Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2.

Cited by (261)

Items 101–200 of 261

  1. The Mdm network and its regulation of p53 activities: a rheostat of cancer risk
    Eischen, Christine M., Lozano, Guillermina · 2014 · Human Mutation
  2. MDM4 (MDMX) localizes at the mitochondria and facilitates the p53‐mediated intrinsic‐apoptotic pathway
    Francesca Mancini, Giusy Di Conza, Marsha Pellegrino, Cinzia Rinaldo, Andrea Prodosmo, Simona Giglio, Igea D’Agnano, Fulvio Florenzano, Lara Felicioni, Fiamma Buttitta et al. · 2009 · The EMBO Journal
  3. Increased Radioresistance and Accelerated B Cell Lymphomas in Mice with Mdmx Mutations that Prevent Modifications by DNA-Damage-Activated Kinases
    Wang, Yunyuan V., Leblanc, Mathias, Wade, Mark, Jochemsen, Aart G., Wahl, Geoffrey M. · 2009 · Cancer Cell
  4. Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 4 Targets MDM2 To Deregulate the p53 Tumor Suppressor Pathway
    Lee, Hye-Ra, Toth, Zsolt, Shin, Young C., Lee, Jong-Soo, Chang, Heesoon, Gu, Wei, Oh, Tae-Kwang, Kim, Myung Hee, Jung, Jae U. · 2009 · Journal of Virology
  5. USP7 is essential for maintaining Rad18 stability and DNA damage tolerance.
    Zlatanou, A, Sabbioneda, S, Miller, E S, Greenwalt, A, Aggathanggelou, A, Maurice, M M, Lehmann, A R, Stankovic, T, Reverdy, C, Colland, F et al. · 2016 · Oncogene
  6. Functional analysis of deubiquitylating enzymes in tumorigenesis and development
    Ji Cheng, Jianping Guo, Brian J. North, Bin Wang, Chun‐Ping Cui, Hongchang Li, Kaixiong Tao, Lingqiang Zhang, Wenyi Wei · 2019 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  7. A role for USP7 in DNA replication.
    Jagannathan, Madhav, Nguyen, Tin, Gallo, David, Luthra, Niharika, Brown, Grant W., Saridakis, Vivian, Frappier, Lori · 2014 · Molecular and Cellular Biology
  8. DNA Structure and Integrity Checkpoints during the Cell Cycle and Their Role in Drug Targeting and Sensitivity of Tumor Cells to Anticancer Treatment
    Andrzej Składanowski, Przemyslaw M. Bozko, Michał Sabisz · 2009 · Chemical Reviews
  9. Affinity Purification Strategy to Capture Human Endogenous Proteasome Complexes Diversity and to Identify Proteasome-interacting Proteins
    Marie‐Pierre Bousquet, Émilie Baudelet, Frédéric Guèrin, Mariette Matondo, Sandrine Uttenweiler‐Joseph, Odile Burlet‐Schiltz, Bernard Monsarrat · 2009 · Molecular & Cellular Proteomics
  10. Crystal Structure of USP7 Ubiquitin-like Domains with an ICP0 Peptide Reveals a Novel Mechanism Used by Viral and Cellular Proteins to Target USP7
    Roland Pfoh, Ira Kay Lacdao, Anna A. Georges, Adam Capar, Hong Xing Zheng, Lori Frappier, V. Saridakis · 2015 · PLoS Pathogens
  11. Inhibition of p53 DNA Binding Function by the MDM2 Protein Acidic Domain
    Brittany L. Cross, Lihong Chen, Qian Cheng, Baozong Li, Zhi-Min Yuan, Jiandong Chen · 2011 · Journal of Biological Chemistry
  12. c-Abl Phosphorylates Hdmx and Regulates Its Interaction with p53
