HDAC6 Regulates Hsp90 Acetylation and Chaperone-Dependent Activation of Glucocorticoid Receptor

Kovacs, Jeffrey J., Murphy, Patrick J.M., Gaillard, Stéphanie, Zhao, Xuan, Wu, June-Tai, Nicchitta, Christopher V., Yoshida, Minoru, Toft, David O. +2 more·2005·Molecular Cell
DOI 10.1016/j.molcel.2005.04.021

Cited by (1,001)

Items 901–1,000 of 1,001

  1. Corticosterone induces growth hormone expression in pituitary somatotrophs during goose embryonic development
    Jianning Yu, Leyan Yan, Zhe Chen, Hui LI, Huanxi Zhu, Rong Chen, Zhendan Shi · 2018 · Journal of Reproduction and Development
  2. Antisense Oligonucleotide-Mediated Reduction of HDAC6 Does Not Reduce Tau Pathology in P301S Tau Transgenic Mice
    Antonio Valencia, Veronica L. Reinhart Bieber, Bekim Bajrami, Galina Marsh, Stefan Hamann, Ru Wei, Karen Ling, Frank Rigo, H. Moore Arnold, Olga Golonzhka et al. · 2021 · Frontiers in Neurology
  3. Role of Hsp90 in Plasmodium falciparum Malaria
    Dea Shahinas, Dylan R. Pillai · 2013 · Springer eBooks
  4. Role of Hsp90 in Plasmodium falciparum Malaria
    Dea Shahinas, Dylan R. Pillai · 2021 · Advances in experimental medicine and biology
  5. Deacetylation mechanism and potential reversal strategy of long QT syndrome on hERG K+ channel under hypoxia
    Hui Yi Xue, Yuexin Li, Zhengrong Zhao, Jiacheng Ren, Wenting Yu, Fang Wang, Xianghua Li, Jiaxin Li, Qianqian Xia, Yuxin Zhang et al. · 2022 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  6. Introducing Molecular Chaperones into the Causality and Prospective Management of Autoimmune Hepatitis
    Albert J. Czaja · 2023 · Digestive Diseases and Sciences
  7. Comparison of Protein Acetyltransferase Action of CRTAase with the Prototypes of HAT
    Prija Ponnan, Ajit Kumar, Prabhjot Singh, Prachi Gupta, Rini Joshi, Marco Gaspari, Luciano Saso, Ashok Kumar Prasad, Ramesh Chandra Rastogi, Virinder Singh Parmar et al. · 2014 · The Scientific World JOURNAL
  8. Discovery and Development of Small Molecules Targeting Epigenetic Enzymes with Computational Methods
    Fanwang Meng, Chen Wang, Wei Wan, Wenchao Lu, Wencong Lu, Cheng Luo · 2016 · Elsevier eBooks
  9. Microchip-based strategy for enrichment of acetylated proteins
    Lingjia Xu, Wenyan Wang, Zhengyong Zhang, Pengyuan Yang, Huizhi Fan, Jilie Kong · 2013 · Microchimica Acta
  10. Sulforaphane Inhibits Metastatic Events in Breast Cancer Cells through Genetic and Epigenetic Regulation
    Madhumita Roy Ruma Sarkar, Sutapa Mukherjee · 2015 · Journal of Carcinogenesis & Mutagenesis
  11. Glu-108 in Saccharomyces cerevisiae Rad51 Is Critical for DNA Damage-Induced Nuclear Function
    Tanvi Suhane, Vijayalakshmi Bindumadhavan, Nupur Fangaria, Achuthsankar Sukumaran Nair, Wahida Tabassum, Poorvaja Muley, Mrinal Kanti Bhattacharyya, Sunanda Bhattacharyya · 2019 · mSphere
  12. Histone Deacetylases ( HDACs ): Function, Mechanism, & Inhibition
    Sibaji Sarkar, Mckenna M. Longacre, Nela Tatur, Sarah Heerboth, KAROLINA LAPINSKA · 2000 · Encyclopedia of Analytical Chemistry
  13. Influenza A Virus: Cellular Entry
    Yasuyuki Miyake, Yuya Hara, Miki Umeda, Indranil Banerjee · 2023 · Sub-cellular biochemistry/Subcellular biochemistry
  14. Epigenetic remodeling via HDAC6 inhibition amplifies anti-tumoral immune responses in myeloid leukemia cells
