The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.
Regulation of Autophagy by Cytosolic Acetyl-Coenzyme A
Open accessAbstract
Acetyl-coenzyme A (AcCoA) is a major integrator of the nutritional status at the crossroads of fat, sugar, and protein catabolism. Here we show that nutrient starvation causes rapid depletion of AcCoA. AcCoA depletion entailed the commensurate reduction in the overall acetylation of cytoplasmic proteins, as well as the induction of autophagy, a homeostatic process of self-digestion. Multiple distinct manipulations designed to increase or reduce cytosolic AcCoA led to the suppression or induction of autophagy, respectively, both in cultured human cells and in mice. Moreover, maintenance of high AcCoA levels inhibited maladaptive autophagy in a model of cardiac pressure overload. Depletion of AcCoA reduced the activity of the acetyltransferase EP300, and EP300 was required for the suppression of autophagy by high AcCoA levels. Altogether, our results indicate that cytosolic AcCoA functions as a central metabolic regulator of autophagy, thus delineating AcCoA-centered pharmacological strategies that allow for the therapeutic manipulation of autophagy.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“In fact, acetyl-CoA controls longevity and autophagy in a panel of model systems (Eisenberg et al., 2014; Mariño et al., 2014): This energy metabolite integrates various nutrition pathways and is the only known donor in acetylation reactions.”
From The Search for Antiaging Interventions: From Elixirs to Fasting Regimens (2014) · cites this paper as Mariño et al., 2014
Citations
Cites
López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013) · Cell · doi:10.1016/j.cell.2013.05.039 · Cited by 14,982
Self-citationAutophagy in the Pathogenesis of Disease
Levine, B., & Kroemer, G. (2008) · Cell · doi:10.1016/j.cell.2007.12.018 · Cited by 7,069
Autophagy: Renovation of Cells and Tissues
Mizushima, N., & Komatsu, M. (2011) · Cell · doi:10.1016/j.cell.2011.10.026 · Cited by 6,615
Autophagy and the Integrated Stress Response
Kroemer, G., Mariño, G., & Levine, B. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.09.023 · Cited by 3,506
Self-citationTFEB Links Autophagy to Lysosomal Biogenesis
Settembre, C., Di Malta, C., Polito, V. A., Arencibia, M. G., Vetrini, F., Erdin, S., Erdin, S. U., Huynh, T., Medina, D., Colella, P., et al. (2011) · Science · doi:10.1126/science.1204592 · Cited by 3,365
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
Cantó, C., Gerhart-Hines, Z., Feige, J. N., Lagouge, M., Noriega, L., Milne, J. C., Elliott, P. J., Puigserver, P., & Auwerx, J. (2009) · Nature · doi:10.1038/nature07813 · Cited by 3,300
ATP-citrate lyase links cellular metabolism to histone acetylation
Wellen, K. E., Hatzivassiliou, G., Sachdeva, U. M., Bui, T. V., Cross, J. R., & Thompson, C. B. (2009) · Science · doi:10.1126/science.1164097 · Cited by 2,298
Mizushima, N., Yamamoto, A., Matsui, M., Yoshimori, T., & Ohsumi, Y. (2004) · Molecular Biology of the Cell · doi:10.1091/mbc.e03-09-0704 · Cited by 2,105
Induction of autophagy by spermidine promotes longevity
Eisenberg, T., Knauer, H., Schauer, A., Büttner, S., Ruckenstuhl, C., Carmona-Gutierrez, D., Ring, J., Schroeder, S., Magnes, C., Antonacci, L., et al. (2009) · Nature Cell Biology · doi:10.1038/ncb1975 · Cited by 1,680
Network organization of the human autophagy system
Behrends, C., Sowa, M. E., Gygi, S. P., & Harper, J. W. (2010) · Nature · doi:10.1038/nature09204 · Cited by 1,554
