A Compact, High-Accuracy Cas9 with a Dinucleotide PAM for In Vivo Genome Editing
Edraki, Alireza, Mir, Aamir, Ibraheim, Raed, Gainetdinov, Ildar, Yoon, Yeonsoo, Song, Chun-Qing, Cao, Yueying, Gallant, Judith, Xue, Wen, Rivera-Pérez, Jaime A., Sontheimer, Erik J.·2019·Molecular Cell
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- A quantitative model for the dynamics of target recognition and off-target rejection by the CRISPR-Cas Cascade complexMarius Rutkauskas, Inga Songailienė, Patrick Irmisch, Felix E. Kemmerich, Tomas Šinkūnas, Virginijus Šikšnys, Ralf Seidel · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
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- PAM-readID is a rapid, simple, and accurate PAM determination method for CRISPR-Cas enzymes in mammalian cellsQiuyan Wang, Zhuang Wang, Huiyu Liu, Yawen Lv, Changli Zhou, Chenglu Li, Hui-Qin Fan, Xi Ouyang, Lin Tao, Xiaolin Pei et al. · 2025 · Communications Biology
- Structural and functional insights into internal domain replacement in SpCas9 for protein engineeringSeonhong Kim, Hyuk Won, Jungnam Bae, Jeesoo Kim, Jin‐Hyuk Choi, Halimriadi Richar, Yang‐Gyun Kim, Hee‐Jung Choi · 2025 · Scientific Reports
- CasMiner: a deep-learning tool for high-throughput mining and rational design of efficient Cas9Guoshun Xu, Suzhen Li, Haoyu Li, Xiaopu Ren, Yekun Ding, Xinli Pang, Xiaohu Liu, Qiaoling Tang, Tao Tu, Yuan Wang et al. · 2026 · National Science Review
- Spatially concentrated adenine base editors efficiently correct PLP1 mutations in oligodendrocytesChi Zhang, Ke Ye, Yafang Shang, Yixuan Song, Pingping Li, Xinyue Jiang, Cuiping Yang, Aibin Liang, Jian Zhang, Fei‐Long Meng et al. · 2026 · Nucleic Acids Research
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- The CRISPR/Cas-associated scaRNA modulates efeUOB expression and stress responses in Neisseria meningitidisDenise Pytlik, Milan Gerovac, Thorsten Bischler, Andreas Schlösser, Jörg Vogel, Christoph U. Schoen · 2026 · microLife
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- Translating base editors: a decade of progress from the bench to the clinicNicole M. Gaudelli, Alexis C. Komor · 2026 · Nature Reviews Drug Discovery
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- A multifunctional Wnt regulator underlies the evolution of coat pattern in African striped miceM. R. Johnson, Sha Li, C. Guerrero-Juarez, Pearson Miller, Benjamin J. Brack, Sarah A. Mereby, Charles Y. Feigin, Jenna M. Gaska, Qing Nie, J. Rivera-Pérez et al. · 2023 · bioRxiv
- DeepEmbCas9: Cas9 coevolution and sgRNA structural information for CRISPR-Cas9 cleavage activity predictionJeffrey Kelvin Mak, Péter Mináry · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- CRISPR-Cas Systems Reduced to a MinimumCristóbal Almendros, Sebastian N. Kieper, Stan J. J. Brouns · 2019 · Molecular Cell
- Development of therapeutic genome engineering in laminin-α2-deficient congenital muscular dystrophyDwi U. Kemaladewi, Ronald D. Cohn · 2019 · Emerging Topics in Life Sciences
- Modulating the activity of CRISPR/Cas9 genome editing by small moleculesSiwei Chen · 2021
- 神先先生の古稀及び定年を迎えられるにあたって (神先秀雄・薄田桂・友松芳郎三教授古稀記念特輯)宏 井上 · 1981 · 関西大学社会学部紀要
- Faculty Opinions recommendation of Inhibition of histone deacetylase 1 (HDAC1) and HDAC2 enhances CRISPR/Cas9 genome editing.Yousin Suh · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- CRISPR CasSaša Šviković · 2022 · Wiley eBooks
- Computational Tools for Target Design and AnalysisGue‐Ho Hwang, Sangsu Bae · 2022 · Wiley eBooks
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- Quantitative assaying of SpCas9-NG with fluorescent reportersAlexandre Baccouche, Kévin Montagne, Nozomu Yachie, Teruo Fujii, Anthony J. Genot · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Molecular Mechanisms of Type II CRISPR ‐ Cas SystemsTautvydas Karvelis, Virginijus Šikšnys · 2022 · Wiley eBooks
