RNA Circularization Diminishes Immunogenicity and Can Extend Translation Duration In Vivo

Wesselhoeft, R. Alexander, Kowalski, Piotr S., Parker-Hale, Frances C., Huang, Yuxuan, Bisaria, Namita, Anderson, Daniel G.·2019·Molecular Cell

Cited by (487)

Items 101–200 of 487

  1. A flexible, efficient, and scalable platform to produce circular RNAs as new therapeutics
    Huanhuan Y. Wei, Chuyun Chen, Kai Zhang, Zeyang Li, Tong Wei, Chenxiang Tang, Yun Yang, Zefeng Wang · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  2. Circular RNA: A novel potential biomarker for skin diseases
    Xiaoting Wu, Yanwei Xiao, Jingxin Ma, Aoxue Wang · 2020 · Pharmacological Research
  3. Research progress on circular RNA vaccines
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  4. Functions of Circular RNA in Human Diseases and Illnesses
    Gu, Alison, Jaijyan, Dabbu Kumar, Yang, Shaomin, Zeng, Mulan, Pei, Shaokai, Zhu, Hua · 2023 · Non-Coding RNA
  5. Circular RNA in disease: Basic properties and biomedical relevance
    Xiaolan Chen, Min Zhou, Levi J Yant, Chuan Huang · 2022 · Wiley Interdisciplinary Reviews - RNA
  6. mRNA vaccines contribute to innate and adaptive immunity to enhance immune response in vivo
    Qiannan Cao, Huapan Fang, Huayu Tian · 2024 · Biomaterials
  7. Rational design of microRNA-responsive switch for programmable translational control in mammalian cells
    Hui Ning, Gan Liu, Lei Li, Qiang Liu, Huiya Huang, Zhen Xie · 2023 · Nature Communications
  8. Host-derived circular RNAs display proviral activities in Hepatitis C virus-infected cells
    Tzu‐Chun Chen, Marc Talló-Parra, Qian M. Cao, Sebastián Kadener, René Böttcher, Gemma Pérez‐Vilaró, Pakpoom Boonchuen, Kunlaya Somboonwiwat, Juana Díez, Peter Sarnow · 2020 · PLoS Pathogens
  9. Lipid Nanoparticle Delivery System for mRNA Encoding B7H3‐redirected Bispecific Antibody Displays Potent Antitumor Effects on Malignant Tumors
    Cheng Huang, Xing Duan, Jichao Wang, Qingqing Tian, Yangmei Ren, Kepan Chen, Zongliang Zhang, Yuanyou Li, Yunyu Feng, Kunhong Zhong et al. · 2022 · Advanced Science
  10. Optimized circular RNA vaccines for superior cancer immunotherapy
    Hongwu Yu, Yifan Wen, Wenqian Yu, Liang Lu, Yu Yang, Chengye Liu, Zhixiang Hu, Zhuting Fang, Shenglin Huang · 2024 · Theranostics
  11. Circular RNAs in cell differentiation and development
    Gaia Di Timoteo, Francesca Rossi, Irene Bozzoni · 2020 · Development
  12. Therapeutic mRNA Engineering from Head to Tail
    Longfei Jia, Shu‐Bing Qian · 2021 · Accounts of Chemical Research
  13. Efficient circular RNA synthesis for potent rolling circle translation
    Yifei Du, Philipp Konrad Zuber, Huajuan Xiao, Xueyan Li, Yuliya Gordiyenko, Venki Ramakrishnan · 2024 · Nature Biomedical Engineering
  14. Viruses join the circular RNA world
    Ke‐En Tan, Yat‐Yuen Lim · 2020 · FEBS Journal
  15. mRNA vaccines in the prevention and treatment of diseases
    Yangzhuo Gu, Jiangyao Duan, Na Yang, Yuxin Yang, Xing Zhao · 2022 · MedComm
  16. Recent advances and perspectives on the development of circular RNA cancer vaccines
    Zhaohui Gong, Wentao Hu, Chengwei Zhou, Jing Guo, Lulu Yang, Boyang Wang · 2025 · npj Vaccines