Flagged first, then by citations
Cited by
Sorted by citations
Items 401–498 of 498
Moving towards a novel therapeutic strategy for hyperammonemia that targets glutamine metabolism
Fukui, K., Takahashi, T., Matsunari, H., Uchikura, A., Watanabe, M., Nagashima, H., Ishihara, N., Kakuma, T., Watanabe, Y., Yamashita, Y., et al. (2022) · Journal of Inherited Metabolic Disease · doi:10.1002/jimd.12540 · Cited by 4
Raimundo, N., Fernández-Mosquera, L., & Yambire, K. F. (2016) · Springer eBooks · doi:10.1007/978-1-4939-3612-0_9 · Cited by 4
Epi-Regulation of Cell Death in Cancer
Beato, A., Torre, L. D., Capone, V., Carannante, D., Favale, G., Verrilli, G., Altucci, L., & Carafa, V. (2023) · Biochemistry · doi:10.5772/intechopen.108919 · Cited by 4
Zhao, J., Jiang, Y., Sun, X., Liu, X.-S., Liu, F., Song, M., & Zhang, L. (2020) · Bioscience Reports · doi:10.1042/bsr20193385 · Cited by 4
Jamalpoor, A., van Gelder, C. A. G. H., Yengej, F. A. Y., Zaal, E. A., Berlingerio, S. P., Veys, K. R. P., Casellas, C. P., Voskuil, K., Essa, K., Ammerlaan, C. M. E., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.02.10.941799 · Cited by 4
Autophagic signaling promotes systems-wide remodeling in skeletal muscle upon oncometabolic stressPreprint
Karlstaedt, A., Vitrac, H., Salazar, R., Gould, B. D., Soedkamp, D., Spivia, W. R., Raedschelders, K., Dinh, A. Q., Guzman, A. G., Tan, L., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.10.13.338202 · Cited by 4
Zhang, J., Wu, D., Lei, R., Zhang, F., Wu, W., Wu, Y. Z., Zhang, Z., Han, D., Chen, L., Yu, Y., et al. (2025) · Journal of Advanced Research · doi:10.1016/j.jare.2025.09.008 · Cited by 3
Liu, Y., Yan, Z., Fu, Z., Wu, X., Wang, F., & Yuan, Y. (2025) · Cell Death Discovery · doi:10.1038/s41420-025-02809-x · Cited by 3
The Roles of Caloric Restriction Mimetics in Central Nervous System Demyelination and Remyelination
Kaffe, D., Kaplanis, S. I., & Karagogeos, D. (2023) · Current Issues in Molecular Biology · doi:10.3390/cimb45120596 · Cited by 4
Phutela, K., Bal, A., Singh, N., & Sharma, S. (2025) · Nanoscale Advances · doi:10.1039/d5na00094g · Cited by 3
Naumova, N., Koliada, A. K., Kuzub, N., & Vaiserman, A. M. (2023) · Elsevier eBooks · doi:10.1016/b978-0-12-823679-6.00012-6 · Cited by 3
Calorie Restriction Mimetics From Functional Foods
Sun, W. Y., & Wang, Y. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-805376-8.00022-8 · Cited by 3
Autophagie et système cardiovasculaire
Kheloufi, M., Rautou, P., & Boulanger, C. M. (2017) · médecine/sciences · doi:10.1051/medsci/20173303015 · Cited by 4
Gregg, C. J. (2021) · Frontiers in Ecology and Evolution · doi:10.3389/fevo.2021.693781 · Cited by 4
Guan, S. P., Kumar, S. N., Fann, D. Y., & Kennedy, B. K. (2022) · Alcohol · doi:10.1016/j.alcohol.2022.07.009 · Cited by 3
Methionine coordinates a hierarchically organized anabolic program enabling proliferationPreprint
Walvekar, A. S., Srinivasan, R., Gupta, R., & Laxman, S. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/249367 · Cited by 3
Gohir, W., Kennedy, K. M., Wallace, J. G., Saoi, M., Bellissimo, C. J., Britz‐McKibbin, P., Petrik, J., Surette, M. G., & Sloboda, D. M. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/436816 · Cited by 3
Polyamines and autophagy as a dynamic regulatory network in skeletal muscle regeneration and aging
Attili, L., Rossi, M. N., Santo, R. D., Duranti, G., Ceci, R., & Cervelli, M. (2026) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2026.112188 · Cited by 3