    Julian Schliehe‐Diecks, Jia‐Wey Tu, Paweł Stachura, Katerina Schaal, Marie Kemkes, Eleni Vasileiou, Nadine Rüchel, Danielle Brandes, Melina Vogt, Thomas Lenz et al. · 2026 · Cell Death and Disease
  15. α-Catenin acetylation is essential for its stability and blocks its tumor suppressor effects in breast cancer through Yap1
    Yuxi Yang, Shujing Li, Yulin Li, Linlin Lv, Dongman Ye, Jie Kang, Tao Yu, Yaming Wang, Huijian Wu · 2023 · Cancer Gene Therapy
  16. Proteostasis is a key driver of the pathogenesis in Apicomplexa
    Pallabi Mitra, Abhijit S. Deshmukh · 2024 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  17. Computer-aided Drug Discovery of Epigenetic Modulators in Dual-target Therapy of Multifactorial Diseases
    Slavica Oljačić, Marija Popovic-Nikolic, Brankica Filipić, Žarko Gagić, Katarina M. Nikolic · 2024 · Current Topics in Medicinal Chemistry
  18. Inhibition of HDAC6 elicits anticancer effects on head and neck cancer cells through Sp1/SOD3/MKP1 signaling axis to downregulate ERK phosphorylation
    Rukhsana Kausar, Nga Thi Thanh Nguyen, Truc Phan Hoang Le, Jae Hyung Kim, Sang Yoon Lee · 2025 · Cellular Signalling
  19. Study on the mechanism of glucocorticoid receptor mitochondrial translocation and glucocorticoid-induced apoptosis in macrophages
    Xiaoqing Zhao, Xinglan Huang, Caifeng Huang, Xingrong Wang, Yuqi Yang, Ruonan Dang, Suiying Zhang, Yuqiong Deng, Peng Yan, Yiye Zhou et al. · 2024 · Immunopharmacology and Immunotoxicology
  20. Genetic deletion of histone deacetylase 6 prevents peritoneal fibrosis via suppression of heat shock protein 90 deacetylation
    Ying-Feng Shi, Jinqing Li, Qin Zhong, Hui Chen, Xiao-Yan Ma, Yan Hu, Yi-Shu Wang, Daofang Jiang, Xun Zhou, Xialin Li et al. · 2025 · Journal of Pathology
  21. Discovery of N-(2-Aminophenyl)-4-(bis(2-chloroethyl)amino)Benzamide as a Potent Histone Deacetylase Inhibitor
    Lihui Zhang, Xiaoyang Li, Yiming Chen, Minghui Wan, Qixiao Jiang, Li Zhang, C. James Chou, Weiguo Song, Lei Zhang · 2019 · Frontiers in Pharmacology
  22. Glucocorticosteroids
    Ian Michael Adcock, Kian Fan Chung · 2014 · Elsevier eBooks
  23. Innovative tumour targeting therapeutics in Cushing's disease
    Vivian von Selzam, Marily Theodoropoulou · 2022 · Best Practice & Research Clinical Endocrinology & Metabolism
  24. Glucose Metabolism and Liver
    Shigeatsu Hashimoto · 2016 · Springer eBooks
  25. Purification of Unanchored Polyubiquitin Chains from Influenza Virions
    Y. Miyake, Patrick Matthias, Yohei Yamauchi · 2018 · Methods in molecular biology
  26. Small‐Molecule Fluorescent Probes for Detecting HDAC Activity
    Shuyu Tan, Xin Li · 2022 · Chemistry - An Asian Journal
  27. Targeting Epigenetic Modifications for the Treatment and Prevention of Breast Cancer
    Bhuvaneswari Ramaswamy, Joseph A. Sparano · 2010 · Current Breast Cancer Reports
  28. Protein Acetylation as an Integral Part of Metabolism in Cancer Development and Progression
    Miroslava Čuperlović‐Culf, Adrian S. Culf · 2014
  29. Correction of Niemann-Pick type C1 disease with the histone deacetylase inhibitor valproic acid
    Kanagaraj Subramanian, Darren M. Hutt, Vijay Gupta, Shu Mao, William E. Balch · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  30. Glucocorticoid receptor activation reprograms NK cells to drive AREG-mediated immunosuppression in skin cancer