    Zuckerman, Valentina, Lenos, Kristiaan, Popowicz, Grzegorz M., Silberman, Isabelle, Grossman, Tamar, Marine, Jean-Christophe, Holak, Tad A., Jochemsen, Aart G., Haupt, Ygal · 2009 · Journal of Biological Chemistry
  13. Regulation of the Mdm2-p53 signaling axis in the DNA damage response and tumorigenesis
    Michael I. Carr, Stephen N. Jones · 2016 · Translational Cancer Research
  14. Phosphorylation and Degradation of MdmX Is Inhibited by Wip1 Phosphatase in the DNA Damage Response
    Zhang, Xinna, Lin, Lin, Guo, Huarong, Yang, Jianhua, Jones, Stephen N., Jochemsen, Aart, Lu, Xiongbin · 2009 · Cancer Research
  15. Updates on p53: modulation of p53 degradation as a therapeutic approach
    A Dey, Chandra Shekhar Verma, David Philip Lane · 2008 · British Journal of Cancer
  16. Early adipogenesis is regulated through USP7-mediated deubiquitination of the histone acetyltransferase TIP60
    Yuan Gao, Arjen Koppen, Maryam Rakhshandehroo, Ismayil Taşdelen, Stan F.J. van de Graaf, Jorg van Loosdregt, Olivier van Beekum, Nicole Hamers, Dik van Leenen, Celia R. Berkers et al. · 2013 · Nature Communications
  17. Gambogic acid triggers DNA damage signaling that induces p53/p21Waf1/CIP1 activation through the ATR-Chk1 pathway
    Jingjing Rong, Rong Hu, Xiuming Song, Jun Ha, Na Lu, Qi Qi, Lei Tao, Qidong You, Qinglong Guo · 2010 · Cancer Letters
  18. The Ubiquitin-Specific Protease USP7 Modulates the Replication of Kaposi's Sarcoma-Associated Herpesvirus Latent Episomal DNA
    Wiebke Jäger, Susann Santag, Magdalena Weidner-Glunde, Eva Gellermann, Semra Kati, Marcel Pietrek, Abel Viejo‐Borbolla, Thomas Friedrich Schulz · 2012 · Journal of Virology
  19. A role of HAUSP in tumor suppression in a human colon carcinoma xenograft model.
    Becker, Kerstin, Marchenko, Natalia, Palacios, Gustavo, Moll, Ute M. · 2008 · Cell Cycle
  20. p53 Regulates the Extent of Fibroblast Proliferation and Fibrosis in Left Ventricle Pressure Overload
    Xiaoyi Liu, Ryan M. Burke, Janet K. Lighthouse, Cameron D. Baker, Ronald A Dirkx, Brian Kang, Yashoswini Chakraborty, Deanne M. Mickelsen, Jennifer J. Twardowski, Stephano S. Mello et al. · 2023 · Circulation Research
  21. Interplay between MDM2, MDMX, Pirh2 and COP1: the negative regulators of p53
    Lan Wang, Guifen He, Pingzhao Zhang, Xiang Wang, Mei Hua Jiang, Long Yu · 2010 · Molecular Biology Reports
  22. Chemotherapy induces NEDP1-mediated destabilization of MDM2
    Ian R. Watson, Bryan K. Li, O Roche, A Blanch, Michael Ohh, Meredith S. Irwin · 2009 · Oncogene
  23. What happens at the lesion does not stay at the lesion: Transcription-coupled nucleotide excision repair and the effects of DNA damage on transcription in cis and trans
    Marit E. Geijer, Jurgen A. F. Marteijn · 2018 · DNA repair
  24. The herpesvirus associated ubiquitin specific protease, USP7, is a negative regulator of PML proteins and PML nuclear bodies.