Delineating the role of autophagy in driving the resistance to cancer chemotherapy
Shantanu, P. A., Syamprasad, N. P., Rajdev, B., Gawali, B., Kumar, A., Rahman, T., & Naidu, V. G. M. (2021) · Annals of Oncology Research and Therapy · doi:10.4103/aort.aort_26_21 · Cited by 2
A big picture of the mitochondria-mediated signals: From mitochondria to organism
Acar, N. V., & Özgül, R. K. (2023) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2023.08.032 · Cited by 2
Yu, F., Hu, G., Xu, J., Song, S., Zhao, Z., & Lu, L. (2023) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2023.105077 · Cited by 2
Lü, G., Yang, L., Zhang, Q., Zhang, S., Xiong, Y., Li, T., Zhang, Y. L., Liu, M., Zhang, Y., Wu, J., et al. (2025) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2025.110465 · Cited by 2
Indraccolo, S. (2015) · Molecular & Cellular Oncology · doi:10.1080/23723556.2015.1008307 · Cited by 2
Regulation of Macroautophagy by Nutrients and Metabolites
Lorin, S., Pattingre, S., Meijer, A. J., & Codogno, P. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802167-5.00014-1 · Cited by 2
Role of Autophagy in Cancer Metabolism
Cheong, H. (2016) · InTech eBooks · doi:10.5772/64025 · Cited by 2
Heterogeneous cellular effects of α-ketoglutarate esters
Galluzzi, L. (2019) · Aging · doi:10.18632/aging.102028 · Cited by 2
Pathogenic hyperactivation of mTORC1 by cytoplasmic EP300 in Hutchinson-Gilford progeria syndrome
Ferret, L., Kroemer, G., & Djavaheri‐Mergny, M. (2024) · Cell Stress · doi:10.15698/cst2024.04.295 · Cited by 2
Liu, X., Huang, S., Xu, P., Xu, H.-W., Wang, D., & Wang, S.-J. (2025) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2025.119933 · Cited by 2
The Role of Autophagy during Nontuberculous Mycobacterial Infection
Kim, Y. J., Sapkota, A., Lee, B., Park, E., & Jo, E. (2025) · Journal of Bacteriology and Virology · doi:10.4167/jbv.2025.55.3.205 · Cited by 1
Kravtsova, O., Tan, Y., Levchenko, V., Kovalenko, E., Tiwari, R., Zietara, A. P., Bohovyk, R., Dissanayake, L. V., Van, T., Sharp, T. E., et al. (2025) · iScience · doi:10.1016/j.isci.2025.114505 · Cited by 1
Fueling Disease: ACSS2 in Obesity‐Associated Metabolic Disorders and Cancer Progression
Chen, L., Wang, Y., & Yang, J. (2026) · Obesity Reviews · doi:10.1111/obr.70096 · Cited by 1
Karimi, K., Roberts, S. C., Carter, N. S., Hofer, S. J., & Karimi, R. (2026) · Amino Acids · doi:10.1007/s00726-026-03512-6 · Cited by 1
The Temporal Architecture of Human Cells: Organelle Clocks and Distributed Circadian Time
Bautista, J., & López‐Cortés, A. (2026) · BioEssays · doi:10.1002/bies.70157 · Cited by 2
Metabolic danger signals: TCA cycle metabolites regulate immunity and disease
Ryan, T. A. J., & Zanoni, I. (2026) · Cell chemical biology · doi:10.1016/j.chembiol.2026.07.004 · Cited by 1
Cardiac Autophagy and Its Regulation by Reversible Protein Acetylation
Xie, M., & Hill, J. A. (2016) · Cardiac and vascular biology · doi:10.1007/978-3-319-41457-7_10 · Cited by 1
Spermidine and its role in inducing autophagy in cardiac muscle to prevent cardiac dysfunction
Hassan, I., & Mirbahai, L. (2020) · Reinvention an International Journal of Undergraduate Research · doi:10.31273/reinvention.v13i1.519 · Cited by 1
Linking Cellular Metabolism to Epigenetics in Melanoma
Guo, W., & Li, C. (2021) · International Journal of Dermatology and Venereology · doi:10.1097/jd9.0000000000000191 · Cited by 1
Molecular dynamics of autophagy in cancer metabolism