    Wei Dong Qin, Guirong Liang, Rui Zeng, Yuancheng Li, Anlan Hong, Hongsheng Wang, Suying Feng, Yan Wang, Yetao Wang · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  31. PROTACs improve selectivity for targeted proteins
    Lihua Liu, Xian Guan, Jiezhen Zhuo, Xifeng Wu, Xin Han · 2025 · Acta Materia Medica
  32. Interactome Profiling of a Lysine Deacetylase Trapping Probe Library Uncovers Crosstalk Between HDAC6 and NF‐κB Signaling
    Julian Seidel, Caroline Schönfeld, Julia Sindlinger, Jürgen Eirich, Sören Kirchgäßner, Nina Kreienkamp, Klaus Schulze‐Osthoff, Iris Finkemeier, Stephan Hailfinger, Dirk Schwarzer · 2025 · Angewandte Chemie International Edition
  33. Glucocorticoid Receptor Activation Reprograms NK Cells to Drive AREG‐Mediated Immunosuppression: A Pan‐Cancer Role for AREG
    Wei Dong Qin, Guirong Liang, Rui zeng, Yuancheng Li, Anlan Hong, Hongsheng Wang, Suying Feng, Yan Wang, Yetao Wang · 2025 · Advanced Science
  34. Glucocorticoid receptor signaling: crosstalk with inflammation
    Xiaoping Zhan, Baobao Song, Shunliang Xu, Hong Zhou · 2026 · Immunopharmacology and Immunotoxicology
  35. HDAC6 regulates BACE1 stability and NLRP3 inflammasome activation in Alzheimer's disease
    Jeongmi Lee, Yongeun Cho, Bo Youn Choi, Hark Kyun Kim, Yeongyeong Lee, Eunae Kim, Jihoon Han, Jae Hoon Sul, J.S. Kim, Seung Hyun Baek et al. · 2026 · Brain
  36. The Potential of Epigenetic Compounds in Treating Diabetes
    Steven G. Gray · 2018 · Elsevier eBooks
  37. Podocyte number and glomerulosclerosis indices are associated with the response to therapy for primary focal segmental glomerulosclerosis
    Natasha de Zoysa, Kotaro Haruhara, David J. Nikolic‐Paterson, Peter G. Kerr, Jonathan Ling, Sarah E. Gazzard, Victor G. Puelles, John F. Bertram, Luise A. Cullen‐McEwen · 2024 · Frontiers in Medicine
  38. Proteomics-Based Trapping to Study Substrates of Histone Deacetylase 6 Catalytic Domain 1
    Udana V. Ariyaratne, Valentine O. Nwanelo, Rachael Taiwo Tiamiyu, Ishadi K. M. Kodikara, Mary Kay H. Pflum · 2025 · Biochemistry
  39. PET imaging evidence of HDAC6 suppression in the amygdala across species in PTSD
    Robin E. Bonomi, Mika Naganawa, Delaney McRiley, Takuya Toyonaga, Brittany LeVasseur, Catharine H. Duman, Yiyun Henry Huang, David Matuskey, Richard E. Carson, Robert H. Pietrzak et al. · 2025 · Molecular Psychiatry
  40. BKS-112, a Selective Histone Deacetylase 6 Inhibitor, Suppresses Triple-Negative Breast Cancer Cells via AKT/mTOR Pathway
    Sreevarsha Gali, Swati Sharma, Hyunji Noh, In Su Kim, Hyung Sik Kim · 2025 · Antioxidants
  41. The Hsp90 Chaperone Machinery: An Important Hub in Protein Interaction Networks
    Jürgen Radons · 2016 · Journal of Advances in Medicine and Medical Research
  42. Emerging Concepts of Pathogenesis and Comprehensive Therapeutic Strategies for Spinocerebellar Ataxia Type 3
    Sagor Kumar Roy, Xiaolei Liu · 2021 · Neuroscience &amp Medicine
  43. Determination of Potential Anti-Alzheimer Activity of Gentiopicroside and Isoorientin Using Molecular Docking Studies
    Nida Nur DERELI-CALISKAN, Mehmet Tahir Hüsunet, Hasan Basri İla, Işık Didem Karagöz · 2021 · The Eurasia Proceedings of Science Technology Engineering and Mathematics