    Sarkari, Feroz, Wang, Xueqi, Nguyen, Tin, Frappier, Lori · 2011 · PLoS ONE
  25. Gene expression control by protein deubiquitinases
    Lori Frappier, C. Peter Verrijzer · 2011 · Current Opinion in Genetics & Development
  26. Targeting the Ubiquitin-Mediated Proteasome Degradation of p53 for Cancer Therapy
    Tiffany DeVine, Mu‐Shui Dai · 2013 · Current Pharmaceutical Design
  27. Generation and Validation of Intracellular Ubiquitin Variant Inhibitors for USP7 and USP10
    Wei Zhang, Maria Augusta Sartori, Taras Makhnevych, Kelly Federowicz, Xiaohui Dong, Li Liu, Satra Nim, Aiping Dong, Jingsong Yang, Yanjun Li et al. · 2017 · Journal of Molecular Biology
  28. Ticking time bombs: connections between circadian clocks and cancer
    Katja A Lamia · 2017 · F1000Research
  29. OTUD5 Regulates p53 Stability by Deubiquitinating p53
    Judong Luo, Zhonghua Lu, Xujing Lu, Ling Chen, Jianping Cao, Shuyu Zhang, Ling Yang, Xifa Zhou · 2013 · PLoS ONE
  30. HDMX-L Is Expressed from a Functional p53-responsive Promoter in the First Intron of the HDMX Gene and Participates in an Autoregulatory Feedback Loop to Control p53 Activity
    Phillips, Anna, Teunisse, Amina, Lam, Suzanne, Lodder, Kirsten, Darley, Matthew, Emaduddin, Muhammad, Wolf, Anja, Richter, Julia, de Lange, Job, Verlaan-de Vries, Matty et al. · 2010 · Journal of Biological Chemistry
  31. Further insight into substrate recognition by USP7: structural and biochemical analysis of the HdmX and Hdm2 interactions with USP7.
    Sarkari, Feroz, La Delfa, Anthony, Arrowsmith, Cheryl H., Frappier, Lori, Sheng, Yi, Saridakis, Vivian · 2010 · Journal of Molecular Biology
  32. Deubiquitinating enzyme regulation of the p53 pathway: A lesson from Otub1
    Xiao‐Xin Sun · 2014 · World Journal of Biological Chemistry
  33. Ubiquitin-specific protease 7 expression is a prognostic factor in epithelial ovarian cancer and correlates with lymph node metastasis
    Nina Yu, Ming Ma · 2016 · OncoTargets and Therapy
  34. Hyperubiquitylation of wild-type p53 contributes to cytoplasmic sequestration in neuroblastoma
    K Becker, N D Marchenko, Madelon M. Maurice, Ute Martha Moll · 2007 · Cell Death and Differentiation
  35. USP7 is a novel deubiquitinase sustaining PLK1 protein stability and regulating chromosome alignment in mitosis.
    Peng, Yuchong, Liu, Youhong, Gao, Yingxue, Yuan, Bowen, Qi, Xuli, Fu, Yuxin, Zhu, Qianling, Cao, Tuoyu, Zhang, Songwei, Yin, Linglong et al. · 2019 · Journal of Experimental & Clinical Cancer Research
  36. Targeting the ubiquitin–proteasome system to activate wild-type p53 for cancer therapy
    Nerea Allende-Vega, Mark K. Saville · 2009 · Seminars in Cancer Biology
  37. Monoubiquitination Is Critical for Ovarian Tumor Domain-containing Ubiquitin Aldehyde Binding Protein 1 (Otub1) to Suppress UbcH5 Enzyme and Stabilize p53 Protein
