The Cohesin Complex Prevents the End Joining of Distant DNA Double-Strand Ends

Pathways of DNA Double-Strand Break Repair during the Mammalian Cell Cycle

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A Direct Link between Sister Chromatid Cohesion and Chromosome Condensation Revealed through the Analysis of MCD1 in S. cerevisiae

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A Central Role for Cohesins in Sister Chromatid Cohesion, Formation of Axial Elements, and Recombination during Yeast Meiosis

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Homology-directed repair is a major double-strand break repair pathway in mammalian cells

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DNA Damage Response Pathway Uses Histone Modification to Assemble a Double-Strand Break-Specific Cohesin Domain

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Postreplicative Recruitment of Cohesin to Double-Strand Breaks Is Required for DNA Repair

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Positional stability of single double-strand breaks in mammalian cells

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AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching

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Is Non-Homologous End-Joining Really an Inherently Error-Prone Process?

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Cohesin-mediated interactions organize chromosomal domain architecture

Sofueva, S., Yaffe, E., Chan, W., Georgopoulou, D., Vietri Rudan, M., Mira‐Bontenbal, H., Pollard, S. M., Schroth, G. P., Tanay, A., & Hadjur, S. (2013) · The EMBO Journal · doi:10.1038/emboj.2013.237 · Cited by 394 · see citing works

Role of mammalian Mre11 in classical and alternative nonhomologous end joining

Xie, A., Kwok, A., & Scully, R. (2009) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1640 · Cited by 351 · see citing works

Impact of the KU80 Pathway on NHEJ-Induced Genome Rearrangements in Mammalian Cells

Guirouilh‐Barbat, J., Huck, S., Bertrand, P., Pirzio, L. M., Desmaze, C., Sabatier, L., & López, B. S. (2004) · Molecular Cell · doi:10.1016/j.molcel.2004.05.008 · Cited by 335 · see citing works

Characterization of homologous recombination induced by replication inhibition in mammalian cells

Saintigny, Y., Delacôte, F., Varès, G., Petitot, F., Lambert, S., Averbeck, D., & López, B. S. (2001) · The EMBO Journal · doi:10.1093/emboj/20.14.3861 · Cited by 334 · see citing works

DNA Ligase III Promotes Alternative Nonhomologous End-Joining during Chromosomal Translocation Formation

Simsek, D., Brunet, E., Wong, S., Katyal, S., Gao, Y., McKinnon, P. J., Lou, J. F., Zhang, L., Li, J., Rebar, E. J., et al. (2011) · PLoS Genetics · doi:10.1371/journal.pgen.1002080 · Cited by 327 · see citing works

Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells

Rass, E., Grabarz, A., Plo, I., Gautier, J., Bertrand, P., & López, B. S. (2009) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1641 · Cited by 325 · see citing works

Preventing Nonhomologous End Joining Suppresses DNA Repair Defects of Fanconi Anemia

Adamo, A., Collis, S. J., Adelman, C. A., Silva, N., Hořejšı́, Z., Ward, J. D., Martínez-Pérez, E., Boulton, S. J., & Volpe, A. L. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.06.026 · Cited by 297 · see citing works

Human SMC5/6 complex promotes sister chromatid homologous recombination by recruiting the SMC1/3 cohesin complex to double‐strand breaks

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Ku70 Corrupts DNA Repair in the Absence of the Fanconi Anemia Pathway

Pace, P., Mosedale, G., Hodskinson, M. R. G., Rosado, I. V., Sivasubramaniam, M., & Patel, K. J. (2010) · Science · doi:10.1126/science.1192277 · Cited by 239 · see citing works

The maintenance of chromosome structure: positioning and functioning of SMC complexes

Jeppsson, K. E., Kanno, T., Shirahige, K., & Sjögren, C. (2014) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3857 · Cited by 206 · see citing works

Defects in XRCC4 and KU80 differentially affect the joining of distal nonhomologous ends

Guirouilh‐Barbat, J., Rass, E., Plo, I., Bertrand, P., & López, B. S. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0708541104 · Cited by 180 · see citing works

A role for CTCF and cohesin in subtelomere chromatin organization, TERRA transcription, and telomere end protection

