The DOI matches its Crossref record; 153 of the 153 references it cites were found in a registry or an index.
How RNA-Binding Proteins Interact with RNA: Molecules and Mechanisms
Open accessAbstract
SUMMARY RNA binding proteins (RBPs) comprise a large class of over 2000 proteins that interact with transcripts in all manner of RNA-driven processes. The structures and mechanisms that RBPs use to bind and regulate RNA are incredibly diverse. In this review we take a look at the components of protein-RNA interaction, from the molecular level to multi-component interaction. We first summarize what is known about protein-RNA molecular interactions based on analyses of solved structures. We additionally describe software currently available for predicting protein-RNA interaction and other resources useful for the study of RBPs. We then review the structure and function of seventeen known RNA binding domains and analyze the hydrogen bonds adopted by protein-RNA structures on a domain by domain basis. We conclude with a summary of the higher-level mechanisms that regulate protein-RNA interactions.
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Metadata
- Authors
- Corley, M., Burns, M. C., & Yeo, G. W.
- Venue
- Molecular Cell
- Publisher
- Elsevier BV
- Published
- 2020-04
- Volume
- 78
- Issue
- 1
- Pages
- 9-29
- ISSN
- 1097-2765 (ISSN-L)
- OpenAlex
- W3014677172
- Cited by
- 843
- References
- 153
- FWCI
- 25.59
- Type
- journal article
- Language
- en
- Open access
- bronze
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