SLC19A1 is an importer of the immunotransmitter cGAMP.
Ritchie, Christopher, Cordova, Anthony F., Hess, Gaelen T., Bassik, Michael C., Li, Lingyin·2019·Molecular Cell
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- Profiling Nucleotide Signalling Pathways and STING Agonist Activity with a Nucleotide LibraryIndra Bekere, Rupert Öllinger, Marie Rose Schrimpf, Roland Rad, Carina C. de Oliveira Mann · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
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- Therapeutic intranasal delivery of NanoSTING provides broad protection against seasonal and highly pathogenic influenza strainsAnkita Leekha, Kate Reichel, Brett L. Hurst, Navin Varadarajan · 2026 · Antiviral Research
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- Identification of cGAS-like receptors and characterization of STING mediated NF-κB activation in Drosophila melanogasterKasper Grønbjerg Winther · 2024 · theses.fr (ABES)
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- Inhibiting STING1 promotes recovery of cardiac function and structure after diabetic myocardial infarction by facilitating angiogenesisXinyue Wang, Yue Cai, Jia Xu, Guangyao Zang, Xiaomei Ren, Wenwen Sun, Lihua Li, Tao Zheng, Zhongqun Wang · 2026 · Cellular Signalling
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- STING agonists in tumor therapy: structural pharmacology, determinants of productive activation, and barrier-matched therapeutic strategiesCan Li, Lanxiang Wu · 2026 · Biochemical Pharmacology
- STING agonist profiling by nucleotide library defines structural determinants of cyclic dinucleotide recognitionIndra Bekere, Yuliia Hubarzhevska, Sabrina V. Egender, Patrick K. Quoika, Rupert Öllinger, Marie Rose Schrimpf, Roland Rad, Martin Zacharias, Carina C. de Oliveira Mann · 2026 · iScience
- Pharmacological targeting of the extracellular cGAMP–ENPP1 axis in cancer immunotherapy: mechanisms, biomarkers, and translational strategiesKailang Mu, Rui-qi Liao, Jun-li Xie, Xiao-min Tang, Yu-chen Liu, Gang Liu, Zhi-gang Ju, Lu Zhang, Yuan Yuan, Yu-xin Pang · 2026 · European Journal of Pharmacology
- The cGAS–STING pathway in pulmonary infectious and sterile inflammation: differences, connections, and therapeutic implicationsChenglin Liu, 杨蓝楠, Jingjing Yang, Junyan Wang, Jiamin Zhao, Xia Ding, Qian Ni · 2026 · Frontiers in Immunology
- The cGAS-STING pathway in inflammaging and neuroinflammationChufan Zhang, Chaxian Liu, Yingbo Zhao, Hanze Wang, Ziyuan Fang, Ziqian He, Ying Mao, Hui Yang · 2026 · Science China Life Sciences
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- Cyclic di-GMP in E. coli: Roles in pathogenesis, host-pathogen interactions, and therapeutic potentialsBeibei Zhang, Jiangang Hu, Xinyu Wang, Weiqi Guo, Wei Zuo, Jingjing Qi, Mingxing Tian, Yanqing Bao, Lei Deng, Shaohui Wang · 2026 · Microbiological Research
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- Genetic variation in macrophage-restricted FOLR2 is associated with neurodevelopmental and reproductive immune phenotypesElizabeth A. Jasper, James Jaworski, Yuan Luo, Bahram Namjou Khales, Atlas Khan, Digna R. Velez Edwards, David Michael Aronoff · 2026 · Frontiers in Immunology
- ENPP1 buffers extracellular cGAMP in brown adipose tissue to limit insulin resistanceSongnan Wang, Yingjie Guo, Weidong An, J. Michelle Lee, Yu Li, Valentino Sudaryo, Jacqueline A. Carozza, Gabriel Grenot, Gemini M. Skariah, Saranya Chidambaranathan Reghupaty et al. · 2026 · Cell Reports
- SPARCS enables scalable recovery of complex image-based phenotypes for genetic screeningNiklas Arndt Schmacke, Sophia Clara Mädler, Georg Wallmann, Andreas Metousis, Varvara Varlamova, Sophia Steigerwald, Sarah Babette Christ, Marleen Bérouti, Hartmann Harz, Heinrich Leonhardt et al. · 2026 · Cell
- An evidence-to-claim framework for cGAS–STING and AIM2 in atherosclerosisLin Lu, Hui Lin, Peng Zhang, Yun Li, Jie Zhang · 2026 · Frontiers in Cell and Developmental Biology
- BindingDB Entry 50011909: Synthesis and biological evaluation of all possible inosine-mixed cyclic dinucleotides that activate different hSTING variants.BindingDB · 2022 · UC San Diego
- BindingDB Entry 50007948: The Druggability of Solute Carriers.BindingDB · 2021 · UC San Diego