Deng, Z., Wang, Z., Stong, N., Plasschaert, R. N., Moczan, A., Chen, H.-S., Hu, S., Wickramasinghe, P., Davuluri, R. V., Bartolomei, M. S., et al. (2012) · The EMBO Journal · doi:10.1038/emboj.2012.266 · Cited by 174 · see citing works

The causes of replication stress and their consequences on genome stability and cell fate

Magdalou, I., López, B. S., Pasero, P., & Lambert, S. (2014) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2014.04.035 · Cited by 157 · see citing works

Activation-Induced Cytidine Deaminase-Dependent DNA Breaks in Class Switch Recombination Occur during G1 Phase of the Cell Cycle and Depend upon Mismatch Repair

Schrader, C. E., Guikema, J. E. J., Linehan, E. K., Selsing, E., & Stavnezer, J. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.179.9.6064 · Cited by 150 · see citing works

Is homologous recombination really an error-free process?

Guirouilh‐Barbat, J., Lambert, S., Bertrand, P., & López, B. S. (2014) · Frontiers in Genetics · doi:10.3389/fgene.2014.00175 · Cited by 142 · see citing works

Cohesin Protects Genes against γH2AX Induced by DNA Double-Strand Breaks

Caron, P., Aymard, F., Iacovoni, J. S., Briois, S., Canitrot, Y., Bugler, B., Massip, L., Losada, A., & Legube, G. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002460 · Cited by 135 · see citing works

Cohesin Association to Replication Sites Depends on Rad50 and Promotes Fork Restart

Tittel-Elmer, M., Lengronne, A., Davidson, M. B., Bacal, J., François, P., Hohl, M., Petrini, J. H. J., Pasero, P., & Cobb, J. A. (2012) · Molecular Cell · doi:10.1016/j.molcel.2012.07.004 · Cited by 128 · see citing works

Chromosome translocation based on illegitimate recombination in human tumors

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Cohesin promotes the repair of ionizing radiation-induced DNA double-strand breaks in replicated chromatin

Bauerschmidt, C., Arrichiello, C., Burdak‐Rothkamm, S., Woodcock, M., Hill, M. A., Stevens, D. L., & Rothkamm, K. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkp976 · Cited by 105 · see citing works

SMC1 involvement in fragile site expression

Musio, A., Montagna, C., Mariani, T., Tilenni, M., Focarelli, M. L., Brait, L., Indino, E., Benedetti, P. A., Chessa, L., Albertini, A., et al. (2005) · Human Molecular Genetics · doi:10.1093/hmg/ddi049 · Cited by 104 · see citing works

Cohesin and the nucleolus constrain the mobility of spontaneous repair foci

Dion, V., Kalck, V., Seeber, A., Schleker, T., & Gasser, S. M. (2013) · EMBO Reports · doi:10.1038/embor.2013.142 · Cited by 103 · see citing works

Importance of the cell cycle phase for the choice of the appropriate DSB repair pathway, for genome stability mintenance: the trans-S double-strand break repair model

Delacôte, F., & López, B. S. (2008) · Cell Cycle · doi:10.4161/cc.7.1.5149 · Cited by 100 · see citing works

Suppression of RAD21 gene expression decreases cell growth and enhances cytotoxicity of etoposide and bleomycin in human breast cancer cells

Atienza, J. M., Roth, R. B., Rosette, C., Smylie, K. J., Kammerer, S., Rehbock, J., Ekblom, J., & Denissenko, M. F. (2005) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-04-0241 · Cited by 96 · see citing works

Initiation of DNA double strand break repair: signaling and single-stranded resection dictate the choice between homologous recombination, non-homologous end-joining and alternative end-joining.