Pandey, R., Kanwar, J. R., Kumar, D., Gupta, V. K., & Kumar, A. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-99879-6.00005-5 · Cited by 1
“Diet and Exercise Will Help You Live Longer”: The Meme that Turns on Housekeeping Genes
Escobar, K. A., Visconti, L. M., Wallace, A., & VanDusseldorp, T. A. (2019) · Advances in Geriatric Medicine and Research · doi:10.20900/agmr20200002 · Cited by 2
De novo lipogenesis fuels adipocyte autophagosome membrane dynamicsPreprint
Rowland, L. A., Guilherme, A., Henriques, F. D. S., DiMarzio, C., Wetoska, N., Kelly, M., Reddig, K. R., Hendricks, G. M., Pan, M., Han, X., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.05.25.493413 · Cited by 1
Mechanisms and Dynamics of Protein Acetylation in
Baeza, M., Smallegan, M. J., & Denu, J. M. (2016)
Rerouting 'coenzyme A' biosynthesis
Srinivasan, B. (2015) · University of Groningen research database (University of Groningen / Centre for Information Technology)
A metabolic master regulator of autophagy and longevity
Schroeder, S., Pendl, T., Zimmermann, A., Eisenberg, T., Carmona‐Gutiérrez, D., Ruckenstuhl, C., Mariño, G., Pietrocola, F., Harger, A., Magnes, C., et al. (2014)
Metabolomics in Assessment of Nutritional Status
Hanhineva, K. (2017) · Wiley eBooks · doi:10.1002/9781119105916.ch5
Role of human arylamine n-acetyltransferase 1 in tumorigenesis and cancer biology.
Stepp, M. W. (2017) · ThinkIR: The University of Louisville's Institutional Repository (University of Louisville) · doi:10.18297/etd/2862
Verdauung und Darmerkrankungen
Fegerl, S. P., Sartor, H., & Witasek, A. (2019) · Springer eBooks · doi:10.1007/978-3-662-58111-7_6
A systems chemoproteomic analysis of acyl-CoA/protein interaction networksPreprint
Levy, M. J., Montgomery, D. C., Sardiu, M. E., Bergholtz, S. E., Nance, K. D., Montano, J., Thorpe, A. L., Fox, S. D., Lin, Q., Andresson, T., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/665281
Diagnostik und Therapie nach F. X. Mayr
Fegerl, S. P., & Witasek, A. (2019) · Springer eBooks · doi:10.1007/978-3-662-48879-9_22
Kochetkova, E. Y., Blinova, G. I., Boytsov, A., Поспелов, В. А., & Pospelova, T. V. (2020) · Cell and Tissue Biology · doi:10.1134/s1990519x20060061
Diet’s impact dictated by synonymous mitochondrial SNP interacting with nucleotypePreprint
Dobson, A. J., Voigt, S., Kumpitsch, L., Langer, L., Voigt, E., Ibrahim, R., Dowling, D. K., & Reinhardt, K. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.03.07.434274
Metabolic aspects of canonical versus noncanonical autophagy
Castoldi, F., & Pietrocola, F. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-820538-9.00001-6
Escobar, K. A., & VanDusseldorp, T. A. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-817990-1.00050-0
Liebl, M. P., Meister, S. C., Frey, L., Hendrich, K., Klemmer, A., Pohl, C., & Lakics, V. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.07.12.452036
Dysregulated myogenesis and autophagy in genetically induced pulmonary emphysemaPreprint
Balnis, J., Drake, L. A., Singer, D. V., Vincent, C. E., Korponay, T. C., D'Armiento, J. M., Lee, C. G., Elias, J. A., Singer, H. A., & Jaitovich, A. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.07.08.450201
Heinz, D. (2021) · Publication Server of Goethe University Frankfurt am Main (Goethe University Frankfurt) · doi:10.21248/gups.65210
Advances in the Regulation of Autophagy
夏, 丹. (2019) · Advances in Clinical Medicine · doi:10.12677/acm.2019.93027
Faculty Opinions recommendation of Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A.