  44. In‐solution structure and oligomerization of human histone deacetylase 6 – an integrative approach
    Shivam Shukla, Jan Komárek, Zora Nováková, Jana Nedvědová, Kseniya Ustinova, Pavla Vaňková, Alan Kádek, Charlotte Uetrecht, Haydyn D. T. Mertens, Cyril Bařinka · 2022 · FEBS Journal
  45. Modification of cardiac disease by transgenically altered histone deacetylase 6
    Atsushi Sanbe, Yui Inomata, Naoko Matsushita, Yohei Sawa, Chizuru Hino, Hinano Yamazaki, Kei Takanohashi, Natsuko Takahashi, Rieko Higashio, Hideki Tsumura et al. · 2022 · Biochemical and Biophysical Research Communications
  46. Searching for Novel HDAC6/Hsp90 Dual Inhibitors with Anti-Prostate Cancer Activity: In Silico Screening and In Vitro Evaluation
    Luca Pinzi, Silvia Belluti, Isabella Piccinini, Carol Imbriano, Giulio Rastelli · 2024 · Pharmaceuticals
  47. ROS Modulatory Role of HDAC Inhibitors in Cancer Cells
    Janaki Ramaiah Mekala, Prasanna Srinivasan Ramalingam, Nageswara Rao Moparthi, Vijay Kumar Kutala · 2022 · Handbook of Oxidative Stress in Cancer: Therapeutic Aspects
  48. Effect of HDAC Inhibitors on Corneal Keratocyte Mechanical Phenotypes in 3-D Collagen Matrices.
    Vindhya Koppaka, Neema Lakshman, W. Matthew Petroll · 2015 · Europe PMC (PubMed Central)
  49. Hyperthermia and Pharmacological Intervention of Heat Shock Proteins in Anticancer Treatments
    Amere Subbarao Sreedhar · 2006 · Thermal Medicine(Japanese Journal of Hyperthermic Oncology)
  50. Inhibitors of the Zinc‐Dependent Histone Deacetylases
    Helle M. E. Kristensen, Andreas S. Madsen, Christian Adam Olsen · 2019 · Methods and principles in medicinal chemistry
  51. First Fluorescent Acetylspermidine Deacetylation Assay for HDAC10 Identifies Inhibitors of Neuroblastoma Cell Colony Growth That Increase Lysosome Accumulation
    Daniel Herp, Johannes Ridinger, Dina Robaa, Stephen A. Shinsky, Karin Schmidtkunz, Talha Z. Yesiloglu, Theresa Bayer, Peter A. Sehr, Nikolas Gunkel, Aubry K. Miller et al. · 2020 · ChemRxiv
  52. Optogenetically Induced Microtubule Acetylation Unveils the Molecular Dynamics of Actin-Microtubule Crosstalk in Directed Cell Migration
    Deb Roy, Abhijit, Saez Gonzalez, Cristian, Shahid, Farid, Yadav, Eesha, Inoue, Takanari · 2024
  53. HDAC6-Mediated FoxO1 Acetylation And Phosphorylation Control Periodontal Inflammatory Responses
    Hannah Lohner, Xiao Han, Junling Ren, Shuang Liang, Ruqiang Liang, Huizhi Wang · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  54. Design, synthesis and neuroprotective biological evaluation of novel HDAC6 inhibitors incorporating benzothiadiazinyl systems as cap groups
    Bo Ram Han, Xiu Quan Gu, Mengfei Wang, Huihao Wang, Niubing Sun, Xuezhi Yang, Qingwei Zhang · 2024 · Chemical Biology & Drug Design
  55. Rapid and sustained antidepressant effects of tubastatin A in a mouse model of depression
    Masahide Fukada, Yoshiharu Kawaguchi, Atsuo Nakayama · 2025 · Scientific Reports
  56. Endosome maturation during ER stress relies on the ubiquitin-binding domain of histone deacetylase 6
    Katherine M. Piscopo, Brooke Larson, Antje Christiansen, Jason M. Perry, Julie Hollien · 2025 · Molecular Biology of the Cell
  57. Dual targeting of Phosphoinositide 3-Kinase (PI3K) and histone deacetylase 6 (HDAC6) in cancer
