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COP1 and ELF3 Control Circadian Function and Photoperiodic Flowering by Regulating GI Stability
Open accessAbstract
SUMMARY Seasonal changes in day length are perceived by plant photoreceptors and transmitted to the circadian clock to modulate developmental responses, such as flowering time. Blue light-sensing cryptochromes, the E3 ubiquitin-ligase COP1, and clock-associated proteins ELF3 and GI, regulate this process, although the regulatory link between them is unclear. Here, we present data showing that COP1 acts with ELF3 to mediate day length signaling from CRY2 to GI within the photoperiod flowering pathway. We found that COP1 and ELF3 interact in vivo and show that ELF3 allows COP1 to interact with GI in vivo, leading to GI degradation in planta. Accordingly, mutation of COP1 or ELF3 disturbs the pattern of GI cyclic accumulation. We propose a model in which ELF3 acts as a substrate adaptor, enabling COP1 to modulate light input signal to the circadian clock through targeted destabilization of GI.
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Citations
Cited by
Phytochrome Signaling Mechanisms
Li, J., Li, G., Wang, H., & Wang Deng, X. (2011) · The Arabidopsis Book · doi:10.1199/tab.0148 · Cited by 561
The clock gene circuit in Arabidopsis includes a repressilator with additional feedback loops
Pokhilko, A., Fernández, A. P., Edwards, K. D., Southern, M. M., Halliday, K. J., & Millar, A. J. (2012) · Molecular Systems Biology · doi:10.1038/msb.2012.6 · Cited by 409
Hormonal regulation of temperature‐induced growth in Arabidopsis
Stavang, J. A., Gallego‐Bartolomé, J., Gómez, M. D., Yoshida, S., Asami, T., Olsen, J. E., García‐Martínez, J. L., Alabadí, D., & Blázquez, M. A. (2009) · The Plant Journal · doi:10.1111/j.1365-313x.2009.03983.x · Cited by 331
Higgins, J. A., Bailey, P. C., & Laurie, D. A. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010065 · Cited by 280
Suetsugu, N., & Wada, M. (2013) · Plant and Cell Physiology · doi:10.1093/pcp/pcs165 · Cited by 122
Metadata
- Authors
- Yu, J.-W., Rubio, V., Lee, N.-Y., Bai, S., Lee, S.-Y., Kim, S.-S., Liu, L., Zhang, Y., Irigoyen, M. L., Sullivan, J. A., Zhang, Y., Lee, I., Xie, Q., Paek, N.-C., & Deng, X. W.
- Venue
- Molecular Cell
- Publisher
- Elsevier BV
- Published
- 2008-12
- Volume
- 32
- Issue
- 5
- Pages
- 617-630
- ISSN
- 1097-2765 (ISSN-L)
- OpenAlex
- W2046971770
- Cited by
- 425
- References
- 0
- FWCI
- 18.13
- Type
- journal article
- Language
- en
- Open access
- bronze
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- The paper
- Yu, J.-W., Rubio, V., Lee, N.-Y., Bai, S., Lee, S.-Y., Kim, S.-S., Liu, L., Zhang, Y., Irigoyen, M. L., Sullivan, J. A., Zhang, Y., Lee, I., Xie, Q., Paek, N.-C., & Deng, X. W. (2008). COP1 and ELF3 Control Circadian Function and Photoperiodic Flowering by Regulating GI Stability. Molecular Cell. https://doi.org/10.1016/j.molcel.2008.09.026
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