Grabarz, A., Barascu, A., Guirouilh‐Barbat, J., & López, B. S. (2012) · Europe PMC (PubMed Central) · Cited by 93 · see citing works

Distinct Functions of Human Cohesin-SA1 and Cohesin-SA2 in Double-Strand Break Repair

Kong, X., Ball, A. R., Pham, H. X., Zeng, W., Chen, H.-Y., Schmiesing, J. A., Kim, J.-S., Berns, M. W., & Yokomori, K. (2013) · Molecular and Cellular Biology · doi:10.1128/mcb.01503-13 · Cited by 92 · see citing works

Cohesin in development and disease

Remeseiro, S., Cuadrado, A., & Losada, A. (2013) · Development · doi:10.1242/dev.090605 · Cited by 87 · see citing works

The cohesin complex regulates immunoglobulin class switch recombination

Thomas-Claudepierre, A.-S., Schiavo, E., Heyer, V., Fournier, M. L., Page, A., Robert, I., & Reina‐San‐Martin, B. (2013) · The Journal of Experimental Medicine · doi:10.1084/jem.20130166 · Cited by 67 · see citing works

Recruitment of the cohesin loading factor NIPBL to DNA double-strand breaks depends on MDC1, RNF168 and HP1γ in human cells

Oka, Y., Suzuki, K., Yamauchi, M., Mitsutake, N., & Yamashita, S. (2011) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2011.07.021 · Cited by 44 · see citing works

A regulatory role for the cohesin loader NIPBL in nonhomologous end joining during immunoglobulin class switch recombination

Enervald, E., Du, L., Visnes, T., Björkman, A., Lindgren, E. B., Wincent, J., Borck, G., Colleaux, L., Cormier‐Daire, V., van Gent, D. C., et al. (2013) · The Journal of Experimental Medicine · doi:10.1084/jem.20130168 · Cited by 44 · see citing works

S-phase progression stimulates both the mutagenic KU-independent pathway and mutagenic processing of KU-dependent intermediates, for nonhomologous end joining

Guirouilh‐Barbat, J., Huck, S., & López, B. S. (2007) · Oncogene · doi:10.1038/sj.onc.1210807 · Cited by 37 · see citing works

SMC complexes: from DNA to chromosomes

Uhlmann, F. (2016) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2016.30 · Cited by 524 · see citing works

Single-cell atlas reveals correlates of high cognitive function, dementia, and resilience to Alzheimer’s disease pathology

Mathys, H., Peng, Z., Boix, C. A., Victor, M. B., Leary, N., Babu, S., Abdelhady, G., Jiang, X., Ng, A. P., Ghafari, K., et al. (2023) · Cell · doi:10.1016/j.cell.2023.08.039 · Cited by 495 · see citing works

The molecular basis and disease relevance of non-homologous DNA end joining

Zhao, B., Rothenberg, E., Ramsden, D. A., & Lieber, M. R. (2020) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-020-00297-8 · Cited by 389 · see citing works

Loop extrusion as a mechanism for formation of DNA damage repair foci

Arnould, C., Rocher, V., Finoux, A.-L., Clouaire, T., Li, K., Zhou, F., Caron, P., Mangeot, P. E., Ricci, E. P., Mourad, R., et al. (2021) · Nature · doi:10.1038/s41586-021-03193-z · Cited by 341 · see citing works

Sliding sleeves of XRCC4–XLF bridge DNA and connect fragments of broken DNA

Brouwer, I., Sitters, G., Candelli, A., Heerema, S. J., Heller, I., de Melo, A. J., Zhang, H., Normanno, D., Modesti, M., Peterman, E. J. G., et al. (2016) · Nature · doi:10.1038/nature18643 · Cited by 166 · see citing works

Studying DNA Double-Strand Break Repair: An Ever-Growing Toolbox

Vítor, A. C., Huertas, P., Legube, G., & de Almeida, S. F. (2020) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2020.00024 · Cited by 148 · see citing works

Genome control by SMC complexes

Hoencamp, C., & Rowland, B. D. (2023) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-023-00609-8 · Cited by 138 · see citing works

Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration

Dileep, V., Boix, C. A., Mathys, H., Marco, A., Welch, G. M., Meharena, H. S., Loon, A., Jeloka, R., Peng, Z., Bennett, D. A., et al. (2023) · Cell · doi:10.1016/j.cell.2023.08.038 · Cited by 130 · see citing works

Repression of Transcription at DNA Breaks Requires Cohesin throughout Interphase and Prevents Genome Instability