    Sami Hamdoun, Nafees Ahemad, Sharifah Aminah Syed Mohamad · 2025 · Biochemical Pharmacology
  58. Ortho -Hydroxyanilides: Slow-Acting, Selective Histone Deacetylase 1/2 Inhibitors Suitable for Photocaging Applications
    Irina Honin, Tao Sun, Nisha Setia, Linda Schäker‐Hübner, Finn Kristian Hansen · 2025 · ACS Pharmacology & Translational Science
  59. HDAC6 Inhibition Drives Synaptic Protein Acetylation and Enhances Long-Term Memory in Mice
    S.P. Rivas, Laura Esquivel, Julia Busso, Angeles Salles, María Krawczyk, Melina Sol Alvarez, María Florencia Acutain, María Verónica Báez, Mariano Martín Boccia, Ramiro Freudenthal · 2025 · Molecular Neurobiology
  60. A new era in targeted sEH therapy: strategic evolution from inhibition to protein degradation
    Huizhi Yao, Chang Liu, Xin Zhou, Qi Qin, Wufu Zhu · 2026 · European Journal of Medicinal Chemistry
  61. Recommended Tool Compounds: Isoform- and Class-Specific Histone Deacetylase Inhibitors
    Linda Schäker‐Hübner, Finn Kristian Hansen · 2026 · ACS Pharmacology & Translational Science
  62. OptoTAT reveals microtubule acetylation as a rapid trigger for GEF-H1–mediated cell migration
    Deb Roy, Abhijit, Gonzalez, Cristian Saez, Stanislauskas, Milda, Shahid, Farid, Yadav, Eesha, Rezek, Jalil, Inoue, Takanari · 2026 · Journal of Cell Biology
  63. The impactful role of the HDACs in the regulation of gene expression and as targets for disease therapy
    Bryce A. Van Bree, Lillian J. Eichner · 2026 · Science Advances
  64. Determining Potency of Inhibitors Targeting Histone Deacetylase 6 by Quantification of Acetylated Tubulin in Cells
    Jana Mikesova, Marketa Ondrakova, Iva Jelínková, J. Ptáček, Zora Nováková, Cyril Bařinka · 2022 · Methods in molecular biology
  65. Delta-9 tetrahydrocannabinol (THC) effects on the cortisol stress response in bovine granulosa cells
    Jaustin Dufour, Reem Sabry, Jibran Younis Khokhar, Laura A. Favetta · 2022 · Toxicology in Vitro
  66. Therapeutic applications of the prostate cancer epigenome
    Joanne M. Cosgrave, Antoinette Sabrina Perry · 2023 · Elsevier eBooks
  67. Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder
    Greet Vanderlinden, C P Carron, Donatienne Van Weehaeghe, Joke De Vocht, Fouke Ombelet, Pegah Masrori, Caro De Weerdt, Rebecca E. James, Lauren Jayne Evans, Frederick A. Schroeder et al. · 2025 · Annals of Clinical and Translational Neurology
  68. ROS Modulatory Role of HDAC Inhibitors in Cancer Cells
    Mekala Janaki Ramaiah, Prasanna Srinivasan Ramalingam, Nageswara Rao Moparthi, Vijay Kumar Kutala · 2022 · Handbook of Oxidative Stress in Cancer: Therapeutic Aspects
  69. The Role of Histone Deacetylases in Neurodegenerative Diseases and Small-Molecule Inhibitors as a Potential Therapeutic Approach
    Roland W. Bürli, Elizabeth A. Thomas, Vahri Beaumont · 2010 · Topics in medicinal chemistry
  70. The Interplay between the Glucocorticoid Receptor Activity and post-Translational Modifications in the Immune and Neuroendocrine Systems
    María Antunica-Noguerol, Fernando Aprile-Garcia, Maia Ludmila Budziñski, Luciano Proto-Cassina, Ana C. Liberman, EDUARDO S. ARZT · 2014 · Advances in Neuroimmune Biology
  71. The Potential of Epigenetic Compounds in Treating Diabetes