    Yuhuang Li, Xiao‐Xin Sun, Johannes Elferich, Ujwal P. Shinde, Larry L. David, Mu‐Shui Dai · 2014 · Journal of Biological Chemistry
  38. The role of deubiquitinating enzymes in cancer drug resistance
    Parthasaradhireddy Tanguturi, Kye-Seong Kim, Suresh Ramakrishna · 2020 · Cancer Chemotherapy and Pharmacology
  39. UVSSA and USP7, a new couple in transcription-coupled DNA repair
    Schwertman, Petra, Vermeulen, Wim, Marteijn, Jurgen A · 2013 · Chromosoma
  40. Identification of Kaposi Sarcoma Herpesvirus (KSHV) vIRF1 Protein as a Novel Interaction Partner of Human Deubiquitinase USP7
    Sara Chavoshi, Olga Egorova, Ira Kay Lacdao, Sahar Farhadi, Yi Sheng, V. Saridakis · 2016 · Journal of Biological Chemistry
  41. Structurally-defined deubiquitinase inhibitors provide opportunities to investigate disease mechanisms
    Ingrid E. Wertz, Jeremy M. Murray · 2019 · Drug Discovery Today Technologies
  42. Casein Kinase 1α Regulates an MDMX Intramolecular Interaction To Stimulate p53 Binding
    Shaofang Wu, Lihong Chen, Andreas Becker, E. Schönbrunn, Jiandong Chen · 2012 · Molecular and Cellular Biology
  43. The E3 Ubiquitin Ligase ARIH1 Protects against Genotoxic Stress by Initiating a 4EHP-Mediated mRNA Translation Arrest
    Louise von Stechow, Dimitris Typas, Jordi Carreras Puigvert, Laurens Oort, Ramakrishnaiah Siddappa, Alex Pines, Harry Vrieling, Bob van de Water, Leon H.F. Mullenders, Erik H.J. Danen · 2015 · Molecular and Cellular Biology
  44. Recent advances in the development of ubiquitin-specific-processing protease 7 (USP7) inhibitors
    Peng Li, Hong-Min Liu · 2020 · European Journal of Medicinal Chemistry
  45. Proteome Changes Induced by Knock-Down of the Deubiquitylating Enzyme HAUSP/USP7
    Benedikt Mathias Kessler, Elisabetta Fortunati, Monique H. M. Melis, Cornelieke E. G. M. Pals, Hans C. Clevers, Madelon M. Maurice · 2007 · Journal of Proteome Research
  46. SRC-3 coactivator regulates cell resistance to cytotoxic stress via TRAF4-mediated p53 destabilization
    Ping Yi, Weiya Xia, Ray‐Chang Wu, David Michael Lonard, Mien‐Chie Hung, Bert W. O’Malley · 2013 · Genes & Development
  47. Active-site directed probes to report enzymatic action in the ubiquitin proteasome system
    Huib Ovaa · 2007 · Nature reviews. Cancer
  48. Chemical Approaches to Intervening in Ubiquitin Specific Protease 7 (USP7) Function for Oncology and Immune Oncology Therapies
    Jian Wu, Suresh Kumar, Feng Wang, Hui Wang, Lijia Chen, Patrick Arsenault, Michael R. Mattern, Joseph Weinstock · 2017 · Journal of Medicinal Chemistry
  49. The intricate interplay between HIFs, ROS, and the ubiquitin system in the tumor hypoxic microenvironment
    Yijie Wang, Xiong Liu, Weixiao Huang, Junjie Liang, Yan Chen · 2022 · Pharmacology & Therapeutics