  17. Engineered exosomes as drug and RNA co-delivery system: new hope for enhanced therapeutics?
    Haorong Chen, Hanbo Yao, Jiaxin Chi, Chaowei Li, Yilin Liu, Yang Jiayi, Jiaqi Yu, Jiajun Wang, Yongdui Ruan, Jiang Pi et al. · 2023 · Frontiers in Bioengineering and Biotechnology
  18. Why rings of RNA could be the next blockbuster drug
    Elie Dolgin · 2023 · Nature
  19. Cellular Trafficking of Nanotechnology‐Mediated mRNA Delivery
    Pei Huang, Hongzhang Deng, Changrong Wang, Yongfeng Zhou, Xiaoyuan Shawn Chen · 2023 · Advanced Materials
  20. Advances in the design and delivery of RNA vaccines for infectious diseases
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  21. Intranasal prime-boost RNA vaccination elicits potent T cell response for lung cancer therapy
    Hongjian Li, Yating Hu, Jingxuan Li, Jia He, Guocan Yu, Jiasheng Wang, Xin Lin · 2025 · Signal Transduction and Targeted Therapy
  22. Biological functions and applications of circRNAs—next generation of RNA-based therapy
    Meiling Sun, Yun Yang · 2023 · Journal of Molecular Cell Biology
  23. SARS‐CoV‐2, SARS‐CoV, and MERS‐CoV encode circular RNAs of spliceosome‐independent origin
    Shaomin Yang, Hong Zhou, Mingde Liu, Dabbu Kumar Jaijyan, Ruth Cruz‐Cosme, Santhamani Ramasamy, Selvakumar Subbian, Dongxiao Liu, Jiayu Xu, Xiaoyu Niu et al. · 2022 · Journal of Medical Virology
  24. Polyplex designs for improving the stability and safety of RNA therapeutics
    Satoshi Uchida, Chun Yin Jerry Lau, Makoto Oba, Kanjiro Miyata · 2023 · Advanced Drug Delivery Reviews
  25. Exogenous RNA surveillance by proton-sensing TRIM25
    Myeonghwan Kim, Youngjoon Pyo, Seong‐In Hyun, Minseok Jeong, Yeon Choi, V. Narry Kim · 2025 · Science
  26. Nanotechnology-enabled immunoengineering approaches to advance therapeutic applications
    Skylar T. Chuang, Brandon Conklin, Joshua B. Stein, George Pan, Ki‐Bum Lee · 2022 · Nano Convergence
  27. Lipid nanoparticle (LNP) mediated mRNA delivery in neurodegenerative diseases
    Seyedeh Ghazal Moosavi, Niloufar Rahiman, Mahmoud Reza Jaafari, Leila Arabi · 2025 · Journal of Controlled Release
  28. Research progress on the quality control of mRNA vaccines
    Chaoying Hu, Yu Bai, Jianyang Liu, Yiping Wang, Qian He, Xuanxuan Zhang, Feiran Cheng, Miao Xu, Qunying Mao, Zhenglun Liang · 2024 · Expert Review of Vaccines
  29. Optimal design of synthetic circular RNAs
    Seo-Won Choi, Jin‐Wu Nam · 2024 · Experimental & Molecular Medicine
  30. Signal and noise in circRNA translation
    Thomas B. Hansen · 2021 · Methods
  31. Nanoscale delivery platforms for RNA therapeutics: Challenges and the current state of the art
    Luke H. Rhym, Daniel G. Anderson · 2022 · Med
  32. RNA editing of microtubule-associated protein tau circular RNAs promotes their translation and tau tangle formation
    Justin Ralph Welden, Giorgi Margvelani, Karol Andrea Arizaca Maquera, Bhavani Gudlavalleti, Sandra C. Miranda Sardón, Alexandre Rosa Campos, Noémie Robil, Daniel C. Lee, Alvaro Gonzalo Hernandez, Wang‐Xia Wang et al. · 2022 · Nucleic Acids Research
  33. Approaches and challenges in genome-wide circular RNA identification and quantification
    Xu-Kai Ma, Si-Nan Zhai, Li Chun Yang · 2023 · Trends in Genetics
  34. In silico analysis and comprehensive review of circular-RNA regulatory roles in breast diseases; a step-toward non-coding RNA precision