Bogan, J. S. (2019) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.733953691.793554906
Faculty Opinions recommendation of Mechanisms and dynamics of protein acetylation in mitochondria.
Ji, L. L. (2019) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.726108102.793564356
Bhowmick, S., Beckmann, M., Shen, J., & Mur, L. A. J. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.05.23.493049
Nishtuk, Y. V., Stasyk, O. V., & Stasyk, O. G. (2022) · Studia Biologica · doi:10.30970/sbi.1603.691
Mechanism for Suppressing Visceral Fat Accumulation of Resveratrol
Yanai, T. (2018) · JOURNAL OF THE BREWING SOCIETY OF JAPAN · doi:10.6013/jbrewsocjapan.113.2
Wang, Y.-X., Ke, X.-G., Wang, C., Peng, K., Wu, H., & Yang, Y. (2023) · Pharmacognosy Magazine · doi:10.1177/09731296231197299
Coorey, N., Tollestrup, I., Bircham, P. W., Sheridan, J. P., Evans, G. B., Schramm, V. L., Atkinson, P. H., & Munkacsi, A. B. (2025) · Disease Models & Mechanisms · doi:10.1242/dmm.052173
Li, L.-L., Zhang, Y., Fu, Y., Jiang, H., Zhang, X., Yin, T., Li, X., Ren, Q., & Lu, Y. (2025) · SSRN Electronic Journal · doi:10.2139/ssrn.5371522
Becher, M. L., Zhai, F., Gilbert, M. L., Mota, D. I., Griffiths, L. A., Pierre, M., Athreya, A. R., Boyd, F. S., Cameron, A. M., Cameron, M. R., et al. (2024) · Developmental Biology · doi:10.1016/j.ydbio.2025.07.020
Eat, Heal, Repeat: How zebrafish master regeneration
Pérez-Montes, C., Lavado-Fernández, E., Martínez-Rojo, I., Santos-Ledo, A., & García-Macia, M. (2025) · International review of cytology · doi:10.1016/bs.ircmb.2025.10.008
Skalidis, I., Tüting, C., & Kastritis, P. L. (2020) · Figshare · doi:10.6084/m9.figshare.12864899
Wang, J., Xu, C., Sun, Q., Xu, J., Chai, Y., Berg, G., Cernava, T., Ma, Z., & Chen, Y. (2021) · Figshare · doi:10.6084/m9.figshare.14741192
Wang, J., Xu, C., Sun, Q., Xu, J., Chai, Y., Berg, G., Cernava, T., Ma, Z., & Chen, Y. (2021) · Figshare · doi:10.6084/m9.figshare.14741189
Mariño, G., Tamargo‐Gómez, I., García, R., Martínez-García, G. G., Suárez, M. F., Cimadevilla, O. C. F., Caravia, X. M., Pérez, R. F., Rey, V., Calvo, M., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.09.29.678527
Sharma, B., Negi, R., Jain, S., Chaudhury, S., & Singh, P. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-30060-8.00011-x · Cited by 1
Disruption of zinc homeostasis reduces histone acetylation levels in normal and tumor cells
Xu, S., Hu, Y., Tang, C., & Xu, W. (2026) · Scientific Reports · doi:10.1038/s41598-026-35270-6
Garg, M. (2026) · World Journal of Clinical Oncology · doi:10.5306/wjco.v17.i3.115094
Pietrocola, F. (2015) · theses.fr (ABES) · doi:10.70675/42d6808dzc206z4e0fzb806z29f806b2f781 · Cited by 1
Obésité et méta-inflammation : rôle du système lysosomal-autophagique et des protéines associées
Soussi, H. (2016) · theses.fr (ABES) · doi:10.70675/77e61e80zde3cz4030z95f1z194698d236d8
Vanin-1 et la réponse mésenchymateuse à un stress inflammatoire ou tumoral
Giessner, C. (2015) · theses.fr (ABES) · doi:10.70675/ad91f126zab69z4befzb47bz6ebe23e41f19
Role of Chloride in Modulating Autophagy : Cystic Fibrosis as a Disease Model
Zhang, S. (2018) · theses.fr (ABES) · doi:10.70675/aade8b2ez4194z4addza263z0496a36afc12
A proteomic approach for understanding the metabolic adaptations in non-small cell lung cancer
Martín-Bernabé, A. (2018) · theses.fr (ABES) · doi:10.70675/426e7b40z057az4326z8cfez7da3a5c12c7e