    Steven G. Gray · 2012 · Elsevier eBooks
  72. Promotion of Anchorage-independent Growth by Cytoplasmic and Nuclear Histone Deacetylase 9
    Takayuki Yura, Hiroshi Hashizume, Eiko Suzuki, Masayoshi Imagawa, Shigehiro Osada · 2010 · Eisei kagaku
  73. Managing the Adaptive Proteostatic Landscape: Restoring Resilience in Alpha-1 Antitrypsin Deficiency
    Chao Wang, William E. Balch · 2015 · Respiratory medicine
  74. Structural Basis of Hsp90 Function
    Chrisostomos Prodromou, Laurence H. Pearl · 2013 · Royal Society of Chemistry eBooks
  75. In Vitro and In Vivo Primary Metabolic Characterization of F18, a Novel Histone Deacetylase-6 (HDAC6) Inhibitor, Using UHPLC–QqQ–MS/MS and Q-TOF–MS Methods
    Xiaobin Li, Minghai Tang, Hairong Wang, Liang Ma, Haoyu Ye, Chunyu Wang, Qiunan Yang, Li Wan, Lijuan Chen · 2016 · Chromatographia
  76. Important Factors in the Formation and Clearance of Protein Aggregation
    2013 · Journal of Developing Drugs
  77. Methodological approaches and insights on protein aggregation in biological systems
    Paulo André Dias Bastos, Fábio Trindade, Adelino Ferreira Leite-Moreira, Inês Falcão‐Pires, Rita M. Ferreira, Rui Miguel Pinheiro Vitorino · 2016 · Expert Review of Proteomics
  78. Opposing Effects of Valproic Acid Treatment Mediated by Histone Deacetylase Inhibitor Activity in Four Transgenic X. laevis Models of Retinitis Pigmentosa
    Ruanne Y.J. Vent-Schmidt, Runxia H. Wen, Zusheng Zong, Colette N. Chiu, Beatrice M. Tam, Christopher G. May, Orson L. Moritz · 2017 · Journal of Neuroscience
  79. Immunoprecipitation of HDAC6 and Interacting Proteins
    Longlong Wang, Jacint Sanchez, Daniel Heß, Patrick Matthias · 2022 · Methods in molecular biology
  80. Epigenetic Approaches
    Eva Sahakian, Karrune V. Woan, Alejandro Villagra, Eduardo M. Sotomayor · 2013 · Elsevier eBooks
  81. Recap of Distinct Molecular Signalling Mechanisms Modulated by Histone Deacetylases for Cancer Genesis and Progression
    Shabir Ahmad Ganai · 2020 · Springer eBooks
  82. Histone Deacetylase Inhibitors
    Paul W. Finn · 2009 · Wiley eBooks
  83. Epigenetic Targets in Drug Discovery: Cell‐Based Assays for HDAC Inhibitor Hit Validation
    Mira Jung, Kwon‐Jeong Yong, Alfredo Velena, Sung Lee · 2009 · Methods and principles in medicinal chemistry
  84. Molecular cloning and characterization of novel heat shock protein 90 gene from a wild Vitis pseduoreticulata native to China
    Yan Fang Xu, Yuejin Wang · 2009 · Biologia
  85. An investigation of the role of phosphorylation at Ser211 of the glucocorticoid receptor in ligand-specific transcriptional regulation
    Elisabeth Stubsrud · 2005 · SUNScholar (Stellenbosch University)
  86. Dihydropyrazole-Carbohydazide Derivatives with Dual Activity as Antioxidant and Anti-Proliferative Drugs on Breast Cancer Targeting the Hdac6
    Irving Balbuena-Rebolledo, Astrid M. Rivera-Antonio, Yudibeth Sixto‐López, José Correa‐Basurto, Martha Cecilia Rosales‐Hernández, Jessica Elena Mendieta‐Wejebe, Francisco J. Martı́nez-Martı́nez, Ivonne María Olivares-Corichi, José Ruben Garcia Sanchez, Juan Alberto Guevara‐Salazar et al. · 2022 · SSRN Electronic Journal
  87. Machine learning approaches to quantitively predict selectivity of compounds against hDAC1 and hDAC6 isoforms
