The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Gold nanoparticle mediated cancer immunotherapy
Open accessAbstract
Significant progress has been made in the field of cancer immunotherapy, where the goal is to activate or modulate the body’s immune response against cancer. However, current immunotherapy approaches exhibit limitations of safety and efficacy due to systemic delivery. In this context, the use of nanotechnology for the delivery of cancer vaccines and immune adjuvants presents a number of advantages such as targeted delivery to immune cells, enhanced therapeutic effect, and reduced adverse outcomes. Recently, gold nanoparticles (AuNP) have been explored as immunotherapy carriers, creating new AuNP applications that merit a critical overview. This review highlights recent advances in the development of AuNP mediated immunotherapies that harness AuNP biodistribution, optical properties and their ability to deliver macromolecules such as peptides and oligonucleotides. It has been demonstrated that the use of AuNP carriers can improve the delivery and safety of immunotherapy agents, and that AuNP immunotherapies are well suited for synergistic combination therapy with existing cancer therapies like photothermal ablation.
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Cites
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Gabrilovich, D. I., & Nagaraj, S. (2009) · Nature Reviews Immunology · doi:10.1038/nri2506 · Cited by 6,753
Renal clearance of quantum dots
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Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death
Casares, N., Pequignot, M. O., Tesniere, A., Ghiringhelli, F., Roux, S., Chaput, N., Schmitt, E., Hamai, A., Hervas-Stubbs, S., Obeid, M., et al. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20050915 · Cited by 1,512
Cited by
Gold Nanoparticles for Photothermal Cancer Therapy
Vines, J. B., Yoon, J.-H., Ryu, N.-E., Lim, D.-J., & Park, H. (2019) · Frontiers in Chemistry · doi:10.3389/fchem.2019.00167 · Cited by 906
Riley, R. S., & Day, E. S. (2017) · WIREs Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1449 · Cited by 801
Current trends in using polymer coated gold nanoparticles for cancer therapy
Muddineti, O. S., Ghosh, B., & Biswas, S. (2015) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2015.02.038 · Cited by 259
Metadata
- Authors
- Almeida, J. P. M., Figueroa, E. R., & Drezek, R. A.
- Venue
- Nanomedicine: Nanotechnology, Biology and Medicine
- Publisher
- Elsevier BV
- Published
- 2014-04
- Volume
- 10
- Issue
- 3
- Pages
- 503-514
- ISSN
- 1549-9634 (ISSN-L)
- OpenAlex
- W2088317237
- Cited by
- 236
- References
- 4
- FWCI
- 8.15
- Type
- journal article
- Language
- en
- Open access
- green
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- Almeida, J. P. M., Figueroa, E. R., & Drezek, R. A. (2014). Gold nanoparticle mediated cancer immunotherapy. Nanomedicine: Nanotechnology, Biology and Medicine. https://doi.org/10.1016/j.nano.2013.09.011
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