  50. HAUSP-nucleolin interaction is regulated by p53-Mdm2 complex in response to DNA damage response
    Key‐Hwan Lim, Jang-Joon Park, Bon‐Hee Gu, Jin-Ock Kim, Sang Gyu Park, Kwang‐Hyun Baek · 2015 · Scientific Reports
  51. Cooperative Roles of c-Abl and Cdk5 in Regulation of p53 in Response to Oxidative Stress
    Jong‐Hee Lee, Min-Woo Jeong, Wanil Kim, Yoon Ha Choi, Kyong‐Tai Kim · 2008 · Journal of Biological Chemistry
  52. The role of deubiquitinases in breast cancer
    Zhenna Xiao, Peijing Zhang, Li Ma · 2016 · Cancer and Metastasis Reviews
  53. MDM2 promotes genome instability by ubiquitinating the transcription factor HBP1
    Zhengyi Cao, Junhui Xue, Yuning Cheng, Jiyin Wang, Yujuan Liu, Hui Li, Wei Jiang, Gang Li, Yaoting Gui, Xiaowei Zhang · 2019 · Oncogene
  54. USP7/HAUSP stimulates repair of oxidative DNA lesions
    Svetlana V. Khoronenkova, Irina I. Dianova, Jason Luke Parsons, Grigory L. Dianov · 2010 · Nucleic Acids Research
  55. MDM4 (MDMX) and its Transcript Variants
    F. Mancini, Giusy Di Conza, Fabiola Moretti · 2009 · Current Genomics
  56. A Survey of the Interactome of Kaposi's Sarcoma-Associated Herpesvirus ORF45 Revealed Its Binding to Viral ORF33 and Cellular USP7, Resulting in Stabilization of ORF33 That Is Required for Production of Progeny Viruses
    Joseph Gillen, Wenwei Li, Qiming Liang, Denis R. Avey, Jianjun Wu, Fayi Wu, Jinjong Myoung, Fanxiu Zhu · 2015 · Journal of Virology
  57. Stabilization of Ultraviolet (UV)-stimulated Scaffold Protein A by Interaction with Ubiquitin-specific Peptidase 7 Is Essential for Transcription-coupled Nucleotide Excision Repair
    Mitsuru Higa, Xue Zhang, Kiyoji Tanaka, Masafumi Saijo · 2016 · Journal of Biological Chemistry
  58. Otub1 stabilizes MDMX and promotes its proapoptotic function at the mitochondria
    Yingxiao Chen, Yue-Gang Wang, Yuhuang Li, Xiao‐Xin Sun, Mu‐Shui Dai · 2016 · Oncotarget
  59. MDM2 and MDMX in Cancer and Development
    Jean‐Christophe Marine · 2011 · Current topics in developmental biology/Current Topics in Developmental Biology
  60. Switching on p53: an essential role for protein phosphorylation?
    Jayne Loughery, David W. Meek · 2013 · Biodiscovery
  61. Tumor suppressor OTUD3 induces growth inhibition and apoptosis by directly deubiquitinating and stabilizing p53 in invasive breast carcinoma cells
    Qian Pu, Yanrong Lv, Ke Dong, Wenwen Geng, Haidong Gao · 2020 · BMC Cancer
  62. Functions of MDMX in the Modulation of the p53‐Response
    Kristiaan Lenos, Aart G. Jochemsen · 2011 · BioMed Research International
  63. Multiple neurotoxic stresses converge on MDMX proteolysis to cause neuronal apoptosis
    Samir Benosman, Isabelle Groß, Nicole Clarke, Aart G. Jochemsen, Koji Okamoto, Jean‐Philippe Loeffler, Christian Gaiddon · 2007 · Cell Death and Differentiation
