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Cited by 328

The DOI matches its Crossref record; 84 of the 84 references it cites were found in a registry or an index.

The Impact of Systemic Inflammation on Neurodevelopment

Open access
Jiang, Nona M., Cowan, Maureen, Moonah, Shannon N., Petri, William A.·2018·Trends in Molecular Medicine

Abstract

Inflammatory mediators affect the brain during development. Neurodevelopmental disorders such as autism spectrum disorders, cognitive impairment, cerebral palsy, epilepsy, and schizophrenia have been linked to early life inflammation. Recent advances have shown the effects of systemic inflammation on children’s neurodevelopment. We discuss the potential mechanisms by which inflammatory molecules can exert their effects on the developing brain and consider the roles of MHC class I molecules, the HPA axis, glial cells, and monoamine metabolism. Methods to prevent the effects of cytokine imbalance may lead to the development of new therapeutics for neuropsychiatric disorders. Future research should focus on identifying at-risk individuals and early effective interventions to prevent long-term neurodevelopmental disabilities.

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Crossref · 10.1016/j.molmed.2018.06.008

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Metadata

Authors
Jiang, N. M., Cowan, M., Moonah, S. N., & Petri, W. A.
Venue
Trends in Molecular Medicine
Publisher
Elsevier BV
Published
2018-09
Volume
24
Issue
9
Pages
794-804
ISSN
1471-4914 (ISSN-L)
OpenAlex
W2814143751
Cited by
328
References
84
FWCI
2.06
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: The Impact of Systemic Inflammation on Neurodevelopment. https://app.cochat.ai/papers/10.1016/j.molmed.2018.06.008
The paper
Jiang, N. M., Cowan, M., Moonah, S. N., & Petri, W. A. (2018). The Impact of Systemic Inflammation on Neurodevelopment. Trends in Molecular Medicine. https://doi.org/10.1016/j.molmed.2018.06.008

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.