Song, Chun-Qing

Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo

Yin, H., Song, C.-Q., Dorkin, J. R., Zhu, L. J., Li, Y., Wu, Q., Park, A., Yang, J., Suresh, S., Bizhanova, A., et al. (2016) · Nature Biotechnology

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 876

Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing

Yin, H., Song, C.-Q., Suresh, S., Wu, Q., Walsh, S., Rhym, L. H., Mintzer, E., Bolukbasi, M. F., Zhu, L. J., Kauffman, K., et al. (2017) · Nature Biotechnology

CRISPR and Genetic EngineeringRNA Interference and Gene Delivery

Cited by 499

A compact, high-accuracy Cas9 with a dinucleotide PAM for in vivo genome editing

Edraki, A., Mir, A., Ibraheim, R., Gainetdinov, I., Yoon, Y., Song, C.-Q., Cao, Y., Gallant, J., Xue, W., Rivera-Pérez, J. A., et al. (2019) · Molecular Cell

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 265

Partial DNA-guided Cas9 enables genome editing with reduced off-target activity

Yin, H., Song, C.-Q., Suresh, S., Kwan, S.-Y., Wu, Q., Walsh, S., Ding, J., Bogorad, R. L., Zhu, L. J., Wolfe, S. A., et al. (2018) · Nature Chemical Biology

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 240

Adenine base editing in an adult mouse model of tyrosinaemia

Song, C.-Q., Jiang, T., Richter, M., Rhym, L. H., Koblan, L. W., Zafra, M. P., Schatoff, E. M., Doman, J. L., Cao, Y., Dow, L. E., et al. (2019) · Nature Biomedical Engineering

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 200

Genetic disruption of oncogenic Kras sensitizes lung cancer cells to Fas receptor-mediated apoptosis

Mou, H., Moore, J., Malonia, S. K., Li, Y., Ozata, D. M., Hough, S., Song, C.-Q., Smith, J. L., Fischer, A., Weng, Z., et al. (2017) · Proceedings of the National Academy of Sciences

Protein Kinase Regulation and GTPase SignalingCell death mechanisms and regulation

Cited by 46

Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target-silencing

Li, Z., Li, Z., Li, L., Zeng, L., Xue, J., Niu, H., Zhong, J., Yu, Q., Li, D., Tu, S., et al. (2023) · Nature Structural & Molecular Biology

RNA Interference and Gene DeliveryChromosomal and Genetic Variations

Cited by 35

Mammalian PIWI–piRNA–target complexes reveal features for broad and efficient target silencing

Li, Z., Li, Z., Zhang, Y., Zhou, L., Xu, Q., Li, L., Zeng, L., Xue, J., Niu, H., Zhong, J., et al. (2024) · Nature Structural & Molecular Biology

RNA Interference and Gene DeliveryChromosomal and Genetic Variations

Cited by 35