- Engineering Nme2Cas9 Adenine Base Editors with Improved Activity and Targeting ScopeNathan Bamidele, Han Zhang, Xiaolong Dong, Nicholas Gaston, Haoyang Cheng, Karen L. Kelly, Jonathan K. Watts, Jun Xie, Guangping Gao, Erik J. Sontheimer · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- EDSpliCE, a CRISPR-Cas9 gene editing platform to rescue splicing, effectively corrects inherited retinal dystrophy-associated splicing defectsPietro De Angeli, Stefanida Shliaga, Arturo Flores-Tufiño, Eleonora Roschi, Salome Spaag, Katarína Štingl, Laura Kuehlewein, Bernd Wissinger, Susanne Kohl · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Gene Expression and Editing in Mammalian Retinal Ganglion CellsNicholas M. Tran, Xiaoshu Xu, Lei S. Qi, Yang Hu · 2024 · Essentials in ophthalmology/Essentials ophthalmology
- Characterization of the genome editing with miniature nucleases TnpB, IscB and enIscB in Escherichia coli strainsHongjie Tang, Jie Gao, Mingjun Sun, Suyi Zhang, Qi Li · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- CRISPR/Cas9-based genetic engineering for translational research in neurological disordersPlaton Megagiannis, Guy Armand Rouleau, Yang Zhou · 2024 · Elsevier eBooks
- Rational Design of Enhanced Nme2Cas9 and Nme2 Smu Cas9 Nucleases and Base EditorsNathan Bamidele, Aditya Valji Ansodaria, Zexiang Chen, Haoyang Cheng, Rebecca Panwala, Eva Jazbec, Erik J. Sontheimer · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Nano-Polymers as Cas9 InhibitorsOksana M. Chepurna, Avradip Chatterjee, Yuan‐Qing Li, Hong Ding, Ramachandran Murali, Keith L. Black, Tao Sun · 2025 · Polymers
- Machine learning-driven optimization of specific, compact, and efficient base editors via single-round diversificationMykyta Ielanskyi, Meng Wang, Lewis Scott, Lila Rieber, Stephanie L. Merrett, Johannes Schimunek, Andreas Mayr, Ian C. McDowell, Günter Klambauer, Tyson Bowen · 2026 · Nucleic Acids Research
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- Double-stranded DNA deaminase DddAE1347A can increase the efficiency and targeting range of cytidine base editorsYuqiang Qian, Fengjiao Hui, Wenchao Niu, Di Wang, Yang Hao, Qingying Meng, Siyu Ren, Deqiang Kong, Heng Gong, Jiayu Wu et al. · 2025 · Genome biology
- Additional file 2 of Engineered domain-inlaid Nme2Cas9 adenine base editors with increased on-target DNA editing and targeting scopeDing Zhao, Gao, Xun, Zhou, Jiale, Li, Jinze, Yuqiang Qian, Wang, Di, Niu, Wenchao, Zhang, Tao, Hu, Mingyang, Haoyang Xiong et al. · 2024 · Figshare
- Additional file 3 of Engineered domain-inlaid Nme2Cas9 adenine base editors with increased on-target DNA editing and targeting scopeDing Zhao, Gao, Xun, Zhou, Jiale, Li, Jinze, Yuqiang Qian, Wang, Di, Niu, Wenchao, Tao Zhang, Hu, Mingyang, Haoyang Xiong et al. · 2024 · Figshare
- Additional file 1 of Short cell-penetration peptide conjugated bioreducible polymer enhances gene editing of CRISPR systemXiaobo Wang, Chengyuan Cai, Weiqi Lv, Kechen Chen, Li, Jiaxin, Kaitong Liao, Zhang, Yanqun, Huang, Hongxin, Lin, Ying, Rong, Zhili et al. · 2024 · Figshare
- Additional file 1 of Engineered domain-inlaid Nme2Cas9 adenine base editors with increased on-target DNA editing and targeting scopeDing Zhao, Gao, Xun, Zhou, Jiale, Li, Jinze, Yuqiang Qian, Wang, Di, Niu, Wenchao, Tao Zhang, Hu, Mingyang, Haoyang Xiong et al. · 2023 · Figshare
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- Compact 9dBEs Enable Efficient and Precise Genome Editing in Mammalian Cells and In VivoQingquan Xiao, Zhijin Tian, Luqi Weng, Kun Xu, Dingyi Han, Zhaowei Wu, Junnan Li, Shangpu Li, Qijing Zhang, Xiaohui Zhao et al. · 2026 · Advanced Science
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