Meisenberg, C., Pinder, S. I., Hopkins, S. R., Wooller, S. K., Benstead-Hume, G., Pearl, F. M. G., Jeggo, P. A., & Downs, J. A. (2018) · Molecular Cell · doi:10.1016/j.molcel.2018.11.001 · Cited by 126 · see citing works

Cohesin regulates homology search during recombinational DNA repair

Piazza, A., Bordelet, H., Dumont, A., Thierry, A., Savocco, J., Girard, F., & Koszul, R. (2021) · Nature Cell Biology · doi:10.1038/s41556-021-00783-x · Cited by 115 · see citing works

A cohesin/HUSH- and LINC-dependent pathway controls ribosomal DNA double-strand break repairPreprint

Marnef, A., Finoux, A.-L., Arnould, C., Guillou, E., Daburon, V., Rocher, V., Mangeat, T., Mangeot, P. E., Ricci, E. P., & Legube, G. (2019) · Genes & Development · doi:10.1101/gad.324012.119 · Cited by 112 · see citing works

Repair of a Site-Specific DNA Cleavage: Old-School Lessons for Cas9-Mediated Gene Editing

Gallagher, D. N., & Haber, J. E. (2017) · ACS Chemical Biology · doi:10.1021/acschembio.7b00760 · Cited by 88 · see citing works

DNA damage induces nuclear envelope rupture through ATR-mediated phosphorylation of lamin A/C

Kovacs, M. T., Vallette, M., Wiertsema, P., Dingli, F., Loew, D., Nader, G. P. F., Piel, M., & Ceccaldi, R. (2023) · Molecular Cell · doi:10.1016/j.molcel.2023.09.023 · Cited by 87 · see citing works

Organizing DNA repair in the nucleus: DSBs hit the road

Marnef, A., & Legube, G. (2017) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2016.12.003 · Cited by 79 · see citing works

The Emerging Role of Cohesin in the DNA Damage Response

Litwin, I., Pilarczyk, E., & Wysocki, R. (2018) · Genes · doi:10.3390/genes9120581 · Cited by 74 · see citing works

PDS5 proteins are required for proper cohesin dynamics and participate in replication fork protection

Morales, C., Ruiz‐Torres, M., Rodríguez‐Acebes, S., Lafarga, V., Rodríguez-Corsino, M., Megı́as, D., Cisneros, D. A., Peters, J., Méndez, J., & Losada, A. (2019) · Journal of Biological Chemistry · doi:10.1074/jbc.ra119.011099 · Cited by 78 · see citing works

Cohesin Mutations in CancerPreprint

Koninck, M. D., & Losada, A. (2016) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a026476 · Cited by 76 · see citing works

Cornelia de Lange syndrome: from molecular diagnosis to therapeutic approach

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Overexpression of the cohesin-core subunit SMC1A contributes to colorectal cancer development

Sarogni, P., Palumbo, O., Servadio, A., Astigiano, S., D’Alessio, B., Gatti, V., Cukrov, D., Baldari, S., Pallotta, M. M., Aretini, P., et al. (2019) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-019-1116-0 · Cited by 66 · see citing works

Genomic rearrangements induced by unscheduled DNA double strand breaks in somatic mammalian cells

So, A., Guen, T. L., López, B. S., & Guirouilh‐Barbat, J. (2017) · FEBS Journal · doi:10.1111/febs.14053 · Cited by 62 · see citing works

Cohesin SA1 and SA2 are RNA binding proteins that localize to RNA containing regions on DNA

Pan, H., Jin, M., Ghadiyaram, A., Kaur, P., Miller, H. E., Ta, H. M., Liu, M., Fan, Y., Mahn, C., Gorthi, A., et al. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa284 · Cited by 64 · see citing works

Single-cell multiregion epigenomic rewiring in Alzheimer’s disease progression and cognitive resilience

Liu, Z., Zhang, S., James, B. T., Galani, K., Mangan, R. J., Fass, S. B., Liang, C., Wagle, M. M., Boix, C. A., Tanigawa, Y., et al. (2025) · Cell · doi:10.1016/j.cell.2025.06.031 · Cited by 65 · see citing works

ATRX affects the repair of telomeric DSBs by promoting cohesion and a DAXX-dependent activity