    Nadia Μ. Hamdy, Mona G El-Sisi, Sherine M. Ibrahim, Heba ElNokoudy, Ahmad A. Hady, Gamal Eldein Fathy Abd-Ellatef, Al-Aliaa M. Sallam, Bassant Mohamed Barakat · 2024 · Pathology - Research and Practice
  35. Progress on the pathological tissue microenvironment barrier-modulated nanomedicine
    Han Han, Lei Xing, Bi‐Te Chen, Yang Liu, Tian‐Jiao Zhou, Yi Wang, Lingfeng Zhang, Ling Li, Chong‐Su Cho, Hu‐Lin Jiang · 2023 · Advanced Drug Delivery Reviews
  36. circRNA: A Promising All-Around Star in the Future
    Hanlin Li · 2023 · Epigenomics
  37. Circular RNAs in neurological conditions – computational identification, functional validation, and potential clinical applications
    Oak Hatzimanolis, Alex M. Sykes, Alexandre S. Cristino · 2025 · Molecular Psychiatry
  38. CircRNA: An emerging star in the progression of glioma
    Dazhao Peng, Lin Luo, Xiaoyang Zhang, Cheng Wei, Zhenyu Zhang, Lei Han · 2022 · Biomedicine & Pharmacotherapy
  39. Critical function of circular RNAs in lung cancer
    Rareş Drulă, Cornelia Braicu, Antonia Haranguș, Seyed Mohammad Nabavi, Monica Trif, Ondřej Slabý, Călin Ionescu, Alexandru Irimie, Ioana Berindan‐Neagoe · 2020 · Wiley Interdisciplinary Reviews - RNA
  40. In Vitro Transcribed RNA-Based Platform Vaccines: Past, Present, and Future
    Alexey D. Perenkov, Alena D. Sergeeva, Maria V. Vedunova, Dmitri V. Krysko · 2023 · Vaccines
  41. Engineering circular RNA medicines
    Xiaofei Cao, Zhengyi Cai, Jinyang Zhang, Fangqing Zhao · 2024 · Nature Reviews Bioengineering
  42. Chemically synthesized circular RNAs with phosphoramidate linkages enable rolling circle translation
    Kosuke Nakamoto, Naoko Abe, Genichiro Tsuji, Yasuaki Kimura, Fumiaki Tomoike, Yoshihiro Shimizu, Hiroshi Abe · 2020 · Chemical Communications
  43. How RNA modifications regulate the antiviral response
    Matthew G. Thompson, Matthew T. Sacco, Stacy M. Horner · 2021 · Immunological Reviews
  44. A precise and efficient circular RNA synthesis system based on a ribozyme derived from Tetrahymena thermophila
    Jingyi Cui, Lanxin Zhang, Zaifeng Zhang, Xuanmei Luo, Ye Liu, Chang Li, Wei Huang, Lihui Zou, Xue Min Yu, Fei Xiao · 2023 · Nucleic Acids Research
  45. Circular RNAs in human diseases
    Yuanyong Wang, Jin Zhang, Yu‐Chen S. H. Yang, Zhuofeng Liu, Sijia Sun, Rui Fang Li, Hui Zhu, Li Tian, Jin Zheng, Jie Li et al. · 2024 · MedComm
  46. Scarless circular mRNA-based CAR-T cell therapy elicits superior antitumor efficacy
    Qinchao Hu, Hui Zhao, Kaicheng Zhou, Xuefei Tian, Q Z Wang, Xianxin Hua, Xuyao Zhang · 2025 · Signal Transduction and Targeted Therapy
  47. RNA-based therapy for osteogenesis
    Pinpin Wang, Federico Perche, Delphine Logeart‐Avramoglou, Chantal Pichon · 2019 · International Journal of Pharmaceutics
  48. Reinventing the Wheel: Synthetic Circular RNAs for Mammalian Cell Engineering
    Alan Costello, Nga Thi Lao, Niall Barron, MARTIN M. CLYNES · 2019 · Trends in biotechnology
  49. Circular RNA-based therapy provides sustained and robust neuroprotection for retinal ganglion cells
    Wenbing Jiang, Dongchang Xiao, Cheng Wu, Jiaqi Yang, Xinghua Peng, Linfeng Chen, Jiamin Zhang, Gao-Feng Zha, Wei Li, Rong Ju et al. · 2024 · Molecular Therapy — Nucleic Acids
  50. Synthetic circRNA therapeutics: innovations, strategies, and future horizons