    Berna Doğan · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  88. Class Ⅱb Histone Deacetylase Participates in Postoperative Cognitive Dysfunction in Elderly Mice via HSP90/GR Signaling Pathway
    Yu Liu, Xinlin Wang, Jiao Wang, Qiqi Jin, Weicha Cai, Chi Pan, John Nivar, Yuan‐Xiang Tao, Hong Cao, Jun Li · 2023 · Research Square
  89. HEAT SHOCK PROTEINS AS NOVEL CANCER THERAPEUTICS: TARGETING THE HALLMARKS OF CANCER
    Chao Li · 2011 · ProQuest Demo Repository
  90. Selective Disposal of Insoluble Protein Aggregates
    Pierfausto Seneci · 2015 · Elsevier eBooks
  91. Design, synthesis, and biological evaluation of quinazolin-4-one-based selective HDAC6 inhibitors targeting serine 531, histidine 614 residues, and the L1 and L2 loop
    Sunil Gupta, Yong Jin Oh, Mi Kyung Kim, Eunyoung Ha, Young Ho Seo · 2025 · European Journal of Medicinal Chemistry
  92. Novel Nitrogen Heterocycle–Hydroxamic Acid Conjugates Demonstrating Potent Anti-Acute Lymphoblastic Leukemia Activity: Induction of Endogenous Apoptosis and G0/G1 Arrest via Regulation of Histone H3 Acetylation and AKT Phosphorylation in Jurkat Cells
    Lingjie Wu, Zhao Li, Liping Wang, Yi Lu, Gaojie Lou, Bin Zhang, Ning Wang · 2025 · Cells
  93. Quinazolinone and Phthalazinone Inhibitors of the HDAC6/Ubiquitin Protein–Protein Interaction
    Sydney Gordon, Jordi C. J. Hintzen, Sebastian Dilones, Brockton Keen, Callie E. W. Crawford, George M. Burslem · 2026 · ChemBioChem
  94. HDAC6 regulates the protein stability and tumor suppressor function of HIPK2 independently of its deacetylase activity
    Boh Rah Joo, Impyo Lee, Ki Soon Shin, Shin Jung Kang · 2026 · Biochemical and Biophysical Research Communications
  95. SIRT1 mediates brain metabolic and developmental consequences of methionine synthase deficiency in inborn errors of cobalamin metabolism
    Karim Matmat, Ziad Hassan, Grégory Pourié, Yaser Atlasi, Snehaa V. Seal, Manon Jeandel, Carole Arnold, Sachin Luharia, Rémy Umoret, Ramia Safar et al. · 2026 · Cell Reports Medicine
  96. Polyphenolic compounds remodeling acetylation modifications: Unveiling potential therapeutic strategies for hematologic malignancies
    Yuhang Du, Q. LIU, Xiaoyu Yao, Minpu Zhang, Yan Yao, Changgang Sun · 2026 · Journal of Pharmaceutical Analysis
  97. Regulation of organic anion transporting polypeptide 1B1 transport function by lysine deacetylase 6
    Vikram Aditya, Vishakha Tambe, Pascaline Niyonshuti, Ruhul Kayesh, Erik J. Soderblom, Xiaohong Mary Zhang, Chao Xu, Wei Yue · 2026 · Molecular Pharmacology
  98. From design to clinic: Medicinal chemistry and pharmacology of approved epigenetic drugs
    André Berndt Penteado, Haifa Hassanie, Gustavo Henrique Marques Sousa, Thabata Corazza Navarro Vinha, Artur Caminero Gomes Soares, Raisa Ludmila Calil, Thiago dos Santos, Raul Marques Novais, Flávio da Silva Emery, A. Ganesan et al. · 2026 · European Journal of Medicinal Chemistry
  99. Therapeutic potential of histone deacetylase inhibitors for breast cancer
    Srividya Viswanathan, Sarah Carothers, Bhuvaneswari Ramaswamy · 2011 · Clinical Investigation
  100. Controversies Surrounding the Potential Use of Histone Deacetylase Inhibitors for the Treatment of Asthma
    Simon G. Royce, Katherine Ververis, Tom C. Karagiannis · 2012 · ISRN Pulmonology