Lovejoy, C. A., Takai, K., Huh, M. S., Picketts, D. J., & de Lange, T. (2020) · PLoS Biology · doi:10.1371/journal.pbio.3000594 · Cited by 61 · see citing works

Nuclear and genome dynamics underlying DNA double-strand break repair

Chiolo, I., Altmeyer, M., Legube, G., & Mekhail, K. (2025) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-025-00828-1 · Cited by 66 · see citing works

The multifaceted roles of cohesin in cancer

Nardo, M. D., Pallotta, M. M., & Musio, A. (2022) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-022-02321-5 · Cited by 58 · see citing works

ATM antagonizes NHEJ proteins assembly and DNA-ends synapsis at single-ended DNA double strand breaks

Britton, S., Chanut, P., Delteil, C., Barboule, N., Frit, P., & Calsou, P. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa723 · Cited by 59 · see citing works

Roles for APRIN (PDS5B) in homologous recombination and in ovarian cancer prediction

Couturier, A. M., Fleury, H., Patenaude, A., Bentley, V. L., Rodrigue, A., Coulombe, Y., Joshi, N., Pauty, J., Berman, J. N., Dellaire, G., et al. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkw921 · Cited by 54 · see citing works

Independent mechanisms recruit the cohesin loader protein NIPBL to sites of DNA damage

Bot, C., Pfeiffer, A., Giordano, F., Manjeera, D. E., Dantuma, N. P., & Ström, L. (2017) · Journal of Cell Science · doi:10.1242/jcs.197236 · Cited by 53 · see citing works

Cohesin SA2 is a sequence-independent DNA-binding protein that recognizes DNA replication and repair intermediates

Countryman, P. J., Fan, Y., Gorthi, A., Pan, H., Strickland, E., Kaur, P., Wang, X., Lin, J., Lei, X., White, C., et al. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m117.806406 · Cited by 49 · see citing works

Perturbing cohesin dynamics drives MRE11 nuclease-dependent replication fork slowing

Carvajal-Maldonado, D., Byrum, A. K., Jackson, J., Wessel, S. R., Lemacon, D. S., Guitton-Sert, L., Quinet, A., Tirman, S., Graziano, S., Masson, J., et al. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky519 · Cited by 40 · see citing works

RAD51 protects against nonconservative DNA double-strand break repair through a nonenzymatic function

So, A., Dardillac, E., Muhammad, A. A., Chailleux, C., Sesma-Sanz, L., Ragu, S., Cam, É. L., Canitrot, Y., Masson, J., Pauline, D., et al. (2022) · Nucleic Acids Research · doi:10.1093/nar/gkac073 · Cited by 35 · see citing works

The Molecular Mechanisms and Therapeutic Prospects of Alternative Lengthening of Telomeres (ALT)

Sohn, E. J., Goralsky, J. A., Shay, J. W., & Min, J. (2023) · Cancers · doi:10.3390/cancers15071945 · Cited by 34 · see citing works

In Favor of Establishment: Regulation of Chromatid Cohesion in Plants

Bolanos-Villegas, P. A., De, K., Pradillo, M., Liu, D., & Makaroff, C. A. (2017) · Frontiers in Plant Science · doi:10.3389/fpls.2017.00846 · Cited by 34 · see citing works

Prevalence of Mutation-Prone Microhomology-Mediated End Joining in a Chordate Lacking the c-NHEJ DNA Repair Pathway

Deng, W., Henriet, S., & Chourrout, D. M. (2018) · Current Biology · doi:10.1016/j.cub.2018.08.048 · Cited by 34 · see citing works

Genome stability: What we have learned from cohesinopathies

Cucco, F., & Musio, A. (2016) · American Journal of Medical Genetics Part C Seminars in Medical Genetics · doi:10.1002/ajmg.c.31492 · Cited by 34 · see citing works

Chromatin recruitment of OGG1 requires cohesin and mediator and is essential for efficient 8-oxoG removal

Lebraud, E., Pinna, G., Siberchicot, C., Dépagne, J., Busso, D., Fantini, D., Irbah, L., Robeska, E., Kratassiouk, G., Ravanat, J., et al. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa611 · Cited by 32 · see citing works

53BP1 Protects against CtIP-Dependent Capture of Ectopic Chromosomal Sequences at the Junction of Distant Double-Strand Breaks