  64. Mouse bites dogma: how mouse models are changing our views of how P53 is regulated in vivo
    Geoffrey M. Wahl · 2006 · Cell Death and Differentiation
  65. The ATM regulated DNA damage response pathway as a chemo- and radiosensitisation target
    John Patrick Alao · 2009 · Expert Opinion on Drug Discovery
  66. USP7 regulates the stability and function of HLTF through deubiquitination.
    Qing, Peng, Han, Lu, Bin, Liu, Yan, Lu, Ping, Wen Xue · 2011 · Journal of Cellular Biochemistry
  67. Dissecting the role of ubiquitylation in the DNA damage response checkpoint in G2
    Florian C. Bassermann, Michele Pagano · 2009 · Cell Death and Differentiation
  68. Redox regulation of DUBs and its therapeutic implications in cancer
    Apoorvi Tyagi, Saba Haq, Suresh Ramakrishna · 2021 · Redox Biology
  69. The roles of MDM2 and MDMX phosphorylation in stress signaling to p53
    Chen, J. · 2012 · Genes & Cancer
  70. Cytoplasmic tethering is involved in synergistic inhibition of p53 by Mdmx and Mdm2
    Ohtsubo, Chihiro, Shiokawa, Daisuke, Kodama, Masami, Gaiddon, Christian, Nakagama, Hitoshi, Jochemsen, Aart G., Taya, Yoichi, Okamoto, Koji · 2009 · Cancer Science
  71. USP7 manipulation by viral proteins
    Anna Bojagora, V. Saridakis · 2020 · Virus Research
  72. Quantitative Assessment of the p53-Mdm2 Feedback Loop Using Protein Lysate Microarrays
    Sundhar Ramalingam, Peter Honkanen, Lynn Young, Tsutomu Shimura, John Austin, Patricia Schriver Steeg, Satoshi Nishizuka · 2007 · Cancer Research
  73. Stochastic Modeling and Simulation of the p53-MDM2/MDMX Loop
    Xiaodong Cai, Zhi-Min Yuan · 2009 · Journal of Computational Biology
  74. Recent advances in the development of deubiquitinases inhibitors as antitumor agents
    Lili Zheng, Liting Wang, Ye-Wei Pang, Li‐Ping Sun, Lei Shi · 2024 · European Journal of Medicinal Chemistry
  75. HAUSP, a deubiquitinating enzyme for p53, is polyubiquitinated, polyneddylated, and dimerized
    Hye‐Jin Lee, Myung‐Sun Kim, Yu‐Kyung Kim, Yu‐Kyoung Oh, Kwang‐Hyun Baek · 2005 · FEBS Letters
  76. Tumor suppressor protein Pdcd4 interacts with Daxx and modulates the stability of Daxx and the Hipk2-dependent phosphorylation of p53 at serine 46
    Kumar, N, Wethkamp, N, Waters, L C, Carr, M D, Klempnauer, K-H · 2013 · Oncogenesis
  77. MicroRNA-205 regulates ubiquitin specific peptidase 7 protein expression in hepatocellular carcinoma cells
    Liang Wei Zhu, Rong Liu, Wei Zhang, Sheng Qian, Jianhua Wang · 2015 · Molecular Medicine Reports
  78. The Human T-Cell Leukemia Virus Type 1 Oncoprotein Tax Controls Forkhead Box O4 Activity through Degradation by the Proteasome
    Alexandra Oteiza, Nadir Mechti · 2011 · Journal of Virology
  79. Nucleotide Excision Repair: Finely Tuned Molecular Orchestra of Early Pre‐incision Events
    Qianzheng Zhu, Altaf A. Wani · 2016 · Photochemistry and Photobiology
  80. The Shelterin Component TPP1 Is a Binding Partner and Substrate for the Deubiquitinating Enzyme USP7
    Ivo Zemp, Joachim Lingner · 2014 · Journal of Biological Chemistry
  81. Regulation of Vaccinia Virus E3 Protein by Small Ubiquitin-Like Modifier Proteins
    José González, Michela Campagna, María Ángel García, Laura Marcos-Villar, Dolores González de Llano, Pedro Pablo Ferrer Gallego, Fernando Lopitz‐Otsoa, Susana Guerra, Manuel S. Rodríguez, Mariano Estéban et al. · 2011 · Journal of Virology
  82. Low-Toxicity Sulfonium-Based Probes for Cysteine-Specific Profiling in Live Cells
    Rui Ying Wang, Dongyan Yang, Tian Tian, Yuhao An, Chuan Wan, Qi Chang, Mingchan Liang, Zhanfeng Hou, Ying Wang, Liang N. Zhang et al. · 2022 · Analytical Chemistry