Aspirin recapitulates features of caloric restriction
Castoldi, F. (2018) · theses.fr (ABES) · doi:10.70675/02f5de46z9573z4f0dz9b29z3fa5274e9088
Modulation de l'autophagie neuronale par la sérine protéase tPA en conditions ischémiques
Thiebaut, A. M. (2019) · theses.fr (ABES) · doi:10.70675/6586c0abz9e4cz455fz95ffzc52ec76397f8
Functional characterisation of Drosophila M1BP
Barthez, M. (2019) · theses.fr (ABES) · doi:10.70675/38635cdczfedaz4361zb0a3z7b6850e707ed
Biochemical characterization of mTORC1 regulation by glutamine metabolism
Bodineau, C. (2020) · theses.fr (ABES) · doi:10.70675/9d5aaabdz81bdz4118zb3edze237bdd8dee0
Autophagy mediates the hormonal regulation of neuronal homeostasis and brain aging
Rivagorda, M. (2021) · theses.fr (ABES) · doi:10.70675/e4cd7313zfed5z4ebezb547z9b4557da55e6
Metabolic Roles of Acyl Coenzyme A-Binding Protein (ACBP)/Diazepam Binding Inhibitor (DBI)
Joseph, A. (2021) · theses.fr (ABES) · doi:10.70675/b045685ezd444z4b46zb0f9z0e726ceac466
Ramos‐Morales, E. (2021) · theses.fr (ABES) · doi:10.70675/c6b28473zf6b6z4024z99bfz05629f0484d7
Le métabolisme de l'inflammation dans les maladies microcristallines
Pham, C. N. (2024) · theses.fr (ABES) · doi:10.70675/f0753276z83c0z49a8zaacfz19b5d72e5627
Inflammaging: Immune–Metabolic Crosstalk Between the Prostate–Testis and Musculoskeletal System
Bossio, S., Russa, D. L., Rago, V., Dio, M. D., Aversa, A., & Perri, A. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27083612 · Cited by 1
Oliveira, Â. Z., Almeida, L. M., Oliveira, J. M. A., & Pinho, B. R. (2026) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-026-05573-3
Research progress on spermidine for the amelioration of metabolic diseases
Shuang-Bin, W. A. N. G., Rui-Ze, A. I., Zhang, Y.-J., HUANG, Q.-C., Xiao-Xia, F. A. N., & Le-Le, J. I. (2026) · Shengming kexue · doi:10.3724/cbls.2026049
Ou, H., Tsai, K., Yang, H.-L., Huang, Y., Cheng, H.-C., Chou, W.-C., & Hsieh, P. (2026) · ACS Omega · doi:10.1021/acsomega.5c12039
Bagge, E. K., Kubota‐Sakashita, M., Fujimori-Tonou, N., Kasahara, T., & Kato, T. (2026) · Neuroscience Research · doi:10.1016/j.neures.2026.105089
Wang, K., Zhang, G., 李长虹, & Zhao, Y. (2026) · Environmental Pollution · doi:10.1016/j.envpol.2026.129303
Borrelli, S., Masola, V., Prosdocimi, T., Corbett, R., Trepiccione, F., Liberato, L. D., Bonomini, M., Manna, G. L., Magnoni, G., Nardelli, L., et al. (2026) · Peritoneal Dialysis International · doi:10.1177/08968608261493817
Bartoszewicz, M., & Niemczyk, M. (2026) · Aging · doi:10.18632/aging.206426
Revisiting Inherited Metabolic Diseases ( IMDs ) Through the Lens of Selective Autophagy
Maddaluno, M., Cinque, L., Cetrangolo, V., & Leonibus, C. D. (2026) · Journal of Inherited Metabolic Disease · doi:10.1002/jimd.70259
Nutrients and Their Role in Autophagy Regulation
Wilson, N., Koçak, G., Sarkar, S., Ruiz, Y. R., & Korolchuk, V. I. (2026) · Biochemistry · doi:10.1021/acs.biochem.6c00482
Metadata
- Authors
- Mariño, G., Pietrocola, F., Eisenberg, T., Kong, Y., Malik, S. A., Andryushkova, A., Schroeder, S., Pendl, T., Harger, A., Niso-Santano, M., Zamzami, N., Scoazec, M., Durand, S., Enot, D. P., Fernández, Á. F., Martins, I., Kepp, O., Senovilla, L., Bauvy, C., Morselli, E., Vacchelli, E., Bennetzen, M., Magnes, C., Sinner, F., Pieber, T., López-Otín, C., Maiuri, M. C., Codogno, P., Andersen, J. S., Hill, J. A., Madeo, F., & Kroemer, G.
