S. L., Cordeiro, L. V., Silva, D. F., Oliveira, R., Filho, P. F. D. A., Filho, A. A. D. O., Guerra, F. Q. S., & Lima, E. D. O. (2022) · Brazilian Journal of Biology · doi:10.1590/1519-6984.255080 · Cited by 14 · see citing works

The transcription factor Ndt80 is a repressor of Candida parapsilosis virulence attributes

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Signaling through Syk or CARD9 Mediates Species-Specific Anti-CandidaProtection in Bone Marrow Chimeric Mice

Zajta, E., Csonka, K., Tóth, A., Tiszlavicz, L., Németh, T., Orosz, A., Novák, Á., Csikós, M., Vágvölgyi, C., Mócsai, A., et al. (2021) · mBio · doi:10.1128/mbio.01608-21 · Cited by 13 · see citing works

Precise genome editing underlines the distinct contributions of mutations in ERG11 , ERG3 , MRR1 , and TAC1 genes to antifungal resistance in Candida parapsilosis

Hartuis, S., Ourliac‐Garnier, I., Robert, E., Albassier, M., Duchesne, L., Beaufils, C., Kuhn, J., Pape, P. L., & Morio, F. (2024) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00022-24 · Cited by 13 · see citing works

Epidemiology And Antifungal Susceptibility Patterns Of Invasive Fungal Infections From 2012 To 2014 In A Teaching Hospital In Central China

Xu, H., Yu, S.-Y., Zhou, M., Ning, Y., Xiao, M., Li, X.-G., Chen, M., Kong, F., Chen, S. C.-J., Ming, L., et al. (2019) · Infection and Drug Resistance · doi:10.2147/idr.s227839 · Cited by 13 · see citing works

A Candida parapsilosis Overexpression Collection Reveals Genes Required for Pathogenesis

Pál, S. E., Tóth, R., Nosanchuk, J. D., Vágvölgyi, C., Németh, T., & Gácser, A. (2021) · Journal of Fungi · doi:10.3390/jof7020097 · Cited by 13 · see citing works

Candida parapsilosis: a review of its epidemiology, pathogenesis, clinical aspects, typing and antimicrobial susceptibility

Asbeck, E. C. V., Clemons, K. V., & Stevens, D. A. (2009) · Critical Reviews in Microbiology · doi:10.3109/10408410903213393 · Cited by 213 · see citing works

Genetic Manipulation as a Tool to Unravel Candida parapsilosis Species Complex Virulence and Drug Resistance: State of the Art

Zoppo, M., Poma, N. V., Luca, M. D., Bottai, D., & Tavanti, A. (2021) · Journal of Fungi · doi:10.3390/jof7060459 · Cited by 14 · see citing works

Dissection of genotype-phenotype relationships in Candida parapsilosis uncovers drivers of clinically-relevant traitsPreprint

Schikora-Tamarit, M. À., López‐Peralta, E., Roldán, A., de Armentia, C., Torres-Cano, A., Alcázar‐Fuoli, L., CAPAR Study Group, Zaragoza, O., & Gabaldón, T. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.05.18.725882 · Cited by 1 · see citing works

Molecular epidemiology and antifungal susceptibility of Candida parapsilosis sensu stricto, Candida orthopsilosis, and Candida metapsilosis in Taiwan

Chen, Y., Lin, Y.-H., Chen, K.-W., Lii, J., Teng, H., & Li, S. (2010) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2010.07.004 · Cited by 56 · see citing works

Epidemiology and Antifungal Susceptibility of Candida Species

Chakraborty, M., Banu, H., & Gupta, M. K. (2021) · doi:10.13140/rg.2.2.32189.18400