  83. Regulation of cellular responses by deubiquitinating enzymes: an update
    James, F. Burrows · 2011 · Frontiers in bioscience
  84. Protein phosphatase 1 inhibits p53 signaling by dephosphorylating and stabilizing Mdmx
    Zengxin Lu, Guohui Wan, Huarong Guo, Xinna Zhang, Xiongbin Lu · 2012 · Cellular Signalling
  85. The SUMO‐specific protease SENP1 deSUMOylates p53 and regulates its activity
    Krishna M. Chauhan, Yingxiao Chen, Yiyi Chen, Andrew T. Liu, Xiao‐Xin Sun, Mu‐Shui Dai · 2020 · Journal of Cellular Biochemistry
  86. MDM2 promotes the proteasomal degradation of p73 through the interaction with Itch in HeLa cells
    Natsumi Kubo, Rintaro Okoshi, Kumiko Nakashima, Osamu Shimozato, Akira Nakagawara, Toshinori Ozaki · 2010 · Biochemical and Biophysical Research Communications
  87. Coupling Conjugation and Deconjugation Activities to Achieve Cellular Ubiquitin Dynamics
    Casey P. Nielsen, Jason A. MacGurn · 2020 · Trends in Biochemical Sciences
  88. p53 Family: Therapeutic Targets in Neuroblastoma
    Jennifer K. Wolter, Paola Angelini, Meredith S. Irwin · 2010 · Future Oncology
  89. USP7 inactivation suppresses APC-mutant intestinal hyperproliferation and tumor development
    Laura Novellasdemunt, Anna Kucharska, Anna Baulies, Colin Hutton, Georgios Vlachogiannis, Dimitra Repana, Andrew Rowan, Alejandro Suárez‐Bonnet, Francesca D. Ciccarelli, Nicola Valeri et al. · 2023 · Stem Cell Reports
  90. USP7-mediated deubiquitination differentially regulates CSB but not UVSSA upon UV radiation-induced DNA damage
    Qianzheng Zhu, Nan Ding, Shengcai Wei, Ping Li, Gulzar Wani, Jinshan He, Altaf A. Wani · 2019 · Cell Cycle
  91. Targeting HAUSP in both p53 wildtype and p53-mutant tumors
    Omid Tavana, Hongbin Sun, Wei Jun Gu · 2018 · Cell Cycle
  92. Timely upstream events regulating nucleotide excision repair by ubiquitin-proteasome system: ubiquitin guides the way
    Anil K. Chauhan, Yingming Sun, Qianzheng Zhu, Altaf A. Wani · 2021 · DNA repair
  93. Selective protein degradation in cell signalling
    Han Liu, Sylvie Urbé, Michael J. Clague · 2012 · Seminars in Cell and Developmental Biology
  94. Ataxin-7 and Non-stop coordinate SCAR protein levels, subcellular localization, and actin cytoskeleton organization
    Veronica J. Cloud, Ada Thapa, Pedro Morales‐Sosa, Tayla M Miller, Sara Miller, Daniel Holsapple, Paige M Gerhart, Elaheh Momtahan, Jarrid L. Jack, Edgardo Leiva et al. · 2019 · eLife
  95. Structural Basis of the Interaction Between Ubiquitin Specific Protease 7 and Enhancer of Zeste Homolog 2
    Varvara Gagarina, Anna Bojagora, Ira Kay Lacdao, Niharika Luthra, Roland Pfoh, Sadaf Mohseni, Danica Chaharlangi, Nadine Tan, V. Saridakis · 2019 · Journal of Molecular Biology
  96. Regulation of MDM4 (MDMX) function by p76MDM2: a new facet in the control of p53 activity
    Simona Giglio, F Mancini, Marsha Pellegrino, Giusy Di Conza, Efisio Puxeddu, Ada Sacchi, Alfredo Pontecorvi, Fabiola Moretti · 2010 · Oncogene
  97. The multiple roles of deubiquitinases in liver cancer.
    Xinyou Lv, Ting Duan, Jin Li · 2020 · PubMed Central
  98. METTL3 facilitates the progression of hepatocellular carcinoma by modulating the m6A level of USP7.
    Yaqin Li, Xianyi Cheng, Yihua Chen, Tao You Zhou, Dezhi Li, Wei Zheng · 2021 · PubMed Central
  99. The key vulnerabilities and therapeutic opportunities in the USP7-p53/MDM2 axis in cancer
    Gouranga Saha, Mrinal K. Ghosh · 2025 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  100. Identification of a novel higher molecular weight isoform of USP7/HAUSP that interacts with the Herpes simplex virus type-1 immediate early protein ICP0
    Robin Antrobus, Chris Boutell · 2008 · Virus Research