- Affiliations
- Inserm (FR)
- University of Graz (AT)
- The University of Texas Southwestern Medical Center (US)
- Joanneum Research (AT)
- Universidad de Oviedo (ES)
- University of Southern Denmark (DK)
- Corresponding author
- Madeo, Frank
- Kroemer, Guido
- ORCID
- Mariño, Guillermo
- Pietrocola, Federico
- Eisenberg, Tobias
- Malik, Shoaib Ahmad
- Pendl, Tobias
- Fernández, Álvaro F.
- Martins, Isabelle
- Kepp, Oliver
- Senovilla, Laura
- Morselli, Eugenia
- Vacchelli, Erika
- Magnes, Christoph
- Sinner, Frank
- Pieber, Thomas
- Maiuri, Maria Chiara
- Codogno, Patrice
- Andersen, Jens S.
- Hill, Joseph A.
- Madeo, Frank
- Kroemer, Guido
- Venue
- Molecular Cell
- Publisher
- Elsevier BV
- Published
- 2014-03
- Volume
- 53
- Issue
- 5
- Pages
- 710-725
- ISSN
- 1097-2765 (ISSN-L)
- OpenAlex
- W2095000965
- Cited by
- 500
- References
- 53
- Citations by year
- 2026: 19 · 2025: 28 · 2024: 33 · 2023: 32 · 2022: 41 · 2021: 52 · 2020: 51 · 2019: 54 · 2018: 50 · 2017: 34 · 2016: 39 · 2015: 39 · 2014: 28
- FWCI
- 35.35
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Molecular Cell (publishedVersion)
- PubMed (publishedVersion)
- Institutional Repository University of Extremadura (University of Extremadura) (submittedVersion, other-oa)
- Consultation of the Doctoral Thesis Database (TESEO) (Ministerio de Educación, Cultura y Deporte) (submittedVersion, cc-by-nc-nd)
- University of Southern Denmark Research Portal (University of Southern Denmark) (submittedVersion)
- Funders
- Agence Nationale de la Recherche (ANR-11-PHUC-0002)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Autophagy in Disease and Therapy
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Physiology › Calcium signaling and nucleotide metabolism
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Metabolism, Diabetes, and Cancer
- Keywords
- acetyl-CoA, autophagy regulation, protein acetylation, nutrient deprivation, EP300, acetyltransferase, cardiac pressure overload, metabolic regulation, autophagy induction, autophagy inhibition
- MeSH terms
- Acetyl Coenzyme A, Adenosine Triphosphate, Animals, Autophagy, Cell Nucleus, Cytoplasm, Cytosol, HeLa Cells, Humans, Ketoglutaric Acids, Mice, Inbred C57BL, Microscopy, Fluorescence, Mitochondria, Gene Expression Regulation, Enzymologic, RNA, Small Interfering, HCT116 Cells, Cell Line, Tumor, Green Fluorescent Proteins, E1A-Associated p300 Protein, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review