    Jingsheng Cai, Zonghao Qiu, William Chi Shing Cho, Zheng Liu, Shaoyi Chen, Haoran Li, Kezhong Chen, Yun Li, Chijian Zuo, Mantang Qiu · 2024 · MedComm
  51. Internal cap-initiated translation for efficient protein production from circular mRNA
    Kosuke Fukuchi, Yuko Nakashima, Naoko Abe, Seigo Kimura, Fumitaka Hashiya, Yuichi Shichino, Yiwei Liu, Ryoko Ogisu, Satomi Sugiyama, Daisuke Kawaguchi et al. · 2025 · Nature Biotechnology
  52. Function of Circular RNAs in Fish and Their Potential Application as Biomarkers
    Golam Rbbani, Artem Nedoluzhko, Jorge Galindo‐Villegas, Jorge M. O. Fernandes · 2021 · International Journal of Molecular Sciences
  53. Demystifying mRNA vaccines: an emerging platform at the forefront of cryptic diseases
    Nusrat Zahan Rouf, Sumit Biswas, Nawseen Tarannum, Labiba Mustabina Oishee, Mutia Masuka Muna · 2022 · RNA Biology
  54. Innate immunity in hepatitis B and D virus infection: consequences for viral persistence, inflammation, and T cell recognition
    M. Dandri, A. Bertoletti, M. Lütgehetmann · 2021 · Seminars in Immunopathology
  55. Application prospect of circular RNA-based neoantigen vaccine in tumor immunotherapy
    Mohan Li, Yian Wang, Pan Wu, Shan Zhang, Zhaojian Gong, Qianjin Liao, Can Guo, Fuyan Wang, Yong Li, Zhaoyang Zeng et al. · 2023 · Cancer Letters
  56. Insights into the role of circular RNA in macrophage activation and fibrosis disease
    Mengxue Xu, Feiting Xie, Xinyi Tang, Tingting Wang, Sheng-Jun Wang · 2020 · Pharmacological Research
  57. What goes around comes around: Artificial circular RNAs bypass cellular antiviral responses
    Janina Breuer, Patrick Barth, Yannic Noe, Lyudmila A. Shalamova, Alexander Goesmann, Friedemann Weber, Oliver Roßbach · 2022 · Molecular Therapy — Nucleic Acids
  58. Circular mRNA-based TCR-T offers a safe and effective therapeutic strategy for treatment of cytomegalovirus infection
    Lianghua Shen, Jiali Yang, Chijian Zuo, Jian Xu, Ling Ma, Qiaomei He, Xiao Zhou, Xiaodan Ding, Lixiang Wei, Suqin Jiang et al. · 2023 · Molecular Therapy
  59. Circular RNA vaccines: Pioneering the next-gen cancer immunotherapy
    Uddalak Das, Soupayan Banerjee, Meghna Sarkar, Fathah Muhammad L, Tanveen Kaur Soni, Madhumita Saha, Gayatri Pradhan, Bhaskarjyaa Chatterjee · 2024 · Cancer Pathogenesis and Therapy
  60. Synthetic circular miR-21 RNA decoys enhance tumor suppressor expression and impair tumor growth in mice
    Simon Müller, Alice Wedler, Janina Breuer, Markus Glaß, Nadine Bley, Marcell Lederer, Jacob Haase, Claudia Misiak, Tommy Fuchs, Alina Ottmann et al. · 2020 · NAR Cancer
  61. PGM5-AS1 impairs miR-587-mediated GDF10 inhibition and abrogates progression of prostate cancer
    Lei Du, Yongli Gao · 2021 · Journal of Translational Medicine
  62. The infinite possibilities of RNA therapeutics
    Evelyn Carolina Mollocana Lara, Ming Ni, Spiros Nicolas Agathos, Fernando Alexis Gonzales-Zubiate · 2021 · Journal of Industrial Microbiology & Biotechnology
  63. Intricate confrontation: Research progress and application potential of TRIM family proteins in tumor immune escape
    Junjie Gu, Jingyi Chen, Shuaixi Xiang, Xikun Zhou, Jing Li · 2023 · Journal of Advanced Research
  64. CircRNAs: functions and emerging roles in cancer and immunotherapy
