The DOI matches its Crossref record; 84 of the 84 references it cites were found in a registry or an index.
The Impact of Systemic Inflammation on Neurodevelopment
Open accessAbstract
Inflammatory mediators affect the brain during development. Neurodevelopmental disorders such as autism spectrum disorders, cognitive impairment, cerebral palsy, epilepsy, and schizophrenia have been linked to early life inflammation. Recent advances have shown the effects of systemic inflammation on children’s neurodevelopment. We discuss the potential mechanisms by which inflammatory molecules can exert their effects on the developing brain and consider the roles of MHC class I molecules, the HPA axis, glial cells, and monoamine metabolism. Methods to prevent the effects of cytokine imbalance may lead to the development of new therapeutics for neuropsychiatric disorders. Future research should focus on identifying at-risk individuals and early effective interventions to prevent long-term neurodevelopmental disabilities.
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1 retracted
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Cited by
Wang, S., Chen, L., Ran, H., Che, Y., Fang, D., Sun, H., Peng, J., Liang, X., & Xiao, Y. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.917552 · Cited by 94
Stolp, H. B., Fleiss, B., Arai, Y., Supramaniam, V., Vontell, R., Birtles, S., Yates, A. G., Baburamani, A. A., Thornton, C., Rutherford, M., et al. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.00955 · Cited by 85
Lee, H., Hsu, J.-W., Tsai, S.-J., Huang, K.-L., Bai, Y.-M., Su, T.-P., Chen, T.-J., & Chen, M.-H. (2023) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-021-01860-0 · Cited by 23
Liang, S.-C., Sun, C.-K., Chang, C.-H., Cheng, Y.-S., Tzang, R.-F., Chiu, H.-J., Wang, M. Y., Cheng, Y.-C., & Hung, K.-C. (2024) · BJPsych Open · doi:10.1192/bjo.2023.645 · Cited by 20
Metadata
- Authors
- Jiang, N. M., Cowan, M., Moonah, S. N., & Petri, W. A.
- Venue
- Trends in Molecular Medicine
- Publisher
- Elsevier BV
- Published
- 2018-09
- Volume
- 24
- Issue
- 9
- Pages
- 794-804
- ISSN
- 1471-4914 (ISSN-L)
- OpenAlex
- W2814143751
- Cited by
- 328
- References
- 84
- FWCI
- 2.06
- Type
- journal article
- Language
- en
- Open access
- green
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- Jiang, N. M., Cowan, M., Moonah, S. N., & Petri, W. A. (2018). The Impact of Systemic Inflammation on Neurodevelopment. Trends in Molecular Medicine. https://doi.org/10.1016/j.molmed.2018.06.008
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.