Guirouilh‐Barbat, J., Gelot, C., Xie, A., Dardillac, E., Scully, R., & López, B. S. (2016) · PLoS Genetics · doi:10.1371/journal.pgen.1006230 · Cited by 31 · see citing works

PHF6 promotes non‐homologous end joining and G2 checkpoint recovery

Warmerdam, D. O., Vega, I. A., Wiegant, W. W., van den Broek, B., Rother, M. B., Wolthuis, R. M. F., Freire, R., van Attikum, H., Medema, R. H., & Smits, V. A. J. (2019) · EMBO Reports · doi:10.15252/embr.201948460 · Cited by 31 · see citing works

Rpd3L and Hda1 histone deacetylases facilitate repair of broken forks by promoting sister chromatid cohesion

Ortega, P., Gómez‐González, B., & Aguilera, A. (2019) · Nature Communications · doi:10.1038/s41467-019-13210-5 · Cited by 29 · see citing works

New insights into cohesin loading

Litwin, I., & Wysocki, R. (2017) · Current Genetics · doi:10.1007/s00294-017-0723-6 · Cited by 28 · see citing works

Function and Evolution of the Loop Extrusion Machinery in Animals

Kabirova, E., Nurislamov, A. R., Shadskiy, A., Smirnov, A. V., Popov, A., Salnikov, P., Баттулин, Н. Р., & Fishman, V. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24055017 · Cited by 25 · see citing works

Separase prevents genomic instability by controlling replication fork speed

Cucco, F., Palumbo, E., Camerini, S., D’Alessio, B., Quarantotti, V., Casella, M., Rizzo, I. M., Cukrov, D., Delia, D., Russo, A., et al. (2017) · Nucleic Acids Research · doi:10.1093/nar/gkx1172 · Cited by 26 · see citing works

Cohesin dynamic association to chromatin and interfacing with replication forks in genome integrity maintenance

Villa‐Hernández, S., & Bermejo, R. (2018) · Current Genetics · doi:10.1007/s00294-018-0824-x · Cited by 22 · see citing works

Recombination-mediated genome rearrangements

Savocco, J., & Piazza, A. (2021) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2021.06.008 · Cited by 20 · see citing works

A dual role of Cohesin in DNA DSB repair

Fedkenheuer, M., Shang, Y., Jung, S., Fedkenheuer, K., Park, S., Mazza, D., Sebastian, R., Nagashima, H., Zong, D., Tan, H., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-56086-4 · Cited by 20 · see citing works

Sweet Melody or Jazz? Transcription Around DNA Double-Strand Breaks

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RAD21 Confers Poor Prognosis and Affects Ovarian Cancer Sensitivity to Poly(ADP-Ribose)Polymerase Inhibitors Through DNA Damage Repair

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A Link between Replicative Stress, Lamin Proteins, and Inflammation

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Cohesin complex oligomerization maintains end-tethering at DNA double-strand breaks

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In vivo reduction of RAD51‐mediated homologous recombination triggers aging but impairs oncogenesis

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Laser Microirradiation to Study In Vivo Cellular Responses to Simple and Complex DNA Damage

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Emerging roles of cohesin-STAG2 in cancer

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Doxorubicin Changes the Spatial Organization of the Genome around Active Promoters

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BRD2 promotes antibody class switch recombination by facilitating DNA repair in collaboration with NIPBL

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Roles for the 3D genome in the cell cycle, DNA replication, and double strand break repair

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Polymer perspective of genome mobilization

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INT6/EIF3E Controls the RNF8-Dependent Ubiquitylation Pathway and Facilitates DNA Double-Strand Break Repair in Human Cells

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Disease-associated c-MYC downregulation in human disorders of transcriptional regulation

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Cohesin-Dependent Loop Extrusion: Molecular Mechanics and Role in Cell Physiology

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Cohesin RAD21 Gene Promoter Methylation in Patients with Chronic Lymphocytic Leukemia

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Reduced sister chromatid cohesion acts as a tumor penetrance modifier

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Persistent STAG2 mutation despite multimodal therapy in recurrent pediatric glioblastoma