    Yan Wang, Yanru Cui, Xin Li, Su‐Han Jin, Haitao Wang, Udo S. Gaipl, Hu Ma, Shixiang Wang, Jian‐Guo Zhou · 2025 · BMC Medicine
  65. miR-142: A Master Regulator in Hematological Malignancies and Therapeutic Opportunities
    Wilson Huang, Doru Paul, George A. Călin, Recep Bayraktar · 2023 · Cells
  66. The Role of N6-Methyladenosine Modified Circular RNA in Pathophysiological Processes
    Mei Tang, Yonggang Lv · 2021 · International Journal of Biological Sciences
  67. Small circular interfering RNAs (sciRNAs) as a potent therapeutic platform for gene-silencing
    Hartmut Jahns, Rohan Degaonkar, Peter Podbevšek, Swati Gupta, Anna Bisbe, Krishna Chaitanya Aluri, John Szeto, Pawan Kumar, Sarah LeBlanc, Tim Racie et al. · 2021 · Nucleic Acids Research
  68. RNA therapeutics for cardiovascular disease
    Christian Boada, Roman A. Sukhovershin, Roderic Ivan Pettigrew, John P. Cooke · 2021 · Current Opinion in Cardiology
  69. Robust genome and cell engineering via in vitro and in situ circularized RNAs
    Michael Tong, Nathan D. Palmer, Amir Dailamy, Aditya Kumar, Hammza Khaliq, Sangwoo Han, Emma N Finburgh, Madeleine K. Wing, Camilla Hong, Yichen Xiang et al. · 2024 · Nature Biomedical Engineering
  70. Dynamic conformation: Marching toward circular RNA function and application
    Chu‐Xiao Liu, Li Chun Yang, Ling‐Ling Chen · 2024 · Molecular Cell
  71. Engineered circular RNA-based DLL3-targeted CAR-T therapy for small cell lung cancer
    Jingsheng Cai, Zheng Liu, Shaoyi Chen, Jingwei Zhang, Haoran Li, Xun Wang, Yang Feng, Shaodong Wang, Xiao Li, Yun Li et al. · 2025 · Experimental Hematology and Oncology
  72. Circular RNAs; powerful microRNA sponges to overcome diabetic nephropathy
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  73. Pros and Cons of In Vitro Methods for Circular RNA Preparation
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  74. Viral non-coding RNAs: Stealth strategies in the tug-of-war between humans and herpesviruses
    Takanobu Tagawa, Anna Serquiña, Insun Kook, Joseph M. Ziegelbauer · 2020 · Seminars in Cell and Developmental Biology
  75. Advances in mRNA-based drug discovery in cancer immunotherapy
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  76. Circular RNAs: implications of signaling pathways and bioinformatics in human cancer
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  78. Clean-PIE: a novel strategy for efficiently constructing precise circRNA with thoroughly minimized immunogenicity to direct potent and durable protein expression
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  79. Self-splicing RNA circularization facilitated by intact group I and II introns
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  80. Circular RNA as an Additional Player in the Conflicts Between the Host and the Virus
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  86. Recent advances in understanding circular RNAs
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  87. Insights into the Evolving Roles of Circular RNAs in Cancer
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  88. Differences in the immunogenicity of engineered circular RNAs
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  89. Functional Involvement of circRNAs in the Innate Immune Responses to Viral Infection
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