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The Use of Laser Microirradiation to Investigate the Roles of Cohesins in DNA Repair

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A genetic interaction map centered on cohesin reveals auxiliary factors in sister chromatid cohesion

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The Role of Methylation in Chronic Lymphocytic Leukemia and Its Prognostic and Therapeutic Impacts in the Disease: A Systematic Review

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Mutations that prevent methylation of cohesin render sensitivity to DNA damage in S. pombe

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The Influence of Cohesin on the Short-Scale Dynamics of Intact and Damaged Chromatin in Different Phases of the Cell Cycle

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Cohesin RAD21 Gene Promoter Methylation in Patients with Acute Myeloid Leukemia

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Novel CRISPR/Cas9-Based Approaches for Quantitative Study of DSB Repair Mechanics

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The Cohesion complex maintains genome stability by preventing end joining of distant DNA ends in S phase

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Chl1 helicase controls replication fork progression by regulating dNTP pools

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Effect of Helicobacter pylori on non-homologous end joining-mediated repair of proximal DNA double-strand breaks in GCV6 cells

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Genome rearrangements induced by the stimulation of end-joining of DNA double strand breaks through multiple phosphorylation of MRE11 by the kinase PKB/AKT1

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A nucleoskeleton network preserves genomic integrity by promoting NHEJ and restraining chromosome translocations

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Folding a broken genome: the versatile roles of cohesin in genome maintenance

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Special issue: Nuclear architecture and chromatin motions in the DNA damage response

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RAD51 promotes non-homologous genetic rearrangements that are prevented by 53BP1Preprint

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The Application of Proteomics and Phosphoproteomics to Reveal the Molecular Mechanism of Salidroside in Ameliorating Myocardial HypoxiaPreprint

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Faculty Opinions recommendation of Loop extrusion as a mechanism for formation of DNA damage repair foci.

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PKA prevents resection of DNA double strand breaks and favor non-homologous end-joiningPreprint

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Cohesin-dependent loop extrusion: molecular mechanics and role in cell physiology

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ALT-EJ GENERA REARREGLOS CROMOSÓMICOS EN RESPUESTA A ETOPÓSIDO EN CÉLULAS HUMANAS CON LOS PRINCIPALES SISTEMAS DE REPARACIÓN DE RUPTURAS DE DOBLE CADENA COMPROMETIDOS

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The multiscale distribution of radiation-induced DNA damage and its impact on local genome structurePreprint

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PKA prevents the resection of DNA double-strand breaks and favours nonhomologous end-joining

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RaDRI: A computational model for radiosensitisation by DNA double strand break repair inhibitorsPreprint

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RAD51 Protects Against RAD52-Dependent Non-Conservative Double-Strand Break Repair Processes, by Impeding the Annealing Step

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Régulation de la résection aux cassures double-brin par l'hétérochromatine SIR dépendante

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Régulation des étapes précoces de la recombinaison homologue humaine par BRCA2 et RAD52

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Origins of Cellular Lethality Resulting From a Defect in Homologous Recombination in Human Cells

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Mécanismes de contrôle du complexe MRX aux télomères

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Implication de glycosyltransférases dans la tumorigenèse colorectale : POFUT1 et ST3GAL2

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Implications de la lamine B1 dans la stabilité des télomères et la mitose

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L'implication des hybrides ADN : ARN et de la modification m6A des ARN dans la réparation des cassures double-brins de l'ADN

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PAXIP1-PAGR1 directs cohesin recruitment during break-induced telomere repairPreprint

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The cohesin complex prevents the end-joining of distant DNA double-strand ends in S phase: Consequences on genome stability maintenance

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The Cohesion complex maintains genome stability by preventing end joining of distant DNA ends in S phase

Gelot, C., Guirouilh‐Barbat, J., & López, B. S. (2016) · Molecular & Cellular Oncology · doi:10.1080/23723556.2016.1154123 · Cited by 2 · see citing works

The cohesin complex protects against genome rearrangements by preventing the end-joining of distal DNA double-strand-ends

Gelot, C. (2014) · theses.fr (ABES)

Cohesin complex oligomerization maintains end-tethering at DNA double-strand breaks

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Cohesin Does the Business

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